• The Korean Journal of Pesticide Science
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• v.4 no.4
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• pp.77-80
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• 2000

This study was carried out to investigate infection process, symptoms and $LD_{50}$ values of the entomopathogenic fungus cordyceps, Paecillomyces japonica, on the domestic silkworm, Bombyx mori. Susceptibility of infection in the silkworms by cordyceps, Paecillomyces japonica, was 100% in $10^{7}$ block, 96% in $10^{6}$ block, 76% in $10^{5}$ block, 44% in $10^{4}$ block, 28% in $10^{3}$ block and 8% in $10^{2}$ block. Cordyceps, Paecillomyces japonica, was highly infectious to the silkworms. A pathogenicities of cordyceps, Paecillomyces japonica, may be highly virulent because of the low resistance or high susceptibility of the silkworms. Dosage of the pathogen of $LD_{50}$ was $3.78{\times}10^{3}\;spores/mm^{3}$.

• Proceedings of the KIEE Conference
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• 2006.10c
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• pp.273-275
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• 2006

Ladder Diagram(LD) is the most widely utilized among many sorts of existing programs using for the design of process control system. But it is very difficult to grasp sequential flow of control logic. In this paper, we proposed the method that we can control a lot of blocks. We used PLC in process control system. And, in order to design we used Sequential Function Chart(SFC). In this paper, we proposed the method of block contro. and confirmed feasibility through a simulation.

• Molecular & Cellular Toxicology
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• v.2 no.1
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• pp.7-10
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• 2006

We performed comprehensive SNP validation and linkage disequilibrium (LD) analysis of the c-fos induced growth factor (Figf) gene in Korean population. Out of 32 SNPs, only 9 SNPs were polymorphic in Korean population. Validated SNPs formed a single extended haplotype block with strong LD through the entire length of the gene. Tagging SNP analysis picked only 2 SNPs to represent most of the genetic variation information of the Figf gene. Our results demonstrate the utility of LD block and tagging SNP analysis for an efficient way of performing a candidate gene based association study.

• Proceedings of the Korean Information Science Society Conference
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• 2004.04b
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• pp.331-333
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• 2004

본 연구는 Haplotype 데이터에서 나타나는 별개의 Haplotype의 수를 최소화하는 블록으로 분할하는 방법을 제안한다. Multi-population case인 Haplotype 데이터를 분석하기 위해 패턴의 개수를 최소한으로 줄이는 볼록 분할 방법은 전산학적인 최적해의 의미를 가지게 되며, 이와 더불어 생물학적인 의미를 가지는 블록 경계를 찾기 위해 ｜D'｜ 을 계산하고 LD를 분석하였다 분석된 LD는 블록 분할 알고리즘에서 블록 결정 함수로 사용하였으며, 이에 대한 검정은 X$^2$-test를 통해 이루어졌다. 많은 Sample로 구성된 Haplotype 데이터로부터 평균 패턴의 개수를 최소화하고 긴 블록 길이를 가지는 블록 분할의 결과를 얻었다.

• Korean Journal of Optics and Photonics
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• v.19 no.2
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• pp.140-143
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• 2008

The integrated external cavity laser has been fabricated with a 1550 nm FP-LD, an optical filter, a micro ball lens and accurate ceramic blocks using a micro-block stacking (MBS) technique. The integrated external cavity laser module whose size is only $2.0{\times}2.1{\times}0.7\;mm^3$ has been mounted on the TO-CAN package. For the case of the 1.8% transmission filter, the single mode characteristic has been obtained with the optical power of -27.1 dBm and the SMSR of 31.7 dB.

• The KIPS Transactions:PartA
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• v.13A no.1 s.98
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• pp.79-86
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• 2006

Recently the tagSNP selection problem has been researched for reducing the cost of association studies between human's diversities and SNPs. General approach for this problem is that all of SNPs are separated into appropriate blocks and then tagSNPs are chosen in each block. Marsel in this paper is the system that involved the concept of linkage disequilibrium for overcoming the problem that the existing block partitioning approaches have short of biological meanings. In most approaches, the contiguous regions, which recombinations have LD coefficient |D'| and then tagSNP selection step is performed. And MarSel guarantees the minimum tagSNP selection using entropy-based optimal selection algorithm when tagSNPs are chosen in each block, and enables chromosome-level association studies using efficient memory management technique when input is very large-scale dataset that is impossible to be processed in the existing systems.

