• Title/Summary/Keyword: LS-1

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Segmental Liver Stiffness Evaluated with Magnetic Resonance Elastography Is Responsive to Endovascular Intervention in Patients with Budd-Chiari Syndrome

  • Peng Xu;Lulu Lyu;HaitaoGe;Muhammad Umair Sami;Panpan Liu;Chunfeng Hu;Kai Xu
    • Korean Journal of Radiology
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    • v.20 no.5
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    • pp.773-780
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    • 2019
  • Objective: To assess segmental liver stiffness (LS) with MRI before and after endovascular intervention in patients with Budd-Chiari syndrome (BCS). Materials and Methods: Twenty-three patients (13 males and 10 females; mean age, 42.6 ± 12.6 years; age range, 31-56 years) with BCS as a primary liver disease were recruited for this study. Two consecutive magnetic resonance elastography (MRE) examinations were performed before the endovascular treatment. Fifteen patients who underwent endovascular intervention treatment also had follow-up MRE scans within three days after the procedure. LS was measured in three liver segments: the right posterior, right anterior, and left medial segments. Inter-reader and inter-exam repeatability were analyzed with intraclass correlation coefficients (ICCs) and Bland-Altman analysis. Segmental LS and clinical characteristics before and after the intervention were also compared. Results: Within three days of the endovascular intervention, all three segmental LS values decreased: LS of the right posterior segment = 7.23 ± 0.88 kPa (before) vs. 4.94 ± 0.84 kPa (after), LS of the right anterior segment = 7.30 ± 1.06 kPa (before) vs. 4.77 ± 0.85 kPa (after), and LS of the left medial segment = 7.22 ± 0.87 kPa (before) vs. 4.87 ± 0.72 kPa (after) (all p = 0.001). There was a significant correlation between LS changes and venous pressure gradient changes before and after treatments (r = 0.651, p = 0.009). The clinical manifestations of all 15 patients significantly improved after therapy. The MRE repeatability was excellent, with insignificant variations (inter-reader, ICC = 0.839-0.943: inter-examination, ICC = 0.765-0.869). Bland-Altman analysis confirmed excellent agreement (limits of agreement, 13.4-19.4%). Conclusion: Segmental LS measured by MRE is a promising repeatable quantitative biomarker for monitoring the treatment response to minimally invasive endovascular intervention in patients with BCS.

Electrical Properties on Kraft Insulating Paper used as HVDC Cable (HVDC용 크라프트 절연지의 전기적 특성 평가)

  • Youn, B.H.;Lee, S.J.;Kim, J.N.;Kim, D.W.;Jeon, S.I.
    • Proceedings of the KIEE Conference
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    • 2005.07c
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    • pp.2250-2252
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    • 2005
  • 본 논문은 HVDC용 크라프트 절연지의 기본 전기적 특성평가를 목적으로 온도별 역률의 변화, 절연저항 및 임펄스 절연파괴강도 등을 측정한 결과이다. 온도에 따른 크라프트 절연지의 역률은 $50{\sim}70^{\circ}C$에서 최소 값을 나타내었으며, 밀도가 낮은 시료일수록 낮은 역률을 나타내었다. 하지만, 임펄스 절연파괴 강도는 밀도가 낮을수록 저하되는 특성을 나타내어 적절한 밀도의 선정이 필요하다는 사실을 알았다. 또한, 온도 및 인가 전계에 따른 절연저항을 측정하여 크라프트 절연지의 온도상수 및 전계상수를 측정한 결과, 온도상수 ${\alpha}$$0.09{\sim}0.1^{\circ}C^{-1}$, 전계상수는 약 1.5을 얻었다. 이는 HVDC용 케이블의 설계 시 절연체의 전계분포 및 두께 산정에 기본적인 데이터를 제공할 수 있다.

