• Korean Journal of Acupuncture
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• v.24 no.3
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• pp.205-221
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• 2007

Objectives : Aims of this study is to investigate the effects of $LU8{\cdot}KI7$ in rat induced by experimental focal ischemia. Materials and methods : The focal ischemia was induced by intraluminal filament insertion into middle cerebral artery. The groups divided into 6groups, control; no therapy group after ischemia-induced, AT1; acupuncture therapy group at $LU8{\cdot}KI7$ after ischemia-induced, AT2; acupuncture therapy at $LU8{\cdot}KI7$ bilaterally and the needle was twirled and rotated forward with the thumb of the right hand 9times, AT3; acupuncture therapy at $LU8{\cdot}KI7$ bilaterally and the needle was twirled and rotated forward with the forefinger of the right hand 9times, AT4; acupuncture therapy at$LU8{\cdot}KI7$ bilaterally and the needle was inserted to the direction following the flowing route of the meridian(digital direction), AT5; acupuncture therapy at $LU8{\cdot}KI7$ bilaterally, the needle was inserted to the direction following the flowing route of the meridian(digital direction) and the needle was twirled and rotated forward with the thumb of the right hand 9times. Acupuncture therapy was carried out 7times during 2weeks after focal ischemia-induced. The anti-apoptotic and neuroprotective effects of acupuncture are observed by Bax, Bcl-2, mGluR5, cytochrome c, Cresyl violet and ChAT-stain. Results : The intensity of Bax was decreased in AC1, AC4, AC5 group, was increased in AC2, AC3 group. The intensity of Bcl-2 was increased in AC2, AC3, AC4, AC5 group. The intensity of mGluR5 was decreased in AC1 group, was increased in AC4, AC5 group. The intensity of Cytochrome c was increased in ACI, AC2 group, was decreased in AC4, AC5 group. The density of neurons stained by Cresyl violet was increased in all group without control group. The density of ChAT was increased in AC2, ACS group. Conclusions : Our study suggests that AC5 group show anti-apoptotic and neuroprotective effects on cholinergic neuron in focal cerebral ischemia of the stroke in rats.

• Journal of Oriental Neuropsychiatry
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• v.19 no.2
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• pp.1-14
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• 2008

Objective : This study was designed for find corelation between behavior and physical symptoms in child. Physical symptoms appearing related with weak viscera are selected. And behaviors related to selected symptoms are compared that of children with character type defined by jung, c. G. Method: 497 children ( 3-11 years old ) who have visited two oriental clinic ( one is in Gang-Nam Gu Seoul (282 children), the other is in Joong-Rang Gu Seoul (215 children) ) from Jan. to Jul. 2006 were invested through the questionnaires, which were filled by their parents. These questionnaires have 61 yes-no type questions about behaviors on 12 situations, 36 yes no type questions about physical symptoms in 15 categories. 6 questions expected positive answer in child with weak spleen are categorized sp-q and 6 related weak lung, lu-q, 6 related weak kidney, ki-q. Numbers of positive answers in sp-q, lu-q and ki-q are counted so-index, lu-index and ki-index each. Corelation between behavior questions and 3 symptom indexes are measured and questions shown low significance level ( under 5% in pearson corelation, two-tailed ) are selected. Result: 15 behaviors related sp-index, 12 related lu-index, 12 related ki-index are selected and analysed. Conclusion : 1. Behaviors related sp-index is similar to that of Thinking Type children Grouped by jung, c. G.. 2. Behaviors related lu-index is similar to that of Sensation Type. 3. Behaviors related sp-index is similar to that of Feeling Type.

• Current Optics and Photonics
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• v.4 no.3
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• pp.238-246
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• 2020

The heat distribution in crystals in a 2-㎛ acousto-optic Q-switched Tm:LuAG laser pumped by pulsed-laser-diode (pulsed-LD) intermittent-pumping technology was analyzed using COMSOL software. The thermal lensing effect of the Tm:LuAG crystal can be mitigated by pulsed-LD intermittent-pumping techniques. An experimental setup using this kind of approach achieved maximum output energy of 8.31 mJ, minimum pulse width of 101.9 ns, and highest peak power of 81.55 kW, reached at a Q-switched repetition rate of 200 Hz. It offers significant improvement of performance of the output laser beam, compared to pulsed-LD double-ended pumping technology at the same repetition rate.

