• 생물정신의학
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• 제14권1호
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• pp.48-54
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• 2007

Objectives : This study aimed to examine the relationship between behavioral and psychological symptoms of dementia(BPSD) and patient and caregiver QOL in Alzheimer's disease(AD). Methods : Fifty-one AD patients and their caregivers participated. Measures about patients were Neuropsychiatric Inventory(NPI), Korean version of QOL-Alzheimer's Disease(KQOL-AD), Activities of Daily Living(ADL), Clinical Dementia Rating(CDR), and Korean version-Mini Mental State Examination(K-MMSE). Caregiver QOL was assessed with KQOL-AD and General Health Questionnaire/Quality of Life-12(GHQ/QOL-12). Results : Patient QOL-AD on patient ratings was negatively correlated with appetite/eating change and NPI scores. Patient QOL-AD on caregiver ratings was negatively correlated with hallucinations, depression/dysphoria, and NPI scores. Caregiver QOL assessed by the GHQ/QOL-12 was negatively correlated with agitation/aggression, depression/dysphoria, and NPI scores and was negatively correlated with distress related to agitation/aggression, depression/dysphoria, and NPI scores. Conclusion : BPSD of AD patients was associated with low QOL of both patients and caregivers. Thus, interventions of BPSD were needed to improve both patient and caregiver QOL.

• 대한물리치료과학회지
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• 제9권2호
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• pp.7-16
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• 2002

This study was conducted to assess the changes in the functional levels of affected upper extremities after treating hemiplegic patients by applying constraint-induced movement therapy(CIMT). The subjects were selected from 20 hemiplegic patients with scores of 25 or more in Mini Mental State Examination(MMSE-k), transferred to the departments of physical therapy in two university hospitals in Busan from December, 2001 to march, 2002, and were divided into two groups. Eleven subjects with fixing unaffected arms by CIMT were assigned to the experimental patient group and the other 9 patients to control group without fixing unaffected arms. The function of upper arms for both groups were evaluated by using Actual Amount of Use Test(AAUT) and Motor Active Log(MAL) before and after physical therapy. The malts were as follows: The recovery rates of upper extremity by AOU(Activity of Use) and QOM(Quality of Movement) were 23.9% and 27.3% for CIMT treated group, and by 8.3% and 4.6% for the control group on the average, respectively, in AAUT after physical therapy, showing statistically significant differences between two groups. And in MAL, the average recovery rates were 27.3% by AOU and 22.6% by QOM for CIMT treated group while 3.1% by both AOU and QOM for the control group, and were significantly different between twogroups.

• 재활간호학회지
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• 제20권1호
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• pp.33-41
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• 2017

Purpose: This study is a descriptive study to analyze the relationship between the cognitive function, body image and pain, and the influencing factors on the daily life performance of brain injured patients. Methods: The study subjects were 119 inpatients with brain injury who gave informed consent. The activities of daily living (ADLs), cognitive function, pain and body image were measured by Modified Barthel Index (K-MBI), K-MMSE (Mini-Mental State Examination), Visual Analog Scale (VAS), Semantic Differential Method (SDM), respectively. Results: ADLs was significantly associated with body image, cognitive function, and pain. Multiple regression analysis showed that paralysis, consciousness, cognitive function, and pain were significant factors influencing ADLs. Overall, approximately 48% of total variability in the ADLs could be explained by the 4 variables ($R^2=.477$, p<.001). Conclusion: To improve ADLs of brain injury patients, a deeper understanding of paralysis, consciousness, cognitive function, and pain of patients is required and active nursing invention should be conducted.

• 기본간호학회지
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• 제18권2호
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• pp.177-185
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• 2011

Purpose: To examine the effects of Tai Chi exercise (TCE) on muscle strength, flexibility of low extremities, postural balance and cognition in patients with Parkinson disease (PD). Method: A nonequivalent control-group pre and post-test design was used. Of the 30 participants 15 were assigned to the experimental group and 15 to the control group. The experimental group participated in 8 weeks of TCE which included one day of exercise with instructor on site and 3 days of self-exercise at home guided by a videotape. Results: The 8 weeks of TCE were found to be significantly effective in enhancing strength of low extremities, flexibility of ankles and shoulders, time of tandem stand with eye closed and level on the K-MMSE (Korean mini mental state examination). Conclusion: These results suggest that TCE has positive effects on physical fitness and cognition in patients with PD. Research over an extended period with the TCE intervention is recommended to identify further effects.

