• 대한한방내과학회지
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• 제43권6호
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• pp.1105-1121
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• 2022

Objectives: The purpose of this study is to explore the effectiveness and safety of frequently used clinical herbal medicines (Yijung-tang [Lizhong-tang, LJT], Pyeongwi-san [Pingwei-san, PWS], and Shihosogan-tang [Chaihu Shugan-tang, SST]) in patients with functional dyspepsia (FD) when administered according to herbal medicine and Korean medicine pattern identification. The results of this study will be used to standardize the diagnostic instrument used in Korean medicine and to investigate biomarkers of Korean medicine pattern identification. Methods: This study will be a randomized, assessor-blind, 3-arm, parallel, open-label, multi-center clinical trial. A total of 300 FD participants will be recruited from 3 Korean medical hospitals and assigned to the LJT (n=100), PWS (n=100), and SST (n=100) groups according to FD pattern identification. The patients will take the medication for 8 weeks, 3 times a day, before or between meals. The primary outcome will be total dyspepsia symptom (TDS) and the secondary outcomes will be adequate relief (AR) for dyspepsia, overall treatment effect (OTE), visual analogue scale (VAS), functional dyspepsia-related quality of life (FD-QoL), gastrointestinal symptom score (GIS), and pattern identification questionnaires. For the exploratory outcomes, we will analyze blood and fecal metabolome profiles, microbiota from fecal and saliva samples, single nucleotide polymorphism (SNP), and results of Korean medicine diagnosis device measurements (heart rate variability, and tongue, pulse, and abdominal diagnosis). Conclusions: The results of this study will prove objectivity for Korean medicine pattern identifications, and the effectiveness and safety of herbal medicines for the population with FD.

• 대한한방부인과학회지
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• 제23권3호
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• pp.123-138
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• 2010

Purpose: The purpose of this study is to identify the real condition of urinary incontinence(UI), interstitial cystitis(IC), atrophic viginitis(AV) for elderly women and analyze the cognition of traditional korean medicine(TKM) for them. Methods: We utilized questionnaire from May to June, 2010. Questionnaires were taken from 125 women using senior welfare center and nursing home, aged over 65 up to 92. The data were analyzed by $X^2$-test using SPSS/PC ver 18.0 program. Results: The prevalences of UI, IC and AV symptoms were 50.4%, 40.8%, 56%, respectively. The average I-QoL score for UI was $82.62{\pm}21.16$, and the average ICSI score for IC was $8.16{\pm}2.50$. After adjustment for each of the variables considered in this study, alcohol was associated with UI and age, BMI(body mass index) were associated with IC. Most of respondents have no experience(94.4%) or don't know (79.2%) about TKM for UI, IC and AV. 44 women(37.3%) indicated that they weren't willing to use TKM for UI, IC and AV. Reasons for not taking TKM were because of 'no knowledge of TKM(34.1%)' and 'more accustomed to western treatment(34.1%)'. Conclusion: Although the prevalence of UI, IC, AV for elderly women was high, the actual percentage of treatment for these diseases was low, furthermore, patients were not aware of TKM and had very few experiences of TKM for these diseases. The development and increased promotion about TKM program for elderly women's urogenital diseases is needed.

• 동의생리병리학회지
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• 제27권2호
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• pp.253-260
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• 2013

This study was focused on the relationships between menstrual history and psychological variables in middle school girls. The study included 165 students. Self image, optimism and self-efficacy are measured structured questionnaires each. Statistical analysis was performed using t-test, ANOVA and Scheffe's test. The proportion of the students with bleeding period less than 7 days was higher in the group with high self image(p=.002). The self image was higher in the group who take analgesics occasionally than the group who take daily(p=.009) and in the group with irregular menstruation(p=.024). Emotional tone was higher in the group with irregular menstruation(p=.008), and psychopathology was higher in the group who take analgesics occasionally(p=.008). Family relationship was higher in the group with bleeding period less than 7 days(p=.004), in the group who take analgesics occasionally(p=.007) and in the group with irregular menstruation(p=.015). Mastery and coping was higher in the group with bleeding period less than 7 days(p=.026). Adaptation was higher in the group with irregular menstruation(p=.034). Also optimism was higher in the group with bleeding period less than 7 days(p=.005), in the group who experienced menorrhalgia a few years after menarche(p=.014) and the group with irregular menstruation(p=.027). Self-efficacy was higher in the group of polymenorrhea(p=.029). Because menstruation is related with psychiatric factors, it is necessary to ask menstruation history and psychiatric status. This study can be used in the development of the questionnaire for the oriental medical examination.