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Nuclear LS-Energy Matrix Elements with the Harmonic Oscillator Shell Model Wave Functions for the Configurations ($I_1$$I_{1+1}$$I_1$$I_{1+1}$) and Sum Rules (조화 단진동자 파동함수를 쓴 원자핵의 LS에너지 행열요소 합법칙)

  • Chung-hum Kim;Soon-Kwon Nam
    • Nuclear Engineering and Technology
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    • v.14 no.1
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    • pp.22-40
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    • 1982
  • The nuclear LS-energy matrix elements have been calculated with the harmonic oscillator shell model wave functions for the configurations ( $l_{i}$ $l_{i+1}$$l_{i}$ $l_{i+1}$) where 1$_1$= $l_{s}$ , $l_2$=lp, $l_3$=ld, 2s, $l_4$=1f, 2p, $l_{5}$ =1g, 2d, 3s. The resulting matrix elements are expressed in terms of both Talmi integrals $I_1$ and Slater integrals $F^{k}$ . In addition to this various sum rules are derived and applied to check the results of the calculations.ons.

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Two-Dimensional-Shear Wave Elastography with a Propagation Map: Prospective Evaluation of Liver Fibrosis Using Histopathology as the Reference Standard

  • Dong Ho Lee;Eun Sun Lee;Jae Young Lee;Jae Seok Bae;Haeryoung Kim;Kyung Bun Lee;Su Jong Yu;Eun Ju Cho;Jeong-Hoon Lee;Young Youn Cho;Joon Koo Han;Byung Ihn Choi
    • Korean Journal of Radiology
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    • v.21 no.12
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    • pp.1317-1325
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    • 2020
  • Objective: The aim of this study was to prospectively evaluate whether liver stiffness (LS) assessments, obtained by two-dimensional (2D)-shear wave elastography (SWE) with a propagation map, can evaluate liver fibrosis stage using histopathology as the reference standard. Materials and Methods: We prospectively enrolled 123 patients who had undergone percutaneous liver biopsy from two tertiary referral hospitals. All patients underwent 2D-SWE examination prior to biopsy, and LS values (kilopascal [kPa]) were obtained. On histopathologic examination, fibrosis stage (F0-F4) and necroinflammatory activity grade (A0-A4) were assessed. Multivariate linear regression analysis was performed to determine the significant factors affecting the LS value. The diagnostic performance of the LS value for staging fibrosis was assessed using receiver operating characteristic (ROC) analysis, and the optimal cut-off value was determined by the Youden index. Results: Reliable measurements of LS values were obtained in 114 patients (92.7%, 114/123). LS values obtained from 2D-SWE with the propagation map positively correlated with the progression of liver fibrosis reported from histopathology (p < 0.001). According to the multivariate linear regression analysis, fibrosis stage was the only factor significantly associated with LS (p < 0.001). The area under the ROC curve of LS from 2D-SWE with the propagation map was 0.773, 0.865, 0.946, and 0.950 for detecting F ≥ 1, F ≥ 2, F ≥ 3, and F = 4, respectively. The optimal cut-off LS values were 5.4, 7.8, 9.4, and 12.2 kPa for F ≥ 1, F ≥ 2, F ≥ 3, and F = 4, respectively. The corresponding sensitivity and specificity of the LS value for detecting cirrhosis were 90.9% and 88.4%, respectively. Conclusion: The LS value obtained from 2D-SWE with a propagation map provides excellent diagnostic performance in evaluating liver fibrosis stage, determined by histopathology.

A Study of Japan FRT Grid Interconnection Code Based JEAC 9701-2012 (JEAC 9701-2012 기반 일본 FRT 계통연계 규정에 대한 고찰)

  • Myung, Hong-Jae;Kim, Young-Min;Kim, Hee-Jung;Lee, Il-Yong;Do, Won-Seok
    • Proceedings of the KIEE Conference
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    • 2015.07a
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    • pp.1078-1079
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    • 2015
  • 동일본 대지진 이후로 일본은 원자력 발전 가동을 점차 중단시켜 가고 있으며 이에 따라 신재생에너지 발전 비중은 높아지고 있다. 이러한 신재생 에너지원의 확대는 계통의 입장에서 외란의 요소로 작용할 수 있으므로 각 전력회사들은 계통 보호 협조에 관한 규정을 엄격히 적용해 가는 추세이다. 본 논문에서는 일본형 대용량 계통연계형 태양광 인버터들이 가져야 할 기능 중 계통보호 협조에 관한 FRT 기능에 대하여 일본 계통연계 규정인 JEAC 9701-2012[1] 를 기반으로 알아보고 이 규정이 적용되어 개발 된 LS산전의 250/500kW 태양광 PCU를 소개하고자 한다.

