• Journal of the Korea Society of Computer and Information
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• v.25 no.7
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• pp.175-182
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• 2020

Fisher's classical method for combining independent p-values from continuous distributions is widely used but it is known to be inadequate for combining p-values from discrete probability distributions. Instead, the discrete analog of Fisher's classical method is used as an alternative for combining p-values from discrete distributions. In this paper, firstly we obtain p-values from discrete probability distributions associated with multi-sample location test data (Fisher-Pitman test and Kruskall-Wallis test data) by permutation method, and secondly combine the permutaion p-values by the discrete analog of Fisher's classical method. And we finally compare the combined p-values from both the discrete analog of Fisher's classical method and Fisher's classical method.

• Analytical Science and Technology
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• v.24 no.1
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• pp.38-44
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• 2011

The quality of decoction water would be important for the preparation of herbal medicines. Four types of decoction water, S1, S2, S3 and S4, three types of mineral water from Jeju island and one type of tap water from Seoul region were evaluated. The contents of minerals in decoction water were analysed by ICP-AES and ICP-MS. There was significant difference in the mineral contents between the types of decoction water. The bioactive components from rhubarb were extracted with four types of water and the relationship between mineral contents in water and the extracted amounts of components was evaluated. The total extraction was calculated by evaporating water and weighing the residue. The bioactive components in rhubarb were determined by HPLC method. Kruskall-Wallis rank sum tests were used. Multiple factor analysis was used to analyze the relation between the contents of mineral and total extraction or bioactive components in the decocted solutions. Not only the total extraction but also the amount of extracted bioactive components showed statistically significant relationship with the contents of minerals and anions in decoction water.