• Journal of Technologic Dentistry
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• v.30 no.1
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• pp.97-107
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• 2008

Objectives; The purpose of the present study is to investigate the difference in levels of satisfaction between dental laboratory owners and employed dental technicians in the area of dental laboratory management. Methods; The samples of seventy-one dental laboratory owners and sixty-six employed dental technicians were selected in a blinded and random manner. Data was collected through self-administered questionnaires and analyzed using average values, the t-test and multiple regression. Results; 1) There was no significant difference in the average values of general satisfaction levels related to dental laboratory management between dental lab owners and employees. 2) The average values of satisfaction levels in 11 specific items scored 'above average' among dental lab owners and 'average' among employees. 3) The average values of satisfaction levels in 10 specific items except for 'trust and respect' showed a significant difference between dental lab owners and employees. 4) Important factors which influenced the satisfaction level of dental lab owners were 'trust and respect' and 'improvement of employee's benefits'. In the employees group, 'trust and respect', 'improvement of employee's benefits' and 'technical information support' were important factors. Conclusion; The present study revealed that dental laboratory owners and employees have some gaps between the viewpoints in dental laboratory management. This suggests the necessity to improve management in a transparent and economical way. However this study has some limitation in that the sample size was not massive enough.

• Journal of Veterinary Clinics
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• v.38 no.3
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• pp.127-134
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• 2021

Canine atopic dermatitis (CAD) is a genetically predisposed inflammatory and pruritic skin disease presenting characteristic clinical features in dogs. Despite oclacitinib and lokivetmab being commonly used, no study has compared their efficacies in CAD. This study aimed to compare the efficacy, safety, and control of CAD-associated pruritus and skin lesions between oclacitinib and lokivetmab. It also investigated whether switching to lokivetmab from oclacitinib or prednisolone had any benefits. Twenty-five client-owned dogs, newly diagnosed with CAD, were allocated to the oclacitinib (n = 20) and lokivetmab (n = 5) groups and administered oclacitinib (0.4-0.6 mg/kg orally, twice daily for 14 days, then once daily) and lokivetmab (2 mg/kg subcutaneously, every month) for 8 weeks, respectively. The switching group included five dogs previously administered with oclacitinib (n = 4) or prednisolone (n = 1) who were switched to lokivetmab directly at the start of the study. The pruritus visual analog scale (PVAS) and Canine Atopic Dermatitis Extent and Severity Index (CADESI-04) values were surveyed at weeks 0, 4, and 8. Oclacitinib and lokivetmab significantly reduced the PVAS and CADESI-04 scores. Switching from oclacitinib or prednisolone to lokivetmab maintained the severity of pruritus (4 weeks: p = 0.068; 8 weeks: p = 0.068) and dermatitis (4 weeks: p = 0.144; 8 weeks: p = 0.068) at the levels measured at baseline. Thus, both oclacitinib and lokivetmab reduced CAD-associated pruritus by a similar degree. Switching to lokivetmab maintained the severity of pruritus and dermatitis at the same level as the previous treatment.

• 한국정보디스플레이학회:학술대회논문집
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• 2009.10a
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• pp.181-183
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• 2009

Comparative study of the dependence of the firing voltage of MgSrO and MgCaO protective layers on chemical composition was carried out. It was observed that the firing voltage increases when CaO/MgO or SrO/MgO ratio increases.

• Proceedings of the Korea Environmental Mutagen Society Conference
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• 2003.10a
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• pp.130-130
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• 2003

• Proceedings of the Korean Institute of Communication Sciences Conference
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• 2006.07a
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• pp.729-729
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• 2006

• Proceedings of the Korea Society of Environmental Biology Conference
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• 2004.05a
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• pp.28-28
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• 2004

• Proceedings of the PSK Conference
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• 2000.04a
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• pp.130.1-130.1
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• 2000

• The Korean Journal of Physiology and Pharmacology
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• v.28 no.3
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• pp.219-227
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• 2024

Bladder cancer remains the 10th most common cancer worldwide. In recent years, metformin has been found to have potential anti-bladder cancer activity while high concentration of IC₅₀ at millimolar level is needed, which could not be reached by regular oral administration route. Thus, higher efficient agent is urgently demanded for clinically treating bladder cancer. Here, by conjugating artesunate to metformin, a novel artesunate-metformin dimer triazine derivative AM2 was designed and synthesized. The inhibitory effect of AM2 on bladder cancer cell line T24 and the mechanism underlying was determined. Anti-tumor activity of AM2 was assessed by MTT, cloning formation and wound healing assays. Decreasing effect of AM2 on lipogenesis was determined by oil red O staining. The protein expressions of Clusterin, SREBP1 and FASN in T24 cells were evaluated by Western blotting. The results show that AM2 significantly inhibited cell proliferation and migration at micromolar level, much higher than parental metformin. AM2 reduced lipogenesis and down-regulated the expressions of Clusterin, SREBP1 and FASN. These results suggest that AM2 inhibits the growth of bladder cancer cells T24 by inhibiting cellular lipogenesis associated with the Clusterin/SREBP1/FASN signaling pathway.

• Journal of The Korean Association For Science Education
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• v.9 no.1
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• pp.75-89
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• 1989

Secondary schools in Korea have been faced with several critical problems with regard to science education. Among them one of the most fundamental problems is associated with laboratory-based science education. There fore as a part of research project for the improvement of science education in secondary schools, this study had its abjectives to inquire into the following areas related to laboratory experiment. ${\circ}$Survey and analysis of theoretical backgrounds for science teaching focused on laboratory experiments. ${\circ}$Status survey of experiment-based science teaching in high schools. ${\circ}$Development of model for improving experiment-based science teaching. In order to fulfill these objectives this study used methods of eiterature review, survey, and interviews. The major finding are as follows : ${\circ}$Some topic for laboratory experiments as oppeared in the textbooks are not appropriate in the light of sience curricular operations in high schools. ${\circ}$In some schools equipments and facilities of school laboratories are for from sufficiency. ${\circ}$Laboratory experiments are not financially supportel for ideal science teach in both middle schools and high schools. These are not on exhaustive list of findings from this study More finding and teaching model for improvement of science education are also described in this paper.

• Journal of Plant Biotechnology
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• v.5 no.1
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• pp.59-61
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• 2003

Petiole explants from 20 cultivars of Catharanthus roseus were cultured on various shoot-inducing media to assess their competence for adventitious shoot formation. After eight weeks of culture on Murashige and Skoog' s medium supplemented with 4.4 $\mu\textrm{m}$6-benzyladenine and 0.5 $\mu\textrm{m}$ $\alpha$-naphthaleneacetic acid, petiole explants from 'Cooler Icy Pink' exhibited the greatest frequency of adventitious shoot formation at 40%, which was followed by 'Little Bright Eye'. By comparing with a previous study on assessment of competence for adventitious shoot formation in hypocotyl explant cultures of various cultures, it is indicated that the relative degree of their competence among cultivars varies to the organ used for the source of explant. Excised adventitious shoots were readily rooted on half-strength MS basal medium. Regenerated plantlets were successfully transplanted to potting soil and grown to maturity in a greenhouse.