• Journal of Korean society of Dental Hygiene
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• v.14 no.4
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• pp.479-484
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• 2014

Objectives : The aim of the study is to investigate the oral health knowledge, attitude and dental caries experience in Korean 12-year-old adolescents. Methods : The subjects were 2,196 adolescents living in Seosan, with an average age of 12.2 years. Data were collected using a self-administered questionnaire from April 10 through June 10, 2011. A trained investigator made an oral examination of them in natural light, using a mirror and an explorer to determine their DMFT index. Results : The prevalence rate of dental caries of adolescents was 59.1%. The DMFT index of the subjects was 1.98, which was lower than the national mean of 2.2 for the same age. The DMFT index was significantly higher in the female(2.25) than the male group(1.72). The attitude of oral health was positively related to DMFT index in this study(OR=1.25; CI=1.01-1.54). It appears that knowledge and attitude concerning oral health, among young Korean 12-year-old adolescents living in Seosan, are in need of improvement. Conclusions : Based on the findings, dental caries experience is associated with attitude of oral health. This result suggests that the implementation of oral health promotion should be considered for various factors related to attitude of oral health in adolescents.

• The Journal of Korea Assosiation for Disability and Oral Health
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• v.1 no.1
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• pp.18-24
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• 2005

The purposes of this study were 1) to investigate the oral health problem of the disabled according to the handicapped types, 2) to collect the empirical data for developing and establishing the oral health policies for the handicapped, and 3) to find out the major obstacles against the dental services and oral health promotion. The handicapped subjects were collected by designed cluster sampling and interviewed with structured questionnaire in order to measure the oral health knowledge and behaviors. The subjects were attending the special schools and private or public welfare institutions for crippled disorder, encephalopathy disorder, mental retardation, visual disturbance, hearing defect, and developmental disorder. Oral examination was conducted by 13 trained dentists. 1,476 of handicapped people were finally surveyed. The results were as follows; The experiences of visiting dental office during the last one year in 18~64 year-old disabled people were 48.86% in crippled disorder, 52.50% in mental retardation, 58.24% in visual disturbance, 39.29% in hearing defect, respectively. To improve this challenging situation, we should find out the obstacles against the dental service and oral hygiene maintenance by the types of handicap, and develop the oral health policies which could support and advocate the Korean disabled.

• The Korean Journal of Health Service Management
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• v.2 no.1
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• pp.155-165
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• 2008

This study is aims finding out characteristics and change levels of medical advertizing between before and after revised medical laws. We investigated to medical advertizing of 3 major newspaper(Josen, Joongang, Donga) to achieve study purpose. After revised medical laws, major change is seen below. 1. Increase rates of medical advertizing was 65.5%. Specially, increase rates of medical advertizing by each department were differently each department; Dermatology was 450%, dentist's clinic was 342%, orthopedic surgery was 171%, and plastic surgery was 133%. In spite of increasing trends of most departments, urology decreased to 50% than before revised medical laws. 2. Of types of medical advertizing, Question and Answer type increased to 230% than before. Illegal level of medical advertizing was 10.4%. 3. The contents of medical advertizing were hospital location, photograph before and after treatments, and carrier, name and introduction of medical staffs. 4. The size of medical advertizing increased 1.73 column then before. The size of medical advertizing in clinics was shown statistically increase than hospital level. With above results, it is cleared that increase rates and trends of medical advertizing are more increased and complicated before revised medical laws. We try to be better situations for patients to get more exactly information and facts.

• Journal of Arbitration Studies
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• v.27 no.4
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• pp.61-72
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• 2017

In this study, the Commission proposed the mitigation of remedies by improving the role of medical disputes and preventing medical disputes. Medical disputes include a comprehensive description of medical malpractice, medical negligence, medical malpractice, and medical malpractice. Medical negligence refers to the neglect of medical care due to careless medical care in the treatment of patients, leading to patient injury and death. An inappropriate response in the process of international treatment could result in international trials and a decline in international credibility. In cases where medical disputes arise, health care is strictly necessary to determine the truth or absence of medical malpractice, and these expertise and experience are usually provided by emotion. With the neutral and objective emotions provided fairly and impartially, medical care expertise and experience can be fair, and the medical disputes can be resolved peacefully if the parties are trustworthy. The Health Care Dispute Mediation Committee should focus on enhancing the professionalism, objectivity, and reliability of medical care.

