• Title/Summary/Keyword: Kyung-Ok-Go

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The Ameliorating Effect of Kyung-Ok-Go on Menopausal Syndrome Observed in Ovariectomized Animal Model (난소 절제 동물모델을 이용한 경옥고의 갱년기 증후군 개선 효과)

  • Cho, Kyungnam;Jung, Seo Yun;Bae, Ho Jung;Ryu, Jong Hoon
    • Korean Journal of Pharmacognosy
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    • v.51 no.4
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    • pp.310-316
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    • 2020
  • Kyung-Ok-Go (KOK) is a traditional prescription used for debilitating natural aging and post-illness debilitation. KOK has been used in a variety of ways because it strengthens immunity, prevents illness, and helps recovery in case of illness. In particular, recent research has revealed that KOK helps improve memory and cognition. Therefore, in this study, we investigated whether KOK was effective in improving memory decline and depression-state observed during menopause. In the present study, we employed ovariectomized mouse as an animal model for measuring menopausal syndrome. The administration of KOK for 8 weeks, the object recognition memory and working memory were improved in novel object recognition test and Y-maze test. And in the forced swimming test, the immobility time were decreased. Additionally, the expression level of mature brain derived neurotropic factor (mBDNF) was increased by KOK administration in ovariectomized mouse hippocampus. These results suggested that KOK could improve cognitive decline and depression during menopausal period, and it might be come from enhancing expression level of mBDNF in hippocampus.

Layer-by-layer assembled graphene oxide films and barrier properties of thermally reduced graphene oxide membranes

  • Kim, Seon-Guk;Park, Ok-Kyung;Lee, Joong Hee;Ku, Bon-Cheol
    • Carbon letters
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    • v.14 no.4
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    • pp.247-250
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    • 2013
  • In this study, we present a facile method of fabricating graphene oxide (GO) films on the surface of polyimide (PI) via layer-by-layer (LBL) assembly of charged GO. The positively charged amino-phenyl functionalized GO (APGO) is alternatively complexed with the negatively charged GO through an electrostatic LBL assembly process. Furthermore, we investigated the water vapor transmission rate and oxygen transmission rate of the prepared (reduced GO $[rGO]/rAPGO)_{10}$ deposited PI film (rGO/rAPGO/PI) and pure PI film. The water vapor transmission rate of the GO and APGO-coated PI composite film was increased due to the intrinsically hydrophilic property of the charged composite films. However, the oxygen transmission rate was decreased from 220 to 78 $cm^3/m^2{\cdot}day{\cdot}atm$, due to the barrier effect of the graphene films on the PI surface. Since the proposed method allows for large-scale production of graphene films, it is considered to have potential for utilization in various applications.

The Essential Oils of Ligusticum tenuissimum Roots (고본뿌리의 정유성분)

  • Yook, Chang-Soo;Kang, Chan-Koo;Inn, Mun-Kyo;Kim, Kyoung-Ok;Kim, Chong-Woo
    • YAKHAK HOEJI
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    • v.41 no.2
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    • pp.273-276
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    • 1997
  • Ligusticum tenuissimum belongs to Umbelliferae, and its root is generally used in headache, common cold and arthralgia L. We have extracted and isolated butylidene phthal ide, 3-butylidene-4,5-dihydrophthalide of phthalide group and l-limonene, etc. of terpenoid group from the root by ordinary method. In Ligusticum sinense, L. jeholense, L. tenuissimum, L. jeholense var. tenuisectum, and L. officinale etc., the components of cnidilide, ligustilide of phthalide group are common features and specific constituents in genus Ligusticum. Therefore comparing that there is no phthalide group in genus Angelica, we think it is able to classify the difference of genus between Ligusticum and Angelica of Umbelliferae in chemotaxonomy.