• 대한물리의학회지
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• 제7권2호
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• pp.149-155
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• 2012

Purpose : The purpose of this study was to analyze the correlations among bone mineral density(BMD), serum lipid levels, and cognitive function in the elderly with dementia. Methods : We recruited seventy elderly with dementia(men=35, women=35) to participate in the Korean mini mental state examination(K-MMSE). Their T-scores and serum lipid levels were analyzed for correlation analysis. Results : The results of this study showed that there are significant correlations between cognitive function and three factors BMD, low-density lipoprotein cholesterol(LDL-C) level, and total cholesterol(TC) level. The cognitive function scores increased proportionally with BMD but were inversely proportional to LDL-C and TC levels. There were no significant relations among cognitive function, high-density lipoprotein cholesterol(HDL-C) level, and triglyceride(TG) level. Conclusion : These results indicate that there is a direct proportionality between cognitive function and BMD and inverse proportionalities between cognitive function and LDL-C level and between cognitive function and TC level. Therefore, these levels can be indices for preventing and predicting dementia.

• 성인간호학회지
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• 제20권5호
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• pp.675-684
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• 2008

Purpose: The purpose of this study was to examine the relationship among cognitive function, depression, social support, and self-care in elderly with hypertension. Methods: The subjects were 132 elderly with hypertension living in Seoul, Korea. Data were collected through face-to-face interviews using the Korean version of Mini-Mental State Examination(MMSE-K), Short form geriatric depression scale, social support questionnaire 6, and hypertension self-care scale. Results: Thirty-four percent of the subjects had questionable dementia and forty-two percent of the subjects were depressed. Means for social support were 2.40 for network size and 4.07 for satisfaction. The mean score of hypertension self-care was 60.34, indicating that the subjects took care of themselves moderately well. Cognitive function was negatively related to depression. Social support network and satisfaction were negatively related to depression. Self-care was negatively related to social support network. Conclusion: Programs are needed for elderly with hypertension to improve their cognitive function, depression, and social support. Also further studies are needed to confirm the factors related to self-care in the elderly with hypertension.

• 생명과학회지
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• 제30권3호
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• pp.250-259
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• 2020

당뇨병은 치매 및 인지기능장애의 주요 위험인자로 알려져 있다. 당뇨병성 말초신경병증은 제2형 당뇨병에서 가장 흔히 발생되는 합병증으로 본 연구는 말초신경병과 인지기능항복 간의 관련성을 확인하기 위함이었다. 2005년부터 2016년 10월 31일까지 동아대학교의료원에 내원한 제2형 당뇨병 환자들을 대상으로 후향적으로 의무기록지를 확인하여 신경전도검사와 신경인지기능검사를 시행한 환자 총 19명을 대상으로 하였다. 총 19명 대상환자의 평균 나이는 71.6±5.0세, 당뇨병 유병기간은 8.4±9.1년, 당화혈색소는 8.1±1.8%였다. 당뇨병성 말초신경병증이 동반된 환자는 전체 19명 중 7명(36.8%)이었다. Korean version of the Mini Mental State Examination (K-MMSE) 검사 결과 총점 24점 미만으로 정의한 인지기능저하를 동반한 환자는 19명 중 8명(42.1%)였다. 당뇨병성 말초신경병증 동반 군과 동반하지 않은 군 간에 K-MMSE 점수와 인지기능저하 동반율은 차이가 없었다. 인지기능저하 동반군과 동반하지 않은 군 간에 DPN 동반 비율도 각각 37.5%와 36.4%로 유의한 차이가 없었다. 인지기능항목과 유의한 상관관계를 보인 변수는 교육 기간이었으며, 교육기간이 길수록 높은 인지기능과 관련이 있었다. 인지항목 중 digit span-forward 만이 신경전도속도(CV)와 유의한 음의 상관관계를 보였다. 결론적으로 제2형 당뇨병 환자에서 교육기간이 길수록 높은 인지기능과 관련이 있었으며, 당뇨병성말초신경병증과 인지기능장애 간에는 유의한 상관 관계가 관찰되지 않았다. 향후 더 큰 규모의 전향적 연구가 필요하다.

