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Estimation of Surface Forces in Micro Rough Surface Contacts

  • Kim, Doo-In;Ahn, Hyo-Sok;Choi, Dong-Hoon
    • 한국윤활학회:학술대회논문집
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    • 한국윤활학회 2002년도 proceedings of the second asia international conference on tribology
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    • pp.63-64
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    • 2002
  • In a micro-scale contact, surface forces such as capillary force and van der Waals Interaction significantly Influence the contact between asperities of rough surfaces. Little is, however, known about the variation of these surface forces as a function of chemical property of the surface (hydrophilicity), relative humidity and deformation of asperities In the real area of contact. A better understanding of these surface forces is of great necessity in order to find an optimal solution for reducing friction and adhesion of micro surfaces. We proposed an effective method to analyze capillary and van der Waals forces In nano-scale contact. In this method, Winklerian foundation model was employed to analyze the contact of rough surfaces that were obtained from atomic force microscopy (AFM) height Images. Self-mated contact of diamond-like-carbon (DLC) coatings was analyzed, as an example, by the proposed model. It was shown that the capillary force was significantly influenced by relative humidify and wet angle of the DLC surface. The deformation of asperities to a critical magnitude by external loading led to a considerable increase of both capillary and van der Waals forces.

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대구시 구도심 활성화 방안에 관한 연구 -유휴 학교시설 활용방안을 중심으로- (A Study on Activation Methods of Old Downtown in Daegu -Concentrated on the Practical Use of Unused School Facilities-)

  • 이종국
    • 교육녹색환경연구
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    • 제10권1호
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    • pp.64-73
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    • 2011
  • Jung-gu in Daegu is an old downtown that has led the development of Daegu as a representative center and a commercial area with historicity and placeless. However, an urban center is losing its vitality due to the transfer of city halls and the development of new towns. The downtown area that is still important in a city should lead urban development continuously so that it needs to return its vitality by rehabilitating the weakling urban center. Accordingly this study makes the school which shows drop in the number of students and classes in the school buildings located in Jung-gu, Daegu. Consequently this study figures out a cause for the occurrence of unused school facilities and find a solution as the space for local residents by investigating the facilities of schools, the surroundings, the reality, and the present condition. This study is conducted to examine actual situations of a downtown area that has gone through development and history of Daegu as a center. To this end, it aims to seek for methods to activate the city by relating the practical use of unused school facilities.

Identification of a Protein Interacting with Human Nebulin SH3 Domain by Yeast Two-hybrid Screening

  • Lee, Min-A;Kim, Ji-Hee;Min, Byung-In;Park, Soo-Ho;Ko, Han-Suk;Kim, Chong-Rak
    • 대한의생명과학회지
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    • 제7권2호
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    • pp.59-64
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    • 2001
  • Nebulin is an unusually large actin-binding protein specific to the skeletal muscle of vertebrates. The correlation of nebulin size with thin filament length have led to the suggestion that nebulin acts as a molecular ruler for the length of thin filaments. An SH3 domain occupies the C terminus of nebulin, in the sarcomeric Z-disk and is preceded by a 120-residue stretch containing multiple putative phosphorylation sites. SH3 domain mediates protein-protein interaction involved in the subcellular localization of proteins, cytoskeletal organization and signal transduction. However the binding partner and physiological role of nebulin SH3 domains remains unknown. Using the yeast two-hybrid system, we identified supervillin, an actin-binding protein, as a nebulin SH3 domain-interacting protein. The SH3 domain of nebulin binds to the sequence encoding amino acids 977 to 1335 of supervillin. But the sequence encoding amino acids 977 to 1335 displays weaker binding than the sequence encoding amino acids 977 to 1788.

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SNP Discovery from Transcriptome of Cashmere Goat Skin

  • Wang, Lele;Zhang, Yanjun;Zhao, Meng;Wang, Ruijun;Su, Rui;Li, Jinquan
    • Asian-Australasian Journal of Animal Sciences
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    • 제28권9호
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    • pp.1235-1243
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    • 2015
  • The goat Capra hircus is one of several economically important livestock in China. Advances in molecular genetics have led to the identification of several single nucleotide variation markers associated with genes affecting economic traits. Validation of single nucleotide variations in a whole-transcriptome sequencing is critical for understanding the information of molecular genetics. In this paper, we aim to develop a large amount of convinced single nucleotide polymorphisms (SNPs) for Cashmere goat through transcriptome sequencing. In this study, the transcriptomes of Cashmere goat skin at four stages were measured using RNA-sequencing and 90% to 92% unique-mapped-reads were obtained from total-mapped-reads. A total of 56,231 putative SNPs distributed among 10,057 genes were identified. The average minor allele frequency of total SNPs was 18%. GO and KEGG pathway analysis were conducted to analyze the genes containing SNPs. Our follow up biological validation revealed that 64% of SNPs were true SNPs. Our results show that RNA-sequencing is a fast and efficient method for identification of a large number of SNPs. This work provides significant genetic resources for further research on Cashmere goats, especially for the high density linkage map construction and genome-wide association studies.

