• The Korean Journal of Physiology
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• 제16권2호
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• pp.195-207
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• 1982

장기적(長期的)인 채식섭취(菜食攝取)가 혈청(血淸)의 lipoprotein, cholesterol 및 단백량(蛋白量)에 미치는 영향(影響)을 알아보기 위하여 결은 여승(女僧) 45명(名)($20{\sim}35$세)과 대조군(對照群)으로 여대생(女大生) 29명(名)($20{\sim}22$세)을 연구대상(硏究對象)으로 하였다. 하루 열량섭취(熱量攝取)는 여승(女憎)들이 1,945 kcal 였고 여대생(女大生)은 1,815 kcal 였다. 열량구성비율(熱量構成比率)은 여승(女僧)들이 탄수화물(炭水化物) : 단백질(蛋白質) : 지방(地方)=84 : 11 : 5였고 학생(學生)은 70 : 15 : 15였으며 이는 여승(女僧)들의 탄수화물(炭水化物) 편중(偏重) 및 지방섭취부족(脂肪攝取不足)을 보여준다. 신체계측결과(身體計測結果) 여승(女僧)들은 여대생(女大生)보다 신장(身長)을 제외(除朴)하고, 체중(體重), 지방층(脂肪層)두께, 체표면적(體表面積) 및 비만도계수(肥滿度係數)가 모두 높았다. 수축기(收縮期) 및 이완기혈압(弛緩期血壓)은 여승(女憎)과 여대생(女大生)이 거의 같았다. 혈청(血淸)의 총지방(總脂肪), cholesterol 및 단백량(蛋白量)은 여승(女憎)과 여대생간(女大生間)에 유의(有意)한 차이(差異)가 없었다. 그러나 전기영동(電氣泳動)으로 분획(分劃)하여 혈청(血淸)의 high density lipoprotein(HDL), very low density lipoprotein(VLDL) 및 low density lipoprotein(LDL)량(量)을 비교(比較)해 본 결과(結果), 여승(女憎)들의 HDL은 여대생(女大生)보다 낮았으나 LDL은 유의(有意)하게 높았다. Cholesterol분획결과(分劃結果)도 역시 여승(女憎)들의 HDL-cholesterol값은 여대생(女大生)보다 유의(有意) 하게 낮은 반면(反面) LDL-cholesterol은 유의(有意)하게 높았다. Lipoprotein과 cholesterol간(間)의 상관계수(相關係數)(r)를 계산(計算)한 결과(結果) LDL과 LDL-cholesterol(r=0.40), VLDL과 VLDL-cholesterol(r=0.85), HDL과 HDL-cholesterol(r=0.45), 혈청총지방량(血淸總脂防量)과 cholesterol(r=0.66) 및 혈청(血淸) 총(總) cholesterol과 LDL-cholesterol(r=0.79) 간(間)에는 유의(有意)한 상관관계(相關關係)를 보여주었다. 그러나 혈청(血淸) cholesterol과 음식섭취(飮食攝取) 및 신체계측결과간(身體計測結果間)에는 유의(有意)한 상관관계(相關關係)가 나타나지 않았다. 혈청단백량(血淸蛋白量)은 여승(女憎)과 여대생간(女大生間)에 차이(差異)가 없었다. 이상(以上)의 결과(結果)는 여승(女憎)들의 장기적(長期的)인 채식섭취(菜食攝取)로 인(因)해 인체(人體)의 lipoprotein 및 cholesterol 대사(代謝)에 영향(影響)이 있음을 시사(示唆)해 주고 있다.

• 대한간호학회지
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• 제28권1호
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• pp.184-192
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• 1998

