• Title/Summary/Keyword: LAD

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Coronary artery diameter of normal children aged 3 months to 6 years (생후 3개월에서 7세 미만 정상 소아에서의 관상동맥 직경)

  • Yu, Jeong Jin;Cho, Suk Kyung;Park, Yong-Mean;Lee, Ran;Chung, Sochung;Bae, Sun Hwan
    • Clinical and Experimental Pediatrics
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    • v.51 no.6
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    • pp.629-633
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    • 2008
  • Purpose : This study was designed to investigate normal domestic values for the diameter of the left main coronary artery (LCA), the left anterior descending coronary artery (LAD) and the right coronary artery (RCA). These data are necessary to define dilatation of coronary arteries in Kawasaki disease cases. Methods : Study subjects were 43 normal healthy children whose ages ranged from 3 months to 6 years. They children visited Konkuk University hospital for echocardiograph examination between March 2005 and November 2007. Measurements of coronary arterial diameters at each branch were done by off-line analyses of recorded images. Simple regression analysis of each the measurements were performed using the body size (body surface area, etc.) as the independent variable. Results : Body surface area was significantly related to the diameters of LCA ($r^2=0.20$, P=0.0038), of LAD ($r^2=0.41$, P<0.0001), and of RCA ($r^2=0.30$, P=0.0002). In the regression model, the estimates of the y-intercept were 1.703, 1.058, and 1.007; the estimates of the regression coefficient were 0.971, 1.175, and 1.177; and the estimates of the standard deviation were 0.315, 0.221, and 0.282 with respect to the three coronary arteries. Conclusion : A the linear regression model of the diameters of three coronary arteries adjusted for body surface area was produced. With these results, the Z-score calculation of the diameter of three coronary arteries, based on normal domestic data, will be possible.

Comparison of Diagnostic Accuracy for Detecting Coronary Artery Disease of Dipyridamole $^{99m}Tc$-MIBI Myocardial SPECT and It's Defect Map between Men and Women (디피리다몰 부하 $^{99m}Tc$-MIBI 심근 SPECT 극성결손지도를 이용한 관동맥질환 진단의 남녀 비교)

  • Bae, Sang-Kyun;Lee, Dong-Soo;Oh, Byung-Hee;Chung, June-Key;Lee, Myoung-Mook;Park, Young-Bae;Lee, Myung-Chul;Seo, Jung-Don;Lee, Young-Woo;Koh, Chang-Soon
    • The Korean Journal of Nuclear Medicine
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    • v.27 no.1
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    • pp.59-64
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    • 1993
  • To evaluate the usefulness and differences in diagnosing coronary artery disease (CAD) between men and women of intravenous dipyridamole $^{99m}Tc$-MIBI myocardial SPECT, we obtained $^{99m}Tc$-MIBI myocardial SPECT and compared with the findings of coronary angiographies. Ninety eight male and 37 female patients who underwent dipyridamole $^{99m}Tc$-MIBI myocardial imaging within one month of cardiac catheterization were studied. Scans were considered abnormal if perfusion defect was detected and the defect size was more than 12% for left anterior descending artery (LAD) and circumflex (LCX) and 8% for right coronary artery (RCA) territories. Lesions${\geqq}$50% luminal diameter narrowing were considered significant CAD. Overall sensitivity for detection of CAD was 94.3% in men and 96.4% in women; specificity was 70% in men and 52.6% in women (P=not significant, ns). Vessel-matched sensitivity was 75.3% in men and 72.7% in women (P=ns): specificity was 84.6% in men and 67.9% in women (P < 0.025). For individual coronary artery, the sensitivity in men and women was 87.7%, 81.8% for LAD; 78%, 83.3% for RCA and 52.2%, 46.7% for LCX (P=ns): the specificity was 80%, 40% for LAD (P<0.01), 82.5%, 68.4% for RCA, 88.9%, 86.4% for LCX (P=ns). The hemodynamic parameter after intravenous dipyridamole in men and women were significantly changed; the heart rate was increased and systolic, diastolic blood pressure was decreased. Adverse effects were reported in 58.8% of men and 72.7% in women (P=ns). The incidence of chest pain and headache were higher in women. There was no significant difference in the incidences of nausea, abdominal pain, dizziness, facial flushing, dyspnea. In conclusion, dipyridamole $^{99m}Tc$-MIBI myocardial SPECT is a safe, noninvasive test for evaluation of CAD. There was no gender difference to detect CAD, but more false-positive rate in women especially in the territory of LAD.

