• Structural Engineering and Mechanics
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• 제27권6호
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• pp.697-711
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• 2007

Though extensive research has been carried out for the ultimate strength of steel reinforced concrete (SRC) members under static and cyclic load, there was only limited information on the applied analysis models. Modeling of the inelastic response of SRC members can be accomplished by using a microcosmic model. However, generally used microcosmic model, which usually contains a group of parameters, is too complicated to apply in the nonlinear structural computation for large whole buildings. The intent of this paper is to develop an effective modeling approach for the reliable prediction of the inelastic response of SRC columns. Firstly, five SRC columns were tested under cyclic static load and constant axial force. Based on the experimental results, normalized trilinear skeleton curves were then put forward. Theoretical equation of normalizing point (ultimate strength point) was built up according to the load-bearing mechanism of RC columns and verified by the 5 specimens in this test and 14 SRC columns from parallel tests. Since no obvious strength deterioration and pinch effect were observed from the load-displacement curve, hysteresis rule considering only stiffness degradation was proposed through regression analysis. Compared with the experimental results, the applied analysis model is so reasonable to capture the overall cyclic response of SRC columns that it can be easily used in both static and dynamic analysis of the whole SRC structural systems.

• Asian Pacific Journal of Cancer Prevention
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• 제13권12호
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• pp.6523-6526
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• 2012

Objective: This study was designed to investigate treatment efficacy and side effects of concomitant Aisu$^{(R)}$ (docetaxel) with three-dimensional conformal external beam radiotherapy for the treatment of inoperable patients with esophageal cancer. Methods: Inoperable patients were treated with three-dimensional conformal external beam radiotherapy (5/week, 2 GY/day, and total dose 60GY) plus docetaxel ($30-45mg/m^2$, iv, d1, 8). Results: Twenty eight patients met the study eligibility criteria and the response rate was evaluated according to RICIST guidelines. Among 28 patients, 2 achieved CR, 22 PR, 3 SD and 1 patient was documented PD. Mild gastrointestinal reaction and bone marrow suppression were also documented. All treatment related side effects were tolerable. Conclusion: Three-dimensional conformal external beam radiotherapy combined with docetaxel is an active and safe regimen for inoperable patients with esophageal cancer.

• Asian-Australasian Journal of Animal Sciences
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• 제26권5호
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• pp.609-624
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• 2013

The objective of this study was to get a comprehensive understanding of how genes in chicken shell gland modulate eggshell strength at the early stage of active calcification. Four 32-week old of purebred Xianju hens with consistent high or low shell breakage strength were grouped into two pairs. Using Affymetrix Chicken Array, a whole-transcriptome analysis was performed on hen's shell gland at 9 h post oviposition. Gene ontology enrichment analysis for differentially expressed (DE) transcripts was performed using the web-based GOEAST, and the validation of DE-transcripts was tested by qRT-PCR. 1,195 DE-transcripts, corresponding to 941 unique genes were identified in hens with strong eggshell compared to weak shell hens. According to gene ontology annotations, there are 77 DE-transcripts encoding ion transporters and secreted extracellular matrix proteins, and at least 26 DE-transcripts related to carbohydrate metabolism or post-translation glycosylation modification; furthermore, there are 88 signaling DE-transcripts. GO term enrichment analysis suggests that some DE-transcripts mediate reproductive hormones or neurotransmitters to affect eggshell quality through a complex suite of biophysical processes. These results reveal some candidate genes involved with eggshell strength at the early stage of active calcification which may facilitate our understanding of regulating mechanisms of eggshell quality.

• Asian Pacific Journal of Cancer Prevention
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• 제13권7호
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• pp.3191-3194
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• 2012

Objective: To investigate the association between the change of IGF-2 level in serum after transcatheter arterial chemoembolization (TACE) and hepatocellular carcinoma (HCC) progression, especially in relation to metastasis. Methods: IGF-2 in serum was measured by quantitative sandwich enzyme-linked immunosorbent assaybefore, 3 days and 4 weeks after TACE in 60 patients with HCC. The occurrence of HCC metastasis was also evaluated, 3 months after TACE. Results: (1) The average serum level of IGF-2 in the 60 patients with HCC was $136.5{\pm}87.3$ pg/ml; (2) A tendency for increase was observed with heterogenous uptake of octreotide and portal vein thrombosis. Metastatic foci were found in 37/38 patients in the group with IGF-2 increasing (97.0%), in contrast to 3/22 (13.6%) patients with IGF-2 decrease. Conclusion: The increase of IGF-2 level in serum appears to be associated with the occurrence of metastatic HCC after TACE and chemotherapy.

• Asian Pacific Journal of Cancer Prevention
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• 제15권15호
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• pp.6103-6108
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• 2014

Many studies have reported ${\beta}$-catenin involvement in the development of esophageal carcinoma (EC), but its prognostic significance for EC patients remains controversial. Therefore, we conducted this meta-analysis to explore the issue in detail. After searching PubMed, EMBASE, Web of Science, and Chinese Biomedical Literature Database, we included a total of ten relevant studies. We pooled the overall survival (OS) data using RevMan 5.2 software. The results showed that aberrant expression of ${\beta}$-catenin was associated with a significant increase of mortality risk (hazard ratio 1.71, 95%CI 1.46-2.01; p<0.00001). Subgroup analyses further suggested that aberrant expression of ${\beta}$-catenin resulted in poor OS of EC patients regardless of histological type of EC, study location or criteria for aberrant expression of ${\beta}$-catenin, and the sensitivity analyses revealed that the result was robust. The meta-analysis revealed that aberrant expression of ${\beta}$-catenin could be a predicative factor of poor prognosis for EC patients.