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A study on the Transformation Process of Traditional Small City Structure in Jeollabuk-Do (근대(近代) 도시화(都市化)에 따른 전라도(全羅道) 전통(傳統) 소도읍(小都邑)의 공간구조변화과정(空間構造變化過程) 연구(硏究))

  • Lee, Kyung-Chan
    • Journal of architectural history
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    • v.11 no.3 s.31
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    • pp.21-34
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    • 2002
  • This study is to analyse the transformation process of spatial structure of traditional small city structure in Jeollabuk-Do in the process of modern urbanization between 19th century and the year 2000. The small cities, IM-PI, YONG-AN, YEO-SAN, OK-GOO, GO-SAN, MU-JANG, GUM-MA, GO-BU, which have been local administrative center in CHO-SUN dynasty, have role of local administrative center of subdivision of country-myon, except OK-GOO. The method of this study is to investigate the transformation process of spatial structural elements of with the actual field surveys, the analysis of Gunhyun map made in 1872, land registration maps in 1910s and 2000, and various topological maps. The elements of analysis are the topological site and geographical situation conditions, the urbanized areas, the street systems, the function of streets, the focal points of urban land use, the land use systems, and the location of major facilities such as administration facilities, markets, bus terminals. The analytical point of view and the results are as follows. There is strong relationship between the transformation of internal matrix route system and the growth pattern of urbanized areas, Especially on the contrary to the matrix route with East-West direction which has the role of checking the growth of urbanized area, the South-North direction route acts as the leading line of the growth. The focal points structure of urban land use shows transformation process from the point of central space of administrative district in front of Nae-A, to the access point to administrative district or to the access point to housing and neighborhood commercial area. From the point of functional area structure and major facilities location, line-type commercial area is developed along the line of central axis route and access route to administrative district. Especially direction of the growth of commercial area is strongly connected with the interrelationship between the study area and its neighboring cities. Pattern of commercial district development is varied with the direction of matrix route. That is, commercial district, which shows one side development pattern along the East-West direction route, is developed on both sides of street along the South-North direction route.

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A Study on Mordern Hanbok Design Applied by the Costume in Koguryo Mural Painting (고구려 고분벽화의 복식을 응용한 현대 한복 디자인 연구)

  • Kim, Ok-Soon;Jin, Kyung-Ok
    • Fashion & Textile Research Journal
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    • v.8 no.2
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    • pp.161-167
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    • 2006
  • The purpose of this research are to identify the nature of artistic beauty of Kokuryeo dresses and to apply the artistic beauty, formative uniqueness, and esthetic value of Kokuryeo in the modern Korean dress design for creation of new designs. Significance of this research lies in the fact that beauty of traditional dresses possesses highly valuable importance for application to modern fashion design processes. Kokuryeo dresses basically comprised of Yu, Sang, Go and Po, and contains within abstract beauty along with emphasis on geometric elements like dots, lines, and surfaces. Red, Black, Violet, Verdant and scarlet colors were moderately used against the mainly white canvas, and different colors were often used for the top and the bottom. Silk, Hemp cloth and Wool were used for different social levels or ranks, and from the wide variety of colors and patterns of the dresses, such as Round-patterns, Cloud-patterns and Vine-patterns, worn by the people illustrated on the wall paintings, it appears that various materials were used. Vertical hems, Yu (shirts), Sang (skirts), noblemen's dresses, kings' dresses, etc. from Kokuryeo tomb wall paintings were applied, and various dying methods, natural materials and sewing methods were used to recreate the unique features of Kokuryeo dresses in modern designs in an attempt to recreate the esthetic value of Kokuryeo dresses.

An Efficient Method for Synthesis of PEO-Based Macromonomer and Macroinitiator

  • Kim, Jung-Ahn;Choi, Song-Yee;Kim, Kyung-Min;Go, Da-Hyeon;Jeon, Hee-Jeong;Lee, Jae-Yeol;Park, Hyeong-Soo;Lee, Cheol-Han;Park, Heung-Mok
    • Macromolecular Research
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    • v.15 no.4
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    • pp.337-342
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    • 2007
  • The n-butyllithium-initiated ring-opening polymerization of ethylene oxide, in a mixture of benzene and dimethylsulfoxide (DMSO), between $25-45^{\circ}C$, with potassium tert-butoxide, is a useful and powerful method to control the molecular weight as well as achieve a quantitative chain-end functionalization yield of the resulting polymeric alkoxide via a one pot synthesis. The molecular weight of the product could be controlled by adjusting the ratio of grams of monomer to moles of initiators, such as n-butyllithium ([n-BuLi]) and potassium t-butoxide ([t-BuOK]). The yields for the macromonomer and ${\omega}-brominated$ poly(ethylene oxide) (PEO) were quantitative in relation to the chain-end functionalizations of the polymeric alkoxide formed. The resulting products were characterized by a combination of $^1H-NMR$ spectroscopic and size exclusion chromatographic analyses.

