• Asian Pacific Journal of Cancer Prevention
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• 제13권7호
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• pp.3417-3422
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• 2012

Objective: Non-homologous end joining (NHEJ) is one of the pathways of repair of DNA double-strand breaks. A number of genes involved in NHEJ have been implicated as breast cancer susceptibility genes such as LIG4. However, some studies have generated conflicting results. The aim of this Human Genome Epidemiology (HuGE) review and meta-analysis was to investigate association between LIG4 gene polymorphisms in the NHEJ pathway and breast cancer risk. Methods: Studies focusing on the relationship between LIG4 gene polymorphisms and susceptibility to breast cancer were selected from the Pubmed, Cochrane library, Embase, Web of Science, Springerlink, CNKI and CBM databases. Data were extracted by two independent reviewers and the meta-analysis was performed with Review Manager Version 5.1.6 and STATA Version 12.0 software, calculating odds ratios (ORs) with 95% confidence intervals (95%CIs). Results: According to the inclusion criteria, we final included seven studies with a total of 10,321 breast cancer cases and 10,160 healthy controls in the meta-analysis. The results showed no association between LIG4 gene polymorphisms (rs1805386 T>C, rs1805389 C>T, rs1805388 C>T and rs2232641 A>G) and breast cancer risk, suggesting that the mutant situation of these SNPs neither increased nor decreased the risk for breast cancer. In the subgroup analysis by Hardy-Weinberg equilibrium (HWE) and ethnicity, we also found no associations between the variants of LIG4 gene and breast cancer risk among HWE, non-HWE, Caucasians, Asians and Africans. Conclusion: This meta-analysis suggests that there is a lack of any association between LIG4 gene polymorphisms and the risk of breast cancer.

• 전기학회논문지
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• 제67권3호
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• pp.406-412
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• 2018

This paper describes the fabrication process of laser induced graphene (LIG) and its transfer method on to a flexible and stretchable PDMS substrate. By irradiating CO2 laser on a polyimide(PI) film surface, a localized high temperature is created, resulting in a three-dimensional porous graphene network structure with good conductivity. This LIG electrode is relatively easy to fabricate and since it is very weak the LIG electrode was transferred to a flexible PDMS substrate to increase the sturdiness as well as possible use in flexible applications. Sheet resistance, thickness, and electrochemical activity of the fabricated in-situ LIG electrodes have been examined and compared with the LIG electrodes after transferring to PDMS elastomer. The properties of the LIG electrodes were also examined depending on the $CO_2$ laser power. As the irradiated laser power increased, the LIG electrode resistance decreases and the LIG electrode thickness increased. At 4.8 W of laser power, the average sheet resistance and thickness of the fabricated LIG electrodes were approximately $31.7{\Omega}/{\Box}$ and $62.67{\mu}m$, respectively. Moreover, the electrochemical activity of the fabricated LIG electrode at 4.8 W of laser power showed a high oxidation current of $28.2{\mu}A$ after transferring to PDMS.

• 한국군사과학기술학회지
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• 제24권1호
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• pp.107-114
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• 2021

By analyzing the voice communication performance of the existing tactical FM radios, the performance target of the newly developing TICN combat network radio system VHF band tactical voice communication waveform was derived. In addition, a vocoder and modulation method that can satisfy the performance target and additional requirements are presented, and the expected voice communication quality is analyzed.

• 한국소음진동공학회논문집
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• 제25권4호
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• pp.255-265
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• 2015

Shelter system is applying to weapon systems as usage of performing specific mission with arranging several electronic equipments and operators. Recently the electronic equipments is changing from development products to COTS(commecial off-the-shelf) for demonstrating high performance at low cost. As internal operators of shelter system conduct several missions for specific or long time in this present situation, one of the most important element considering the best combat power is internal noise level. Therefore, I desire to analyze the features and foresee multiple noise level with test for conforming whether requirements of design is met or not in this research paper.

• 대한조선학회지
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• 제52권4호
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• pp.37-40
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• 2015

• 정보처리학회지
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• 제30권4호
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• pp.32-41
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• 2023

• 한국항행학회논문지
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• 제28권4호
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• pp.393-399
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• 2024

미래형 항공기체 (AAV; advanced air vehicle)에 탑재될 전자지도 컴퓨터는 고성능, 저중량, 이식성, 모듈화가 요구된다. 전자지도 컴퓨터는 지형, 날씨, 장애물 등의 데이터를 외부 모듈로부터 수신하여 전자지도를 시현 하는 기능을 갖추어야 한다. 이를 위해 Ethernet 인터페이스를 통한 외부 장비와의 통신 기능과 HDMI (high-defintion multimedia Interface), DVI (digital visual interface) 같은 인터페이스를 통해 전자지도 영상 송출 기능을 포함해야 한다. 본 논문에서는 AAV용 전자지도의 기능과 요구사항을 기본적으로 충족하는 하드웨어와 소프트웨어 아키텍처 설계를 제안하였다. 또한, 설계된 전자지도 컴퓨터의 연산 처리 성능을 측정하여 AAV용 전자지도 컴퓨터로서의 적합성을 검증하였다.

• International Journal of Internet, Broadcasting and Communication
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• 제16권1호
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• pp.330-338
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• 2024

In this paper, a Ka-band high-output active phased array antenna device applicable to small radars and seekers was designed, and the improved performance was studied. The radiation device assembly consists of 1x8 arrangements, and the step flared notch antenna type. It shows low active reflection loss characteristics in broadband, and low loss characteristics by applying the air-strip feeding structure, and is designed to enable beam steering up to 45 degrees. The TRM(transmit receive module) output power is more than 2.0W per channel using GaN HPA in the transmitting path, and satisfies more than 25.0 dB gain and less than 6.0 dB noise figure in the receiving path. Accordingly, the Effective Isotropically Radiated Power(EIRP) of the antenna unit shows the performance of 0.00 dB or more and the receive gain-to-noise temperature ratio(G/T) of 0.00 dB/k or more. For demonstration, we have designed aforementioned planar array antenna which consists of 64 radiating elements having a size within 130 mm x 130 mm x 300 mm and weight of less than 4.9 kg..

• 한국군사과학기술학회지
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• 제25권5호
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• pp.530-538
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• 2022

Recently, the R&D of weapon systems has been strengthened in terms of economic cost management throughout the entire life cycle from performance. This study proposes the method for setting the optimal maintenance concept based on RAM-C in weapon system acquisition stage by calculating the operation & maintenance cost as well as reliability, availability, and maintainability. First, we design a simulation model for analysis of weapon system logistic supportability. In addition, information such as weapon system Part Breakdown Structure, operation & maintenance system, cost, and etc for simulation analysis, is applied. Based on the obtained simulation results, the optimal plan is selected among alternatives designed with various maintenance concepts through normalization and weight setting. It is expected to be of technical help in the application of RAM-C in the weapon system acquisition stage.

• International Journal of Internet, Broadcasting and Communication
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• 제15권4호
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• pp.115-127
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• 2023

In this paper, we have undertaken a comprehensive investigation into the current state of anti-drone technology due to the increasing concerns and risks associated with the widespread use of drones. We carefully analyze anti-drone technology, dividing it into three crucial domains: detection, identification, and neutralization methods. This categorization enables us to delve into intricate technical details, highlighting the diverse techniques used to counter evolving drone threats. Additionally, we explore the legal and regulatory aspects of implementing anti-drone technology. Our research also envisions potential directions for advancing and evolving anti-drone tech to ensure its effectiveness in an ever-changing threat environment.