• Journal of the Korean Crystal Growth and Crystal Technology
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• v.25 no.3
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• pp.121-126
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• 2015

A novel $Ce^{3+}$ doped $Lu_3MgAl_3SiO_{12}$ phosphor ($Lu_{2.94}Ce_{0.06}MgAl_3SiO_{12}$) was successfully synthesized by a conventional solid-state reaction at $1450^{\circ}C$ for 5 h. The crystal structure of the synthesized phosphor powder was characterized by X-ray diffraction and Rietveld refinement. The prepared phosphor powder showed a broad peak at 550 nm, and the temperature dependence on photoluminescence properties of the prepared $Lu_{2.94}Ce_{0.06}MgAl_3SiO_{12}$ phosphor was investigated from 300 to 525 K. The activation energy for thermal quenching was determined by Arrhenius fitting. The experimental results clearly indicate that prepared $Lu_{2.94}Ce_{0.06}MgAl_3SiO_{12}$ phosphor has great potential for a down-conversion yellow phosphor in white light-emitting diodes.

• Transactions of the Korean Society for Noise and Vibration Engineering
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• v.26 no.1
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• pp.55-62
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• 2016

Nuclear fuels are always exposed to hot temperature and high speed coolant flow during the reactor operation. Thus the fuel rod accompanies small amplitude vibration due to the turbulent flow. The random vibration causes friction between the fuel rod and the grid structure which provides the lateral supports. The friction is critical to the fuel rod fretting wear, and it degrades fuel performance when a severe wear is developed. LuGre friction model is introduced in the paper, and the performance was evaluated comparing to the classical Coulomb model. It is shown that the developed friction force considering the Coulomb friction is not enough to stop or delay the motion while the stick-slip can be simulated using LuGre friction model. Numerical solutions of the two dimensional spacer grid cell model with the modern friction are also reviewed, and it is discussed that the new friction model simulates well the nonlinear mechanism.

• Korean Journal of Veterinary Research
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• v.55 no.1
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• pp.57-60
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• 2015

To investigate kinetics of free $^{177}Lu$ and $^{177}Lu$-labeled thermally cross-linked superparamagnetic iron oxide nanoparticles (TCL-SPION), suspensions were intravenously injected into the tail vein of mice at a dose of $5{\mu}Ci$/mouse or 15 mg/kg body weight, respectively. Free $^{177}Lu$ radioactivity levels were highest in kidney followed by liver and lung 1 day post-injection. $^{177}Lu$-labeled TCL-SPION radioactivity in liver and spleen was significantly higher compared to that of other organs throughout the experimental period (p < 0.05). Radioactivity in blood, brain, and epididymis rapidly declined until 28 days. Based on these results, TCL-SPION could be a safe carrier of therapeutics.

• Journal of Veterinary Clinics
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• v.15 no.1
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• pp.41-45
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• 1998

This study was performed to investigate the serum creative kinase(CK) activity and CK isoenzyme in Jindo dog. Serum CK activity and CK-isoenzyme were analyzed in 53 Jindo dogs of both sexes. The mean value and normal range of serum CK activity were 24.1 lu/$\ell$ and 7-91 lu/$\ell$, respectively, in 29 female dogs, 24.8 lu/$\ell$ and 8-89 lu/$\ell$ in 24 male dogs. The CK activity of the Puppy showed a tendency to be higher than that of the adult. There was no significance between Puppy and adult. Three isoenzymes (CK-MM, CK- BB, and CK-MB) were recognized in serum. The mean percentages of female and male were as follows: 48.31fp and 48.1% for CK-MM, 35.49) and 33.61fp for CK-BB, and 8.2% and 10.1% for CK-MB in the puppy and 46.21% and 46.1 % for CK-MM, 36.3% and 37.6% for CK-BB and 10.5% and 9.5% for CK-MB in the adult.

