• 산경연구논집
• /
• 제3권1호
• /
• pp.25-29
• /
• 2012

The purpose of this study is to examine the development of the pharmaceutical distribution industry. The pharmaceutical industry is are expected to suffer a heavy blow when the Free Trade Agreement (FTA) is introduced, despite its best efforts. Therefore, adequate solutions must be found. Section II introduces the Korean pharmaceutical distribution system and its current situation; Section III explores the distribution system's strengths and weaknesses. Section IV, identifies the problem and possible solutions for the Korean pharmaceutical distribution system; Section V summarizes and concludes this paper and acknowledges its limitations. Finally, this paper has a clear limitation. The lack of objective information and scientific analysis due to the data being based on interviews with company representatives is its most significant shortcoming. However, it offers implications for new directions for future research.

• 유통과학연구
• /
• 제5권2호
• /
• pp.17-34
• /
• 2007

한국 제약산업은 제약회사의 수와 거래선의 수가 많고, 다품종 소량생산체제이며 동일성분의 경쟁품이 많은 실정이다. 이러한 실정 하에서 통합물류가 물류원가 절감 및 효율적인 배송에는 적절한 방안이라고 할 수 있으나 기업마다 다른 배송 조건 문제, 다품종 소량주문의 적기 배송 문제 등 회사 특유의 서비스 제공 등에 한계가 있어서 경쟁적 매출증가에 문제점이 있다 하겠다. 이와 같이 물류원가는 절감해야하고 영업효율성은 증대시켜야 하는 두 가지 문제를 두고 다음과 같은 대처방안을 제시하고자 한다. 첫째, 제약회사 간 품목 공동마케팅 실시. 둘째, 규모가 비슷한 3개 회사 이하 합동 배송실시. 셋째, 매출이 큰 제품은 도매상과 유통 일원화 협약. 넷째, 도매상이 제약 물류 서비스하도록 준비. 다섯째, 거래선의 협조 등이다. 결론적으로 한국제약산업에서 통합물류가 필요하지만 산업의 특성상 중소제약회사는 완전 통합물류는 매출이 감소할 것이라는 가정하에 그 시행이 어려울 것으로 판단되는 것이다.

• Journal of Pharmaceutical Investigation
• /
• 제12권4호
• /
• pp.153-174
• /
• 1982

• 고려인삼학회:학술대회논문집
• /
• 고려인삼학회 1993년도 학술대회지
• /
• pp.187-194
• /
• 1993

• 의료법학
• /
• 제24권3호
• /
• pp.3-26
• /
• 2023

의료인이 환자에게 직접 조제한다는 이유로 의약품공급자로부터 의약품을 취득하여 보관하고 있다가 스스로에게 투약한 경우의 약사법상 쟁점을 검토하였다. 의료인이 자가 투약 행위를 한 경우 의약품공급자나 의료인이 약사법에 따라 형사처벌될 수 있다. 그 가벌성은 약사법에서 규정한 의약품 유통 질서 훼손에 있다. 첫째, 의약품공급자가 의료인에게 의약품을 판매하는 것은 약사법 제47조 제1항 제1호 나목 위반죄의 구성요건에 해당한다. 다만, 약사법상 허용되는 직접 조제를 위해 판매한 경우 형법상 정당행위에 해당하여 위법성이 조각된다. 그러나 의약품공급자가 의료인의 자가 투약 목적을 알면서도 의약품을 판매한다면 위법성이 조각되지 않아서 형사처벌될 수 있다. 둘째, 의료인이 약사법상 직접 조제를 위하여 의약품을 취득한다고 명시적, 묵시적으로 의약품공급자를 기망하고 의약품을 취득하여 자가 투약한 경우, 기망에 의한 의약품 교부로 의료인에게 형법상 사기죄가 성립할 수 있다. 셋째, 의료인의 자가 투약 시 약사법상 조제 행위가 수반되므로 약사법 제23조 제1항 위반죄의 구성요건에 해당한다. 이때 위법성이 조각되지 않는다. 왜냐하면 의료인의 자가 투약 행위는 약사법에서 의료인에게 부여한 특별한 지위를 남용한 것으로 의약품 유통 질서를 해치고 의약분업의 취지를 훼손하는 것이어서 형법상 정당행위로 볼 수 없기 때문이다.