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Isolation of Bombesin-Like Substances from the Skin of the Frog, Bombina orientalis: Its Molecular Heterogeneity and Biological Activity (한국에 서식하는 무당개구리의 피부에서 추출된 Bombesin 유사물질의 분자적 이질성 및 생물학적 활성)

  • Park, Hyoung-Jin;Lee, Yun-Lyul;Kwon, Hyeok-Yil;Shin, Won-Im;Suh, Sang-Won
    • The Korean Journal of Physiology
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    • v.23 no.1
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    • pp.79-87
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    • 1989
  • Molecular property as well as biological activities of bombesin-like substance (BBS-LS) isolated from the skin of B. orientalis in Korea was compared with those of synthetic BBS-14. BBS-LS in the crude extract was applied on a Sephadex G-50, superfine column $(1.6{\times}112\;cm)$. On chromatogram, the first peak (3.5% of BBS-LS) was found ahead of synthetic GRP-27, and the second peak (rest) between synthetic GRP-27 and synthetic BBS-14. The main form of BBS-LS was successfully purified by using a column of alkaline alumina followed by sequential gel-filtrations on a column of Sephadex G-10, fine and a column of Sephadex G-50, superfine. Chromatographic analysis of the purified BBS-LS using a column of Sephadex G-50, superfine and reversed phase HPLC revealed that the main form of BBS-LS in the skin of B. orientalis could be distinctly different from either BBS-14 or GRP-27 in molecular size. The purified BBS-LS exerted biological activities quite identical to those of synthetic BBS-14. The results of the present investigation indicate that the skin of B. orientalis contains BBS-LS composed of two distinct forms. The main form of BBS-LS purified in the present study is heterogenous to both synthetic BBS-14 and GRP-27 in molecular size but identical to BBS in biological activities.

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Micellar Catalysis on the Hydrolysis of the Fungicidal N-[1-(benzotriazol-1-yl)benzyl]aniline (항균성, N-[1-(benzotriazol-1-yl)benzyl]aniline의 가수분해 반응에 미치는 미셀 촉매효과)

  • Sung, N.D.;Park, C.K.;Lim, C.W.
    • Applied Biological Chemistry
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    • v.37 no.3
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    • pp.189-193
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    • 1994
  • The hydrolysis of fungicidal N-[1-(benzotriazol-1-yl)benzyl]aniline (BBA) molecule in the presence of cationic cetyltrimethylammonium bromide (CTABr) and anionic sodium laurylsulfate (NaLs) micellar solutions has been studied kinetically. The Micellar catalysis effect shows that the rate is slightly accelerated by the addition of the anionic NaLs at high pH and the binding constant (Ks) is $1.45{\times}10^4M^{-1}$. This result presumably is due to the electrostatic stabilization by the anionic micelle of the developing carbocation in the transition state rather than the hydrophobic character (${\pi}$: 4.93) of (BBA).

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Antioxidant Compounds and Antioxidant Activities of Different Varieties of Foxtail Millet and Proso Millet according to Cultivation Time (품종 및 재배시기에 따른 조와 기장의 항산화성분 및 항산화활성)