• 성인간호학회지
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• 제26권2호
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• pp.191-202
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• 2014

Purpose: This study was aimed to survey the actual caregiving conditions of family caregivers who are caring patients with rare and incurable diseases using home ventilators at home, and to clarify any factors affecting their burdens and quality of life. Methods: A questionnaire survey was performed by the 159 subjects, and the questionnaires contained the actual conditions of caregiving activities, and caregiver's burdens and quality of life. The collected data was analyzed by ANOVA, Pearson's correlation, and stepwise linear regressions. Results: The mean of burden scores was 3.55 out of 5, and influencing variables included the relationships with patient (spouse), respite (moderate), health status, and diagnosis (non ALS), with the explanatory power of 30.0%. The mean of the quality of life was 2.58 point, and the influencing variables included burdens, health status, and respite (enough), with the explanatory power of 39.0%. Conclusion: In order to improve the quality of life among family caregivers caring for patients with using a home ventilator, it is required to develop strategies for reducing caregiving burdens as well as to introduce family respite welfare systems to family caregivers.

• 한국식품영양과학회지
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• 제44권1호
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• pp.49-56
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• 2015

본 연구는 지역사회에서 거주하고 있는 재가노인을 대상으로 삼킴장애 위험군을 선별하여 위험 실태를 파악하고 관련인자를 조사하고자 하였다. 서울, 경기 및 충북 지역에 거주하는 65세 이상 재가노인 419명을 대상으로 2012년 9월에서 12월까지 일대일 면접방법으로 설문자료를 수집하였다. 주요 연구 결과는 다음과 같다. 첫째, 전체 응답자 가운데 과반수(53.50%)가 삼킴장애 위험군으로 판정되었고 삼킴장애 위험점수는 평균 13.17점으로 국내외 선행연구보다 높은 수준이었다. 둘째, 노인의 삼킴장애 위험도는 65~74세군보다 75세 이상군에서 높았고, 의치를 하는 경우와 일상생활에서 독립성이 떨어지는 경우에 유의하게 높았다. 셋째, 삼킴장애 위험군과 비위험군에서 노인의 식품섭취 문제와 그에 따른 향후 섭취 문제 위험 여부를 조사한 결과 삼킴장애 위험군은 비위험군보다 식욕부진, 식사량 감소, 잦은 결식, 입맛이 나쁘다고 응답한 경우가 많았으며 이에 따라 향후 섭취 문제 위험도가 유의하게 높은 것으로 나타났다. 결론적으로 국내 재가노인의 삼킴장애 실태는 간과하기 어려운 수준이며 향후 지역사회의 다양한 환경에 있는 노인들을 대상으로 연구가 확대되어야 할 것이다.

• 사상체질의학회지
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• 제10권1호
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• pp.81-99
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• 1998

