• Transactions of the Korean Society of Mechanical Engineers B
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• v.37 no.7
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• pp.683-693
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• 2013

In this study, the mixing characteristics in lid-driven cavity flows were studied numerically by using a hybrid lattice Boltzmann method (HLBM). First, we compared the numerical results from single-relaxation-time (LB-SRT) and multi-relaxation-time (LB-MRT) models to examine their reliability. In most of the cavity flow, the results from both the LB-SRT and the LB-MRT models were in good agreement with those using a Navier-Stokes solver for Re=100-5000. However, the LB-MRT model was superior to the LB-SRT model for the simulation of higher Reynolds number flows having a geometrical singularity with much lesser spatial oscillations. For this reason, the LB-MRT model was selected to study the mass transport in lid-driven cavity flows, and it was demonstrated that mass transport in the fluid was activated by a recirculation zone in the cavity, which is connected from the top to the bottom surfaces through two boundary layers. Various mixing characteristics such as the concentration profiles, mean Sherwood (Sh) numbers, and velocity were computed. Finally, the detailed transport mechanism and solutions for the concentration profile in the cavity were presented.

• Journal of Electrical Engineering and information Science
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• v.3 no.2
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• pp.274-279
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• 1998

We investigate a Leaky Bucket(LB) scheme with a threshold in the data buffer, where leaky rate changes depending on the contents of data buffer. We use the fluid flow model for the analysis of the LB scheme with a threshold. We model the bursty input source as markov modulated fluid flow(MMFF) As performance measures we obtain loss probability and mean delay. We present some numerical results to show the effects of the level of a threshold, the rate of token generation, the size of token pool, and the size the data buffer on the performances of the LB scheme with a threshold.

• Journal of the Korean Data and Information Science Society
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• v.27 no.2
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• pp.559-564
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• 2016

The Durbin-Watson (DW) test in regression model and the Ljung-Box (LB) test in ARMA (autoregressive moving average) model are typical examples of correlated error tests. The DW test is used for detecting autocorrelation of errors using the residuals from a regression analysis. The LB test is used for specifying the correct ARMA model using the first some sample autocorrelations based on the residuals of a tted ARMA model. In this article, simulations with four data generating processes have been carried out to evaluate their performances as correlated error tests. Our simulations show that the DW test is severely dependent on the assumed AR(1) model but isn't sensitive enough to reject the misspecified model and that the LB test reports lackluster performance in general.

• The Korean Journal of Applied Statistics
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• v.29 no.1
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• pp.61-73
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• 2016

We consider the wild bootstrap Ljung-Box (LB) test for autocorrelation in residuals of fitted multivariate time series models. The asymptotic chi-square distribution under the IID assumption is traditionally used for the LB test; however, size distortion tends to occur in the usage of the LB test, due to the conditional heteroskedasticity of financial time series. In order to overcome such defects, we propose the wild bootstrap LB test for autocorrelation in residuals of fitted vector autoregressive and error correction models. The simulation study and real data analysis are conducted for finite sample performance.

• Journal of Microbiology and Biotechnology
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• v.33 no.6
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• pp.823-830
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• 2023

Lactococcus lactis is a lactic acid bacterium and used in the dairy food industry. The ameliorating effects of Lactobacillus species on atopic dermatitis (AD) have been extensively studied, but the specific effect of L. lactis strains has not yet been investigated. In this study, the efficacy of L. lactis LB 1022, isolated from natural cheese, was evaluated using RAW 264.7, HMC-1 and HaCaT cell lines and an ovalbumin-sensitized AD mouse model. L. lactis LB 1022 exhibited nitric oxide suppression and anti-allergy and anti-inflammatory activity in vitro. Oral administration of L. lactis LB 1022 to AD mice significantly reduced the levels of IgE, mast cells, and eosinophils, and a range of T cell-mediated T helper Th1, Th2, and Th17-type cytokines under interleukin (IL)-10, transforming growth factor-β (TGF-β), thymus and activation-regulated chemokine (TARC), and thymic stromal lymphopoietin (TSLP). In addition, L. lactis LB 1022 treatment increased the concentration of short-chain fatty acids. Overall, L. lactis LB 1022 significantly modulated AD-like symptoms by altering metabolites and the immune response, illustrating its potential as candidate for use in functional food supplements to alleviate AD.

