• Tuberculosis and Respiratory Diseases
• /
• v.49 no.4
• /
• pp.466-473
• /
• 2000

Background : Patients with locally advanced non-small cell lung cancer are often treated with radiation alone or in combination with chemotherapy. Both modalities have a potentially damaging effect on pulmonary function. In order to examine changes in the cardiopulmonary exercise function of patients with locally advanced non-small cell lung cancer before and after conventional radiotherapy, we conducted a prospective study involving patients with such cancer, that had received radiation therapy. Method : Resting pulmonary function test, thoracic radiographic finding and cardiopulmonary exercise test(CPET) were assessed prior to and 4 weeks following radiation therapy in 11 male patients with locally advanced non-small cell lung cancer. Patient with endobronchial mass were excluded. Results : The forces vital capacity (FVC), forced expiratory volume in 1 second ($FEV_1$ and maximal voluntary ventilation (MVV) did not decreased between before and 4 weeks after radiation but the diffusing capacity (DLCO) had decreased by 11% 4 weeks after radiation, which was not statistically significant. No changes in maximal oxygen consumption ($VO_2$max), carbon dioxide production ($VCO_2$), exercise time and work load were attributed to radiation therapy. Follow up cardiopulmonary exercise testing revealed unchanged cardiovascular function, ventilatory function and gas exchange. No difference in cardiopulmonary exercise test performance was observed between pre- and post-radiation. Conclusion : Cardiopulmonary exercise function did not decrease within the short-term after the radiation of patients with locally advanced non-small cell lung cancer.

• Journal of the Korea Institute of Information and Communication Engineering
• /
• v.17 no.10
• /
• pp.2359-2368
• /
• 2013

In this paper, an IRD (internal read data) circuit preventing the reentry into the read mode while keeping the read-out DOUT datum at power-up even if noise such as glitches occurs at signal ports such as an input signal port RD (read) when a power IC is on, is proposed. Also, a pulsed WL (word line) driving method is used to prevent a DC current of several tens of micro amperes from flowing into the read transistor of a differential paired eFuse OTP cell. Thus, reliability is secured by preventing non-blown eFuse links from being blown by the EM (electro-migration). Furthermore, a compared output between a programmed datum and a read-out datum is outputted to the PFb (pass fail bar) pin while performing a sensing margin test with a variable pull-up load in consideration of resistance variation of a programmed eFuse in the program-verify-read mode. The layout size of the 8-bit eFuse OTP IP with a $0.18{\mu}m$ process is $189.625{\mu}m{\times}138.850{\mu}m(=0.0263mm^2)$.

• Proceedings of the Korea Contents Association Conference
• /
• 2007.11a
• /
• pp.135-139
• /
• 2007

Recently Data Centric Storage (DCS) schemes are variously studied for several applications (e.g. natural environment investigation, military application systems and environmental changes monitoring). In DCS scheme, data is stored at nodes within the network by name. There are several drawbacks in the existing schemes. The first is the inefficiency of the range query processing on not considered the locality of store point. the second is the non-homogeneity of store load of each sensors in case of the sensor distribution density is non-uniformed. In this paper, we propose a novel data centric storage scheme with the sensor distribution density which satisfied with the locality of data store location. This scheme divides whole sensor network area using grid and distributes the density bit map witch consist of the sensor density information of each cell. sensors use the density bit map for storing and searching the data. We evaluate our scheme with existing schemes. As a result, we show improved load balancing and more efficient range query processing than existing schemes in environment which sensors are distributed non-uniform.