• Advances in Computational Design
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• v.8 no.3
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• pp.219-236
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• 2023

In this paper, finite element modeling of the laser ultrasonics (LU) process in ablation regime is of interest. The momentum resulting from the removal of material from the specimen surface by the laser beam radiation in ablation regime is modeled as a pressure pulse. To model this pressure pulse, two equations are required: one for the spatial distribution and one for the temporal distribution of the pulse. Previous researchers have proposed various equations for the spatial and temporal distributions of the pressure pulse in different laser applications. All available equations are examined and the best combination of the temporal and spatial distributions of the pressure pulse that provides the most accurate results is identified. This combination of temporal and spatial distributions has never been used for modeling laser ultrasonics before. Then by using this new model, the effects of variations in pulse duration and laser spot radius on the shape, amplitude, and frequency spectrum of ultrasonic waves are studied. Furthermore, the LU in thermoelastic regime is simulated by this model and compared with LU in ablation regime. The interaction of ultrasonic waves with a defect is also investigated in the LU process in ablation regime. Good agreement of the results obtained from the new finite element model and available experimental data confirms the accuracy of the proposed model.

• Journal of the Korean Chemical Society
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• v.44 no.6
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• pp.541-546
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• 2000

Methods to determine L-dopa(L-3,4-dihydroxyphenylalanine) in aqueous solution by spectrofluorimetry based upon the ligand sensitized luminescence of Tb(III) ion L-dopa complex have been studied. Tb(III) ion and Lu(III) ion were used as ligand sensitized fluorescencer and co-fluorescence enhancer, respectively. The effects of excitation wavelength, pH, concentration of Tb(III) ion, concentration of Lu(III) ion and emission wavelength on the fluorescence intensity were investigated. The fluorescence intensity of the Tb(III) ion L-dopa complex was further increased with addition of Lu(III) ion. The calibration curve for L-dopa was linear over the range from 5.0 ${\times}$ $10^{-7}$ M to 1.0${\times}$ $10^{-4}$ M and the detection limit was 4.0 ${\times}$ $10^{-8}$ M under the optimal experimental conditions of 300 nm, 8.0, 1.0 ${\times}$ $10^{-4}$ M and 545 nm for excitation wavelength, pH, concentration of Tb(III) ion and emission wavelength, respectively. When Lu(III) ion was added to Tb(Ⅲ) ion L-dopa complex, the concentration range of linear response and detection limit were 1.0${\times}$$10^{-8}$ M to 2.0 ${\times}$ $10^{-4}$ M and 1.0 ${\times}$ $10^{-9}$ M, respectively under the optimal experimental conditions of 300 nm, 8.5, 1.0 ${\times}$ $10^{-5}$ M, 1.0 ${\times}$ $10^{-5}$ M, 545 nm for excitation wavelength, pH, concentration of Tb(III) ion, concentration of Lu(III) ion and emission wavelength, respectively.

• Journal of the Korean Ceramic Society
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• v.54 no.1
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• pp.70-74
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• 2017

Up-conversion (UC) and down-conversion (DC) luminescence of $LuNbO_4:0.18Yb^{3+}$, $xEr^{3+}$ (x = 0.01-0.07) powders were investigated. Post-annealed powders were composed of a single $LuNbO_4$ phase with a monoclinic fergusonite structure, whereas as-calcined powders contained a small amount of the $Li_3NbO_4$ impurity phase. Under near infrared radiation, the UC spectra of the post-annealed powders exhibited the strong green and weak red emission peaks assigned to the transition of $^2H_{11/2}/^4S_{3/2}$ and $^4F_{9/2}$ to the ground state ($^4I_{15/2}$) of $Er^{3+}$ ions, respectively; the green and red emission intensities were approximately 330 and 270% stronger, respectively, than those of the as-calcined powders. A two-photon UC process was involved in the emission as a result of an energy transfer from $Yb^{3+}$ to $Er^{3+}$. Under ultraviolet radiation, the DC spectra exhibited broad blue and sharp green emission bands. The DC mechanism was explained using self-activated $[NbO_4]^{3-}$ niobates and an energy transfer from $[NbO_4]^{3-}$ to $Er^{3+}$.