A Study on Jin Jeung Ga Jeung Byun of the Byun Jeung Ok Ham(辨證玉函) (변증옥함(辨證玉函) 권사(卷四) 진증가증변(眞症假症辨)에 대(對)한 연구(硏究))

  • Seo, Jong-Chul;Park, Dong-Seok;Keum, Kyung-Soo
    • Journal of the Korean Institute of Oriental Medical Informatics
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    • v.16 no.2
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    • pp.9-49
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    • 2010
  • Byun Jeung Ok Ham, written by Jin Sa Tak is composed of four books. This book is estimated of being written after A.D 1688 and composed of internal medicine, obstetrics and gynecology, ophthalmology, dental surgery and so on, total 36 parts of clinical medicine. This is the last book of that four studying about definition on true and false of 15 diseases. 15 subjects follow, tumo, heat, faint, hematemesis and nosebleeding, insanity, great vomiting, great diarrhea, great thirst, scrotal hernea, uterus attacked by heat, dysentery, congestion, great swelling, malaria, attack by cold. This treatise is the last book of four which deals with jin ga translating into korean and studying about medical theories. In every parts, author's unique clinical theory appears affluently and in that periods his study developed a lot in those days' medical methods. The first book deals with eum yang. second book is weakness and strongness, third upper and low, fourth truth and untruth. First book, Jin Sa Tak says studying on eum yang is oriental medical basic theory and on incurable diseases or chronic symptoms, doctor must go back to that eumyang demonstration after can cure patients. Second parts are on weakness and strongness demonstration, that weakness is weakness of patients' energy and strongness is prosperous condition of diseases' attack. Third parts are on upper and low, that upper is upper parts of human body of painful parts and low is human low parts of pain, that is parts of under waist. And this treaties fourth parts are truth and untruth, true symptoms and untrue symptoms, that is the real reaction of human condition and the other way. Every prescriptions are author's creations. This book provides new viewpoints which surpasses original ancient medical theories. Author suggests new opinions about chronic and incurable diseases.

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Perimenstrual Discomforts, Coping and Relief of Symptoms in Female Workers (일부 근로여성이 호소하는 월경전후기 불편감, 월경대처 및 증상완화 정도에 관한 연구)

  • Sung Mi-Hae;Min Kyung-Ok;Jang Youn-Jeong;Jeon Ju-Yeon
    • Journal of Korean Public Health Nursing
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    • v.20 no.1
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    • pp.57-68
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    • 2006
  • Purpose: To identify perimenstrual discomforts, coping and relief of symptoms in female workers. Methods: A convenience sample of 203 women who had worked were obtained from two hospitals in Busan. Data were collected through questionnaires from November 8 to 16, 2004. Three instruments were used in this study: the Perimenstrual Discomfort Questionnaire by Park(1988) and the Menstrual Coping Questionnaire and the Relief of Symptoms by Billings & Moos(1981) modified for this study. The data were analyzed by descriptive statistics, t-test, and ANOVA with SPSS 10.0 program. Results: The prevalence rate of dysmenorrhea was 81.3%. The total mean score for perimenstrual discomforts was 2.83 out of a possible total of 5 and the mean score for each category was, 3.08 for water retention, 2.95 for pain, 2.88 for negative affect, 2.83 for behavioral change, 2.73 for autonomic reactions, and 2.51 for concentration. According to these study results, statistical differences were found for age(F=2.76, p=0.04), feeling to menstruation(F=3.94, p=0.00), dysmenorrhea(t=4.26, p=0.00), and taking medication(t=2.09, p=0.00). The coping modes with the highest scores were 'take a hot bath'(99.0%)', 'rest and go to bed'(83.7%), 'regard menstruation as a physiological and temporary phenomenon'(76.8%), 'take a warm shower'(65.0%). The most frequently used methods to relieve symptoms were 'rest and go to bed'(70.0%), 'take a warm shower'(57.6%), 'take pain killers'(49.8%), 'apply hot water bag on painful parts of the body'(46.8%). Conclusion: Further research is needed to understand perimenstrual discomforts and the variables associated with them. Nursing intervention has to be considered in any program aiming to reduce perimenstrual discomforts.