• Journal of the Korean Geotechnical Society
• /
• v.19 no.6
• /
• pp.387-395
• /
• 2003

Model tests were conducted to study the behavior of the piled raft foundation system on sands. Especially in this study, the method using the triaxial compression apparatus was devised and used to apply the confining pressure which is considered difficult in the existing model test on the soil. Steel rods (6mm dia.) and aluminum plates (8mm thickness, 50mm dia.) were used to simulate piles and rafts respectively. Jumunjin standard sands were used to ensure the homogeneity of the sample. After the sample with the piled raft model was laid inside the triaxial cell, the confining pressure was applied and then the compressive force was applied. The increase and/or decrease ratio of the bearing capacity, the load distribution ratio between raft and piles and the effect of settlements decrease depending on the confining pressure, the number of piles and the length of piles were analyzed and the bearing capacity and skin friction of the pile was calculated. By the results of these experiments, the bearing capacity increased and the settlement decreased with this piled raft foundation system. Especially the effect was larger with the increase of the number of piles than with the increase of length of piles. Hereafter, the study of the load transfer mechanism of piles under confining pressure would be made possible using these small model tester like triaxial compression apparatus.

• Journal of the Korean Institute of Intelligent Systems
• /
• v.20 no.1
• /
• pp.81-87
• /
• 2010

The coverage ability is one of essential techniques for the Robotic Vacuum Cleaner (RVC). Most of the RVCs rely on random or regular pattern movement to cover a target space due to the technical difficulties to implement localization and map and constraints of hardwares such as controller and sensors. In this paper, we consider two main issues which are low computational load and using sensors with very limited sensing capabilities. First, in our approach, computing procedures to build map and detect the RVC's position are minimized by simplifying data obtained from sensors. To reduce computational load, it needs simply presenting an environment with objects of various shapes. Another isuue mentioned above is regarded as one of the most important problems in our approach, because we consider that many RVCs use low-cost sensor systems such as an infrared sensor or ultrasonic sensor with limited capabilities in limited range, detection uncertainty, measurement noise, etc. Methods presented in this paper are able to apply to general RVCs equipped with these sensors. By both simulation and real experiment, we evaluate our method and verify that the proposed method guarantees a complete coverage.

• Journal of Wetlands Research
• /
• v.18 no.4
• /
• pp.424-431
• /
• 2016

LID facilities like bio-retention cells is applied to manage stormwater. LID concept becomes an important part in stormwater management, and the clear understanding of hydrologic performance and hydrologic impact on the corresponding catchment has been needed. In this study, the application of flow duration curves as design strategy is investigated. Bio-retention cells like many LID facilities are installed to reproduce natural hydrologic processes. In this study, the attempt to determine the size of a bio-retention cell is carried out to satisfy the flow duration criteria. From the results, it is shown that "5 mm * the area of a target catchment" which is the current facility design capacity is valid for the drainage area with 20-30% impervious rate. In the 100% impervious catchment where LID facilities are typically installed, the design capacity to intercept stormwater of approximately 47 mm depth is required to reproduce natural flow duration curves. This means that about 11% of the target catchment area should be allocated as a bio-retention cell. However, the criteria of the design capacity and facility surface area should be set at the possible implementation conditions in reality, and site-specific hydrologic characteristics of a target catchment should be considered.

• Transactions of the Korean Society of Mechanical Engineers B
• /
• v.34 no.6
• /
• pp.643-648
• /
• 2010

Portable fuel cells are commonly operated in the dead-end mode because of such as high fuel utilization. However, the performance of such systems deteriorates continuously with an increase in the amount of by-products such as water vapor and nitrogen. In this study, to verify the effect of water vapor on Proton Exchange Membrane Fuel Cells (PEMFCs), constant-load experiments were carried out for a current density of 600 mA/cm2 and a voltage of 0.4 V, respectively. The performance of the cell was more stable under constant voltage conditions than under constant current density conditions. Condensed water accumulated in the anode channel near the cell outlet. The experimental results show how the relative humidity (RH = 0.15, 0.4 and 0.75) of air at the cathode side affect the performance of PEMFCs with dead-end anode. At RH values higher than 0.15, the mean power density increased by up to 51% and the mean purge duration decreased by up to 25% compared to the corresponding initial values.