• Korean Journal of Veterinary Pathology
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• v.1 no.1
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• pp.40-45
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• 1997

The phototoxic potentials of LB20304a a new quinolone compound being developed by LG Chemical Ltd, and reference compounds (Ciprofloxacin; CPFX, Enoxacin; ENX and Lomefloxacin; LFLX) were compared in a murine model. in addition photostability of these compunds was studied after irradiation with long-wave UV light(UVA, 0, 0.3 1 or 3 Joule/$Cm^2$) When hairless mice(9 to 11 weeks old 19-26g) were orally administered with different dose levels of test compunds and exposed to UVA(40J/$cm^2$) inflammatory reactions were observed in a dose dependent manner. Among the compounds tested, LB20304a demonstrated the least phototoxic effects and showed no inflammatroy lesions at a dose level of 100mg.kg (Low dose). ENX and LFLX demonstrated much greater phototoxic reactions while CPFX showed similar or slightly greater phototoxic reactions compared to LB20304a. Similar to the in-vivo results the solutions of LB20304a and CPFX irradiated with UVA demonstrated reduced spectral changes compared to those of ENX and LFLX. In conclusion these data suggest that phototoxic potencies of the quinolones tested were; LFLX > ENX > CPFX $\geq$ LB20304a. No phototoxic dose of LB20304a in mice was 100 mg/kg.

• YAKHAK HOEJI
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• v.40 no.1
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• pp.102-111
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• 1996

LB10522 is a new parenteral broad spectrum cephalosporin with a catechol moiety at C-7 position of beta-lactam ring. This compound can utilize tonB-dependent iron transp ort system in addition to porin proteins to enter bacterial periplasmic space and access to penicillin-binding proteins (PBPs) which are the lethal targets of ${\beta}$-lactam antibiotics. The chelating activity of LB10522 to metal iron was measured by spectrophotometrically scanning the absorbance from 200 to 900nm. When $FeCl_3$ was added, optical density was increased between 450 and 800nm. LB10522 was more active against gram-negative strains in iron-depleted media than in iron-replete media. This is due to the increased expression of iron transport channels in iron-depleted condition. LB10522 showed a similar activity against E. coli DC2 (permeability mutant) and E. coli DCO (wild type strain) in both iron-depleted and iron-replete media, indicating a minimal permeaility barrier for LB10522 uptake. LB10522 had high affinities to PBP 3 and PBP 1A, 1B of E. coli. By blocking these proteins, LB10522 caused inhibition of cell division and the eventual death of cells. This result was correlated well with the morphological changes in E. coli exposed to LB10522. Although the in vitro MIC of LB10522 against P. aeruginosa 1912E mutant (tonB) was 8-times higher than that of the P. aeruginosa 1912E parent strain, LB10522 showed a similar in vivo protection efficacy against both strains in the mouse systemic infection model. This result suggested that tonB mutant, which requires a high level of iron for normal growth, might have a difficulty in surviving in their host with an iron-limited environment.

• Journal of the Korean Geotechnical Society
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• v.22 no.9
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• pp.23-36
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• 2006

This study presents the development of a new closed-form analytical solution for the ultimate bearing capacity of an embedded wall in a granular mass. The closed-form analytical solution consists of upper and lower bound solutions (UB and LB). The calculated values from these bound solutions were compared with the author's two-dimensional laboratory wall model loading test and finite element analysis in the plastic region. The comparison showed that ultimate bearing loads from both the model test and finite element analysis are located between UB and LB. In particular, the ultimate bearing load from LB showed good agreement with the ultimate bearing load values from both the model test and finite element analysis. However, the calculated value from the conventional empirical form subjected to plane-strain conditions was shown to be much smaller than the LB.

• Journal of Broadcast Engineering
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• v.14 no.2
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• pp.253-264
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• 2009

This paper presents an algorithm, aims at practical applications, for the high speed processing and performance enhancement of lane detection base on vision processing system. As a preprocessing for high speed lane detection, the vanishing line estimation and the optimal extraction of region of interest for lane boundary (ROI-LB) can be processed to reduction of detection region in which high speed processing is enabled. Image feature information is extracted only in the ROI-LB. Road lane is extracted using a non-parametric model fitting and Hough transform within the ROI-LB. With simultaneous processing of noise reduction and edge enhancement using the Laplacian filter, the reliability of feature extraction can be increased for various road lane patterns. Since outliers of edge at each block can be removed with clustering of edge orientation for each block within the ROI-LB, the performance of lane detection can be greatly improved. The various real road experimental results are presented to evaluate the effectiveness of the proposed method.

• Proceedings of the IEEK Conference
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• 2009.05a
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• pp.222-224
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• 2009

This paper presents an algorithm that extracts road lane's specific information by using HSI color information and performance enhancement of lane detection base on vision processing of drive assist. As a preprocessing for high speed lane detection, the optimal extraction of region of interest for lane boundary(ROI-LB) can be processed to reduction of detection region in which high speed processing is enabled and it also increases reliabilities by deleting edges those are misrecognized. Road lane is extracted with simultaneous processing of noise reduction and edge enhancement using the Laplacian filter, the reliability of feature extraction can be increased for various road lane patterns. Since noise can be removed by using saturation and brightness of HSI color model. Also it searches for the road lane's color information and extracts characteristics. The real road experimental results are presented to evaluate the effectiveness of the proposed method.