This study was done to examine the correlations between weight, BMI and risk factors of coronary heart disease in men and women in their forties and fifties. The subjects were 412 adults. who had regular health examinations between January and December of 1996 at S-Hospital in Seoul. The data were analyzed using ANOVA, Scheffe test, and Pearson correlation coefficient. The results are as follows : 1. The men between 50 and 59 years of age had higher levels for BMI, weight, systolic blood pressure, diastolic blood pressure, total cholesterol. LDL-cholesterol, triglyceride, fasting blood sugar, plasminogen activator-1, and hemoglobin A,C than the group of women in their forties. Yet. HDL-cholesterol was lower than in the former group. 2. In the group of men in their forties, weight was significantly correlated to diastolic blood pressure(r=.22), LDL-cholesterol(r=.20), plasminogen activator-inhibitor-1(r=.35) HDL-cholesterol(r=-.19). Their BMI was significantly correlted to systolic blood pressure(r=.27), diastolic blood pressure (r=.33), total cholesterol(r=.23), LDL-cholesterol (r=.26), plasminogen activator-1(r=.36) and HDL-cholesterol(r=-.25). 3. As for the group of women in their forties weight was significantly correlated to systolic blood pressure(r=.20), diastolic blood pressure(r=.22), triglyceride(r=.32) , plasminogen activator inhibitor-1 (r=.30) and HDL-cholesterol(r= -.37). Their BMI was significantly correlated to diastolic blood pressure (r=.25) triglyceride(r=.47), plasminogen activator-1 (r=.35), fibrinogen(r=.27) and HDL-cholesterol(r=-.47). 4. In the group of men in their fifties. weight was significantly correlated to total cholesterol (r=32), LDL-cholesterol(r=.29). plasminogen activator inhibitor-1(r=.26). Their BMI was significantly correlated to systolic blood pressure(r=.24), diastolic blood pressure (r=.22), total cholesterol (r=.34), LDL-cholesterol (r=.32), and plasminogen activator-1(r=.25). 5. In the group of women in their fifties, weight was significantly correlated to diastolic blood pressure(r=.33), total cholesterol(r=.21), LDL-cholesterol(r=.20), plasminogen activator inhibitor-1 (r=.43) and HDL-cholesterol(r=-.21). Their BMI was significantly correlated to systolic blood pressure(r=.25), diastolic blood pressure(r=.40), total cholesterol(r=.24), LDL-cholesterol(r=.24), triglyceride(r=22), and HDL-cholesterol (r=-.30). The above findings indicate that the BMI was more predictive than weight as a risk factor for coronary artery disease for men and women in their forties and fifties.

• 한국지역사회생활과학회지
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• 제19권1호
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• pp.113-123
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• 2008

This study was performed to find and compare the characteristics of dietary factors and obesity indices on serum lipid profiles using 407 healthy adult males that had physical examinations conducted at the general hospital located in Suwon. The subjects were divided 56.3% for the normal group, 16.7% for TG, 14.5% for TC and 12.5% for TC TG group, respectively. When comparing the blood lipid profiles to normal group, TC group was high in both total cholesterol and LDL-cholesterol, TG group was high in triglyceride and low in HDL-cholesterol, TC TG group was high in triglyceride, total cholesterol, LDL-cholesterol and low in HDL-cholesterol. In comparison of blood lipid profiles with normal group, among anthropometric factors, body weigh, BMI (Body Mass Index) and WHR (Waist Hip Ratio) showed significant differences. TC group was high in both total cholesterol and LDL-cholesterol, and TG group was high in triglyceride and low in HDL-cholesterol. TC TG group was high in triglyceride, total cholesterol and LDL-cholesterol, and was low in HDL-cholesterol. Body weigh of TG group was significantly higher than that of normal group (p<0.05). BMI and WHR of TG group and TC TG group were significantly higher than those of normal group (p<0.05). Total cholesterol was mainly related to the intake of animal lipids and alcoholic beverage. Serum triglyceride levels were closely related with lipid intake and high BMI in this group. In TC TG group, BMI and WHR were high. As well, serum LDL-cholesterol was high and HDL-cholesterol was low which indicates TC TG group had the most undesirable blood lipid profiles. Therefore, it may be necessary to manage BMI and WHR to prevent hyperlipidemia and obesity for adult males in Suwon.

• 대한의생명과학회지
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• 제16권1호
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• pp.19-24
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• 2010