• Journal of Pharmaceutical Investigation
• /
• 제10권1호
• /
• pp.1-3
• /
• 1980

The model of an isolated organ system has been developed to simulate the kinetic behavior of drug levels in an acting organ or site. The model is developed from basic considerations of drug distribution with hemodynamical and pharmacokinetical meanings. Model: It is considered a situation in which non-metabolic drug substance is injected into the arterial inflow of an isolated organ at constant rate. The volume of distribution and the concentration of drug in the venous outflow can be mathematically expressed as a function of time.

• 산경연구논집
• /
• 제12권5호
• /
• pp.27-36
• /
• 2021

Purpose: This study empirically investigates the effect of collaborative communication and information sharing on the supply chain performance of South Korean pharmaceutical companies. Specifically, it understands the importance collaborative communication and suggests a method for investigating communication in academic research on the pharmaceutical industry. Investigating this sector is crucial because the importance of the pharmaceutical industry is increasing globally against the background of the Covid-19 pandemic. Research design, data, and methodology: A questionnaire was administered to employees of South Korean pharmaceutical companies and 244 valid responses were used for the statistical analysis. Additionally, structural equation modeling was used to measure the relationships between the observed and latent variables. Results: Collaborative communication has a positive effect on information sharing. However, information sharing, unlike collaborative communication, does not exhibit a significant positive relationship with supply chain performance. These results indicate that it is important to communicate effectively in the supply chain rather than strive for the right type of information sharing. Conclusions: Consumers and retailers within the supply chain should continue to strive for candid communication. This study is meaningful, as it empirically tests the relationships between collaborative communication, information sharing, and supply chain performance in the South Korean pharmaceutical industry.

• 한국임상약학회지
• /
• 제20권2호
• /
• pp.128-137
• /
• 2010

This review summarizes gender differences in pharmacokinetics, pharmacodynamics, and adverse drug reactions. Gender differences in pharmacokinetics are categorized by four major factors: absorption/bioavailability, distribution, metabolism, and elimination. There are sex-based differences in gastric emptying time, gastric alcohol dehydrogenase activity, apparent volume of distribution, ${\alpha}1$-acid glycoprotein level, phase I (CYP) and phase II metabolizing enzymes, glomerular filtration rate, and drug transporters. This review also reports gender differences in pharmacokinetics and pharmacodynamics of cardiovascular agents, central nervous system acting agents and antiviral agents. In addition, it has been reported that females experience more adverse reactions such as coughing, tachycardia, nausea, vomiting, rash, hypersensitivity, hepatotoxicity, and metabolic disorder after taking cardiovascular, central nervous system acting and antiviral agents. Therefore, in order to provide optimal drug dosage regimens both in male and female, gender differences in pharmacokinetics, pharmacodynamics, and adverse drug reactions must be considered.

• Journal of Pharmaceutical Investigation
• /
• 제17권1호
• /
• pp.41-46
• /
• 1987

Oil in water microemulsion containing soybean oil and egg phosphatide was prepared by vacuum high shear mixing and high pressure homogenizing. The laser particle sizer, Coulter counter and photomicroscope were used to determine the particle size distribution at each cycle of homogenizing. Particularly, the laser particle sizer(dynamic light scattering method) was applied to the study of particle size distribution behavior below $1\;{\mu}m$. It was found that the particle size distribution below $1\;{\mu}m$ was shifted to lower size range as the number of passing cycle was increased. Beyond the 7th cycle, however, the particle size distribution was not varied.

• 한국독성학회:학술대회논문집
• /
• 한국독성학회 2003년도 추계학술대회
• /
• pp.120-120
• /
• 2003

Synthesis and distribution of extracellular matrix (ECM) components are dynamically altered in response to the pathophysiological processes including infection, inflammation and apoptosis. In particular, the levels of hyaluronan (HA) change with concomitant increases in the levels of collagen (e.g. type I collagen) and fibronectin in chronic liver diseases.(omitted)