• 제목/요약/키워드: LFT

검색결과 109건 처리시간 0.032초

입원환자 한약투여와 약인성 간손상과의 관계 (Relationship between Herb-Medicine and Liver Damage)

  • 이시형;박정섭;여현수;최유경;전찬용;박종형;김동우
    • 대한한방내과학회지
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    • 제27권3호
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    • pp.572-578
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    • 2006
  • Objectives : This study investigated whether taking herbal medicine over the long-term had any side effects of liver damage. Methods : We checked LFT levels of the 58 admitted patients. Results : When we compared admission LFT levels with discharge LFT levels, we found the levels of AST, ALT and LDH had decreased. This test showed statistically significant decrease. When we compared admission LFT levels with discharge LFT levels, we found the increases of discharge LFT levels fell within the standard deviation. When we compared admission LFT levels with discharge LFT levels, we found the levels of LFT did not increase as much as two standard deviations. Conclusions : According to the above results, taking herbal medicine over a long-term did not have any side effects of drug-induced liver damage.

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연속적으로 시행한 공장 근로자 건강 검진에서 무증상 간기능 검사 이상자의 임상적 특성 (Clinical Characteristics of Factory Wokers with Asymptomatic Liver Function Test Abnormalities in Serial Health Examination)

  • 김강모;김윤준;이광혁;백도명
    • 한국건강관리협회지
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    • 제3권2호
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    • pp.121-136
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    • 2005
  • Background/Aims The liver funtion tests(LFTs), such as aspartate aminotransferase(AST), alanine amino-transferase(ALT), r -glutamyl transferase( r -GT), have been widely used for screening tests but their low positive predictive value can cause many false positive results. To evaluate the clinical usefulness of these tests, we analyzed serial LFT results of single factory workers and compared the risk factor's in groups divided by the serial LFT results. Methods From June 2001 to October 2001, 1223 consecutive healthy workers in a single factory were enrolled and questionnaire, LFT and liver ultrasonography were performed. Previous LFT results were collected from Annual Health Examination Survey. According to the abnormalities in serial LFT, participants were classified into three groups (abnormal-in-both, alternating normal-in-both) and the risk factors were compared among these groups using multiple logistic regression Results The prevalence of LFT abnormality in a single test was 16.8% but, in serial LFT, only 5% of participants showed consistent abnormality. The risk factors for abnormal-in-both group, compared with alternating group, were liver ultrasonography abnormality such as fatty liver(odds ratio, 2.2; p=0.026) and heavy alcohol intake (more than 210g/week) (odds ratio, 7.2;P=0.064). HBsAg was not significant risk factor for any of the three groups. ConclusionIn factory workers with serial LFT abnormality, alcoholic liver disease could be the principal cause of abnormal LFT. Even if HBsAg were positive in patients with abnormal LFT, there is a possibility of another causes for LFT abnormalities such as alcoholic liver disease and nonalcoholic steatosis or steatohepatitis

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선형 행렬부등식과 분해법을 이용한 퍼지제어기 설계 (Design of LFT-Based T-S Fuzzy Controller for Model-Following using LMIs)

  • 손홍엽;이희진;조영완;김은태;박민용
    • 한국지능시스템학회:학술대회논문집
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    • 한국퍼지및지능시스템학회 1998년도 추계학술대회 학술발표 논문집
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    • pp.123-128
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    • 1998
  • This paper proposes design of LFT-based fuzzy controllers for model-following, which are better than the previous input-output linearization controllers, which are not able to follow the model system states and which do not guarantee the stability of all states. The method proposed in this paper provides a LFT-based Takagi-Sugeno(T-S) fuzzy controller with guaranteed stability and model-following via the following steps: First, using LFT(Linear Fractional Transformation) and T-S fuzzy model, controllers, are obtained. Next, error dynamics are obtained for model-following, and errors go to 0(zero). Finally, a T-s fuzzy controller that can stabilizxe the system with the requirement on the control input satisfied is obtained by solving the LMIs with the MATLAB LMI Control Toolbox and a model-following controller is obtained. Simulations are performed for the LFT-based T-S fuzzy controller designed by the proposed method, which show better performance than the results of input-out ut linearization controller.

