• 제목/요약/키워드: Korean clinic

검색결과 7,444건 처리시간 0.035초

Genuine traditional Korean medicine, BaekJeol-Tang for the treatment of rheumatoid arthritis

  • Han, Na-Ra;Sim, Woo-Moon;Sul, Moo-Chang;Kim, Min-Cheol;Lee, Chang-Hee;Kim, Dong-Won;Lee, Se-Hun;Lee, Ho-Cheol;Ryu, Jong-Min;Nam, Bong-Soo;Kim, Jong-Ok;Moon, Seong-Oh;Jang, Hyeon-Lok;Kim, Young-Seok;Lee, Ihn;Yang, Jin-Young;Hwang, Kyu-Sun;Chun, Chang-Sun;Jeong, Hyeon-Seok
    • CELLMED
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    • 제3권2호
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    • pp.18.1-18.7
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    • 2013

  • Inflammation in rheumatoid arthritis is characterized by immune cell infiltration and cytokine secretion. In particular, mast cells and their cytokines play an important role in the pathogenesis of rheumatoid arthritis. Korean medicine, BaekJeol-Tang (BT) was designed by traditional Korean medicine theory. We already reported therapeutic effect of BT in rheumatoid arthritis. Here, we report the specific underlying mechanism of BT in activated human mast cells, HMC-1 cells. In addition, we report for the first time that BT significantly inhibited the production and mRNA expression of proinflammatory cytokines including thymic stromal lymphopoietin, interleukin (IL)-$1{\beta}$, IL-6, IL-8, and tumor necrosis factor-${\alpha}$ in activated HMC-1 cells. BT also decreased the activation of mitogen-activated protein kinases, nuclear factor-${\kappa}B$, and caspapase-1. Taken together, these results indicate that BT has potential as a regulator of inflammatory reactions for the treatment of arthritis such as osteoarthritis and rheumatoid arthritis.

  • https://doi.org/10.5667/tang.2013.0010 인용 PDF KSCI

Improvement in Diagnostic Accuracy of Hemangioma and Vascular Malformation through Multidisciplinary Clinic (협력진료를 통한 혈관종 및 혈관기형 진단 정확도 향상)

  • Kang, Kyung-Dong;Bae, Yong-Chan;Nam, Su-Bong;Choi, Soo-Jong;Jung, Do-Sang;Kim, Chang-Won
    • Archives of Plastic Surgery
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    • 제37권6호
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    • pp.758-762
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    • 2010

  • Purpose: It is difficult to provide accurate diagnosis and proper treatment for vascular anomalies, because vascular anomalies have a wide spectrum of lesion with various symptoms. Furthermore, vascular anomalies often require the services of a wide range of specialists. So, many patients have been discouraged by the lack of expertise and treatment options available to them. In this study, we aimed to describe the scope of the Vascular Malformation clinic (VAM clinic), a multidisciplinary clinic for hemangioma and vascular malformation patients and investigate of diagnostic accuracy of VAM clinic. Methods: 68 patients have included in a retrospective, medical record review study in the VAM clinic from may 2002 to august 2009. Data included the types of diagnoses of patients seen in the clinic, locations of lesions, comparison of accuracy of diagnoses at other clinic and initial diagnoses at VAM clinic and types of recommended treatments. Results: Initial diagnosis at VAM clinic showed 94.2% accuracy, while diagnosis at other clinic only showed 12.5% accuracy. Head and neck is most frequently occurred lesions in patients of VAM clinic. And VAM clinic is able to provide various and proper treatments to patients. Conclusion: Hemangiomas and vascular malformations can present with various medical problems. VAM clinic, the multidisciplinary clinic provided accurate diagnoses and proper treatments to patients.

  • PDF KSCI