• Journal of the Institute of Electronics Engineers of Korea TC
• /
• v.37 no.1
• /
• pp.12-22
• /
• 2000

This paper presents the window-based permit distribution scheme for efficient medium access control to support multiclass traffic in APON(ATM over passive optical network). The proposed MAC protocol considers the characteristics of QoS(Quality of Service) for various traffic classes. A periodic RAU(request access unit) in upstream direction, includes dedicative request fields for each traffic category within the request slot. The transmission of upstream cell is permitted by the proposed window-based spacing scheme which distributes the requested traffic into several segments in the unit of one spacing window. The delay sensitive traffic source such as CBR or VBR with the stringent requirements on CDV and delay, is allocated prior to any other class. In order to reduce the CDV, so that the permit arrival rate close to the cell arrival rate, Running-Window algorithm is applied to permit distribution processing for these classes. The ABR traffic, which has not-strict CDV or delay criteria, is allocated flexibly to the residual bandwidth in FIFO manner. UBR traffic is allocated with the lowest priority for the remaining capacity. The performance of proposed protocol is evaluated in terms of transfer delay and 1-point CDV according to various offered load. The simulation results show that our protocol has the prominent improvement on CDV and delay performance with compared to the previous protocol.

• Journal of the Korean Institute of Telematics and Electronics S
• /
• v.36S no.6
• /
• pp.17-29
• /
• 1999

In this paper, the prioritized queueing handoff scheme in CDMA (Code Division Multiple Access) cellular system is proposed. Also, the analytical survey for the proposed scheme is carried out, and the performance of this scheme is compared with that of non prioritized scheme and FIFO (First In First Out) queue scheme by computer simulation. The handoff region is defined as the time between the handoff treshold and the receiver threshold, and it is used for the maximum queue waiting time in the proposed scheme. The handoff and the receiver thresholds are defined as rewpectively: 1) the time that the Pilot Strength Measurement Message in the neighbor in the neighbor cell is received to the BS (Base Station) under the T_ADD threshold; and 2) the time that the T_DROP timer is expired and the Pilot Strength Measurement Message in the current cell is received to the BS under the T_DROP threshold. The performance metrics for analyzing the proposed scheme are : 1) probability of forced termination; 2) probability of call blocking; 3) ratio of carried traffic to total offered load; 4) average queue size; 5) average handoff delay time in queue. The simulation results show that the proposed scheme maintains high performance for handoff requests at a small penalty in total system capacity.

• Asian Pacific Journal of Cancer Prevention
• /
• v.15 no.20
• /
• pp.8693-8698
• /
• 2014

Background: Up-regulation of hsp90 gene expression occurs in numerous cancers such as lung cancer. D,L-lactic-co-glycolic acid-poly ethylene glycol-17-dimethylaminoethylamino-17-demethoxy geldanamycin (PLGA-PEG-17DMAG) complexes and free 17-DMAG may inhibit the expression. The purpose of this study was to examine whether nanocapsulating 17DMAG improves the anti cancer effect over free 17DMAG in the A549 lung cancer cell line. Materials and Methods: Cells were grown in RPMI 1640 supplemented with 10% FBS. Capsulation of 17DMAG is conducted through double emulsion, then the amount of loaded drug was calculated. Other properties of this copolymer were characterized by Fourier transform infrared spectroscopy and H nuclear magnetic resonance spectroscopy. Assessment of drug cytotoxicity on the grown of lung cancer cell line was carried out through MTT assay. After treatment, RNA was extracted and cDNA was synthesized. In order to assess the amount of hsp90 gene expression, real-time PCR was performed. Results: In regard to the amount of the drug load, IC50 was significant decreased in nanocapsulated(NC) 17DMAG in comparison with free 17DMAG. This was confirmed through decrease of HSP90 gene expression by real-time PCR. Conclusions: The results demonstrated that PLGA-PEG-17DMAG complexes can be more effective than free 17DMAG in down-regulating of hsp90 expression by enhancing uptake by cells. Therefore, PLGA-PEG could be a superior carrier for this kind of hydrophobic agent.