• Title/Summary/Keyword: Kwan Soo Lee

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Antioxidant Compounds and Antioxidant Activities of the 70% Ethanol Extracts from Brown and Milled Rice by Cultivar (벼 품종별 현미와 백미 70% 에탄올 추출물의 항산화 성분 및 항산화 효과)

  • Kim, Dae-Jung;Oh, Sea-Kwan;Yoon, Mi-Ra;Chun, A-Reum;Hong, Ha-Cheol;Lee, Jun-Soo;Kim, Yeon-Kyu
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.39 no.3
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    • pp.467-473
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    • 2010
  • The objectives of this study were to determine various bio-active components from some brown rice and milled rice of some cultivars, as well as to assess their contribution to the radical scavenging linked-antioxidant activity. DPPH or ABTS radical scavenging activities, and reducing power have been used to investigate the relative antioxidant activities of 70% ethanol extracts. The contents of total polyphenol, total flavonoid, $\gamma$-oryzanol, and vitamin E in the extracts were also measured by spectrophotometric methods or HPLC. The antioxidant components and antioxidant activities of 70% ethanol extracts from brown rice were higher than those from milled rice. In addition, our results showed that the high level of antioxidant compounds was found in brown rice of Hongjinju, and the antioxidant activities of the 70% ethanol extracts from pigmented brown rices, such as Hongjinju and Heugkwang, were comparably higher than the others.

Economic Analysis of Geothermal Energy and VMD Desalination Hybrid Process (지열에너지와 진공 막 증류법을 활용한 해수담수화 연계형 공정의 경제성 분석)

  • Park, Kiho;Kim, Jin Hyun;Kim, Hyuk Soo;Lee, Kwan-Young;Yang, Dae Ryook;Kim, Kyung Nam
    • Clean Technology
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    • v.20 no.1
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    • pp.13-21
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    • 2014
  • Because of the water scarcity caused by the increase of salinity in the underground water, seawater desalination stands out as one of the most promising solution. As there are so much energy costs in operating desalination plants, new hybrid process which is more effective should be researched. A geothermal VMD (vacuum membrane distillation) hybrid process is a competitive alternative for seawater desalination. Because geothermal energy has significant characteristics of high capacity factor to operate the power plant at full capacity for 24 hour per day, it can be a priority heat source of VMD superior to any other renewable energies such as solar and wind power. In this study, we design a geothermal VMD hybrid process, analyze it economically and finally compare the result with a case of conventional VMD process. Geothermal VMD hybrid process generates $23,822,409 of NPV (net present value) more than the conventional VMD process in case of 5% discount rate. The break-even point between these processes is 5.36 year. Sensitivity analysis indicates that steam cost is the most decisive influence variable to the economic outcome.

Site Responses of Japanese Stations Near the Epicenter and Korean Stations for the Fukuoka Earthquake (후쿠오카 지진 ('05. 3. 20, $M_{JMA}=7.0$)에 대한 일본 인근 지진관측소와 국내 지진관측소의 주파수응답특성 비교)

  • Yun, Kwan-Hee;Park, Dong-Hee;Chang, Chun-Jung;Choi, Weon-Hack;Lee, Dae-Soo
    • Journal of the Korean Geophysical Society
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    • v.8 no.1
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    • pp.15-21
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    • 2005
  • The apparent source spectrum of the Fukuoka earthquake is estimated at the seismic basement by removing from the observed spectra at Korean seismic stations the path and site responses that were previously revealed through inversion process applied to large spectral D/B accumulated until 2004. The approximate source spectrum is also estimated by using data recorded near the epicenter from various Japanese seismic networks and compared with the Korean source spectrum. The comparison result shows that there is good agreement among source spectra estimated based on the data from seismic networks of Korea at large distances (190 km

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Hygienic State and Awareness of Drink Vending Machines in a City (중소도시 지역의 음료 자동판매기에 대한 위생 실태 및 인식)