1. 연구배경 : 사상체질의학에서 체질의 진단은 매우 중요하다. 전체적이고 직관적으로 제시된 동의수세보원의 체질진단 방법을 객관화 할 필요가 있다. 이를 위하여 신체 각 부위의 형태학적인 연구를 통하여 사상체질 유형을 가려내려는 시도가 이루어지고 있으며, 그 중의 하나는 생체 계측 방법을 이용하는 것이다. 본 연구에서는 체질인류학 연구 방법 중의 하나인 지문과 손바닥문의 분석 방법이 사상체질 유형을 가려내는 데 얼마나 도움 되는지 밝히고자 하였다. 2. 방법 : 특별한 질병이 없는 한국사람 347명(남자 241명, 여자 106명)에게 설문지 I 형과 QSCCII를 실시하여 두 가지 방법에서 같은 체질로 진단된 208명(남자 142명, 여자 66명)의 지문과 손바닥문을 채취하여 분석하였다. 삼교차점의 수에 따라 지문의 유형을 분석하였고, 지문의 중심에서 삼교차점까지 직선을 그어서 만나는 피부능선의 수를 세었다. 각 손가락의 몸쪽에 있는 손바닥문의 삼교차점에서 일어나는 피부능선을 추적하여 손바닥문의 유형을 분석하였고, 손바닥문의 삼교차점 사이에 직선을 그어서 만나는 피부능선의 수를 세었다. 그리고 손바닥문의 삼교차점이 이루는 atd각도를 측정한 후 사상체질 유형과 관련성을 살펴보았다. 3. 연구결과 및 결론 : 208명의 사상체질 유형은 태음인 76명(36.5%), 소음인 81명(39.0%), 소양인 51명(24.5%)이었고, 지문과 손바닥문의 분석 결과는 다음과 같았다. 지문의 유형은 태음인을 가려내는 데 도움이 되었고, 손바닥문의 유형은 태음인, 소양인, 소음인을 모두 가려내는 데 도움 되었다. 특히 손바닥문 유형은 소양인과 소음인을 가려내는 데 큰 도움이 되었다. 또한 지문과 손바닥문의 피부능선수는 소양인을 가려내는 데 도움 되었다 . 지문과 손바닥문은 사상체질 유형마다 특징적인 경향이 있으므로 사상체질 유형을 가려내는 데 도움이 도움 될 것으로 기대되며, 향후 본 연구자는 더 많은 사람을 대상으로 지문과 손바닥문 그리고 손금을 함께 관찰하여 보고할 예정이다.

• 대한의료기공학회지
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• 제8권1호
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• pp.96-114
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• 2005

This study was carried out to provide essential data for the future health promotion projects to be aimed at improving quality of life for the elderly people in the increasingly aging society of Korea by investigating factors related to the yangseng of old people in urban areas. The results of this study are to be used as basis for efficient approach toward health promotion projects for the elderly in urban communities. For the purpose, a survey by questionnaires was conducted to urbanites from May th June 2004. The collected replies were analyzed from the viewpoints of Oriental Medicine for yangseng. 1. The average points of health care were 3.24. In details by sub-areas, 3.78 was rated for morality yangseng, 3.29 for mind, 3.30 for diet, 3.79 for activity and rest, 2.32 for exercise, 3.72 for sleeping, 2.95 for season and 1.81 for sexual life, which showed that the area of activity and rest yangseng was scored highest while the area of sexual life yangseng was rated lowest. 2. As for the extent of health care depending on the characters of subjects, higher scores were rated by men than women, younger ones than aged and spoused ones than singles. Married couples living without other family members were found to yangseng most, while more yangseng was taken by the educated, job holders and those who utilize leisure and have religion in order. 3. Men exercised more yangseng than women in the diet, exercise and sleeping. By age, the group aged 65 to 69, the more yangseng in the exercise and sexual life. The group with spouse featured higher concern for yangseng in all categories except for season. Married couples who are living with no other family members recorded the highest point in all areas except for exercise. 4. The more one is educated, the more he/she is tended to take yangseng in the sub-areas of exercise and sexual life. The group with occupation is also inclined to take more yangseng in the same sub-areas as those of the highly educated. When they pay living cost together with offspring, they appeared to be the most yangseng in season and sexual life. People who enjoy leisure showed higher yangseng in all areas except for season. Religion had a significant influence in all areas except for activity and rest yangseng. 5. Those who reply that they are confident with health and have no disease proved to have higher yangseng. Depending on whether one has disease or not, higher yangseng was confirmed in such sub-categories as mind and sleeping. Those who replied they are confident with health had higher yangseng in all areas except for season. As seen above, yangseng of the old people in the urban area is found to have different extent depending on the individual and socioeconomic characters, factors which should be seriously considered in the local health promotion projects and projects for the health of the elderly. It seems therefore necessary to launch health promotion programs and to analyze their effects to promote health care particularly in the areas of sexual life, exercise and season yangseng that featured lowest grade of yangseng in each sub-area.