• Journal of Acupuncture Research
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• v.27 no.1
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• pp.129-135
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• 2010

Objectives : The purpose of this research was to examine that effect of Sosang($LU_1$)-Eunbaek($SP_1$) bloodletting was similar to effect of Sa-kwan $LI_4$) and Taechung($LR_3$)> acupuncture on pain and discomfort of acute dyspepsia in upper abdomen. Methods : We divided 36 patients with acute dyspepsia into two groups and treated Group A with Sosang($LU_{11}$)-Eunbaek($SP_1$) bloodletting and Group B with Sa-kwan $LI_4$) and Taechung($LR_3$)> acupuncture. Pain and discomfort in upper abdomen was measured by Visual Analogue Scale(VAS) scores of the two groups before treatment and after 15 minutes to treat. Results : Both group A and B represented effective improvement in VAS of pain and discomfort in upper abdomen. And there was no difference between A group and B group statistically. Conclusions : It is suggested that Sosang($LU_{11}$)-Eunbaek($SP_1$) bloodletting may have similar effect compared with Sa-kwan $LI_4$) and Taechung($LR_3$)> acupuncture on acute dyspepsia treatment.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.36 no.3A
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• pp.287-295
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• 2011

Cognitive radio (CR) features opportunistic access to spectrum when licensed users (LU) are not operating. To avoid interference to LU, cognitive users (CU) need to perform spectrum sensing. Because of local shadowing, fading, or limited sensing capability, it is suggested that multiple CUs cooperate to detect LU. In cooperative spectrum sensing, CUs should exchange their sensing data with minimum bandwidth and delay. In this paper, we introduce a novel method to efficiently report sensing data to the central node in an infrastructured OFDM-based CR network. All CUs simultaneously report their sensing data over unique and orthogonal signals on locally available subcarriers. By detecting the signals, the central node can determine subcarrier availability for each CU. Implementation challenges are identified and then their solutions are suggested. The proposed method is evaluated through simulation on a realistic channel model. The results show that the proposed method is feasible and efficient.

• Asian Pacific Journal of Cancer Prevention
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• v.13 no.3
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• pp.821-825
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• 2012

Purpose: Centromere protein H (CENP-H) and Ki67 are overexpressed in some malignancies, but whether they are predictors of survival after primary resection for hypopharyngeal squamous cell carcinoma (HSCC) remains unknown. Methods: We assessed immunohistochemical expression of CENP-H and Ki67 in 112 HSCC specimens collected between March 2003 and March 2005 for analysis by clinical characteristics. The Kaplan-Meier method was used to analyze relapse-free survival and logistic multivariate regression to determine risk factors of relapse-free survival. Cholecystokinin octapeptide assays and flow cytometry were used to examine cell proliferation and apoptosis after siRNA inhibition of CENP-H in HSCC cells. Results: Overall, 50 (44.6%) HSCC specimens showed upregulated CENP-H expression and 69 (61.6%) upregulated Ki67. An increased CENP-H protein level was associated with advanced cancer stage and alcohol history (P=0.012 and P=0.048, respectively) but an increased Ki67 protein level only with advanced cancer stage (P=0.021). Increased CENP-H or Ki67 were associated with short relapse-free survival (P<0.001 or P=0.009, respectively) and were independent predictors of relapse-free survival (P=0.001 and P=0.018, respectively). siRNA knockdown of CENP-H mRNA inhibited cell proliferation and promoted cancer cell apoptosis in vitro. Conclusions: Upregulated CENP-H and Ki67 levels are significantly associated with short relapse-free survival in HSCC. These factors may be predictors of a relapsing phenotype in HSSC cases.

• The Journal of the Korea institute of electronic communication sciences
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• v.16 no.2
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• pp.287-292
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• 2021

In this paper, we propose an efficient CNN application method by analyzing the effect of activation function on the failure diagnosis of the inductive motor stator. Generally, the main purpose of the inductive motor stator failure diagnosis is to prevent the failure by rapidly diagnosing the minute turn short. In the application of activation function, experiments show that the Sigmoid function is 23.23% more useful in accuracy of diagnosis than the ReLu function, although it is shown that ReLu has superiority in overall fixer failure in utilizing the activation function.