• The Journal of Advanced Prosthodontics
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• v.8 no.3
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• pp.172-180
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• 2016

PURPOSE. The purpose of this study was to analyze the antimicrobial, antioxidant activity and cytotoxicity of Dendropanax morbifera $L{\acute{e}}veille$ extract for assessing whether Dendropanax morbifera $L{\acute{e}}veille$ can be used for the development of natural mouthwash and denture cleaning solution. MATERIALS AND METHODS. The extract was obtained from branches of Dendropanax morbifera $L{\acute{e}}veille$. The solvent fractions were acquired by fractionating Dendropanax morbifera $L{\acute{e}}veille$ extract using n-hexane, ethyl acetate, chloroform and butanol solvent. Paper disc test was used to evaluate the antimicrobial and antifungal activity of Dendropanax morbifera $L{\acute{e}}veille$ extract and solvent fractions against Streptococcus mutans and Candida albicans. The analysis of antioxidant activity was carried out through DPPH radical scavenging assay. The cytotoxicity of Dendropanax morbifera $L{\acute{e}}veille$ extract was analyzed through MTT assay using normal human oral keratinocytes. RESULTS. Dendropanax morbifera $L{\acute{e}}veille$ extract showed antimicrobial activity against Streptococcus mutans and especially Candida albicans. The solvent fractions of Dendropanax morbifera $L{\acute{e}}veille$ showed strong antimicrobial activity against Streptococcus mutans and Candida albicans in n-hexane and butanol solvent fraction, respectively. Dendropanax morbifera $L{\acute{e}}veille$ extract also showed outstanding antioxidant activity. Butanol, ethyl acetate, and chloroform solvent fraction of Dendropanax morbifera $L{\acute{e}}veille$ tended to have increased antioxidant activity as the concentration increased. Dendropanax morbifera $L{\acute{e}}veille$ extract showed high cell survival rate in cytotoxicity test. CONCLUSION. Dendropanax morbifera $L{\acute{e}}veille$ extract turned out to have antimicrobial, antioxidant activity and cytophilicity. Based on these results, it is expected that Dendropanax morbifera $L{\acute{e}}veille$ is applicable as an ingredient for natural mouthwash and denture cleanser.

• Journal of the Korean Society of Clothing and Textiles
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• v.48 no.4
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• pp.673-687
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• 2024

In this study, we first analyzed the total polyphenol and flavonoid contents and the antioxidant activity of Dendropanax morbiferus extracts obtained from different parts using different solvents. We then investigated the possibility of producing Dendropanax morbiferus leaf extract loaded polyurethane (PU) nanofibers via electrospinning. The total polyphenol and flavonoid content and the antioxidant activity of the Dendropanax morbiferus leaf extracts obtained distilled water were found to be higher than those of the extracts obtained under other conditions, and it was therefore used to prepare the extracts/PU nanofibers by varying the concentrations of both the Dendropanax morbiferus leaf extract and PU. The most appropriate fiber morphology were when 1.5% and 1.0% of the Dendropanax morbiferus leaf extracts were added to 12% and 13% PU, respectively. Fourier-tranform infrared (FT-IR) spectroscopy and X-ray diffraction (XRD) analyse reveal the successful incorporation of the Dendropanax morbiferus leaf extracts into the PU matrix. In addition, the nanofibers containing this leaf extract were confirmed to exhibit antibacterial properties against Staphylococcus aureus, suggesting the potential usefulness of nanofacial masks containing the Dendropanax morbiferus leaf extract.

• Journal of Life Science
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• v.26 no.11
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• pp.1341-1344
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• 2016

Dendropanax morbifera is an endemic tree species of Korea, it is restricted to the southern parts of Korea. The internal transcribed spacer (ITS) region of nuclear ribosomal DNA (nrDNA) for Dendropanax morbifera grown at Bogil-do, Korea was determined. We investigated the sequence-based phylogenetic relationships of plants related and clarified its taxonomical position. The determined sequences consisted of 689 residues. ITS1 was 222 bp long while ITS2 was 233 bp long. The 5.8S rDNA was 160 bp long. The ITS region sequences of the Dendropanax species included in this study were obtained from GenBank. Oreopanax polycephalus was used as the outgroup. A pairwise alignment was calculated using the Clustal X program. A phylogenetic tree was constructed by the neighbor-joining method using the Tree view program. Sequence similarities among species including D. morbifera Bogil-do isolate showed the range 92.6 to 99.7% in sequence-based phylogenetic analysis using total 615 base pairs of ITS1, 5.8S rDNA and ITS2. D. morbifera Bogil-do isolate exhibited the highest degree of relatedness to D. chevalieri, sharing 99.7% ITS region similarity. D. morbifera Bogil-do isolate also showed to D. trifidus, sharing 99.4% ITS region similarity.

