• 농촌계획
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• 제12권3호
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• pp.39-42
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• 2006

The purpose of this study is to develop rural population model adapting cohort survival method with sift-share effects. Administrative district in this study is below Myun: about 2,000 population. Population data of rural area in 1990, 1995, and 2000 by age cohort were selected for applying developed model. Damping coefficient from population data was calculated as 7% and results applying this coefficient in rural population data below the error from 12% to 1.06%. In detail, most of cohorts fitted with developed model except from 15 to 29 age groups. Application result of small population area; DaesulMyun revealed that main factor of population change is not natural change but migration.

• 대한지리학회지
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• 제46권2호
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• pp.212-232
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• 2011

이 연구의 목적은 이지역 코호트 요인법에 의한 인구 추계 방법론을 정립하고, 그것을 부산광역시의 장래 인구 추계에 적용하는 것이다. 우선 시도와 같은 지역 인구의 추계에 있어 우리나라의 공식적인 방법인 순이동 코호트-요인법이 갖는 한계를 예증하였다. 대안으로 지역간 코호트-요인법 중 전체 지역을 두 지역으로 구분한 후 지역 간의 전입과 전출을 분리하여 추계하는 이지역 코호트-요인법을 정립하였다. 이를 바탕으로 부산광역시의 2005~2030년에 대한 인구 추계를 3가지 시나리오 하에서 실행하였다. 순이동 방식을 취한 인구 추계와 이지역 방식을 취한 인구 추계 간에는 상당한 차이가 나타났는데, 전출 초과 지역인 부산의 경우 순이동 방식에서 더 빠른 인구 감소가 나타났다. 이지역 방식에 의한 부산 및 전국추계의 인구 변화 추세를 검토한 결과 추계가 상당히 합리적으로 이루어짐을 확인할 수 있었다. 결론적으로 본 연구에서 제시된 이지역 코호트-요인법은 순이동 코호트-요인법에 비해 논리적으로 더 정연하면서도 실제 추계에 있어서도 높은 유용성을 보여 주었다.

• Korean Journal of Radiology
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• 제24권4호
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• pp.274-283
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• 2023

Objective: To compare the outcomes of digital breast tomosynthesis (DBT) screening combined with ultrasound (US) with those of digital mammography (DM) combined with US in women with dense breasts. Materials and Methods: A retrospective database search identified consecutive asymptomatic women with dense breasts who underwent breast cancer screening with DBT or DM and whole-breast US simultaneously between June 2016 and July 2019. Women who underwent DBT + US (DBT cohort) and DM + US (DM cohort) were matched using 1:2 ratio according to mammographic density, age, menopausal status, hormone replacement therapy, and a family history of breast cancer. The cancer detection rate (CDR) per 1000 screening examinations, abnormal interpretation rate (AIR), sensitivity, and specificity were compared. Results: A total of 863 women in the DBT cohort were matched with 1726 women in the DM cohort (median age, 53 years; interquartile range, 40-78 years) and 26 breast cancers (9 in the DBT cohort and 17 in the DM cohort) were identified. The DBT and DM cohorts showed comparable CDR (10.4 [9 of 863; 95% confidence interval {CI}: 4.8-19.7] vs. 9.8 [17 of 1726; 95% CI: 5.7-15.7] per 1000 examinations, respectively; P = 0.889). DBT cohort showed a higher AIR than the DM cohort (31.6% [273 of 863; 95% CI: 28.5%-34.9%] vs. 22.4% [387 of 1726; 95% CI: 20.5%-24.5%]; P < 0.001). The sensitivity for both cohorts was 100%. In women with negative findings on DBT or DM, supplemental US yielded similar CDRs in both DBT and DM cohorts (4.0 vs. 3.3 per 1000 examinations, respectively; P = 0.803) and higher AIR in the DBT cohort (24.8% [188 of 758; 95% CI: 21.8%-28.0%] vs. 16.9% [257 of 1516; 95% CI: 15.1%-18.9%; P < 0.001). Conclusion: DBT screening combined with US showed comparable CDR but lower specificity than DM screening combined with US in women with dense breasts.

• 대한예방의학회:학술대회논문집
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• 대한예방의학회 2003년도 제11회 춘계 심포지움 연제집
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• pp.30-37
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• 2003

o Cohort study became the major approach to study of chronic diseases such as CVD and cancer o Cohort can be population-based or volunteer-based o Types of be population-be categorized by source population and selection mechanism o More and more cohort studies involve biological specimens, such as blood, urine, toenail, cheek cells, etc. o Multi-center and multi-national collaboration is an effective way to increase sample size. o Current statistical method typically use time-to-event analysis by Cox proportional hazard model.