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A Phenomenological Study on Dysmenorrhea Experience of Women (여성의 월경통 경험에 대한 현상학적 연구)

  • Ham, Mi-Young;Han, Kyoung-Soon;You, Soo-Ok;Park, Kyung-Sook
    • Women's Health Nursing
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    • v.5 no.2
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    • pp.288-299
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    • 1999
  • The purpose of this research was to understand the dysmenorrhea experience of women. To do this work, we asked 9 women a lot of questions about dysmenorrhea. The interviews were carried out from JUL 1, 1998 through JUL 30, 1998. They were audio-recorded and analyzed using Van kaam's Phenomenological method. Results were as follows. One hundreds forty two descriptive expression were found and they were grouped under twenty common factors. twenty common factors were grouped under six higher categories. Two common factors, "Physical pain", "Physical Discomfort" were grouped under . Three common factors, "Receptively of Femininity", "Women's Persecution", "Mystery of Femininity" were grouped under . Three common factors, "Emotional Anxiety", "Disgust of Pain", "Solitude" were grouped under . Two common factors, "Coping with Pain Relief", "Fear of Pain relief method" were grouped under . One common factors "Beauty" were grouped under , One common factors, "Singularity" were grouped under . As Dysmenorrhea Experience of Women's authors recommend further studies on Women's Dysmenorrhea Experience and go into details nursing intervention of Dysmenorrhea relief method.

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Model Construction of Sexual Adjustment of Patients with Spinal Cord Injury (척수장애인의 성적적응과 관련요인에 관한 모형구축)

  • Kang, Hyun-Sook;Koh, Jung-Eun;Shu, Yeon-Ok
    • Journal of Korean Academy of Nursing
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    • v.30 no.4
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    • pp.1018-1034
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    • 2000
  • The purpose of this study was to construct model of sexual adjustment in people with spinal cord injury and to determine factors that relate to sexual adjustment using methodological triangulation. A total of 134 persons who were registered members of spinal cord injury organization and admitted rehabilitation unit in the hospital were included in the study. Participants answered questionnaire concerning importance of life events, sexual concern, sexual adjustment. Qualitative data were collected through semi-structured indepth interviews from 10 individuals with spinal cord injury who were previously included in the quantitative study. Constant compatative method was used to analyze the data. The results were as follows : 1) With respect to eleven other areas of life, sex life ranked the sixth and economic status ranked the highest in terms of importance. However social life ranked the lowest among the 11areas. 2) Among seven topics related to sexuality were methods and techniques to achieve sexual satisfaction, and helping a partner cope emotionally with limitation on sexual dysfunction was the second greastest. 3) The mean score for sexual adjustment was 19.47 which can be considered. 4) A process on how individuals with spinal cord injury adjust to their changed sexual life immerged from the qualitative data. It includs 4 stages: 'stage of loss' 'stage of endeavoring' 'stage of effort' and 'stage of adjustment'. Categories showing context for the action/interaction strategies were 'steadiness' and 'rediscovery as a sexual being'. There were three factors which may stimulate the adjustment process while the others may interrupt it. Those factors included personal matters, family matters and social matters. The individuals may follow each stage step by step but may go back to the previous step depending on the outcomes of their adjustment. 5) There were three factors which may stimulate the adjustment process while the others may interrupt it. Those factors included personal matters, family matters and social matters.

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