• Title/Summary/Keyword: LINK16

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Determining Potential Link between Environmental and Clinical Isolates of Cryptococcus neoformans/Cryptococcus gattii Species Complexes Using Phenotypic and Genotypic Characterisation

  • Kenosi Kebabonye;Mosimanegape Jongman;Daniel Loeto;Sikhulile Moyo;Wonderful Choga;Ishmael Kasvosve
    • Mycobiology
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    • v.51 no.6
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    • pp.452-462
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    • 2023
  • Opportunistic infections due to Cryptococcus neoformans and C. gattii species complexes continue to rise unabated among HIV/AIDS patients, despite improved antifungal therapies. Here, we collected a total of 20 environmental and 25 presumptive clinical cryptococcal isolates from cerebrospinal fluid (CSF) samples of 175 patients enrolled in an ongoing clinical trial Ambition 1 Project (Botswana-Harvard Partnership). Identity confirmation of the isolates was done using MALDI-TOF MS and PCR. We describe the diversity of the isolates by PCR fingerprinting and sequencing (Oxford Nanopore Technology) of the intergenic spacer region. Mating types of the isolates were determined by amplification of the MAT locus. We report an unusual prevalence of 42.1% of C. neoformans × C. deneoformans hybrids Serotype AD (n = 16), followed by 39.5% of C. neoformans Serotype A (n = 15), 5.3% of C. deneoformans, Serotype D (n = 2), 7.9% of C. gattii (n = 3), and 5.3% of C. tetragattii (n = 2) in 38 representative isolates that have been characterized. Mating type-specific PCR performed on 38 representative environmental and clinical isolates revealed that 16 (42.1%) were MATa/MAT𝛼 hybrids, 17 (44.7%) were MAT𝛼, and five (13.2%) possessed MATa mating type. We used conventional and NGS platforms to demonstrate a potential link between environmental and clinical isolates and lay a foundation to further describe mating patterns/history in Botswana.

Power Control Based Call Admission Control Method of the CDMA PCS System

  • 이강원;국광호;최정락
    • Korean Management Science Review
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    • v.16 no.1
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    • pp.39-50
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    • 1999
  • This paper proposes a new call admission control method to enhance the reverse link capacity of a cell with heavy traffic in the CDMA PCS system under the uneven traffic load between cells. Since the capacity of a cell in the CDMA system is restricted by the total interference caused by terminals in the own cell and the adjacent cells, we can enhance the capacity of a cell by reducing the interference from other cells if possible. Our power control method allows that the signal powers received in base stations with heavy traffic be larger than those received in base stations with light traffic in order to make the interference due to other cells in the cells with heavy traffic relatively small. In the previous study, it was assumed that the signal power received by each base station in the CDMA PCS system is same when the call admission control algorithm is implemented. We could show that the reverse link capacity of a cell in the CDMA PCS system can be increased about 20% under our call admission control method.

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Radio Resource Metric Estimation (RRME) Mechanism for Multimedia Service Applications based on a CDMA Communication System

  • Lee Yeon-Woo;Cho Kwang-Moon;Hur Kyeong
    • International Journal of Contents
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    • v.2 no.2
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    • pp.10-16
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    • 2006
  • In this paper, we propose a predictive resource metric region (RMR) based radio resource metric estimation (RRME) mechanism, which utilizes a resource metric mapping function (RMMF), both of which permit efficient inter-working between the physical layer and higher layers for envisaging multimedia service applications over a CDMA communication system platform. The RMR can provide the acceptable resource region where QoS and acceptable link quality can be guaranteed with an achievable resource margin to be utilized in terms of capacity margin, the degree of confidence (DCL) of user, second-order statistics of Eb/Io. With predicted capacity margin and variance, DCL can deliver decision parameters with which an adaptive QoS based admission control can perform well taking capacity and resource availability into account in a dynamic and predictive manner. Combined with advanced techniques such as adaptive modulation or rate control and power control, the proposed mechanism can adjust the conventional stringent link quality information efficiently, and deliver accurate information of the resource availability. Thus, these can guarantee the maximization of resource utilization of multimedia service applications.