  • Park, Ji-Hyuk;Lim, Hyun-Sul;Kim, Sang-Kyu;Park, Byeong-Chan;Lee, Kwan;Kim, Hee-Soo
    • Journal of agricultural medicine and community health
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    • v.34 no.2
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    • pp.168-174
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    • 2009
  • Objective: This study was conducted to investigate the hygienic state and awareness of drink vending machines in a city. Methods: Twelve of the most frequently used vending machines in various areas were selected in October 2008. As soon as fresh samples of milk coffee and adlay tea were collected in sterile containers from each machine, the temperature was measured. The samples were carried on ice to the laboratory to test total plate counts and Escherichia coli contamination. College students were inquired about drink vending machine hygiene by implementing self-developed questionnaires. Results: The temperature of 6 milk coffee samples (50.0%) and 8 adlay tea samples (66.7%) turned out to be inadequate. The total plate counts of milk coffee samples were all adequate, although 9 adlay tea samples (75.0%) were inadequate. All the beverage samples were negative for E. coli. In questionnaires obtained from 74 users of coffee vending machines, only 2 (2.7%) expected the hygienic state of vending machines to be good. There were 27 people (33.3%) that knew the existence of hygiene-related laws for vending machines. Conclusions: This study reveals that the hygienic state of drink vending machines insufficiently reaches the standard for the hot beverage and that most people are not aware of importance of vending machine hygiene. It is necessary to make improvement in the hygiene of vending machines and public awareness in this city.

A Case of Cryptococcosis involving Lung and CNS without Underlying Disease (폐와 중추신경계를 침범한 효모균증(Cryptococcosis) 1예)

  • Lee, Min-Su;Park, Sang-Seon;Koh, Young-Il;Jang, An-Soo;Lim, Sung-Chul;Yang, Ju-Yeoul;Park, Hyung-Kwan;Na, Hyun-Joo;Kim, Young-Chul;Choi, In-Seon;Park, Kyung-Ok
    • Tuberculosis and Respiratory Diseases
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    • v.42 no.4
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    • pp.618-623
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    • 1995
  • Cryptococcosis is a systemic mycosis that most often involves the lungs and central nervous system and, less frequently, the skin, skeletal system, and prostate gland. Cryptococcus neoformans, the causative organism, is a yeastlike round or oval fungus, 4 to $6{\mu}m$ in diameter, which is surrounded by a polysaccharide capsule and reproduces by budding and found in soil and other environmental areas, especially those contaminated by pigeon droppings. Humans and animals acquire infection after inhalation of aerosolized spores. Condition or factors that predispose to cryptococcosis include corticosteroid therapy, lymphoreticular malignancies, HIV infection, and sarcoidosis etc. We discribed a case of cryptococcosis involving lung and CNS coincidently without specific underlying disease and the literature on subject were reviewed. A fifty-six year-old previously healthy female presented with headache of 3 months of duration. She had no history suggesting immunologic suppression and we could not find any abnormal laboratory findings including blood sugar, serum immunoglobulin and complement level, HIV antibody, and T cell subsets. Chest roentgenogram and CT scan showed a solitary soft tissue mass in LUL with distal pneumonitis. Brain MRI showed granulomatous lesion in cerebellum and parasagittal cortex of right frontal lobe. The diagnosis was made by bronchoscopic brushing cytology, transthoracic fine needle aspiration, and sputum KOH mount and culture. She was treated 6 weeks course of Amphotericin B and switched to oral fluconazole therapy for 3 months. Her symptoms and X-ray findings were improved gradually and she is now under regular clinical follow up.

