• Asia-Pacific Journal of Business Venturing and Entrepreneurship
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• v.10 no.2
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• pp.11-16
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• 2015

A lot of factor effects on the enterprise's innovation and business performance, for instance CEO and members intention etc.. Niehoff et al. says, The success factors of innovation enterprise's management lead to members of vision, innovation, innovation activities and support for an aggressive attitude of the enterprise members. However, today's products consumers wanted diverse and complex needs. CEO and members of the enterprise has been the diversity effort. The increase cost savings as well as in the profit improve factors that enterprise's participated a education and training, Subgroup activities, process quality, eliminate waste, improve yields, lead time reduction, process capability increasing, ets. This paper is a report of an empirical survey performed to 277 small and medium-sized enterprise in the korea. Cronbach's alpha coefficient is employed to analyze the reliability of the data. The effect analysis of each group is performed by the SEM(structural equation model). We use the SPSS' Amos program to analyze the equation modeling and test the hypotheses of the model.

• Molecules and Cells
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• v.27 no.1
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• pp.113-118
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• 2009

In this study, we have shown the transcriptional regulation of the human GD3 synthase (hST8Sia I) induced by valproic acid (VPA) in human neuroblastoma SK-N-BE(2)-C cells. To elucidate the mechanism underlying the regulation of hST8Sia I gene expression in VPA-stimulated SK-N-BE(2)-C cells, we characterized the promoter region of the hST8Sia I gene. Functional analysis of the 5'-flanking region of the hST8Sia I gene by the transient expression method showed that the -1146 to -646 region, which contains putative binding sites for transcription factors c-Ets-1, CREB, AP-1 and NF-${\kappa}B$, functions as the VPA-inducible promoter of hST8Sia I in SK-N-BE(2)-C cells. Site-directed mutagenesis and electrophoretic mobility shift assay indicated that the NF-${\kappa}B$ binding site at -731 to -722 was crucial for the VPA-induced expression of hST8Sia I in SK-N-BE(2)-C cells. In addition, the transcriptional activity of hST8Sia I induced by VPA in SK-N-BE(2)-C cells was strongly inhibited by SP600125, which is a c-Jun N-terminal kinase (JNK) inhibitor, and $G{\ddot{O}}6976$, which is a protein kinase C (PKC) inhibitor, as determined by RT-PCR (reverse transcription-polymerase chain reaction) and luciferase assays. These results suggest that VPA markedly modulated transcriptional regulation of hST8Sia I gene expression through PKC/JNK signal pathways in SK-N-BE(2)-C cells.

• Explosives and Blasting
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• v.8 no.1
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• pp.3-16
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• 1990

The cautious blasting works had been used with emulsion explosion electric M/S delay caps. Drill depth was from 3m to 6m with Crawler Drill $\varphi{70mm}$ on the calcalious sand stone(sort-moderate-semi hard Rock). The total numbers of feet blast were 88. Scale distance were induces 15.52-60.32. It was applied to propagation Law in blasting vibration as follows. Propagtion Law in Blasting Vibration $V=K(\frac{D}{W^b})^n$ where V : Peak partical velocity(cm/sec) D : Distance between explosion and recording sites (m) W : Maximum Charge per delay-period of eighit milliseconds or more(Kg) K : Ground transmission constant, empirically determind on th Rocks, Explosive and drilling pattern ets. b : Charge exponents n : Reduced exponents Where the quantity $D/W^b$ is known as the Scale distance. Above equation is worked by the U.S Bureau of Mines to determine peak particle velocity. The propagation Law can be catagrorized in three graups. Cabic root Scaling charge per delay Square root Scaling of charge per delay Site-specific Scaling of charge per delay Charge and reduction exponents carried out by multiple regressional analysis. It's divided into under loom and over loom distance because the frequency is verified by the distance from blast site. Empirical equation of cautious blasting vibration is as follows. Over 30m----under l00m----- $V=41(D/3\sqrt{W})^{-1.41}$ -----A Over l00m-----$V= 121(D/3\sqrt{W})^{-1.66}$-----B K value on the above equation has to be more specified for furthur understang about the effect of explosives, Rock strength. And Drilling pattern on the vibration levels, it is necessary to carry out more tests.

• Atmosphere
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• v.27 no.4
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• pp.385-398
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• 2017

Numerical weather prediction experiments were carried out by applying topographic effects to reduce or enhance the solar radiation by terrain. In this study, x and ${\kappa}({\phi}_o,\;{\theta}_o)$ are precalculated for topographic effect on high resolution numerical weather prediction (NWP) with 1 km spatial resolution, and meteorological variables are analyzed through the numerical experiments. For the numerical simulations, cases were selected in winter (CASE 1) and summer (CASE 2). In the CASE 2, topographic effect was observed on the southward surface to enhance the solar energy reaching the surface, and enhance surface temperature and temperature at 2 m. Especially, the surface temperature is changed sensitively due to the change of the solar energy on the surface, but the change of the precipitation is difficult to match of topographic effect. As a result of the verification using Korea Meteorological Administration (KMA) Automated Weather System (AWS) data on Seoul metropolitan area, the topographic effect is very weak in the winter case. In the CASE 1, the improvement of accuracy was numerically confirmed by decreasing the bias and RMSE (Root mean square error) of temperature at 2 m, wind speed at 10 m and relative humidity. However, the accuracy of rainfall prediction (Threat score (TS), BIAS, equitable threat score (ETS)) with topographic effect is decreased compared to without topographic effect. It is analyzed that the topographic effect improves the solar radiation on surface and affect the enhancements of surface temperature, 2 meter temperature, wind speed, and PBL height.