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한약으로 치료 받은 건선 환자 107명의 안전성 및 유효성에 대한 고찰 (The Safety and Efficacy of Herbal Medicine for 107 Psoriasis Patients: A Retrospective Chart Review)

  • 이병철;최은지
    • 대한한의학회지
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    • 제37권1호
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    • pp.34-40
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    • 2016
  • Objectives: To observe safety and efficacy of herbal medicine for psoriasis patients. Methods: We did retrospective chart review for 107 psoriasis patients who had been treated by herbal medicine for 2 months, and we analyzed the liver function test (LFT) results and Psoriasis Area and Severity Index (PASI) scores of before and after the treatment. Results: The mean LFT and the number of patients with abnormal LFT decreased after the treatments. More than 95% of patients with normal LFT maintained normal results at after the treatment, and only 2.1% and 4.6% patients with normal LFT showed abnormal Glutamic Oxaloacetic Transaminase (GOT) and Glutamic Pyruvic Transaminase (GPT) results at after the treatment. Also, both mean PASI scores for all patients and patients with abnormal LFT before the treatment decreased significantly. Conclusions: This study suggest that herbal medicine may be safe and effective treatment for psoriasis.

LFT소재 특성을 고려한 Door Carrier Plate 변형 해석 (Warpage analysis of a Door Carrier Plate in the injection molding Considering the characteristics of LFT)

  • 유호영;박시환
    • 한국산학기술학회논문지
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    • 제14권8호
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    • pp.3625-3630
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    • 2013
  • 도어 모듈은 모듈화의 대표적인 예로 여러 부품들은 모듈형태로 완성하여 완성차 업체의 원가절감 및 조립시간 단축, 품질 향상 등에 큰 기여를 이루었다. 주요 부품중의 하나인 Door carrier plate는 주로 steel을 이용한 press 성형이 주였으나 최근에는 PP-LFT(유리 장섬유 강화PP)를 사용한 사출 공법을 적용함으로써 형상자유도를 높혀 모듈에 부착되는 많은 종류의 부품들을 통합할 수 있게 되었으며 중량 절감을 이룰 수 있게 되었다. 하지만 사출 성형시 제품의 형상 및 gate위치 설정의 한계성과, LFT의 특성에 의하여 변형이 비교적 심해 일반적으로 시사출 진행 후 보상 가공을 진행하여 조립성을 개선한다. 이러한 사후 수정 공정은 금형의 품질 저하 및 생산원가 상승의 주요인이다. 부분적으로 사출 CAE를 적용하여 warpage정도를 예측하나 그 신뢰성 확보에 어려움을 겪고 있다. 따라서 LFT를 사용하는 Door carrier plate에 대한 해석 신뢰성을 확보할 수 있는 기법으로 hyper-mesh에서 1차 mesh작업 후 moldlfow 자체 tool을 이용하여 mesh의 두께 구현성을 높혔으며, fiber orientation해석을 위하여 ARD-RSC model을 적용하였다.

이산시간 시스템에서 (J,J')-lossless 분해와 $H^{\infty}$ 제어 ((J,J')-lossless factorization and $H^{\infty}$ control in discrete-time systems)

  • 정은태;이재명;박홍배
    • 전자공학회논문지B
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    • 제31B권5호
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    • pp.65-72
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    • 1994
  • 이산시간 시스템에서 선형분수변환(LPT : linear fractional transformation)으로 표현된 $H^{\infty}$ 제어문제를 체인스케터링표현(CSD : chain scattering description)으로 나타내어 (J,J')-ossless 소인수분해를 이용하여 준최적 $H^{\infty}$ 제어문제를 해결하였다. LFT를 CSD형태로 변환하기 위해서는 표준플랜트의 $P_{21}$의 역행렬이 존재하여야 한다. 본 논문에서는 $P_{21}$의 역행렬이 존재하지 않는 4-블럭문제에서도 LFT를 CSD로 변환하는 방법을 제시하고 이렇게 변환된 행렬을 (J,J')-lossless 소인수분해함으로서 모든 준최적 $H^{\infty}$ 제어기를 매개변수화하였다. 또한 제안한 방법은 단지 두개의 리카티 방정식을 풀므로서 이산시간 시스템의 준최적 $H^{\infty}$ 제어문제를 해결할 수 있음을 보였다.

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트레일링 암 생산용 LFT-D 시스템에서의 압축성형 해석 (Compression Molding Analysis of LFT-D System for Vehicle Trailing Arm)

  • 박보규;정진우;정한규;박시우;하동수;최현열
    • 한국기계가공학회지
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    • 제16권6호
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    • pp.133-138
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    • 2017
  • Recently, CFRP composites are widely used as lightweight materials have with excellent mechanical properties and can beare widely used in various fields. In general, thermosetting resins are used for CFRP. However, in recent years, studies have been carried out using thermoplastic resins have been actively carried out to overcome the disadvantages of thermosetting resins. The LFT-D system is a molding method in which a fiber is directly cut to a the desired length while being impregnated with a thermoplastic resin to produce a compound and that is then press-molding molded to form the product. In this paper, before the production of the trailing arm, the compression molding analysis was carried out in order to grasp the problems that may occur during production. Through cCompression molding analysis was applied to calculate of the minimum press pressure and to compare and analysis analyze the molding conditions characteristic required to formfor forming the trailing arm.