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Inhibition of Intimal Hyperplasia by Perivascular Delivery of Paclitaxel Using Poly(n-butylmethacrylate) or Poly(3-hydroxybutyrate-co-4-hydroxybutyrate) in Balloon-Injured Rat Carotid Arteries (쥐 경동맥 손상 모델에서 Poly(n-butylmethacrylate) 혹은 Poly(3-hydroxybutyrate-co-4-hydroxybutyrate)를 이용한 Paclitaxel 국소 전달 요법의 신생내막 형성 억제 효과)

  • Kwon, Jin-Sook;Lee, Ho-Yeon;Heo, Shin-Haeng;Park, Rho-Kwan;Shim, Tae-Jin;Kim, Yu-Kyug;Kim, Beom-Soo;Kim, Dong-Woon
    • Polymer(Korea)
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    • v.32 no.3
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    • pp.284-289
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    • 2008
  • Polymer is a critical component of local drug delivery to prevent restenosis. This study tested whether poly(n-butylmethacrylate)(PBMA) and poly(3-hydroxybutyrate-co-4-hydroxybutyrate)(PHA) was candidates for this purpose. In vitro release of paclitaxel from PBMA and PHA loaded with 10% paclitaxel exhibited a triphasic release profile, with a fast initial and intermediate second phase followed by a slow release phase. Perivascular delivery of paclitaxel using these films inhibited neointimal hyperplasia in balloon-injured rat carotid arteries. The paclitaxel-loaded PBMA or PHA groups showed significant neointimal formation reductions versus the control groups (PBMA vs control: $0.03{\pm}0.02$ vs $0.10{\pm}0.01\;mm^2$, p<0.05; PHA vs control: $0.04{\pm}0.03$ vs $0.09{\pm}0.01\;mm^2$, p<0.05). This study suggests that PBMA and PHA could be good candidate polymers of local drug delivery to prevent restenosis. Perivascular delivery using these films represents a possible approach for prevention of restenosis. These can be candidate polymers for drug eluting stents.

Antimicrobial, Antihypertensive and Anticancer Activities of Medicinal Herbs (생약재의 항균, 항고혈압 및 항암 활성)

  • Do, Jeong-Ryong;Kim, Ki-Ju;Jo, Jin-Ho;Kim, Young-Myoung;Kim, Byeong-Sam;Kim, Hyun-Ku;Lim, Sang-Dong;Lee, Soo-Won
    • Korean Journal of Food Science and Technology
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    • v.37 no.2
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    • pp.206-213
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    • 2005
  • Antibacterial, antifungal, anticancer and angiotensin-converting enzyme (ACE) inhibitory activities of water and 70% ethanol extracts of 32 medicinal herbs species were investigated. Terminalia chebula extracts showed strong antibacterial activities. Ethanol extract of Cinnamomum cassia showed good antifungal activity. ACE inhibitory activities or P. corylifolia water extract and Fraction I of P. corylifolia water extract were 65.2 and 81.8%, respectively. Cytotoxicity of ethanol precipitate fraction obtained from water extract of Eugenia caryophyllata was highest.

Genome-based Gene Expression Analysis of EGCG-mediated Cell Transformation Suppression Effect in Mouse Cell line Balb/c 3T3 A31-1-1 (마우스세포주 Balb/c 3T3 A31-1-1에서 Epigallocatechin gallate(EGCG)의 세포암화 억제효과에 대한 유전자발현 해석)

  • Jung, Ki-Kyung;Suh, Soo-Kyung;Kim, Tae-Gyun;Park, Moon-Suk;Lee, Woo-Sun;Park, Sue-Nie;Kim, Seung-Hee;Jung, Hai-Kwan
    • Environmental Mutagens and Carcinogens
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    • v.26 no.4
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    • pp.125-132
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    • 2006
  • Previous studies showed that epigallocatechin gallate(EGCG) have substantial effects of suppressing the N-methyl-N'-nitro-N-nitrosoguanidine(MNNG)-initiated cell transformation process on the bases of foci formation frequency and loss of anchorage dependency. In this study we tried to clarify the molecular mechanism of suppressing the cell transformation process. Mouse cell line balb/c 3T3 A31-1-1 was exposed 2 days to MNNG followed by 15 days 12-O-tetradecanoylphorbol-13-acetate(TPA) treatment for our transformation process. EGCG was added after the time point of 24 hours exposure to TPA and incubated for 19 days. 2029 genes were selected in our transformation process that showed fold change value of 1.5 or more in the microarray gene expression analysis covering the mouse full genome. These genes were found to be involved mainly in the cell cycle pathway, focal adhesion, adherens junction, TGE-$\beta$ signaling, apoptosis, lysine degradation, insulin signaling, ECM-receptor interaction. Among the genes, we focused on the 631 genes(FC>0.5) reciprocally affected by EGCG treatment. Our study suggest that EGCG down-regulate the gene expressions of up stream signaling factors such as nemo like kinase with MAPK activity and PI3-Kinase, Ras GTPase and down stream factors such as cyclin D1, D2, H, T2, cdk6.

