• Wind and Structures
• /
• v.10 no.2
• /
• pp.209-214
• /
• 2007

• Proceedings of the PSK Conference
• /
• 2000.10a
• /
• pp.161.2-161.2
• /
• 2000

• Korean Journal of Microbiology
• /
• v.23 no.1
• /
• pp.49-55
• /
• 1985

The survival of Escherichia coli in river water was comparatively studied by laboratory and in sity study methods. The survival by two methods was evaluated as a function of E. coli strain, indigeneous predator, level of water pollution, and water temperature in different season. The survival rate of E. coli examined by laboratory method was lower than that by in situ method. That was found to be due to the fact that higher number of predator was maintained in labortory study than in in situ study. The survival rates of E. coli in gradually polluted river waters could be differentiated by in situ study, but not by laboratory study. Therefore, an in situ method rather than labortory method was thought to be a choice of study method for the survival of E. coli in river waters.

• Archives of Pharmacal Research
• /
• v.28 no.6
• /
• pp.680-684
• /
• 2005

Ginseng, the root of Panax ginseng CA Meyer, is well known as a tonic medicine for restoring and enhancing human health. In traditional medicine, ginseng is utilized for the alleviation of emesis, which includes nausea and vomiting. However, it has not yet been demonstrated whether ginseng exhibits in vivo anti-nausea and anti-vomiting properties. In this study, we examined the anti-emetic effect of Korean red ginseng total extract (KRGE) on cisplatin-induced nausea and vomiting using ferrets. Intraperitoneal administration (i.p.) of cisplatin (7.5 mg/kg) induced both nausea and vomiting with one-hour latency. The episodes of nausea and vomiting reached a peak after 1.5 h and persisted for 3 h. Treatment with KRGE via oral route significantly reduced the cisplatin-induced nausea and vomiting in a dose-dependent manner. The anti-emetic effect was 12.7 $\pm$ 8.6, 31.8 $\pm$ 6.9, and 67.6 $\pm$ 4.0$\%$ with doses of 0.3, 1.0, and 3.0 g/kg of KRGE, respectively. Pretreatment with KRGE via oral route 1 and 2 h before cisplatin administration also significantly attenuated the cisplatin-induced nausea and vomiting. However this did not occur with a pretreatment 4 h before cisplatin administration. These results are supportive of KRGE being utilized as an anti-emetic agent against nausea and vomiting caused by chemotherapy (i.e. cisplatin).

• Journal of Technologic Dentistry
• /
• v.9 no.1
• /
• pp.5-19
• /
• 1987

The factors which impact on the productivity of medical organization are technique, manager, raw materials, management style, manpower structure, job construction, and so on. Human resources is the most important factor among them, but the productivity of serice organization can not be measured easily. The purpose of this study was to verify the effect of laboratory status, the degree of job cognition, and stress on the productivity of dantal prosthetic products, and to fine out the factors which impact on the productivity. The results were as follows: 1. The job characteristice of crown bridge laboratory part and porcelain laboratory part similar to each other. Also partial denture laboratory part and complete denture laboratory part were similar to each other. But that of orthodontic laboratory part was different from other. 2. the degree of job cognition made significant difference statisfically according to job characteristics of each dental laboratorise. 3. The correlation coefficient between job cognition of dental laboratory technician and workshop environment was.23, but the correlation between job cognition job stress appeared reversely, its coefficient was-.17. 4. The productivity of technician engaged in dental laboratory was much heigher than that of technician engaged in dental clinical laboratory room, and each were different in the degree of job cognition. 5. the most important factors which impact one the performance productivity of dental laboratory technician were the fact whether he married or not and his status.

• Journal of Korean Elementary Science Education
• /
• v.24 no.3
• /
• pp.268-280
• /
• 2005

Teaching with laboratory activities in school science, which are distinctive characteristic, is placed from other disciplines fur teaming almost 200 hundred years ago. A number of science educators have suggested that there are rich benefits in teaming from using laboratory activities. At these time, however, some educators have begun to seriously question the effectiveness and the role of laboratory activities. There are some causes related to obscure and vague aims of laboratory activities. The purposes of this paper is to review aims of laboratory activities presented in the literatures through historical overview, and to obtain implication for school science. There are various aims of laboratory activities by a number of researchers. Overall synthesizing, there are ffur domains of aims of science teaching through laboratory activities, (a) science knowledge has two sub-domains; scientific content knowledge and procedural knowledge, (b) nature of science, (c) science attitude has two sub-domain; scientific attitude and attitude toward science, and (d) ability of scientific inquiry has two sub-domain; manipulative skills and scientific thinking. But, it is necessary to continue the following study in order to obtain the aims of laboratory activities agreed by expert community, and setting up of lists of aims of laboratory activities for students to achieve hierarchies of school science curriculums.