• Annals of Geriatric Medicine and Research
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• 제20권3호
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• pp.114-117
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• 2016

A research project, the "Construction of Frailty Cohort for Elderly and Intervention Study," funded by the Ministry of Health and Welfare, has been ongoing since December 2015. The Korean Frailty and Aging Cohort Study (KFACS) aims to identify risk factors for adverse outcomes associated with frailty in community-dwelling older adults, as well as means of prevention. KFACS is a multicenter, longitudinal study, with the baseline survey being conducted in 2016-2017. The sample (n=3,000) consists of those aged 70-84 years, stratified by age and gender, recruited from urban and rural regions nationwide. An in-person interview and health examination are performed every 2 years. This project is also conducting many intervention studies. Project interventions focus on nutrition and exercise. The nutritional intervention study compares the effects of 1.2 g/kg versus 1.5 g/kg daily protein intake on sarcopenia and frailty in older Koreans. The exercise trial examines the effectiveness of an information and communication technology-based program in preventing or reducing frailty.

• Journal of Preventive Medicine and Public Health
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• 제27권1호
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• pp.117-134
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• 1994

대구직할시 남구 1 개동 주민을 대상으로 도시 지역의료보험 실시 전후(이하 실시 전후)의 의료 이용양상을 파악하기 위하여 실시 6개월 전인 1989년 1월에 1차조사를 하였고, 실시 1년 6개월 후인 1991년 1월에 2차조사를 하였다. 1차조사의 대상자는 1,230가구 4,939명이 었으나, 2차추적조사가 가능했던 인구는 519가구 2,277명 (추적률:46.1%)이었다. 2차조사까지 추적이 가능했던 2,277명 중 1차 조사시 보험에 가입되지 않았던 240가구 1,033명을 코호트 I군(이하 I군)으로 하였고, 1차조사시 보험에 가입되었던 279가구 1,244명을 코흐트 II군(이하 II군)으로 구분하여 조사자료를 분석하였다. 인구 1,000명당 급성이환으로 인한 의사방문율의 변화는 실시 후에 I군에서 16.5 증가한 반면, II에서는 2.4만 증가하였으며, 만성이환에서도 I군이 13.5 증가하였으나 II군은 7.2만 증가하였다. 이환 및 활동제한 의료필요 충족률도 I군에서 실시 후 뚜렷히 증가하였다. 월가구소득별 급성이환에 의한 의료필요충족률은 I군에서 40만원미만군이 1.6으로 $40{\sim}99$만원군의 4.0과 100만원이상군의 49.3에 비해 월등히 낮았다. 이러한 소견은 나머지 조사대상군과 만성이환에서도 동일하였다. 급성과 만성이환자의 병원이용 이유는 유용성, 의원의 경우는 지리적 접근성이 실시전후모두에서 가장 많았고 약국이용 이유 중 실시 전에는 접근성과 의료비지불성이 중요하였으나, 실시 후에는 의료비지불성의 중요성은 상대적으로 감소하였다. 최근 15일간 의사방문여부를 종속변수로한 multiple logistic regression analysis에서 급성이환(+), 만성이환(+) 그리고 월가구소득(+)이 실시전후 모두에서 유의한 변수였다. 실시 후 부과된 보험료에 대한 불만족률이 두군 모두 지역의료보험 가입자에서 각각 81.0%와 74.1%로 타 의료보험가입자에 비해 월등히 높았다. 실시 후 병원과 의원의 의료비와 서어비스에 불만족스럽다고 응답한 사람이 I군에 비해 II군에서 더 많았다. 이상의 소견으로 의료보험이 실시됨으로 미충족의료수요를 감소시키는 효과를 가져왔으나 실시 후에도 저소득층의 의료이용률이 고소득층에 비해 여전히 낮아 의료보험실시로 경제적 장애가 감소하였음에도 불구하고 본인부담금 등으로 인한 경제적 장애와 의료기관을 방문하는데 소요되는 시간, 대기시간 등 의료이용을 저해하는 요인이 남아있어 의료이용의 형평이 사회계층들간에 완전히 이루어지지는 않았다. 특히 만성이환의 경우, 불균형이 심하였다. 또한, 부과된보험료에 대한 불만족도가 높아 현행 보험료선정기준의 재평가 및 공정성을 향상시킬 필요성이 제기되었다.

