• Korean Chemical Engineering Research
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• v.44 no.6
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• pp.555-562
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• 2006

Recently, liquid chromatography (LC) has been used more frequently to separate drugs and natural substances. Especially, to selection of the solutes from the products, the operation condition of analytical chromatography should be necessarily determined. So accurate computer modeling and simulation of chromatographic performances has become a necessary part of the development and design of processes. High-Purity Separation Lab. Inha University developed the resulting HCI software for the purpose of the optimization of chromatographic performances. The HCI program was utilized to find the optimum operating condition more accurately and rapidly, reducing the number of many possible experiments. The elution profiles were calculated by the plate theory based on the three retention mechanism of capacity factor.

• Journal of Power Electronics
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• v.16 no.1
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• pp.351-361
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• 2016

Power quality is a critical issue in distribution systems, where a dynamic voltage restorer (DVR) is commonly used to mitigate the voltage disturbances for loads. This paper deals with a nonlinear control for the three-phase four-wire (3P-4W) DVR under a grid voltage unbalance and nonlinear loads in the distribution system, where a novel control scheme based on the feedback linearization technique is proposed. Through feedback linearization, a nonlinear model of a DVR with a PWM voltage-source inverter (VSI) and LC filters is linearized. Then, the controller design of the linearized model is performed by applying the linear control theory, where the load voltages are kept constant by controlling the d-q-0 axis components of the DVR output voltages. To keep the load voltage unchanged, an in-phase compensation strategy is employed, where the load voltages are recovered to be the same as the previous voltage without a change in the magnitude. With this strategy, the performance of the DVR becomes faster and more stable even under unbalanced source voltages and nonlinear loads. The validity of the proposed control strategy has been verified by simulation and experimental results.

• Journal of Power Electronics
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• v.13 no.6
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• pp.1058-1069
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• 2013

This paper proposes and designs a new output filter called an LCFL filter for application to three phase three wire shunt active power filters (SAPF). This LCFL filter is derived from a traditional LCL filter by replacing its capacitor with a C-type filter, and then constructing an L-C-type Filter-L (LCFL) topology. The LCFL filter can provide better switching ripple attenuation capability than traditional passive damped LCL filters. The LC branch series resonant frequency of the LCFL filter is set at the switching frequency, which can bypass most of the switching harmonic current generated by a SAPF converter. As a result, the power losses in the damping resistor of the LCFL filter can be reduced when compared to traditional passive damped LCL filters. The principle and parameter design of the LCFL filter are presented in this paper, as well as a comparison to traditional passive damped LCL filters. Simulation and experimental results are presented to validate the theoretical analyses and effectiveness of the LCFL filter.

• Journal of the Korea Institute of Information and Communication Engineering
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• v.11 no.12
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• pp.2205-2209
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• 2007

In this paper, a voltage controlled oscillator(VCO) of core components for wireless subscriber network is designed. The type of oscillator is colpits method and the oscillator device uses a LC resonator. The product is made on FR-4 substrate with dielectric constant of 4.6. The designed VCO is operated at 3.2V, 10mA and has output value of 0.67dB. The VCO's phase noise property is -102DBc/Hz at offset frequence of 100kHz. The fabricated VCO is the same as target value and can be used for wireless subscriber network.

• Journal of Microbiology and Biotechnology
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• v.33 no.1
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• pp.114-122
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• 2023

A family of signal transduction pathways known as wingless type (Wnt) signaling pathways is essential to developmental processes like cell division and proliferation. Mutation in Wnt signaling results in a variety of diseases, including cancers of the breast, colon, and skin, metabolic disease, and neurodegenerative disease; thus, the Wnt signaling pathways have been attractive targets for disease treatment. However, the complicatedness and large involveness of the pathway often hampers pinpointing the specific targets of the metabolic process. In our current study, we investigated the differential metabolic regulation by the overexpression of the Wnt signaling pathway in a timely-resolved manner by applying high-throughput and un-targeted metabolite profiling. We have detected and annotated 321 metabolite peaks from a total of 36 human embryonic kidney (HEK) 293 cells using GC-TOF MS and LC-Orbitrap MS. The un-targeted metabolomic analysis identified the radical reprogramming of a range of central carbon/nitrogen metabolism pathways, including glycolysis, TCA cycle, and glutaminolysis, and fatty acid pathways. The investigation, combined with targeted mRNA profiles, elucidated an explicit understanding of activated fatty acid metabolism (β-oxidation and biosynthesis). The findings proposed detailed mechanistic biochemical dynamics in response to Wnt-driven metabolic changes, which may help design precise therapeutic targets for Wnt-related diseases.