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Changes in Contents of Nutritional Components and Eating Quality of Brown Rice by Pericarp Milling (과피층 제거에 따른 현미의 이화학특성 및 현미밥의 식감변화)

  • Kim, Hye-Won;Oh, Sea-Kwan;Kim, Dae-Jung;Yoon, Mi-Ra;Lee, Jeong-Heui;Choi, Im-Soo;Kim, Yeon-Gyu;Cha, Kil-Nam
    • KOREAN JOURNAL OF CROP SCIENCE
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    • v.57 no.1
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    • pp.35-40
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    • 2012
  • In this study, the effect of degree of milled wax layer on compositions (protein and total dietary fiber content), Alkali Digestion Value (ADV), and texture (hardness, stickiness, toughness, and adhesiveness) with brown rice was investigated. For all the rice cultivars, $Baegjinju$, $Keunnun$, $Samkwang$, and $Seolgaeng$, protein content decreased significantly as the degree of pericarp milling increased ($p$<0.05). Total dietary fiber (TDF) content for $Keunnun$ (9.56%${\rightarrow}$8.09%) and $Samkwang$ (8.05%${\rightarrow}$7.06%) significantly decreased with the degree of removed wax layer. ADV was not affected by being removed wax layer, but ADV of $Samkwang$ was increased from 3.56 to 6.78. As the degree of removed wax layer increased (0%${\rightarrow}$10%), hardness and toughness of cooked brown rice were decreased but stickiness and adhesiveness was increased. The ratio of adhesiveness to hardness was increased with decreased wax layer of brown rice. Accordingly, It suggests that the regulation of the wax layer with brown rice was effected texture of cooked brown rice. The milling technology in wax layer of brown rice is that might be thought to be very useful in rice processing industry.

Effects of Ammonia Loading on Nitrification and Nitrite Build-up in an Activated Carbon Fluidized Bed Biofilm Reactor (암모니아 부하가 활성탄 유동상에서의 질산화 및 아질산 축적에 미치는 영향)

  • Choi, In-Cheol;Park, Soo-Young;Lee, Kwan-Yong;Bae, Jae-Ho;Cho, Kwang-Myeung
    • Journal of Korean Society of Environmental Engineers
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    • v.22 no.1
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    • pp.53-60
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    • 2000
  • The effects of ammonia loading on nitrification, especially on nitrite build-up, in an activated carbon fluidized bed reactor were investigated by increasing the ammonia loading rate stepwise from 0.1 to $7.5kg\;NH_3-N/m^3{\cdot}day$. Although effluent nitrite concentration and nitrification efficiency fluctuated at the loading rates above $1.8kg\;NH_3-N/m^3{\cdot}day$, an average nitrification efficiency of 90% was achieved. Nitrite build-up began at an ammonia loading rate of $l.8kg\;NH_3-N/m^3{\cdot}day$, at which the free ammonia concentration was estimated to be above 1 mg/L. During the nitrite build-up, the ratio of influent $NH_3-N$ concentration to the DO concentration of the reactor liquor and the ratio of effluent $NH_3-N$ concentration to the DO concentration of the reactor liquor was measured to be above 100 and 2, respectively. Considering the advantages of nitritation/denitrification, a fluidized bed reactor could be an effective means for biological nitrification of wastewaters with high ammonia concentration.

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