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Performance Analysis of Network-based Data Transmission Protocol between Railway Signaling and SCADA Systems (열차제어시스템과 SCADA 장치간 네트워크 기반 데이터 전송 프로토콜의 성능분석)

  • Hwang, Jong-Gyu;Lee, Jae-Ho;Jo, Hyun-Jeong;Lee, Jong-Woo
    • The Transactions of the Korean Institute of Electrical Engineers B
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    • v.55 no.9
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    • pp.485-490
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    • 2006
  • According to the computerization of railway signaling systems, the interface link between the signaling systems has been replaced by the digital communication channel. At the same time, the importance of the communication link is more pronounced than before. In this paper, new Network-based protocol between railway signaling and SCADA (Supervisory Control and Data Acquisition system) has designed and the overview of designed protocol is briefly represented. And also this paper addresses analysis of newly designed train control systems. Fame error rates of the data transmissions are calculated and compared for the two cases that the CTC (Centralized Traffic Control)/SCADA has an extra data transmission error control (CRC16) besides the inherent error control of the Ethernet and that the CTC/SCADA has no extra data transmission error control. With simulation results it has been verified that the additional error control code contributes to lowering the frame error rate. It will be expected to increase the safety, reliability and efficiency of maintenance of the signaling systems by using the designed protocol for railway signaling system.

The Methylenetetrahydrofolate Reductase C677T Polymorphism and Breast Cancer Risk in Asian Populations

  • Rai, Vandana
    • Asian Pacific Journal of Cancer Prevention
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    • v.15 no.14
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    • pp.5853-5860
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    • 2014
  • Background: Methylenetetrahydrofolate (MTHFR) is the key enzyme of the folate metabolic pathway and several studies have pointed to association between the MTHFR C677T polymorphism and breast cancer risk. Although significant association was observed in some studies, in others no clear link could be established. Objective: A meta-analysis of published Asian case control studies was therefor carried out to shed further light on any C677T breast cancer association. Materials and Methods: PubMed, Springer Link, Google Scholar and Elsevier databases were searched for case control studies of associations between MTHFR C677T polymorphism and breast cancer risk. Odds ratios (ORs) with 95% confidence intervals (CIs) were estimated to assess the association. A total of 36 studies including 8,040 cases and 10,008 controls were included in the present meta-analysis. Results: Overall, a significantly elevated breast cancer risk was associated with the T allele and TT genotype in homozygote comparison and dominant genetic models when all studies were pooled into the meta-analysis (T vs C (allele contrast model): OR=1,23, 95%CI=1.13-1.37, p=0.000 ; TT vs CC(homozygote model): OR=1.38, 95%CI=1.16-1.63, p=0.0003; TT+CT vs CC (dominant model): OR=1.12, 95%CI=1.01-1.23, p=0.02). Conclusions: The present meta-analysis strongly suggested a significant association between the MTHFR C677T polymorphism and risk of breast cancer in Asian populations.

Measurement of Carrier-to-Noise due to Sun Interference Effect on C-band for THAICOM 2 Down-link Station at Mung, Khon-kaen

  • A. Waisontia;K. Charouensuk;S.Noppanakeepong;Lee, N. laruji;N. Heammkorn;Y. Moriya
    • Proceedings of the IEEK Conference
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    • 2002.07c
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    • pp.2043-2046
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    • 2002
  • This paper studies on Sun interference effects or Sun outage effects on C-band satellite reception signal for THAICOM2. The THAICOM2 satellite is at 78.5 degree East 〔co-located with THAICOM3〕. The down link station was located in Khon-kaen, longitude 102.83 degree East and latitude 16.43 degree North. The antenna diameter is 4.6 meters for C-band downlink station. Total 9 times of sun interference events were occurred during summer and fall of 2001 and these about 53 minutes altogether. The Maximum CM degradation of the THAICOM2 system was around 11 dB. The Sun interference events of 53 minutes of one year are 0.0122 percents of the C-band contact time when 21 hours of contact time is used f3r broadcasting a day.