• Journal of Environmental Science International
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• v.19 no.12
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• pp.1361-1374
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• 2010

The impact of urbanization on local meteorology (e.g., surface temperature, PBL height, wind speed, etc.) in the Greater Seoul Area (GSA) was quantitatively evaluated based on a numerical modeling approach during a 1-month period of 2001 (9 Sep. through 8 Oct. 2001). The analysis was carried out by two sets of simulation scenarios: (1) with the global land use and topographic data from the U.S. Geological Survey (USGS) in 1990s (i.e., LU-USGS case) and (2) with the land use data from the Environmental Geographic Information System (EGIS) along with the 3 sec elevation data from the Shuttle Radar Topography Mission (SRTM) in 2000s (i.e., LU-EGIS case). The extension of urban areas in the GSA (especially, the southern parts of Seoul) accounted for 1.8% in the LU-USGS case and 6.2% in the LU-EGIS case. For the simulations, the surface temperature and PBL height due to urbanization in the LU-EGIS case was higher (the differences of up to $0.1^{\circ}C$ and 36 m, respectively) than those in the LU-USGS case, whereas the wind speed (up to 0.3 $ms^{-1}$) in the former was lower than that in the latter at 1500 LST. The increase in surface temperature due to urbanization in the GSA (especially, the southern parts of Seoul) was led to the strong convergence of air masses, causing the early sea breeze and its rapid propagation to inland locations. In addition, the vertical mixing motion in the extended urban areas for the LU-EGIS case was predicted to be stronger than that for the LU-USGS case and vice versa for the original urban areas.

• Journal of Life Science
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• v.17 no.8 s.88
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• pp.1082-1089
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• 2007

Serological anlysis of recombinant cDNA expression libraries (SEREX) has led to identification of several categories of new antigens recognized by the immune system of cancer patients, which are referred to as the cancer immunome. We analyzed normal testis cDNA expression libraries with serumobtained from non-small lung cancer patient and isolated 40 distinct antigen designated KP-LuT-1 through KP-LuT-40. Among these antigens 20 antigens were previously identified by SEREX analysis of other tumor types, and 20 out of 40 antigens (50%) did not match entries in Cancer Immunome Database and were considered newly identified antigens. Sequencing analysis showed that the anti-gens comprised 26 functional known proteins and 14 noble/uncharacterized gene products. Of these, the hypothetical protein KP-LuT-6 was shown tissue-restricted. RT-PCR showed it to be expressed strongly only in normal testis. In addition to normal tissues-restricted expression, KP-LuT-6 mRNA was detected in lung tumor samples(3/l0), stomach tumor samples(3/l0), and breast tumor samples(l/5), whereas not detected in colon tumor samples(O/I2). These data suggest that KP-LuT-6 is a cancer/testis (CT)-like antigen as a potential target for cancer immunotherapies.

• The Journal of Advanced Prosthodontics
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• v.10 no.1
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• pp.32-42
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• 2018

PURPOSE. The purpose of this study was to derive and compare the inherent color (hue angle, chroma), translucency ($TP_{SCI}$), surface gloss (${\Delta}E^*_{SCE-SCI}$), and surface roughness ($R_a$) amongst selected shades and brands of three hybrid CAD/CAM blocks [GC Cerasmart (CS); Lava Ultimate (LU); Vita Enamic (VE)]. MATERIALS AND METHODS. The specimens (N = 225) were prepared into square-shaped ($12{\times}12mm^2$) with different thicknesses and shades. The measurements of color, translucency, and surface gloss were performed by a reflection spectrophotometer. The surface roughness and surface topography were assessed by white light interferometry. RESULTS. Results revealed that hue and chroma values were influenced by the material type, material shade, and material thickness (P < .001). The order of hue angle amongst the materials was LU > CS > VE, whereas the order of chroma was VE > CS > LU. $TP_{SCI}$ results demonstrated a significant difference in terms of material types and material thicknesses ($P{\leq}.001$). $TP_{SCI}$ values of the tested materials were ordered as LU > CS > VE. ${\Delta}E^*_{SCE-SCI}$ and $R_a$ results were significantly varied amongst the materials (P < .001) and amongst the shades (P < .05). The order of ${\Delta}E^*_{SCE-SCI}$ amongst the materials were as follows $LU>VE{\geq}CS$, whereas the order of $R_a$ was $CS{\geq}VE>LU$. CONCLUSION. Nano-ceramic and polymer-infiltrated-feldspathic ceramic-network CAD/CAM materials exhibited different optical, inherent color and surface parameters.