• Environmental and Resource Economics Review
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• v.23 no.4
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• pp.747-784
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• 2014

Many countries have implemented a variety of climate and energy policies to reduce greenhouse gas emissions and expand renewable energy production. The ultimate goals of those policies are associated with transition to a low-carbon economy that aims to combat climate change and economic growth. This study aims to examine empirically if the countries which implement overlapping climate policies and renewable energy policies show additional reduction of the GHG emissions than the countries which implement single climate or renewable energy policy. The result shows that overlapping policies contribute to reduce additional GHG but not all cases. In particular, only overlapping policies mixing 'ETS and RPS(renewable portfolio standards)' and 'Carbon Tax and FIT(Feed-in Tariff)' can lead to additional reduction of GHG emissions.

• Journal of Advanced Navigation Technology
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• v.13 no.1
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• pp.68-73
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• 2009

Recently, various services through the Internet are gradually increased and developed. The traditional way of examination has been replacing by the online test as well. The most representative is the IBT TOEFL by the ETS in the US. Besides this, a lot of online tests and some related discussions are very fierce to carry out due to the continuous increase of the number of exam candidates. Taking account of the economic issues compared to the previous test, this online method has a lot of strengths. This paper aims to build an online test system based on the 3- tier browser-server architecture, which is different from the commonly used 2-tier based system. This system was achieved using the Visual Studio.Net 2005 and SQL Server 2000 as development tools, and based on the ASP.NET 2.0 platform, using the ADO.NET and C# language.

• Environmental and Resource Economics Review
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• v.24 no.4
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• pp.607-627
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• 2015

As observed and experienced in EU ETS, allowance price volatility is one of major concerns in decision making process for $CO_2$ abatement investment. The problem of linearly non-separable profits functions could emerge when one power company holds several power plants with different technology specifications. Under this circumstance, conventional analytical solution for investment option is no longer available, thereby calling for the development of numerical analysis. This paper attempts to develop a Monte-Carlo least squares model to analyze investment options for power companies under emission trading scheme regulations. Stochastic allowance price is considered, and simulation is performed to verify model performance.

• Explosives and Blasting
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• v.9 no.4
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• pp.3-12
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• 1991

The cautious blasting works had been used with emulsion explosion electric M /S delay caps. Drill depth was from 3m to 6m with Crawler Drill 70mm on the calcalious sand stone (soft-moderate-semi hard Rock) . The total numbers of feet blast were 88. Scale distance were induces 15.52-60.32. It was applied to Propagation Law in blasting vibration as follows .Propagtion Law in Blasting Vibration V=k(D/W/sup b/)/sup n/ where V : Peak partical velocity(cm/sec) D : Distance between explosion and recording sites(m) W ; Maximum Charge per delay -period of eight milliseconds or more(Kg) K : Ground transmission constant, empirically determind on the Rocks, Explosive and drilling pattern ets. b : Charge exponents n : Reduced exponents Where the quantity D/W/sup b/ is known as the Scale distance. Above equation is worked by the U.S Bureau of Mines to determine peak particle velocity. The propagation Law can be catagrorized in three groups. Cabic root Scaling charge per delay Square root Scaling of charge per delay Site-specific Scaling of charge delay Charge and reduction exponents carried out by multiple regressional analysis. It's divided into under loom and over loom distance because the frequency is varified by the distance from blast site. Empirical equation of cautious blasting vibration is as follows. Over 30m--under 100m----V=41(D/ W)/sup -1.41/-----A Over l00m---------V=121(D/ W)/sup -1.56/-----B K value on the above equation has to be more specified for furthur understand about the effect of explosives. Rock strength, And Drilling pattern on the vibration levels, it is necessary to carry out more tests.

• Journal of the Korea Society of Computer and Information
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• v.19 no.2
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• pp.253-261
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• 2014

Recently as the focal point of interdisciplinary integration of learner's key competencies have been increased, it was the real solution to avoid excessive curriculum and reconfiguration of curriculum to provide actual learning opportunities. The purpose of this paper was to investigate information subject-centered inclusive education strategies for 21st century key competencies extension by Delphi study. As a result by a total 3 round Delphi method, information subject-centered curriculum integration for key competencies extension was to understand why they should be integrated and what can makes it com true. This elicited the consensual agreements of experts about information subject-centered curriculum integration aims, methods, contents, and evaluations ets. As a result, this study offers strategies of information subject-centered curriculum integration applicable to elementary and middle schools.

• Environmental Mutagens and Carcinogens
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• v.25 no.1
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• pp.40-46
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• 2005

2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) displays high toxicity in animals and has been implicated in human carcinogenesis. Although the mechanism of carcinogenesis by TCDD is unclear, it is considered to be a non-genotoxic compound and tumor promoter. In our experiment, we investigated the effects of TCDD on gene expression in mouse skin carcinogenesis. We used cDNA microarray to detect the differential gene expression in tumors induced in hairless mouse skin by MNNG plus TCDD protocol. We found that erb-2, c-ets2 and p27$^{kip1}$ were significantly up-regulated, but TNFR2, AKT-l, integrin $\beta$l, maspin, IGF-l, c-raf-l, Rb were significantly down-regulated, in tumor region, respectively. We also found that the expression of 53 genes involved in cen cycle, signal transduction, apoptosis, adhesion molecule, angiogenesis, and invasion, were changed two fold more, in tumor surrounding region. These data suggest that TCDD alters the expression of a large array of genes involved in apoptosis, cytokine production and angiogenesis in mouse skin carcinogenesis.