• Journal of Microbiology and Biotechnology
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• v.28 no.1
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• pp.1-11
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• 2018

An antioxidant peptide derived from Pinctada fucata meat using an Alcalase2.4L enzymatic hydrolysis method (named AOP) and identified by LC-TOF-MS has promising clinical potential for generating cosmetic products that protect skin from sunshine. To date, there have been few published studies investigating the structure-activity relationship in these peptides. To prepare antioxidant peptides better and improve their stability, the design and expression of an antioxidant peptide from Pinctada fucata (named DSAOP) was studied. The peptide contains a common precursor of an expression vector containing an ${\alpha}$-helix tandemly linked according to the BamHI restriction sites. The DNA fragments encoding DSAOP were synthesized and subcloned into the expression vector pET-30a (+), and the peptide was expressed mostly as soluble protein in recombinant Escherichia coli. Meanwhile, the DPPH radical scavenging activity, superoxide radical scavenging activity, and hydroxyl radical scavenging activity of DSAOP $IC_{50}$ values were $0.136{\pm}0.006$, $0.625{\pm}0.025$, and $0.306{\pm}0.015mg/ml$, respectively, with 2-fold higher DPPH radical scavenging activity compared with chemosynthesized AOP (p < 0.05), as well as higher superoxide radical scavenging activity compared with natural AOP (p < 0.05). This preparation method was at the international advanced level. Furthermore, pilot-scale production results showed that DSAOP was expressed successfully in fermenter cultures, which indicated that the design strategy and expression methods would be useful for obtaining substantial amounts of stable peptides at low costs. These results showed that DSAOP produced with recombinant Escherichia coli could be useful in cosmetic skin care products, health foods, and pharmaceuticals.

• The Transactions of The Korean Institute of Electrical Engineers
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• v.57 no.10
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• pp.1782-1789
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• 2008

This paper presents the design of acoustic resonance(AR) free and dimmable electronic ballast for 1kW Metal-Halide Lamp(MHL). The proposed Ballast consists of a Full-Bridge(FB) rectifier, a passive power factor correction(PFC) circuit, a full-bridge inverter, an ignitor using LC resonance and a control circuit for frequency modulation and dimming control. Whereas a passive PFC provides advantages in terms of high reliability and low cost for constructing the circuit, it is difficult to supply a stable voltage because of the output voltage ripple that occurs with a period of 120Hz. Although the ballast can be designed with a small size and a light weight if it is driven at a switching frequency between 1 and 100 kHz, AR will occur if the eigenvalue frequency of the lamp coincides with the inverter's operation frequency. The operation frequency was modulated in real time according to the output voltage ripple to compensate for the variation in power supplied to the lamp and eliminate AR. For dimming, the method, which modulated drive frequency of FB inverter using the control of DC level by microprocessor, was used. The Dimming ranged at least from 600W to 1kw as rated power of the lamp with 4 stages. Performance of the proposed technique was validated through numerical analysis, computer simulation using Pspice and by applying it to an electronic ballast for a prototype 1kW MHL.

• Journal of the Korean Society of Clothing and Textiles
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• v.30 no.6 s.154
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• pp.870-879
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• 2006

In this study, the difference in the mechanical properties of silver and cotton weft knitted fabrics was studied. Six silver fabrics for the summer ladies' knit outwear were knitted varying knit structure and fabric density. Two commercial cotton knitted fabrics were selected to compare the properties. subjective sensation of hand of the fabrics was also studied. Mechanical properties of the fabric samples were measured by KES-FB system. From these, primary hand values(HV) were evaluated by the conversion equation (KW-403-KTU) and the total hand value(THV) was carried out according to the KW-304 Summer. The result of the research show that silver weft knitted fabrics had lower LT, RT, G, 2HG and higher EM, W, LC, WC, RC than cotton weft knitted fabrics. The use of silver yam contributed to increase in surface roughness of knitted fabrics. As the silver knitted fabrics became thicker compressional energy increased. The use of silver yarns contributed to much better fabric handle compared with the use of cotton yam only. It appeared that coefficient of friction of tuck stitch was larger than that of plain and interlock stitch. KOSHI and FUKURAMI values of the tuck samples were significantly higher than those values of the plain and interlock samples, while SHARI values were low in general. The total hand value of tuck stitch was higher than those of interlock and plain stitch.

• Journal of Satellite, Information and Communications
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• v.11 no.4
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• pp.44-47
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• 2016

In these days, interest of systems and services using TVWS(TV White Space) are increased, communication systems and services for TVWS have been actively studied. The unoccupied frequency in TVWS is different according to the geographical location and the time of day. RF systems having a frequency tunable bandpass filter operated in TVWS could be efficiently used. In this paper, a frequency tunable bandpass filter operated in 470 ~ 698MHz is designed and implemented. In consideration of simple control and physical size, the tunable bandpass filter is designed with 2-pole. The implemented tunable bandpass filter has the operating frequency band of 470 ~ 698MHz with control voltages of 1.58 ~ 3.93V, the insertion loss of maximum 4.78dB and the return loss of below 10dB. The implemented frequency tunable bandpass filter can be directly used in the RF receiver for TVWS and the design procedures could be used for developing a high power tunable bandpass filter as the basic research data.

• Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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• 2018.05a
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• pp.59-60
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• 2018

In this paper, we studied a design method for a band-pass waveguide filter with a modified H-type resonant iris (RI) placed in a thin transverse wall of a rectangular waveguide. The horizontal straight gap at the center of a conventional H-shaped iris is modified to a U-shaped one to increase the equivalent capacitance, and the equivalent inductance is improved by changing the vertical two straight slots into C-shaped ones. A third-order band pass filter using the proposed modified H-shaped iris was designed and, it was observed that the filter operated in the frequency range of 9.22-9.75 GHz with its insertion loss of 0.5 dB and return loss of 17 dB.