• 대한물리치료과학회지
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• 제9권3호
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• pp.19-29
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• 2002

This study questionnaires 166 inpatients and outpatients with stroke in 8 hospitals, including Wonkwang University Gwangju Korean Hospital from July 2 to 31, 2001 in order to find out the influence of general nature, smoking, drinking, obesity, and perception of saltness of patients with stork on the outbreak of stroke and to examine important factors by dividing into hemorrhagic and ischemic stroke. Finally, collected data is analyzed statistically, using SPSS 7.5 statistics package. This study reaches a conclusion as follows. 1. For general nature, 86(51.8%) patients have hemorrhagic stroke and 80(48.2%), ischemic stroke in the rate of 1.59:1(male:female), suggesting that male's outbreak is more than female's. Outbreak age is ranged from 20 years to 90 years in order of 60's, 50's, and 40's. 50's-60's accounts for more than half percentage. 2. For smoking, 73(71.6%) of male patients has smoking experience and their 562% has ischemic stroke. Their cross-analysis for hemorrhagic and ischemic stroke shows significant difference with $x^2=3.90$(p<0.05). 48.6% of patients with smoking experience is ranged from 1 to 10 a day in smoking quantity. 3. For drinking, 90(88.2%) of male patients has drinking experience and their 53.3% has hemorrhagicstroke. Their cross-analysis for hemorrhagic and ischemic stroke shows no significant difference with x2=3.40(p<0.1). 59.3% of patients with drinking experience is classified as a overdrinking group. 4. For obesity, low weight is 8(4.8%): normal, 111(66.9%): excessive, 40(24.1%), and obesity, 7(4.2%). In patients with hemorrhagic stroke, excessive weight and obesity are somewhat high(33.7%). The cross-analysis for male's hemorrhagic and ischemic stork by dividing BMI into more and less than 25 shows no significant difference with x=3.52(p<0.1). 5. For perception of saltness, 21(12.7%) patients eat flat: 76(45.8%) normally, and 69(41.5%), saltily. Many patients with ischemic stroke are classified as a group who eat saltily. The cross-analysis for male's hemorrhagic and ischemic stroke shows signifiant difference with x2=10.99(p<0.05). As this study has small sample and selects inpatient and outpatient in certain local hospital, it is difficult to generalize. But the cross-analysis of male's hemorrhagic and ischemic stroke shows signifiant difference in smoking and perception of saltness. Drinking and obesity are more important factors in hemorrhagic stroke and smoking and perception of saltness in ischemic stroke.

• 한국식품영양과학회지
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• 제43권9호
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• pp.1431-1438
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• 2014

