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Preparation of High Purity Galacto-Oligosaccharide and Its Prebiotic Activity In Vitro Evaluation (고순도 Galactooligosaccharide 제조 및 유산균 증식 활성)

  • Hong, Ki Bae;Suh, Hyung Joo;Kim, Jae Hwan;Kwon, Hyuk Kon;Park, Chung;Han, Sung Hee
    • The Korean Journal of Food And Nutrition
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    • v.28 no.6
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    • pp.1026-1032
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    • 2015
  • This study attempted to find an efficient method for the preparation of high-purity galactooligosaccharides (HP-GOS) using ${\beta}$-galactosidase and yeast fermentation. GOS prepared using Lactozym 3000L showed the greatest enhancement in total GOS of the six ${\beta}$-galatosidases tested. GOS alone achieved 51% conversion of initial lactose. GOS production was enhanced by fermentation with commercial yeast (Saccharomyces cerevisiae); its concentration reached 71% after 36h fermentation with 8% yeast. Component sugar analysis with HPLC indicated that HP-GOS fermented with S. cerevisiae showed significantly increased levels of 4'/6'-galactosyllactose and total GOS as well as a significantly decreased glucose level. HP-GOS facilitated the growth of Lactobacillus sp. (L. acidophilus and L. casei) and Bifidobacterium sp. (B. longum and B. bifidum). In sum, high-purity GOS has been successfully produced through both an enzymatic process and yeast fermentation. GOS encourages the growth of bacteria such as Lactobacillus and Bifidobacterium that may be beneficial to human gastrointestinal health.

Factors Affecting the Capabilities and Performance of Industry-Academic Cooperation: A Firm-Centered Approach (산학협력 성과에 미치는 영향요인 분석: 기업의 관점을 중심으로)

  • Kong, Jae-Hyung;Kim, Kyoum-Sup;Jang, Hoo-Eun;Heo, Sun-Young;Lee, Jong-Ho
    • Journal of the Economic Geographical Society of Korea
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    • v.23 no.1
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    • pp.82-92
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    • 2020
  • This study attempts to explore the activities and performance of industry-academic cooperation with the perspective of the firm that has not been systematically addressed in the previous research. To do this, a survey of university family companies across the country was conducted to draw factors that influence the competencies of firms and universities on the performance of industry-academic cooperation and to compare differences by region. The main results of the study are as follows. First, it was found that the knowledge and technologies that universities retain and the active participation of companies in the activities of university-academic cooperation were the most important contributors to the corporate achievements in industry-academic cooperation. Second, when divided into the Seoul metropolitan area and non-capital area, it was found that there was a difference in the capabilities and performance of industry-academic cooperation between the two regions. Third, it was found that there were significant differences in the capabilities and performance of industry-academic cooperation in five areas. These findings suggest that industry-academic cooperation projects specialized for each region is necessary to enhance the effectiveness of industry-academic cooperation.

Permeation Flux of Ester Compounds through Hydrophobic Membrane by Pervaporation (투과증발에 의한 Ester 성분의 소수성막의 투과플럭스)

  • Song, Kun-Ho;Lee, Kwang-Rae
    • Membrane Journal
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    • v.26 no.3
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    • pp.197-204
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    • 2016
  • The objective of this work was to investigate the performance of pervaporation process for recovery of ester compounds from model aqueous solutions and how the fluxes of esters and water were affected by changes in feed concentration and temperature. The flux of ethyl acetate (EA), propyl acetate (PA), ethyl propionate (EP), butyl acetate (BA), and ethyl butyrate (EB) increased with an increase in feed concentration from 0.15 wt% to 0.60 wt%, and increased with temperature change from $30^{\circ}C$ to $50^{\circ}C$. The flux of esters (EA, PA, EP, BA, and EB) was in order of (EA) < (PA, EP) < (BA, EB). This result meant that the flux strongly depended on affinity between esters and membrane surface; EA is the least hydrophobic because it has one hydrophobic function group ($-CH_2-$), (PA, EP) have two ($-CH_2-$), and (BA, EB) are the most hydrophobic because these have three ($-CH_2-$). As well as such an influence of hydrophobicity of ester molecules on ester flux, the influence of hydrophobicity of membrane surface on ester flux needs further investigation. With increase in temperature, water flux of aqueous EA, PA, EP, BA, and EB solution increased. However, water flux of aqueous ester solutions did not change appreciably with increase in concentration. This experimental results may be used as fundamental data for pervaporation (PV) to improve the aroma recovery process as an alternative to thermal evaporation and distillation processes.

A Study on the Commercialization of a Blockchain-based Cluster Infection Monitoring System (블록체인 기반의 집단감염 모니터링 시스템의 상용화 연구)

  • Seo, Yong-Mo;Hwang, Jeong-Hoon
    • The Journal of the Korea Contents Association
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    • v.21 no.10
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    • pp.38-47
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    • 2021
  • This study is about a blockchain-based collective quarantine management system and its commercialization model. The configuration of this system includes a biometric information transmission unit that generates biometric information based on measured values generated from wearable devices, a biometric information transmission unit that transmits biometric information generated here from a quarantine management platform, and action information transmitted from the community server. is a system including an action information receiving unit for receiving from the quarantine management platform. In addition, a biometric information receiving unit that collects biometric information from the terminal, an encryption unit that encodes biometric information generated through the biometric information receiving unit based on blockchain encryption technology, and a database of symptoms of infectious diseases to store symptom information and an infection diagnosis database. The generated database includes a location information check unit that receives from the terminal of the user identified as a symptomatic person and determines whether the user has arrived in the community based on the location information confirmation unit and the location of the user after the location is confirmed. It includes a community arrival judgment unit that judges. And, the community server helps the interaction between the generated information. Such a blockchain based collective quarantine management system can help to advance the existing quarantine management system and realize a safer and healthier society.

A Theoretical Study on the Coevolution Strategy of University Innovation Ecosystems (대학 혁신생태계의 공진화 전략에 대한 이론적 고찰)

  • Park, Sang-Kyu
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.21 no.12
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    • pp.268-277
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    • 2020
  • This study emphasizes that the survival strategy of universities should be a co-evolution strategy based on ecological thinking. Therefore, the purpose of the research is to present a theoretical framework for dividing the university innovation ecosystem into four stages and building a co-evolution strategy for each step, as universities play a prominent role in regional innovation ecosystems. Thus, our research method focused on literature research, and the theoretical framework for the university innovation ecosystem used Moore's Enterprise Ecosystem Model (1996). The university's ecological innovation strategy is divided into four stages of development, and a step-by-step co-evolution strategy is presented. Findings are summarized as follows. The pioneering stage involves the creation of values of the university-led innovation ecosystem. The expansion stage focuses on the establishment of critical mass. The authority stage covers maintaining authority and bargaining power. The renewal stage features continuous performance improvement. In particular, this theoretical model of the university-regional innovation ecosystem is meaningful in that it provides a theoretical basis for enhancing the effectiveness of government financial support projects, and for individual universities, it provides a framework for strategies suitable for their ecosystem building process.