We analyzed and compared the concentration of total cholesterol (CHOL), high density lipoprotein (HDL) cholesterol, low density lipoprotein (LDL) cholesterol and triglyceride (TG) in serum and the serum protein electrophoresis fractions of thyroid disease patients. In comparison with the average of reference, our data showed that the average concentration of CHOL, LDL cholesterol and TG in hyperthyroidism patients were decreased significantly, but HDL cholesterol was increased significantly. In hypothyroidism patients, CHOL, HDL cholesterol, LDL cholesterol and TG were all increased significantly. In comparison of the concentration of lipids in each patient to reference range, 28.3% of hyperthyroidism patients showed abnormally low level of total cholesterol. In the patients with hypothyroidism, the percentage of patients showed abnormally high level of CHOL, HDL cholesterol, LDL cholesterol and TG were 37.7%, 10%, 68.8% and 49.1%, respectively. In our studies of serum protein electrophoresis, the average of ${\alpha}_2$-globulin and $\gamma$-globulin in hyperthyroidism patients were increased and $\beta$-globulin was decreased significantly. In hypothyroidism patients, the average of $\gamma$-globulin was increased and $\beta$-globulin was decreased significantly. In comparison of protein fractions of each patient to reference range, 38.3% and 50.0% of hyperthyroidism patients showed abnormally high levels of ${\alpha}_2$-globulin and $\gamma$-globulin, but 73.3% of patients showed abnormally low level of $\beta$-globulin. In hypothyroidism patients, 70.4% of patients were abnormally decreased in $\beta$-globulin and 63.9% of patients were abnormally increased in $\gamma$-globulin. These data suggest that the concentrations of CHOL, HDL cholesterol, LDL cholesterol and TG are not critical data for clinical interpretation of hyperthyroidism, but the levels of them are useful for interpretation of hypothyroidism patients. Our results of serum protein electrophoresis suggest that the concentration of serum protein electrophoresis fractions can be useful to understand the thyroid disease.

• Journal of Korean Biological Nursing Science
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• 제19권2호
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• pp.107-112
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• 2017

Purpose: The purpose of this study was to identify the lipid profile ratios as factors affecting disease progress in patients with high-grade primary brain cancers undergoing concurrent chemoradiotherapy (CCRT) and adjuvant chemotherapy. Methods: The levels of lipid profile ratios were evaluated by looking at the total cholesterol (TC) to high-density lipoprotein (HDL)-cholesterol (TC/HDL-c), low-density lipoprotein (LDL)-cholesterol to HDL-cholesterol (LDL-c/HDL-c), and triglycerides to HDL-cholesterol (TG/HDL-c). This descriptive research was conducted 7 months after the initiation of CCRT and adjuvant chemotherapy. Results: A total of 36 patients with newly diagnosed primary malignant brain cancer were included in the study. The levels of lipid profile ratios such as TC/HDL-c, LDL-c/HDL-c, TG/HDL-c were significantly different between the patients with and without disease progress at 7 months after initiation of CCRT and adjuvant chemotherapy. Conclusion: The lipid profile ratios were indicators affecting disease prognosis with tumor-related factors at 7 months after initiation of CCRT and adjuvant chemotherapy. Therefore, lipid profile ratios indicating hyperlipidemia in patients with high-grade brain cancers should be carefully monitored during and after cancer-related therapy.

• Journal of Acupuncture Research
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• 제40권4호
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• pp.351-355
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• 2023

Background: Wet cupping (WC) is an efficient and cost-effective technique for removing metabolic waste from the bloodstream via the skin. The study aimed to examine the effect of WC on cholesterol levels including total cholesterol (TC), high-density lipoprotein cholesterol (HDL-C), and low-density lipoprotein cholesterol (LDL-C) in a Sudanese population. Methods: In this prospective cross-sectional study, 30 participants undergoing regular WC therapy were enrolled. Blood samples collected twice: pre-WC therapy (case group) and 10-14 days afterward (controls). Results: Of the participants, 56.67% were male and 43.33% were female, aged 24-69. Pre-WC TC and LDL-C levels were significantly higher than the post-WC control group (p = 0.001). Conversely, HDL-C levels decreased significantly in the pre-WC cases compared to controls (p = 0.001). No significant sex-based difference in mean cholesterol levels (p > 0.05). Conclusions: After WC, males and females experienced significant reductions in TC and LDL-C, and significant increase in HDL-C.

• 한국식품영양학회지
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• 제14권2호
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• pp.113-119
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• 2001