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FE Analysis of RC Beams Strengthened with Carbon Fiber Sheet (탄소섬유쉬트로 보강된 RC 보의 유한요소해석)

  • 한상호;이경동
    • Journal of the Computational Structural Engineering Institute of Korea
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    • v.16 no.1
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    • pp.53-58
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    • 2003
  • Carbon fiber sheet has been used to rehabilitate many types of reinforced concrete members with its superior characteristics such as their lightweight, high strength, corrosion resistance, and easy execution. But the failure behavior of reinforced concrete members show a high variation by the bond characteristics between carbon fiber sheet and concrete surface. In this study, a bond stress-slip model, which accounts for changes in bonding behavior between concrete and carbon fiber sheet with some link elements, is proposed. The link elements are used to represent the concrete-carbon fiber sheet interface. To investigate the efficiency of this method, the analytical solutions for the behavior of reinforced concrete beam strengthened with carbon fiber sheet are compared with experimental ones. Results from the proposed model comparatively well agree with the experimental results.

Comparative Study between Two Protection Schemes for DFIG-based Wind Generator Fault Ride Through

  • Okedu, K.E.;Muyeen, S.M.;Takahashi, R.;Tamura, J.
    • Journal of international Conference on Electrical Machines and Systems
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    • v.1 no.1
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    • pp.8-16
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    • 2012
  • Fixed speed wind turbine generators system that uses induction generator as a wind generator has the stability problem similar to a synchronous generator. On the other hand, doubly fed induction generator (DFIG) has the flexibility to control its real and reactive powers independently while being operated in variable speed mode. This paper focuses on a scheme where IG is stabilized by using DFIG during grid fault. In that case, DFIG will be heavily stressed and a remedy should be found out to protect the frequency converter as well as to allow the independent control of real and reactive powers without loosing the synchronism. For that purpose, a crowbar protection switch or DC-link protecting device can be considered. This paper presents a comparative study between two protective schemes, a crowbar circuit connected across the rotor of the DFIG and a protective device connected in the DC-link circuit of the frequency converter. Simulation analysis by using PSCAD/EMTDC shows that both schemes could effectively protect the DFIG, but the latter scheme is superior to the former, because of less circuitry involved.

Performance Analysis of Common Spreading Code CDMA Packet Radio Systems with Multiple Capture Capability (다중캡쳐 특성의 단일확산코드 CDMA 패킷 라디오 시스팀들의 성능 분석)

  • 김동인
    • The Journal of Korean Institute of Communications and Information Sciences
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    • v.16 no.12
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    • pp.1286-1299
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    • 1991
  • In this paper we present a multiple capture model for common spreading code CDMA packet radio systems with star topology. Basic equations for the collision free, header detection. and multiple capture probabilities are derived at the central receiver. Link performances. including the average number of packet captures, allowable number of simultaneous transmission, and system throughput are theoretically evaluated for a hybrid system. combining envelope header detection and differential data detection, Using the Block Oriented Systems Simulator(BOSS), simulations were carried out for the central receivers with envelope or differential geader detection, It is shown that for a threshold approx-imation to the probability of data packet success, the mulyiple capture model significantly improves system throughput.

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Power allocation for full-duplex NOMA relaying based underlay D2D communications

  • Li, Song;Li, Shuo;Sun, Yanjing
    • KSII Transactions on Internet and Information Systems (TIIS)
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    • v.13 no.1
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    • pp.16-33
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    • 2019
  • In this paper, a full-duplex NOMA relaying based underlay device-to-device (D2D) communication scheme is proposed, in which D2D transmitter assists cellular downlink transmission as a full-duplex relay. Specifically, D2D transmitter receives signals from base station and transmits the superposition signals to D2D receiver and cellular user in NOMA scheme simultaneously. Furthermore, we investigate the power allocation under the proposed scheme, aiming to maximize D2D link's achievable transmit rate under cellular link's transmit rate constraint and total power constraint. To tackle the power allocation problem, we first propose a power allocation method based on linear fractional programming. In addition, we derive closed-form expressions of the optimal transmit power for base station and D2D transmitter. Simulation results show that the performance of two solutions matches well and the proposed full-duplex NOMA relaying based underlay D2D communication scheme outperforms existing full-duplex relaying based D2D communication scheme.