• Korean Journal of Environmental Biology
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• v.28 no.1
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• pp.30-39
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• 2010

We researched community structure, species composition, and habitat environment of Dendropanax morbifera populations distributed in Goheung, Haenam, Wando (I.), and Bogildo (I.) at south coast of the Korean Peninsula. Our research was also estimated possible area for growth of Dendropanax morbifera by analyzing meteorological factors of the habitat thereof. Dendropanax morbifera community divided into Castanopsis cuspidata var. sieboldii group and Carpinus laxiflora group by difference of species composition. Broad-leaved evergreens showed high dominance value in view of rNCD in Dendropanax morbifera community as follows: Camellia japonica (100.0), Quercus acuta (88.6), Castanopsis cuspidata var. sieboldii (55.8), Dendropanax morbifera Lev. (41.4), Trachelospermum asiaticum var. intermedium (23.8), Eurya japonica (19.9) and Ligustrum japonicum (11.5). In the population distribution, 94.2% of Carpinus laxiflora group consisted of sapling and small size class that are less than 5 cm in DBH while 54.2% of Castanopsis cuspidata var. sieboldii group did. The soil environment of habitat showed low soil acidity, good organic matter and water content, and good drainage. The distribution area of Dendropanax morifera habitat had $13^{\circ}C$ or more in annual mean temperature, $7.4^{\circ}C$ or more in daily minimum temperature, $100^{\circ}C$ month or more in warmth index, and approximately 1,344 mm in mean annual precipitation. Dendropanax morifera habitat corresponded to evergreen broad-leaved forest zone located in islands and coast in the southwest region of the Korean Peninsula. The northern limit line of Dendropanax morifera community was determined as Gunsan-Jeongeup-Gwangju-Jinju-Pohang-Youngdeok line based on $13^{\circ}C$ in annual mean temperature that was confirmed in natural habitat of Dendropanax morifera community.

• Proceedings of the Botanical Society of Korea Conference
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• 1999.04a
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• pp.5-5
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• 1999

• Particle and aerosol research
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• v.18 no.2
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• pp.37-50
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• 2022

Due to the syndrome coronavirus 2 (SARS-CoV-2) pandemic, the subway passenger cabin should be continuously sterilized. However, a disinfectant such as chlorine is toxic and can lead to different issues to human health. In this paper, we introduced a novel disinfectant based on natural product (Dendropanax morbifera extract). Via ultra-high performance liquid chromatography - mass spectrometer (UHPLC-MS), different compounds from Dendropanax morbifera extract showed antivirus potentials. Antimicrobial experiments confirmed that the air-disinfectant containing Dendropanax morbifera can eliminate harmful microorganisms including Gram (-), Gram (+), and yeast within 5 mins. The as-prepared air-disinfectant also showed high antivirus activity against H1N1, HRV, and EV71. Deodorization test also indicates that the as-prepared air-disinfectant can lower the harmful gas such as ammonia and trimethylamine in the atmosphere. To evaluate the potential of air-disinfectant containing Dendropanax morbifera in practical applications, different safety tests including acute oral toxicity, acute skin irritation, and eye irritation were conducted. Results showed that the as-prepared disinfectant did not negatively affect tested animals during these safety investigations.

• Korean Journal of Medicinal Crop Science
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• v.26 no.2
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• pp.181-187
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• 2018