1. 수축기 혈압은 운동을 하고 있는 군에서 약간 낮았으나 이완기 혈압은 유의성 있는 차이를 보이지 않았다. 운동을 하고 있는 여대생의 경우 체지방량이 낮게 나타난 반면 제지방량은 변화가 없어 운동 여부에 의한 차이가 거의 보이지 않았다. 또 혈중 포도당 함량은 규칙적인 운동을 하고 있는 여대생에서 다소 높은 수준이었다. 2. 체지방율은 지속적인 운동을 하고 있는 여대생에 서 유의성은 없었지만 약간 낮았으며 혈청 총 콜레스테롤과 중성지방의 농도 역시 유의성 있게 낮게 나타났다. HDL 콜레스테롤 농도는 두 군 모두 거의 비슷한 수준으로 군간에 뚜렷한 차이를 보이지 않았던 반면 LDL 콜레스테롤의 경우 운동에 의해서 유의성 있게 낮게 나타났다. 따라서 규칙적인 운동에 의해서 HDL-Chol/Total-Chol 비율은 증가되었으며 LDL-Chol/HDL-Chol의 비율은 낮았다. 3. 혈액중 지단백질의 상대적인 분포는 HDL(%)의 경우 지속적인 운동을 하고 있는 여대생의 경우 일반 여대생에 비해 거의 차이가 없었고 LDL(%)는 유의성 있게 낮았던 반면 VLDL( %)는 오히려 높게 나타났다. Plasma의 지방산 조성중 포화 지방산 함량은 운동을 하고 있는 여대생에서 약간 높았지만 다가 불포화 지방산 함량은 같은 수준으로 두 군간에 차이를 보이지 않았다.

• Journal of Ginseng Research
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• 제10권1호
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• pp.114-121
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• 1986

고려 인삼 뿌리에서 얻은 사포닌 분획이 고cholesterol 식이로 2주내지 4주간 사육한 토끼의 혈청 지단백질 분포에 미치는 영향을 조사하였다. 고cholesterol 식이를 인삼과 함께(시험군) 또는 단독(대조군)으로 2~4주간 투여한 토끼의 혈청 극저밀도 지단백질(VLDL)과 저밀도 지단백질(LDL)이 다같이 크게 증가하는 반면 고밀도 지단백질(HDL)의 농도는 저하 하였다. 그러나 VLDL과 LDL 농도의 증가율이나 HDL 농도의 저하율은 인삼을 투여한 토끼군에서 현저히 적었으며 인삼사포닌의 고cholesterol 혈증 개선작용이 VLDL의 LDL 농도를 낮추고 HDL의 농도를 높이기 때문인 것으로 생각된다.

• 한국가금학회지
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• 제40권4호
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• pp.337-349
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• 2013

본 총설은 논란이 되고 있는 계란 콜레스테롤이 심장질환과 관련성이 없다는 것을 증명하기 위하여 지난 50여 년간의 연구 결과를 조사하였다. 그 결과, 식이로 섭취된 콜레스테롤은 혈액 콜레스테롤 농도에 큰 영향을 미치지 않는 것이 밝혀졌다. 더욱이 고콜레스테롤혈증이 있는 중년 남녀에게 1일 2개의 계란을 더 섭취한 실험에서도 혈액 콜레스테롤이 증가되지 않는 것으로 나타났다. 식이 콜레스테롤 섭취가 증가하면 LDL-콜레스테롤 뿐 아니라, HDL-콜레스테롤도 같이 증가하여 심장질환 위험의 중요 지표인 LDL : HDL 비율은 거의 변화가 없었다. 특히 노인에게서 더 좋은 지표로 밝혀진 HDL-콜레스테롤이 증가하므로, 콜레스테롤 섭취는 심장질환 예방에 좋은 것으로 나타났다. 따라서 계란의 섭취는 건강에 나쁘다고 알려진 인식은 사실이 아니며, 오히려 심장질환 예방에 효과적인 것으로 밝혀졌다. 또한, 계란 섭취량에 관한 공식적인 기준도 없는 것으로 나타났다. 따라서 이와 같은 증거들은 더 이상 계란에 대한 오해와 불신이 없기를 제안한다.

• 한국식품위생안전성학회지
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• 제12권1호
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• pp.83-95
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• 1997

This study showed the effect of fermented milk on the cholesterol level of Korean. 130 persons among the teachers of elementary, middle and high schools, professors and graduate school students were divided into two groups according to their cholesterol level and provided with fermented milk 300 $m\ell$ dairly from Sep.25 to No. V3. They were given blood test at 20 days and 40 days after drinking fermented milk, and surveyed about their ordinary life style and the change of fecal condition. Cholesterol, LDL and the ratio of LDL and HDL in blood were significantly decreased in both high cholesterol group and normal group while HDL cholesterol was notably increased. TG showed slightly tendency of decrease in normal group while no changed in high group. There is no significant change in cholesterol level after drinking fermented milk among groups which are divided by factors of dringking, smoking, caffeine, B.M.I. and family history. The research also showed that drinking fermented milk improved the fecal frequency and fecal condition.