본 연구는 국내 노인의 삶의 질과 영양개선 및 건강을 증진시킬 수 있는 기초자료를 얻고자 실시된 단면연구로서 재가 노인의 식욕부진 유병 상태를 조사하고, 식욕부진과 관련된 사회 인구학적 특성, 병리적 특성과 심리 특성 및 일상생활 수행능력 등을 조사하였다. 자료 수집은 서울, 경기, 충북 지역의 65세 이상 재가 노인 419명을 대상으로 2012년 9월에서 12월까지 구조화된 설문지를 이용하여 일대일 면접방법으로 수행하였다. 연구 결과 국내 노인의 식욕부진 유병률은 전체 응답자 가운데 35.1%였고, 특히 남성노인의 식욕부진 유병률이 여성노인보다 유의하게 높았다. 남성노인의 식욕부진은 중추신경계 질환을 진단받은 경우가 가장 많았고 여성노인의 경우 식욕부진은 내분비 질환이 있는 경우가 가장 많았다. 또한 우울증 증상이 있거나 일상생활에서 의존도가 높은 경우 식욕부진이 현저한 것으로 관찰되었다. 이상의 결과로부터 국내 재가 노인들의 식욕부진이 심각한 수준임을 알 수 있었고, 노인의 식욕부진은 생리적 특성과 병리적 특성은 물론 우울과 같은 심리적 특성과도 깊은 상관성이 있음을 알 수 있었다. 향후 노인의 식욕부진 개선이나 예방을 위하여 구체적인 영양중재와 영양치료가 필요하며, 노인인구 증가에 따라 노인의 식욕증진을 고려한 노인식품 개발이 시급히 필요할 것으로 생각된다. 본 연구 결과는 다음과 같은 제한점을 갖는다. 본 조사는 단면연구이므로 연구 결과에서 나타난 식욕 수준에 관련된 인자들이 노인의 식욕부진 원인으로 작용했는지는 알 수 없다. 따라서 추후 보다 대표성을 갖는 한국 노인을 대상으로 노인의 식욕부진 유병률의 조사는 물론 식욕부진과 관련된 원인 규명을 위하여 횡단연구가 필요하다. 또한 노인을 일대일 대면하여 자가보고 하는 방법으로 자료를 수집하였으므로 문항에 따라서는 노인에 따라 사실보다 과장하거나 축소하는 등 응답 수준이 주관적일 수도 있다. 그럼에도 불구하고 본 연구에서 나타난 식욕부진과 관련된 인자들은 선행 연구와 유사하며 따라서 자가보고에 의한 사회적 기대 효과는 다소 적었다고 판단된다. 향후 재가노인의 범위를 성별, 연령별, 지역별, 거주형태별 등으로 일치시키고 확대하여 노인의 식욕부진 실태와 관련 인자 연구의 확대를 제안한다.

• 한방안이비인후피부과학회지
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• 제23권1호
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• pp.199-214
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• 2010

Objective : Atopic dermatitis (AD) may profoundly affect patient's quality of life (QOL), and also cause economic impact. The aim of our study was to evaluate the quality of life and the economic impact of adult atopic dermatitis patient in Seoul. We also evaluate the relationship of QOL and economic impact with severity of AD. Methods : 30 adult atopic dermatitis patient were included and evaluated by using the SCORAD Index and EASI. Patients were asked to fill in the questionnaires about their quality of life and financial costs during the past year by AD. Data about sleep disturbance and pruritus were also obtained. Pearson's correlation were used for statistical analysis. Results : 1. Among 30 patients, women were 19(63.3%), men were 11(36.7%). The mean age of the patients were 27.3 years old, patients between the ages of 17 and 30 years were 23, over 30 were seven. 2. The mean score of Objective SCORAD was $32.89{\pm}7.30$, Subjective SCORAD was $8.13{\pm}3.53$ and EASI was $9.15{\pm}6.90$이었다. 3. The mean score of Skindex-29 was $28.26{\pm}7.58$, DLQI was $10.17{\pm}5.55$. 4. By analyzing the questionnaire, a monthly average cost of 583,200 won for each patient was determined. Direct cost was 236,800 won and indirect cost was 346,300 won. 5. By analyzing the correlation between the severity of AD and QOL, Objective SCORAD and EASI were positively correlated with QOL(Skindex-29, DLQI) but not significant, meanwhile subjective SCORAD were significantly and positively correlated with QOL(Skindex-29, DLQI). 6. By analyzing the correlation between the severity of AD and economic impact, Objective SCORAD were significantly and positively correlated with direct cost and indirect cost. Also, EASI were significantly and positively correlated with direct cost and oriental medical hospital visits. Conclusions : The above results show that the QOL of the patients with atopic dermatitis is significantly related to their disease severity. Atopic dermatitis patients pay 583,200 won a month, and the economic impact of the patients is significantly related to their disease severity.