• 대한통합의학회지
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• 제8권4호
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• pp.49-58
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• 2020

Purpose : This study examined the effect of a home visit cognitive training program that uses a tablet-based digital recognition rehabilitation application, Brain Doctor, on local elderly people's cognitive function and depression. Methods : This study featured 20 elderly people living in Busan Metropolitan City, South Korea, who received a voucher for a home visit service to prevent dementia. The subjects were evenly divided into an intervention group provided with Brain Doctor and a control group provided with a conventional cognitive training program. Korean version of Mini Mental State Examination (MMSE-K) and Korean version of Montreal Cognitive Assessment (K-MoCA) were used to assess cognitive function in each group. Patient Health Questionnaire-9 (PHQ-9) was used to evaluate the depression levels. Results : The intervention group showed a significant change in cognitive function and depression after the intervention (p<.05). There was a statistically significant change in cognitive function and depression between the intervention and control groups (p<.05). Conclusion : This study confirmed that Brain Doctor had a positive effect on the cognitive function and depression of elderly people in the local community. It is expected to become a useful home visit program for dementia prevention in the future.

• 성인간호학회지
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• 제26권1호
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• pp.89-97
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• 2014

Purpose: During hospitalization, confusion occurs in 15~20% of older adults and persists in 5~10% of them. This study was designed to investigate effects of a five-day nursing intervention program designed to reduce confusion in hospitalized older adults. Subjects were inpatients over the age of 60 years old and were admitted in a surgical care unit. Methods: Data were collected from 111 patients. Subjects divided into one of two groups, 58 patients of the control group which received the usual nursing care; and 53 patients of the intervention group which received the usual nursing care plus nursing intervention program for reducing acute confusion. The Delirium Observation Screening Scale (DOS) and the Korean Mini-Mental Screening Examination (MMSE-K) were utilized. Results: 1) Acute delirium was significantly reduced in the intervention group compared to the control group ($x^2$=4.22, p=.034) as well as the duration of the delirious state was significantly shortened (F=56.62, p<.001). Cognitive function of the intervention group was improved (F=21.14, p<.001). Conclusion: The nursing intervention program reduced the incidence and duration of acute delirium of the elderly inpatients, as well as it helps them keep better cognitive function than the control group.

• 성인간호학회지
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• 제27권3호
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• pp.283-293
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• 2015

Purpose: Depression is a common sign of suffering among the patients with Parkinson's disease (PD). Frequent and severe neuropsychiatric symptoms lead to high levels of distress in patients and their caregivers, which results in the high levels of caregiver burden. The aim of this study was to determine the predictors of caregiver burden in caregivers of the patients with Parkinson's disease (PD). Methods: The study included 183 consecutive PD patients and their caregivers. Patients were assessed using the Hoehn and Yahr scale, Mini Mental State Examination (MMSE), Beck Depression Inventory (BDI), and Schwab and England Activities of Daily Living Scale. Caregivers' depressive symptoms were evaluated using the Caregiver Burden Inventor (CBI), BDI, and World Health Organization Quality of Life Scale. Results: All of the patients reported one or more neuropsychiatric symptoms. Patients' and caregivers' depressive symptoms, caregivers' age and education, time for caregiving, and quality of life were significantly associated with the increased caregiver burden. After controlling the level of education as a potential confounding variable, depression in both patients and caregivers, time for caregiving, and quality of life explained 45.6% of the variance in caregiver burden. Conclusion: Substantial attention needs to be given to the early identification of depression in PD patients and their caregivers to improve caregivers' quality of life and burden.