LFT-D 시스템을 이용한 탄소 장섬유 열가소성 복합재의 제조 및 인장특성 분석 (Fabrication and Characterization of Carbon Long-Fiber Thermoplastic Composites using the LFT-D System)

  • 신유정;정한규;박시우;박동욱;박열;정진우
    • 한국기계가공학회지
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    • 제16권5호
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    • pp.25-30
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    • 2017
  • Carbon-fiber-reinforced plastic (CFRP) composite materials have been widely used in various industrial fields because the design variables can be adjusted according to the application of the required structure. Thermosetting and thermoplastic resins are used as the base materials of CFRP composites for the lightweight construction of automotive components. Thermoplastics have several advantages such as no curing and recyclability compared to thermosetting resin. In this study, CFRP composites were made using the Long-Fiber Thermoplastic-Direct (LFT-D) process. The LFT-D process includes an in-line production system that directly impregnates a thermoplastic resin, extrudes the composite material, and molds it. This process increases the strength and decreases the molding time. The tensile strength characteristics on the mechanical properties of CFRP were analyzed according to the parameters of LFT-D based on thermoplastics. To analyze the properties of CFRP, the specimens were prepared based on the tensile test standard ASTM 3039 of composite materials.

봉독약침이 장기환자의 LFT와 RFT에 미치는 영향 (An experimental studies on the LFT, RFT of patients in Bee-venom Acupunture)

  • 이병철;천미나;양명복
    • Journal of Acupuncture Research
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    • 제17권2호
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    • pp.11-18
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    • 2000
  • Bee-venom Acupucture has good effect on pain control but We may be anxious about the problem of Liver and Kidneys on many times treated patients. Therefore, In order to analysis the clinical form, We have observed the LFT, RFT of 37 patients who visited Won-Kwang University Kunpo Oriental Medical Hospital and treated Bee Venom therapy over 20 times from March 1999 to February 2000. The results were summarized as follows 1. The distribution of sex was 25 females, 12 males, and the average of patients age was 42.3 years 2. The distribution of disease was degenerative arthritis, HIVD of L-spine, HIVD of C-spine, spinal stenosis, RA, etc. 3. The total treated times is 1464 and the average of treated times is 39.6 times 4. The results of the LFT(AST, ALT) of 37 patients showed that normal impression is occupied 91.9% and abnormal impression is occupied 8.1%. 5. The results of the RFT(BLTN, Creatinine) of 37 patients showed that normal impression is occupied 100%. 6. The results of treatment using BV-acupunture showed that 81.1% achieved above excelent recovery 13.5% achieved above good recovery, 5.4% achieved fair recovery.

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캐비티 내압 측정 및 CAE해석을 통한 Long Fiber Thermoplastic(LFT)의 점도 추정 (Estimation of LFT viscosity from CAE analysis with measuring cavity pressure)

  • 김용현;노승규;김동학
    • 한국산학기술학회:학술대회논문집
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    • 한국산학기술학회 2011년도 추계학술논문집 1부
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    • pp.345-348
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    • 2011
  • 본 논문에서는 LFT와 같은 고점도 수지의 점도를 추정하기 위한 방법을 제시하였다. 실제 사출공정에서의 점도를 추정함으로써 신뢰할 수 있는 점도데이터를 제공하기 위한 방법을 제시 하였다. 우선 금형 내에 캐비티 압력을 측정할 수 있는 시스템을 구성하였고, 이 시스템을 이용해서 실제 사출과정에서 나타나는 압력 변화를 측정하는 것이다. 상용화 된 CAE 프로그램(Moldflow)은 사출공정에서 캐비티 내부를 흐르는 수지의 압력변화를 모사할 수 있다. 만약, CAE D/B에 있는 수지의 점도 데이터가 정확하다고 가정하면, 실험에서 측정한 압력 프로파일과 CAE로부터 계산 된 압력 프로파일이 일치해야 한다. 이것이 실험값과 일치하지 않으면 가정한 값을 CAE D/B에 입력해서 일치할 때까지 반복함으로써 신뢰성 있는 점도를 추정 할 수 있다. 한편, LFT에 대하여 적용하여 최적화 된 점도 데이터도 추정할 수 있었다.

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