Background: This study aimed to investigate out the influence of drought stress on the physiological responses of Dendropanax morbifera seedlings. Methods and Results: Drought stress was induced by discontinuing water supply for 30 days. Under drought stress, photosynthetic activity was significantly reduced with decreasing soil water content (SWC), as revealed by the parameters such as Fv/Fm, maximum photosynthetic rate ($P_{N\;max}$), stomatal conductance ($g_s$), stomatal transpiration rate (E), and intercellular $CO_2$ concentration (Ci). However, water use efficiency (WUE) was increased by 2.5 times because of the decrease in $g_s$ to reduce transpiration. Particularly, E and $g_s$ were remarkably decreased when water was withheld for 21 days at 6.2% of SWC. Dendropanax morbifera leaves showed osmotic adjustment of -0.30 MPa at full turgor and -0.13 MPa at zero turgor. In contrast, the maximum bulk modulus of elasticity ($E_{max}$) did not change significantly. Thus, Dendropanax morbifera seedlings could tolerate drought stress via osmotic adjustment. Conclusions: Drought avoidance mechanisms of D. morbifera involve reduction in water loss from plants, through the control of stomatal transpiration, and reduction in cellular osmotic potential. Notably photosynthetic activity was remarkably reduced, to approximately 6% of the SWC.

• Journal of the Korea Furniture Society
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• v.14 no.2
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• pp.13-20
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• 2003

This research is to develop kiln-drying schedules for 2.7 mm thick boards of Neolitsea sericea and Dendropanax morbifera, which grow in the southern region of Korean Peninsula. These two species are lesser-known to woodcraft industry in this country. The proper USDA drying schedules for Neolitsea sericea and Dendropanax morbifera were found to be T10-C6 and T10-E6, respectively, by using the Quick Oven-drying Method. The boards dried in a kiln with the newly-developed schedules were revealed to be free from warping and checking.

• Journal of Oriental Neuropsychiatry
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• v.30 no.4
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• pp.341-355
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• 2019

Objectives: The purpose of this study was to check the therapeutic effect of the Dendropanax morbifera Pharmacopuncture for insomnia and cognition caused by psychosocial stress. Methods: We separated Wistar rats (older than age 10 weeks, 300 g) into normal, control, positive control (Zolpidem administered, PC), and Dendropanax morbifera Pharmacopuncture experimental groups (DPA). Psychosocial stress such as circadian rhythm change, clammy straw, predator stress, restraint stress, noise bursts, and flashing lights were applied to the control, PC, DPA groups. The Dendropanax morbifera Pharmacopuncture group was given 0.5×, 1× and 2× amount concentration of Dendropanax morbifera Pharmacopuncture, respectively. The levels of Melatonin, Serotonin, Corticosterone, GABA, BDNF and CREB were measured, and the Y-maze test, weight and blood test were performed. Results: In all of the DPA groups, the Melatonin level showed no noticeable difference. In the DPA-2x group, Serotonin increased significantly. In all the experimental groups, Corticosterone decreased significantly and GABA showed increasing tendency. The DPA-1x and DPA-2x groups showed remarkable increase in BDNF and DPA-0.5x and the DPA-2x groups showed significant increase in CREB. The DPA-2x group showed remarkable increase in the Alternation behavior category of the Y-maze test. In all of the experimental groups the weight change showed increasing tendency, whereas no noticeable differences were found among all experimental groups regarding AST, ALT, BUN, Creatinine and CBC. Conclusions: Dendropanax morbifera Pharmacopuncture increases levels of serotonin and GABA, decreases corticosterone, increases levels of BDNF and CREB, and increases the ratio of alternation behavior in the Y-maze test. Thus, I suggest that Dendropanax morbifera Pharmacopuncture has the effect of treating insomnia caused by psychosocial stress, activating the brain, and improving cognition.

• Korean Journal of Plant Resources
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• v.31 no.1
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• pp.10-15
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• 2018

The leaves and stems of Dendropanax morbiferus were separated from organic solvents with methanol. The organic solvent fractions were fractionated with dichloromethane, ethyl acetate and butanol according to the systematic fractionation method. Oxidation in the body induces aging, and antioxidant activity has attracted the attention of many people as a preventive component to suppress negative reactions in the body. To investigate the antioxidant activity of Dendropanax morbiferus were subjected to DPPH free radical assay. In addition, acetyl cholinesterase inhibitions were performed for Alzheimer's disease as an aging neurological disease. As a result, it was confirmed that the antioxidant effect of DPPH was generally good in the antioxidant test. The ethyl acetate fractions of Dendropanax morbiferus stems and leaves were $IC_{50}=30{\mu}g/m{\ell}$. Acetyl cholinesterase inhibition experiments were carried out at a concentration of $250{\mu}g/m{\ell}$. Dendropanax morbiferus stems fractions showed dichloromethane fraction of 57.68%, which significantly inhibited the activity of acetyl cholinesterase.