아동의 문제행동에 영향을 미치는 위기요인과 보호요인의 이론적 과정모델 (The Effects of Risk Factors and Protective Factors on Children's Problem Behavior: The Theoretical Process Model)

  • 이선경;이재연
    • 아동학회지
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    • 제19권2호
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    • pp.49-64
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    • 1998
  • The theoretical process model was used to study problem behavior of children growing up at-risk. A sample of 339 children living in at-risk families were selected from among 2, 134 children in grades 4, 5, and 6 of five elementary schools in Seoul. The instruments were five risk factor scales and four protective factor scales. The Child Behavior Checklist was also used. The results of the hypothetical model of children at-risk showed that the factor of socioeconomic status led to positive child rearing attitudes in mothers, which is turn influenced children's problem behavior indirectly. In contrast, stressful life events and mother's depression influenced children's problem behavior directly. However, negative family functioning, marital discord and father's depression did not influence mother's child rearing attitudes or children's problem behavior. Mother's child rearing attitudes directly influenced children's social competence and academic achievement and indirectly influenced their problem behavior. Academic achievement did not influence problem behavior directly, but social competence influenced it directly. Mother's child rearing attitude was the most significant factor affecting children's adaptation.

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교육·소득상태 및 건강행위가 건강수준에 미치는 영향 (Relationship of Socioeconomic Status and Health Behaviors with Self-rated Health Status)

  • 윤병준
    • 한국학교ㆍ지역보건교육학회지
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    • 제17권3호
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    • pp.71-85
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    • 2016
  • Objectives: This study was conducted in order to determine how the association between socioeconomic status and health behaviors with self-rated health status among Korean aged 20-64 years. Methods: A nationally representative sample(2,027 men and 2,626 women) from the 2013 Korea National Health and Nutrition Surveys was analyzed. To estimate the odds ratio and 95% confidence intervals, logistic regression was conducted. Results: The study shows that socioeconomic status was related with self-rated health status. that was, lower education and income led to a significant increase in poor health status. The odds ratio of self-rated health status after controlling for age was 2.83(95% CI, 1.60-5.00) for men, 2.32(95% CI, 1.15-3.46) for women among those with the lowest-educated group compared to the highest-educated group. When household income was considered, the odds ratio of self-rated health for men was 3.50(95% CI, 2.11-5.79) and 2.21(95% CI, 1.53-3.20) for women among those in the lowest-income group compared to the highest-income group. Health behaviors had little effect on the relationship between socioeconomic status and self-rated health status. Conclusions: This study found that there existed socioeconomic differences in poor health status in Korean. The effect of education was stronger than that of income for both men and women.

A novel approach to bind graphene oxide to polyamide for making high performance Reverse Osmosis membrane

  • Raval, Hiren D.;Das, Ravi Kiran
    • Membrane and Water Treatment
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    • 제8권6호
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    • pp.613-623
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    • 2017
  • We report the novel thin film composite RO membrane modified by graphene oxide. The thin film composite RO membrane was exposed to 2000 mg/l sodium hypochloride; thereafter it was subjected to different graphene oxide concentration ranging from 50 mg/l to 1000 mg/l in water. The resultant membrane was crosslinked with 5000 mg/l N-hydroxysuccinimide. The performance of different membranes were analysed by solute rejection and water-flux measurement. It was found that 100 mg/l graphene oxide exposure followed by 5000 mg/l N-hydroxysuccinimide treatment resulted in the membrane with the highest solute rejection of 97.78% and water-flux of 4.64 Liter per sqm per hour per bar g. The membranes were characterized by contact angle for hydrophilicity, scanning electron micrographs for surface morphology, energy dispersive X-Ray for chemical composition of the surface, Atomic force microscope for surface roughness, ATR-FTIR for chemical structure identification. It was found that the graphene oxide modified membrane increases the salt rejection performance after exposure to high-fouling water containing albumin. Highly hydrophilic, antifouling surface formation with the nanomaterial led to the improved membrane performance. Moreover, the protocol of incorporating nanomaterial by this post-treatment is simple and can be applied to any RO membrane after it is manufactured.