• Journal of Preventive Medicine and Public Health
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• 제48권6호
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• pp.280-286
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• 2015

Objectives: Approximately 10% to 15% of lung cancer cases occur in never-smokers. Hormonal factors have been suggested to lead to an elevated risk of lung cancer in women. This systematic review (SR) aimed to investigate the association between hormonal replacement therapy (HRT) and the risk of lung cancer in women using cohort studies. Methods: We first obtained previous SR articles on this topic. Based on these studies we made a list of refereed, cited, and related articles using the PubMed and Scopus databases. All cohort studies that evaluated the relative risk of HRT exposure on lung cancer occurrence in women were selected. Estimate of summary effect size (sES) with 95% confidence intervals (CIs) were calculated. Results: A total of 14 cohort studies were finally selected. A random effect model was applied due to heterogeneity (I-squared, 64.3%). The sES of the 14 articles evaluating the impact of HRT exposure on lung cancer occurrence in women indicated no statistically significant increase in lung cancer risk (sES, 0.99; 95% CI, 0.90 to 1.09). Conclusions: These results showed that HRT history had no effect on the risk of lung cancer in women, even though the sES of case-control studies described in previous SR articles indicated that HRT had a protective effect against lung cancer. It is necessary to conduct a pooled analysis of cohort studies.

• 농촌의학ㆍ지역보건
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• 제31권2호
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• pp.119-144
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• 2006

The Korea rural health study, a large prospective cohort study, the objectives of this study are exploration for potential causes of agricultural injuries and diseases among farmers. Current medical research suggests that they may have higher rates of some traumatic injuries, pesticide poisoning, infectious diseases, musculoskeletal diseases, asthma and other respiratory diseases. This study is designed to identify occupational, lifestyle, and environmental factors of workplace that may affect the rate of diseases in farming population. Round 1, initial cohort recruitment, will begin in 2006 and conclude in 2009. Round 2, follow-up will begin in 2010 and conclude in 2014. Approximately 54,000 persons will be selected to study population. Nested case-control studies and case-crossover studies will be conducted for getting to the bottom of agriculture-related diseases. Recruitment and follow-up are conducted in collaboration with multi-centers. As data on the exposures and health outcomes of this study population are collected and analyzed in 2014. This study will be evaluated by public health experts for effort, achievement, adequacy of performance, efficacy, process of study and so on. The author expects that this cohort study may reduce agricultural injuries and diseases and will provide information that agricultural workers can use in making decisions about their health. Also, this study will be significant basis for strengthening the competitiveness of agriculture in Korea.

• 의학교육논단
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• 제25권2호
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• pp.126-131
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• 2023

The aim of this study was to systematically collect data for evaluating short- and long-term outcomes using Kirkpatrick's four-level evaluation model, Chonnam National Medical School has established plans for developing and managing a database of student and graduate cohorts. The Education Evaluation Committee, with assistance from the Medical Education Office, manages the development and maintenance of cohort data. Data collection began in the 2022 academic year with first- through fourth-year medical students and graduates of the year 2022. The collected data include sociodemographic characteristics, admission information, psychological test results, academic performance data, extracurricular activity data, scholarship records, national medical licensing exam results, and post-graduation career paths. The Education Evaluation Committee and the Medical Education Office analyze the annually updated student and graduate cohort data and report the results to the dean and relevant committees. These results are used for admissions processes, curriculum improvement, and the development of educational programs. Applicants interested in using the student and graduate cohort data to evaluate the curriculum or conduct academic research must undergo review by the Educational Evaluation Committee before being granted access to the data. It is expected that the collected data from student and graduate cohorts will provide a sound and scientific basis for evaluating short- and long-term achievements based on student, school, and other characteristics, thereby supporting medical education policies, innovation, and implementation.

• 음성과학
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• 제9권2호
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• pp.135-146
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• 2002

Generally a speaker verification system improves its system recognition ratio by regularizing log likelihood ratio, using a speaker model and its background speaker model that are required to be verified. The speaker-based cohort method is one of the methods that are widely used for selecting background speaker model. Recently, Gaussian-based cohort model has been suggested as a virtually synthesized cohort model, and unlike a speaker-based model, this is the method that chooses only the probability distributions close to basic speaker's probability distribution among the several neighboring speakers' probability distributions and thereby synthesizes a new virtual speaker model. It shows more excellent results than the existing speaker-based method. This study compared the existing speaker-based background speaker models and virtual speaker models and then constructed new virtual background speaker model groups which combined them in a certain ratio. For this, this study constructed a speaker verification system that uses GMM (Gaussin Mixture Model), and found that the suggested method of selecting virtual background speaker model shows more improved performance.