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Design and Evaluation of a Lung Assist Device for Patients with Acute Respiratory Syndrome using Hollow Fiber Membranes (중공사 막을 이용한 급성호흡곤란증후군 환자용 폐 보조 장치의 설계와 평가)

  • Lee, Sam-Cheol;Kwon, O-Sung;Kim, Ho-Cheol;Hwang, Young-Sil;Lee, Hyun-Cheol
    • Membrane Journal
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    • v.15 no.3
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    • pp.224-232
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    • 2005
  • The use of the lung assist device (LAD) would be well suited for acute respiratory failure (ARF) patients, combining the simplicity of mechanical ventilation with the ability of extracoporeal membrane oxygenators (ECMO) to provide temporary relief for the natural lungs. This study's specific attention was focused on the effect of membrane vibration in the LAD. Quantitative experimental measurements were performed to evaluate the performance of the device, and to identify membrane vibration dependence on blood hemolysis. We tried to decide upon excited frequency band of limit hemolysis when blood hemolysis came to through a membrane vibration action. The excited frequency of the module type 5, consisted of 675 hollow fiber membranes, showed the maximum gas transfer rate. We concluded that the maximum oxygen transfer rate seemed to be caused by the occurrence of maximum amplitude and the transfer of vibration to hollow fiber membranes. It was excited up to $25{\pm}5$ Hz at each blood flow rate of module type 5. We found that this frequency became the 2nd mode resonance riequency of the flexible in blood flow. Blood hemolysis was low at the excited frequency of $25{\pm}5$ Hz. Therefore, we decided that limit hemolysis frequency of this LAD was $25{\pm}5$ Hz.

전자지불 수단으로서의 휴대 정보통신기기의 새로운 지평

  • 황원철
    • Review of KIISC
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    • v.12 no.3
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    • pp.42-47
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    • 2002
  • 개인용 휴대 정보통신 단말이 음성 내지는 정보를 통신(transmission)하는 데서 벗어나 일상생활을 지원하는(Live Assistance Device)로 그 영역이 확장되고 있다. LAD 의 가장 유력한 초기 대상 적용 분야는 전자 지불로서 본고에서는 개인용 휴대 정보 통신 단말을 이용한 오프라인 지불의 기존 관련 산업에의 영향, 제반 관련 기술 및 business case를 살펴본다.

The ATM SAR Processor Optimized for VoDSL Service (VoDSL 서비스에 최적화된 ATM SAR 프로세서)

  • 손윤식;정정화
    • Journal of the Institute of Electronics Engineers of Korea SD
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    • v.40 no.10
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    • pp.9-16
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    • 2003
  • In this paper, we propose an ATM processor suitable for VoDSL subscriber's equipments. The processor is composed of ATM block, AAL protocol block and ATS scheduler, and provides up to 4 VCC which service data and voice traffics on the ATM network. The proposed ATS scheduler can guarantee QoS of the voice traffic and supports multiple AAL2 packet. The ATM processor is manufactured on the 0.35 micron fabrication line of HYNIX semiconductor and provides the maximum data transfer rate of up to 52 Mbps. We implement the LAD, which is the VoDSL subscriber's equipment. The experimental results on the test bed network shows that the proposed hardware scheme successfully services most of the applications of the VoDSL services.