Correlations among the Continence Function, Cognitive Function and Activities of Daily Living in Elderly Male Patients with Dementia in a Geriatric Hospital

  • Kim, Hong Rae;Shin, Hee Joon;Wang, Joong San
    • 국제물리치료학회지
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    • 제7권1호
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    • pp.972-978
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    • 2016
  • The purpose of this study was to identify correlations among the continence function, cognitive function, and activities of daily living(ADL) in elderly male patients with dementia in geriatric hospitals. The subjects were 64 patients aged 65 or above who were diagnosed with dementia among the hospitalized male patients in a geriatric hospital. For the subjects' cognitive function, a questionnaire developed for the Korean Mini Mental Status Examination(K-MMSE) was used. For the continence function and ADL, data were collected using a patient evaluation table. As a result, a lower level of cognitive function resulted in corresponding higher levels of dependence in all items of ADL except bathing(p<.05), and a lower level of cognitive function led to corresponding declines in the continence function(bowel control, bladder control)(p<.01). In addition, a higher level of dependence in ADL resulted in corresponding higher levels of difficulty in bowel and bladder control(p<.01). This study showed correlations among the cognitive function, ADL, and continence function of elderly men with dementia. The results of this study may be used as basic data for the management and treatment of hospitalized elderly male patients with dementia in geriatric hospitals.

Antibacterial Activity of (2S)-7,4'-dihydroxy-5-methoxy-8-(${\gamma}$, ${\gamma}$-dimethylally)-flavanone against Methicillin-Resistant Staphylococcus aureus

  • Kim, Eun-Sook
    • 동의생리병리학회지
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    • 제23권3호
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    • pp.704-709
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    • 2009
  • The emergence of methicillin-resistant of Staphylococcus aureus (MRSA) and vancomycin-resistant enterococci (VRE) has led to an urgent need for the discovery and development of new antibacterial agents. As part of an ongoing investigation into the antibacterial properties of the natural products, (2S)-7,4'-dihydroxy-5-methoxy-8-(${\gamma}$, ${\gamma}$-dimethylally)-f1avanone (2S-DMDF), isolated from the roots of Sophora flavescens, was found to be antibacterial active MRSA and VRE. Sophora flavescens has been used as antibacterial, antiviral, antiprotozoal, anti-inflammatory. Therefore, this study investigated the antibacterial activity of 2S-DMDF against all the bacterial strains tested. In this result, at the end point of an optically clear well, the minimum inhibitory concentrations (MICs) ranged from 0.97 to 15.6 mg/ml for 2S-DMDF, from 125 to 256 mg/ml for ampicillin, and from 64 to 512 mg/ml for gentamicin with MRSA, also, 7.8 to 15.6 mg/ml for 2S-DMDF, from 125 to 256 mg/ml for ampicillin, and from 512 to 1024< mg/ml for vacomicin with VRE. These findings indicated that the application of the tested 2S-DMDF alone might prove useful in the control and treatment of MRSA and VRE infections.

A Basic Study on the Hat Production for Aged Women

  • Shim, Boo-Ja;Yoo, Hyun
    • 패션비즈니스
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    • 제11권6호
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    • pp.24-34
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    • 2007
  • This study aims to suggest basic data for the production of hats for aged women. The subjects were 151 females who are 60 years old or above and live in Busan. Their hat-wearing reality was inquired and their head parts were measured, which led to the following conclusion: 1. Results of Hat-Wearing Reality Inquiry 64.9% answered they are unsatisfied with the size system of the available hats at present, implying the necessity for improving the current dimension system. 92.7% responded hat dimensions need to be subdivided, while 97.4% were for the necessity of hat size system. 74.8% expressed their will to buy ordered hats because they can find the hats of right sizes and designs. 2. Results of Head-Part Measurement Experiments According to head-part measurement, head circumference A was 53.26cm, head circumference B 54.19cm, and head circumference C 57.69cm on the average. Cluster analysis revealed three types. Type 1 (24%) with small head length and circumference is the smallest head with a wide upper part. Type 2 (33%) has long head height, short bitragion arc A, and thick head breadth. Type 3 (43%), owing to big head circumference and length as well as high values in vertical items. Considering head circumference B (HCB) and bitragion arc A (BAA), a new hat size system of 3 sizes (HCB: BAA) was chosen: S (52cm: 29cm), M (53-55cm: 30cm), and L (56-57cm: 31cm).