• Parasites, Hosts and Diseases
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• v.55 no.3
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• pp.313-317
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• 2017

Paragonimiasis is a parasitic disease caused by Paragnonimus species. The primary site of infection is the lung, and extrapulmonary involvement is also reported. When infected with Paragonimus westermani, which is the dominant species in Korea, the central nervous system is frequently involved along with the liver, intestine, peritoneal cavity, retroperitoneum, and abdominal wall. Ectopic paragonimiasis raises diagnostic challenge since it is uncommon and may be confused with malignancy or other inflammatory diseases. Here, we report an ectopic paragonimiasis case initially presented with recurrent abdominal pain. The patient developed abdominal pain 3 times for the previous 3 years and the computed tomography (CT) of the abdomen revealed fluid collection with wall enhancement. Recurrent diverticulitis was initially suspected and part of the ascending colon was resected. However, the specimen showed intact colon wall without evidence of diverticulitis and multiple parasite eggs and granulomas were found instead. The size of about $70{\mu}m$, the presence of an operculum and relatively thick egg shell suggested eggs of Paragonimus species. With appropriate exposure history and a positive antibody test, the definitive diagnosis was made as peritoneal paragonimiasis.

• Parasites, Hosts and Diseases
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• v.59 no.3
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• pp.189-225
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• 2021

The use of albendazole and mebendazole, i.e., benzimidazole broad-spectrum anthelmintics, in treatment of parasitic infections, as well as cancers, is briefly reviewed. These drugs are known to block the microtubule systems of parasites and mammalian cells leading to inhibition of glucose uptake and transport and finally cell death. Eventually they exhibit ovicidal, larvicidal, and vermicidal effects on parasites, and tumoricidal effects on hosts. Albendazole and mebendazole are most frequently prescribed for treatment of intestinal nematode infections (ascariasis, hookworm infections, trichuriasis, strongyloidiasis, and enterobiasis) and can also be used for intestinal tapeworm infections (taeniases and hymenolepiasis). However, these drugs also exhibit considerable therapeutic effects against tissue nematode/cestode infections (visceral, ocular, neural, and cutaneous larva migrans, anisakiasis, trichinosis, hepatic and intestinal capillariasis, angiostrongyliasis, gnathostomiasis, gongylonemiasis, thelaziasis, dracunculiasis, cerebral and subcutaneous cysticercosis, and echinococcosis). Albendazole is also used for treatment of filarial infections (lymphatic filariasis, onchocerciasis, loiasis, mansonellosis, and dirofilariasis) alone or in combination with other drugs, such as ivermectin or diethylcarbamazine. Albendazole was tried even for treatment of trematode (fascioliasis, clonorchiasis, opisthorchiasis, and intestinal fluke infections) and protozoan infections (giardiasis, vaginal trichomoniasis, cryptosporidiosis, and microsporidiosis). These drugs are generally safe with few side effects; however, when they are used for prolonged time (>14-28 days) or even only 1 time, liver toxicity and other side reactions may occur. In hookworms, Trichuris trichiura, possibly Ascaris lumbricoides, Wuchereria bancrofti, and Giardia sp., there are emerging issues of drug resistance. It is of particular note that albendazole and mebendazole have been repositioned as promising anti-cancer drugs. These drugs have been shown to be active in vitro and in vivo (animals) against liver, lung, ovary, prostate, colorectal, breast, head and neck cancers, and melanoma. Two clinical reports for albendazole and 2 case reports for mebendazole have revealed promising effects of these drugs in human patients having variable types of cancers. However, because of the toxicity of albendazole, for example, neutropenia due to myelosuppression, if high doses are used for a prolonged time, mebendazole is currently more popularly used than albendazole in anti-cancer clinical trials.