DENTAL MANAGEMENT OF LEUKOCYTE DEFICIENCY IN A CHILD WITH SEVERE ORAL INVOLVEMENT (백혈구 접착 결핍 증후군 환아의 치과적 처치)

  • Kim, Hyun-Jin;Lee, Nan-Young;Lee, Sang-Ho
    • The Journal of Korea Assosiation for Disability and Oral Health
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    • v.3 no.1
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    • pp.26-30
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    • 2007
  • Leukocyte adhesion deficiency(LAD) is a rare autorecessive defect of phagocytic function resulting from a lack of leukocyte cell surface expression of ${\beta}_2$ integrin molecules(CD 18) that are essential for leukocyte adhesion to endothelial cells and chemotaxis. As a results, patients with LAD suffer from severe bacterial infections and impaired wound healing. A small number of patients with leukocyte adhesion deficiency-1 have a milder defect, with residual expression of CD18. These patients tend to survive beyond infancy; they manifest progressive severe periodontitis, alveolar bone loss, periodontal pocket formation, and partial or total premature loss of the primary and permanent dentitions. In this report, we report on a 7 year old girl with severe oral involvement. The most import focus should be to control infections to reduce the risk for future infection.

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Analysis of Bypass Grafting Effects in Stenosed Coronary Arteries (협착이 발생된 관상동맥에 대한 이식우회로술의 효과분석)

  • Kim, Hyoung-Ho;Suh, Sang-Ho;Lee, Jeong-Sang
    • Transactions of the Korean Society of Mechanical Engineers B
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    • v.36 no.2
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    • pp.153-159
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    • 2012
  • Bypass anastomosis is frequently adopted for surgical treatments of stenosed coronary arteries. Optimal coronary bypass grafting should be investigated to improve the patency in arterial bypass techniques. The objective of this study is to analyze the effects of Y-grafting bypasses and T-grafting bypasses for various bifurcation and anastomotic angles. In order to find the optimal geometric configuration, the hemodynamic characteristics are obtained and compared with each other for different geometries. We found that both the left anterior descending artery (LAD) and left circumflex artery (LCX) blood flows were distributed evenly when the bypass grafting angle and bifurcated angle were $30^{\circ}$ and $15^{\circ}$, respectively,.

Traumatic Coronary Artery Dissection in a Young Woman after a Kick to Her Back

  • Ipek, Emrah;Ermis, Emrah;Demirelli, Selami;Yildirim, Erkan;Yolcu, Mustafa;Sahin, Bingul Dilekci
    • Journal of Chest Surgery
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    • v.48 no.4
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    • pp.281-284
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    • 2015
  • We present the case of a 38-year-old woman admitted to our outpatient clinic with accelerating back pain and fatigue following a kick to her back by her husband. Upon arrival, we detected ST segment elevation in the D1, aVL, and V2 leads and accelerated idioventricular rhythm. She had pallor and hypotension consistent with cardiogenic shock. We immediately performed coronary angiography and found a long dissection starting from the mid-left main coronary artery and progressing into the mid-left anterior descending (LAD) and circumflex arteries. She was then transferred to the operating room for surgery. A saphenous vein was grafted to the distal LAD. Since the patient was hypotensive under noradrenaline and dopamine infusions, she was transferred to the cardiovascular surgery intensive care unit on an extracorporeal membrane oxygenator and intra-aortic balloon pump. During follow-up, her blood pressure remained low, at approximately 60/40 mmHg, despite aggressive inotropic and mechanical support. On the second postoperative day, asystole and cardiovascular arrest quickly developed, and despite aggressive cardiopulmonary resuscitation, she died.

Long Segmental Reconstruction of Diffusely Diseased Left Anterior Descending Coronary Artery Using Left Internal Thoracic Artery with Extensive Endarterectomy

  • Heo, Woon;Min, Ho-Ki;Kang, Do Kyun;Lee, Sung Kwang;Jun, Hee Jae;Hwang, Youn-Ho
    • Journal of Chest Surgery
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    • v.48 no.4
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    • pp.285-288
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    • 2015
  • In coronary artery bypass grafting, a diffusely diseased left anterior descending coronary artery (LAD) is an obstacle to achieving complete revascularization, consequently leading to the possibility of a poor prognosis. Long segmental reconstruction with or without endarterectomy is a revascularization method for treating diffusely diseased coronary arteries. Herein, we report a successful case of long segmental reconstruction of a diffusely diseased LAD using a left internal thoracic artery onlay patch after endarterectomy.