• Journal of Radiopharmaceuticals and Molecular Probes
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• v.9 no.1
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• pp.17-21
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• 2023

In this study, we evaluated the targeting of prostate cancer (PCa) using [¹⁸F]Florastamin in non-clinical study, for the purpose of therapeutic monitoring of [¹⁷⁷Lu]Ludotadipep, a therapeutic radiopharmaceutical for PCa, [¹⁸F]Florastamin/[¹⁷⁷Lu]Ludotadipep was co-administered to a single-individual prostate tumor bearing mouse model, mimicking clinical condition. Considering the difference in half-life of the two isotopes (¹⁸F or ¹⁷⁷Lu), image scan of whole-body autoradiography was performed at 24 or 48 h after preparation of frozen section, respectively. Then, it was confirmed whether they showed the same targeting efficiency for the area of tumor. A tumor xenograft model was prepared using PSMA-overexpressing PC3-PIP prostate cancer cells. [¹⁸F]Florastamin [111 MBq (3 mCi) in 100 µL]/¹⁷⁷Lu]Ludotadipep [3.7 MBq (100 µCi) in 100 µL] was co-administered through the tail vein, and 2 hours after administration, the mice were frozen, and after freezing for 24 hours, whole-body cryosection was performed at 24 h after freezing. Image scanning using cryosection was performed after 24 or 48 hours after freezing, respectively. In the scan image after 24 hours, tumor uptake of [¹⁸F] Florastamin/[¹⁷⁷Lu]Ludotadipep were simultaneously observed specific uptake in the tumor. In the scan image after 48 hours in the same section, signal of ¹⁸F was lost by decay of radioisotope, and specific uptake image for [¹⁷⁷Lu]Ludotadipep was observed in the tumor. Uptake of [¹⁷⁷Lu]Ludotadipep was specific to the same tumor region where [¹⁸F]Florastamin/[¹⁷⁷Lu]Ludotadipep was uptake. These results suggested that [¹⁸F]Florastamin showed the same tumor uptake efficiency to PCa as [¹⁷⁷Lu]Ludotadipep, and effective therapeutic monitoring is expected to be enable using [¹⁸F]Florastamin during [¹⁷⁷Lu]Ludotadipep therapy for PCa.

• Electronics and Telecommunications Trends
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• v.5 no.4
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• pp.120-133
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• 1990

APPC는 프로그램과 프로그램 사이의 통신을 위해 1982년 IBM에 의해 소개되었다. APPC의 구조적인 기초는 logical unit 6.2이다. 두 사용자가 서로 통신을 하려면 먼저 LU 사이의 세션(session)이 이루어져야 한다. LU 6.2에서의 기본은 conversation 개념이다. conversation은 통신하는 두 프로그램 사이의 연결로 두개의 통신하는 프로그램을 대표하는 두 LU 사이의 세션을 이용한다. conversation은 세션의 serial time slice이다.

• Kyungpook Mathematical Journal
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• v.52 no.4
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• pp.359-373
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• 2012

The block LU factorization is used to solve the coupled Stokes equations arisen from an optimal control problem subject to Stokes equations. The convergence of the spectral element solution is proved. Some numerical evidences are provided for the model coupled Stokes equations. Moreover, as an application, this algorithm is performed for an optimal control problem.