• Asian-Australasian Journal of Animal Sciences
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• 제17권5호
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• pp.583-587
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• 2004

The 7 sheep microsatellite markersOarFCB48, OarAE101, MAF33, OarFCB11, MAF70, OarFCB304 and OarFCB128, which were located on chromosomes 2, 4, 6, 9, 17 and 19, were selected to PCR in Hu sheep, Tong sheep and their closely related species,the goat. They were studied with the amplifying result of 7 microsatellite sites of Hu Sheep, Tong Sheep and goats, the data of allele number and range of allele' size of amplifying were analyzed with ANOVA. The results showed that there were no significant differences (p<0.05) in microsatellite DNA sites among 3 populations. Concerning the conservation of microsatellites in closely related species, selecting microsatellite sites located on the chromosome where the Robertsonian fusion was caused between sheep and goat, may be used in research into genetic differentiation and evolutionary relationships between sheep and goats.

• 한국멀티미디어학회논문지
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• 제21권3호
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• pp.415-422
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• 2018

Advances of telecommunication technology bring various changes in journalism field. Reporters started to gather, edit, and transmit content to main server in media company using hand-held smart media and notebook computer. This paper tried to testify valid bit-rate of visual news content using LTE network and mobile phone. Field news like natural disasters need real-time transmission of video content. But broadcasting company normally use heavy ENG system and transmission satellite trucks. We prepared and experimented different types of visual content that has different bit-rates. Transmission tool was LU-60HD mobile system of LiveU Corporation. Transmission result shows that bit-rate of 2Mbps news content is not suitable for broadcasting and VBR (Variable Bit Rate) transmission has better definition quality than CBR (Constant Bit Rate) method. Three different bit-rate of VBR transmission result shows that 5Mbps clip has better quality than 1Mbps and 3Mbps. The higher bit-rate, the better video quality. But if the content has much movements, that cause delay and abnormal quality of video. So optimizing the balance between stability of signal and quality of bit-rate is crucial factor of real-time broadcasting news gathering business.

• Journal of Power Electronics
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• 제16권2호
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• pp.425-435
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• 2016

This paper presents a comprehensive theoretical analysis and an accurate calculation method of the dead-time required to achieve zero-voltage-switching (ZVS) in a battery charger with the phase-shifted full-bridge (PSFB) topology. Compared to previous studies, this is the first time that the effects of nonlinear output filter inductance, varied Miller Plateau length, and blocking capacitors have been considered. It has been found that the output filter inductance and the Miller Plateau have a significant influence on the dead-time for ZVS when the load current varies a lot in battery charger applications. In addition, the blocking capacitor, which is widely used to prevent saturation, reduces the circulating current and consequently affects the setting of the dead-time. In consideration of these effects, accurate analytical equations of the dead-time range for ZVS are deduced. Experimental results from a 1.5kW PSFB battery charger prototype shows that, with the proposed analysis, an optimal dead-time can be selected to meet the specific requirements of a system while achieving ZVS over wide load range.

• 한국가시화정보학회지
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• 제10권1호
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• pp.27-33
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• 2012

This paper describes a new design of small-scale horizontal wind blade, called spiral wind turbine blade. Theoretical and numerical approaches on the prediction of aerodynamic performance of the blade have been conducted. A theoretical equation is successfully derived using the angular momentum equation to predict aerodynamic characteristics according to the design shape parameters of spiral blade. To be compared with the theoretical value, a numerical simulation using ANSYS CFX v12.1 is performed on the same design with the theoretical one. Large scale tip vortex is captured and graphically presented in this paper. The TSR-$C_p$ diagram shows a typical parabolic relation in which the maximum efficiency of the blade approximately 25% exists at TSR=2.5. The numerical simulation agrees well with that of the theoretical result except at the low rotational speed region of 0~20 rad/s.

• Korean Journal of Acupuncture
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• 제25권1호
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• pp.51-60
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• 2008

Objectives : The aim of this study was to investigate the mechanism and the clinical significance of prohibition of acupuncture of LI4 and SP6 during the period of pregnancy. Methods : It was investigated the prohibition of acupuncture during the period of pregnancy based on the literature reviews. Previous studies identified the acupuncture treatment of animal and clinical studies during the period of pregnancy and labor in China Academic Journal(CAJ). These papers were classified and investigated to clarify the rationale of the prohibition of acupuncture during the period of pregnancy. Results and Conclusions : The contraindicated points during the period of pregnancy are Hapgok (LI4), Samumgyo (SP6), Songmun (CV5), Kwanwon (CV4), Sosang (LU11), Chium (BL67), Kollyun (BL60). The uterine contraction can be induced by the stimuli of Hapgok (LI4) via endocrine system and Samumgyo (SP6) via nervous system. Both Hapgok (LI4) and Samumgyo (SP6) also can be used in various diseases such as induction of abortion, facilitation of parturition, stabilization of embryos, cross birth and so on.