• The Korea Genome Conference
• /
• 2004.07a
• /
• pp.34.2-34.2
• /
• 2004

• Biomedical Science Letters
• /
• v.29 no.4
• /
• pp.242-248
• /
• 2023

Platelets are activated at the sites of vascular injury by a number of molecules, including adenosine diphosphate, collagen and thrombin. The full platelet aggregation is absolutely essential for the normal hemostasis. Glycyrrhiza glabra is a well-known medicinal herb that grows in various parts of the world and is known to have various effects such as antioxidant, anti-inflammatory, anti-atherogenic, anti-osteoporotic and skin-whitening. However, the platelet inhibitory effect of Glycyrrhiza glabra extract (GGE) has not been identified. In this study, we investigated if GGE inhibited platelet aggregation. We observed that GGE inhibited collagen-induced platelet aggregation, Ca²⁺ mobilization, and thromboxane A2 generation. In addition, GGE suppressed phosphorylation of phosphatidylinositol-3 kinase (PI3K), Akt and elevated phosphorylation of inositol 1,4,5-trisphosphate receptor (IP3R), vasodilator stimulated phosphoprotein (VASP). Taken together, GGE showed strong antiplatelet effects and may be used to block platelet-mediated cardiovascular diseases.

• Asian Pacific Journal of Cancer Prevention
• /
• v.13 no.12
• /
• pp.6005-6010
• /
• 2012

Background: Nasopharyngeal carcinoma (NPC) is endemic in Southern Chinese and Southeast Asian populations. Geographical and ethnic clustering of the cancer is due to genetic, environmental, and lifestyle risk factors. This case-control study aimed to identify or confirm both genetic and non-genetic risk factors for NPC in one of the endemic countries, Malaysia. Materials and Methods: A panel of 768 single-nucleotide polymorphisms (SNPs) previously associated with various cancers and known non-genetic risk factors for NPC were selected and analyzed for their associations with NPC in a case-control study. Results: Statistical analysis identified 40 SNPs associated with NPC risk in our population, including 5 documented previously by genome-wide association studies (GWAS) and other case-control studies; the associations of the remaining 35 SNPs with NPC were novel. In addition, consistent with previous studies, exposure to occupational hazards, overconsumption of salt-cured foods, red meat, as well as low intake of fruits and vegetables were also associated with NPC risk. Conclusions: In short, this study confirmed and/or identified genetic, environmental and dietary risk factors associated with NPC susceptibility in a Southeast Asian population.

• Korean Journal of Clinical Laboratory Science
• /
• v.44 no.4
• /
• pp.210-215
• /
• 2012

Hepatitis virus infection is one of the major problems in Korea. To establish preventive measures for hepatitis A and B virus infection, study on sero-positivity of serum anti-HAV (aHAV) and anti-HBs (aHBs) is needed. The aim of this study was to analyze the sero-positivity and related factors of aHAV and aHBs. We analysed the sero-positivity of serum aHAV and aHBs using ICA (Immunochromatography Assay) method from 102 university students and employees and questionnaire survey was obtained characteristics, vaccination history, past history test, knowledge and information sources of the study subjects. Overall sero-positivity rates of serum aHAV and aHBs were 20.6% and 52.9%, respectively. The sero-positivity rate of aHBs was significantly different by gender (M, 34.9%; F,66.1%) and that of aHAV was significantly different by age (20 age group, 2.7%; 30 age group, 14.3%; 40 age group, 70%; 50 age group, 91.7%). Overall sero-positivity rates of serum aHAV and aHBs by vaccination history rates were 4.9% and 43.1%, respectively. Overall sero-positivity rates of serum aHAV and aHBs by past history test were 10.8% and 52.9%, respectively. Sero-positivity rates of serum aHAV was low in university students. The results of this study could be used effectively as a basic data for establishing effective preventive measures for hepatitis A including vaccination.