  • Woo, Koan-Sik;Lee, Jae-Saeng;Ko, Jee-Yeon;Song, Seuk-Bo;Seo, Hye-In;Seo, Myung-Chul;Oh, Byeong-Geun;Kwak, Do-Yeon;Nam, Min-Hee;Oh, In-Seok;Jeong, Heon-Sang
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.41 no.3
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    • pp.302-309
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    • 2012
  • Effects of cultivation time on the antioxidant contents and activities of foxtail millet and proso millet were determined. The cultivation times were early-season (ES), normal-season (NS), and late-season (LS), and the cultivated varieties were Hwanggeum-cho (HGC), Cheongcha-cho (CCC), Samdamae (SDM), Gyeongkwan 1 (GK 1), Gyeongkwan 2 (GK 2), Ganghae-cho (GHC), Hwanggeum-gijang (HGG), Manhongchal-gijang (MHCG), Byeoruk-gijang (BRG), Norangchal-gijang (NRG), and Whin-gijang (WG). The total polyphenol, flavonoid, tannin content, and DPPH and ABTS radical scavenging activities of the methanolic extracts of foxtail millet and proso millet showed significant differences according to cultivation variety and time. The highest total polyphenol content of foxtail millet was 29.33 mg of gallic acid equivalent (GAE)/g of sample in GK 1 at LS, whereas that of proso millet was 23.48 mg of GAE/g of sample in BRG at LS. The highest total flavonoid content of foxtail millet was 2.12 mg of catechin equivalent (CE)/g of sample in CCC at ES, whereas that of proso millet was 4.49 mg of CE/g of sample in BRG at LS. The highest total tannin content of foxtail millet was 14.07 mg of tannic acid equivalent (TAE)/g of sample in SDM at LS, whereas that of proso millet was 15.59 mg of TAE/g of sample in BRG at LS. The highest DPPH radical scavenging activity of foxtail millet was 7.71 mg of TE/g of sample in CCC at NS, whereas that of proso millet was 12.66 mg of TE/g of sample in BRG at LS. The highest ABTS radical scavenging activity of foxtail millet was 8.05 mg of TE/g of sample in GK 1 at LS, whereas that of proso millet was 34.46 mg of TE/g of sample in BRG at LS. Generally, HGC, GK 1, and GHC had more beneficial effects at LS than ES or NS, whereas CCC, SDM, and GK 2 had more beneficial effects at NS than ES or LS, and proso millet had more beneficial effects at LS than ES or NS.

A Development of JPEG-LS Platform for Mirco Display Environment in AR/VR Device. (AR/VR 마이크로 디스플레이 환경을 고려한 JPEG-LS 플랫폼 개발)

  • Park, Hyun-Moon;Jang, Young-Jong;Kim, Byung-Soo;Hwang, Tae-Ho
    • The Journal of the Korea institute of electronic communication sciences
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    • v.14 no.2
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    • pp.417-424
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    • 2019
  • This paper presents the design of a JPEG-LS codec for lossless image compression from AR/VR device. The proposed JPEG-LS(: LosSless) codec is mainly composed of a context modeling block, a context update block, a pixel prediction block, a prediction error coding block, a data packetizer block, and a memory block. All operations are organized in a fully pipelined architecture for real time image processing and the LOCO-I compression algorithm using improved 2D approach to compliant with the SBT coding. Compared with a similar study in JPEG-LS, the Block-RAM size of proposed STB-FLC architecture is reduced to 1/3 compact and the parallel design of the predication block could improved the processing speed.

수출형 소 용량 태양광 인버터 개발

  • Lee, Il-yong;Kim, Sung-Hwan;Park, Ju-Hyun;Lee, Seung-Goo
    • Proceedings of the KIPE Conference
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    • 2013.11a
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    • pp.121-122
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    • 2013
  • 본 논문에서는 수출형 소 용량 태양광 인버터를 설계, 제작하였으며, 실제 제품을 제작하였다. 해당 제품은 VDE-AR-N_4105 및 VDE V 0126-1-1규정에 준하는 무변압기 방식 태양광 인버터로서 안정적이며 신뢰성 있는 동작을 할 수 있도록 절연레벨, 누설전류 및 기타 계통의 안정성 판단을 2개의 CPU에서 동시에 감시하도록 설계하였다. 또한 높은 IP등급을 만족하도록 설계되어 실외에서도 안정적이고 신뢰성 있는 동작을 할 수 있도록 설계하였다.

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