• Biomedical Science Letters
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• v.19 no.2
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• pp.124-131
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• 2013

Genome-wide association studies (GWAS) have identified a number of common variants associated with serum liver enzyme homeostasis in population. In the previous study, single nucleotide polymorphisms (SNPs) in several genes have been reported to be associated with serum liver enzyme levels in European population. We aimed to confirm whether the genetic variation of SMAD2 (SMAD family member 2) gene influence the serum liver enzyme levels in Korean population. We genotyped variants in or near SMAD2 in a population-based sample including 994 unrelated Korean adult. Here, we performed association analysis to elucidate the possible relations of genetic polymorphisms in SMAD2 gene with serum liver enzyme levels. By examining genotype data of a total of 944 subjects in 5 hospital health promotion center, we discovered the SMAD2 gene polymorphisms are associated with serum liver enzyme levels. The common and highest significant polymorphism was rs17736760 (${\beta}$=3.51, P=5.31E-07) with glutamic oxaloacetic transferase (GOT), rs17736760 (${\beta}$=5.99, P=1.25E-05) with glutamic pyruvate transaminase (GPT), and rs17736760 (${\beta}$=15.68, P=9.93E-07) with gamma glutamyl transferase (GGT) in all group. Furthermore, the SNP rs17736760 was consistently associated with GOT (${\beta}$=5.25, P=1.72E-06), GPT (${\beta}$=9.97, P=1.16E-05), GGT (${\beta}$=26.13, P=3.43E-06) in men group. Consequently, we found statistically significant SNP in SMAD2 gene that are associated with serum levels of GOT, GPT, and GGT. In addition, these results suggest that the individuals with the minor alleles of the SNP in the SMAD2 gene may be more elevated serum liver enzyme levels in the Korean population.

• Journal of Industrial Convergence
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• v.20 no.10
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• pp.95-101
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• 2022

The purpose of this study is to determine the association between physical activity and anxiety levels in Korean adolescents after COVID-19 Pandemic. This study performed a secondary analysis of the 16th Korea Youth Risk Behavior Survey 2020. Complex-sample descriptive statistics and the chi-square test were used for data analysis in SPSS 27. As a result, 60.9% of adolescents engaged in physical activity for more than 60 minutes a day and 39.1% of those did not. The level of anxiety among adolescents was found to be mild anxiety at 22.2%, moderate anxiety at 7.6%, and severe anxiety at 3.6%. A significant association was found between physical activity and anxiety levels (p <.001). Therefore, there should be a plan to increase physical activity in the national policy for the promotion of youth mental health.

• Journal of Korean society of Dental Hygiene
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• v.22 no.5
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• pp.333-340
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• 2022

Objectives: This study aimed to confirm the association between cognitive function and oral health status in the elderly. Methods: In this study, 5,794 respondents, aged 55 or older, who had participated in the 7th aging research panel survey were used. Statistical analyses were performed using a complex samples cross-tabulation analysis, complex samples general linear model, and a complex sample multinomial logistic regression analysis. Results: After analyzing the cognitive function of the elderly according to their oral health conditions, it was found that suspicions of dementia (19.6%) and cognitive function decline (25.9%) were more common for those who wore dentures than for those who did not wear dentures (p<0.001). Compared to those who did not wear dentures, those who wore dentures were linked to a 1.665 times higher suspicion of dementia (p<0.001). In comparison, cognitive decline was 0.964 times lower when the number of natural teeth increased by 1, and it was 0.941 times lower when the oral health evaluation index for the elderly increased by 1 point (p<0.001). Conclusions: As a result of this study, it was confirmed that cognitive function and oral health status are related in the elderly. Therefore, systematic measures for oral health management and oral health promotion should be prepared in tandem with awareness of possible cognitive decline in the elderly.

• The Journal of the Korea Contents Association
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• v.15 no.6
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• pp.337-345
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• 2015

Korea worker is well known for its long work and amongst employees and to change un-healthy lifestyle. This study aims to investigate the association between health behaviors and sleep problems in employees. It employed data from the Third Korean Working Conditions Survey (KWCS). The total number of individuals included in the analysis was 34,788 employees, from the 2011 survey. The outcome was sleep problems, which had a prevalence rate of 2.5% in men and 2.3% in women. An adjusted odds ratios were as follows: 2.26(1.75-2.91) for hypertension, 2.21(1.60-3.06) for obesity, 26.82(21.51-33.45) for depression and 2.02(1.64-2.49) for high level of job stress. We need to invest to identify relevant and various health service promotion for sleep problem that un-healthy workers want will use.