• Title/Summary/Keyword: Korean Society of Radiation Oncology

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P53 OVEREXPRESSION AND OUTCOME OF RADIOTHERAPY IN HEAD & NECK CANCERS

  • Kim, In-Ah;Choi, Ihl-Bhong;Kang, Ki-Mun;Choi, Byung-Ok;Kim, Kyung-Mi;Park, Kyung-Shin;Cho, Seong-Ho;Kim, Hyung-Tae;Kim, Young-Shin;Kang, Chang-Suk
    • Proceedings of the Korean Biophysical Society Conference
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    • 1999.06a
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    • pp.70-70
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    • 1999
  • Experimental studies have implicated the wild type p53 in cellular response to radiation. Whether altered p53 function can lead to changes in clinical radiocurability remains an area of ongoing study. This study was performed to investigate whether any correlation between change of p53 and outcome of curative radiation therapy in patients with head and neck cancers.(omitted)

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Extraordinary radiation super-sensitivity accompanying with sorafenib combination therapy: what lies beneath?

  • Lee, Jayoung;Lee, Ju Hye;Yoon, Hanbin;Lee, Ho Jeong;Jeon, Hosang;Nam, Jiho
    • Radiation Oncology Journal
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    • v.35 no.2
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    • pp.185-188
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    • 2017
  • Primary liver tumor, especially hepatocellular carcinoma (HCC), is a common cause of cancer death worldwide. The incidence is generally higher in Asian countries than in western countries. Carcinogenesis of HCC is often associated with hepatitis viral infections. Current standard treatment of HCC is surgical resection or transplantation in patients with early stage disease. However, the patient with advanced stage disease, surgical resection is often limited. Sorafenib or other treatment modalities are not so effective as well. We report a case of unusual radiation super-sensitivity in advanced stage HCC, and review the literature.