• Proceedings of the Korean Information Science Society Conference
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• 2004.10b
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• pp.253-255
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• 2004

인간(human)에게 나타나는 다양성(variation)은 인체의 유전체(genome) 안에서 발생된 SNP(Single Nucleotide Polymorphism)에 의해 나타난다고 알려져 있다. 유전체내의 SNP과 다양성에 대한 연관 연구(Associate study)를 할 때에 약 30여 억 개로 추정되는 염기서열(DNA sequence)물 모두 분석한다면 많은 비용과 시간을 필요로 할 것이다. 이런 비용과 시간을 줄이기 위친 적은 수의 대표 SNP(=tagSNP)을 찾는 연구가 현재 진행 중이다. 우리는 LD계수｜D;｜을 block 분할에 이용하여 생물학적인 의미를 부여한 후, 전산적인 최적해를 찾는 접근을 이용했다. 또한, 기존 연구에서는 large-scale data에 대한 처리가 불가능해서 chromosome의 일부분의 데이터에 대해서안 분석이 시도되었다. 더욱 광범위한 분석을 위해서 chromosome 단위의 처리가 필요하다. 우리는 chromosome단위의 SNP data를 한 번에 처리가 가능한 시스템인 MarSel를 구현하였다

• Archives of Reconstructive Microsurgery
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• v.6 no.1
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• pp.56-62
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• 1997

Latissimus dorsi(LD) muscle is the largest transplantable block of vascularized tissue. Since LD free flap was introduced in 1970's, this flap has been widely used for the reconstruction of large soft tissue defect of the limb. From 1981 to 1996, we had experienced 37 cases of LD free flap. Serratus anterior muscle was combined with LD in three of them whose defects were very large. The average age of the patients was 31 years(range : 4-74 years), and thirty one patients were male. Trauma was cause of the defect in every case. For the recipient sites, the foot and ankle was the most common(22 cases); and the knee and lower leg(11 cases), the elbow and forearm(2 cases), the hand(2 cases) were the next. The duration of follow-up was averaged as 16 months(range: 6 months-12 years). Thirty one cases(84%) out of 37 were successful transplantations. In one case the failure of the flap was due to heart attack and subsequent death of the patient. One failure was caused by sudden violent seizure of the patient who had organic brain damage. Immediate reexploration of the flap was performed in 4 patients, and the flap survived in three of them. There was one necrosis of the grafted split-thickness skin on the survived LD flap. LD free flap was considered as one of the good methods, for the reconstruction of the large soft tissue defect of the limb.

• ETRI Journal
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• v.33 no.5
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• pp.695-703
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• 2011

The number of adders and critical paths in a multiplier block of a multiple constant multiplication based implementation of a finite impulse response (FIR) filter can be minimized through common subexpression elimination (CSE) techniques. A two-bit common subexpression (CS) can be located recursively in a noncanonic sign digit (CSD) representation of the filter coefficients. An efficient algorithm is presented in this paper to improve the elimination of a CS from the multiplier block of an FIR filter so that it can be realized with fewer adders and low logical depth as compared to the existing CSE methods in the literature. Vinod and others claimed the highest reduction in the number of logical operators (LOs) without increasing the logic depth (LD) requirement. Using the design examples given by Vinod and others, we compare the average reduction in LOs and LDs achieved by our algorithm. Our algorithm shows average LO improvements of 30.8%, 5.5%, and 22.5% with a comparative LD requirement over that of Vinod and others for three design examples. Improvement increases as the filter order increases, and for the highest filter order and lowest coefficient width, the LO improvements are 70.3%, 75.3%, and 72.2% for the three design examples.

• The KIPS Transactions:PartD
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• v.11D no.2
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• pp.415-422
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• 2004

Automation systems improve the productivity of works which relate to product design, facilities management, fault processing and quality evaluation. In these systems, the description language for monitoring and control process is called new control language. These are five flow control languages : IL, ST, FBD, SFC and LD. IL and ST are based on left form. FBD, SFC and LD are based on graphic form. Generally, a software which monitors and controls a system is allowed to use just one flow control language. It is impossible to use more than two languages for simulation in the same system environment. In this paper, we analyzed the characteristics of flow control languages and the process of programming in the legacy system. In addition, for the Integrated processing of languages, we propose Extended ST based on the high-level ST language. Based on this research, we implement a graphical language editor and EST-IL convertor. The graphical language editor makes sequence rules, and converts graphical language into EST. EST-IL convertor has a function to convert EST into IL which is similar to assembly language. As the result of this paper, we present a scheme which integrates all the flow control language processing based on IL.