• Title/Summary/Keyword: Korea national park

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Embryotoxicity of Ochratoxin A in Cultured Rat Embryonic Midbrain Cells and Whole Embryos (흰쥐 배양 전배자 및 중뇌세포에서 Ochratoxin A의 독성)

  • Hong, Jin-Tae;Park, Kui-Lea;Han, Soon-Young;Park, Ki-Sook;Kim, Hyung-SIk;Oh, Se-Dong;Park, Hee-Jung;Lee, Rhee-Da;Jang, Seung-Jae
    • YAKHAK HOEJI
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    • v.42 no.3
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    • pp.336-344
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    • 1998
  • Effects of ochratoxin A (OTA) on embryo development were studied in cultured whole embryos from 9.5 day gestation rat for 48 h. OTA (more than $0.5{\mu}g/ml$) induced microcephaly in the cultured rat whole embryos. Protein and DNA content, and DNA synthesis were significantly inhibited by OTA. We next examined whether the microcephaly seen in cultured whole embryo partially results from inhibition of differentiation of embryonic midbrain cells. Embryonic midbrain cells were extracted from 12 day gestation rat embryos, and cultured for 96 hr. OTA ibhibited cell differentiation about 50% over control. We also tested whether OTA-induced embryotoxicity would be associated with oxidative damages. We measured the ${\gamma}$-glutamyltranspeptidase (${\gamma}$-GT) and glutathione peroxidase (GPX) activities, and glutathione (GSH) content in both cultured whole embryos and embryonic midbrain cells. OTA decreased GSH content, whereas slightly increased ${\gamma}$-GT activity, but GPX activity was not significantly changed. These results show that OTA caused the microcephaly and its effect may be partially due to the inhibition of cell differentiation of embryonic midbrain cells, but the role of oxidative damages is not clear in embryotoxicity.

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13 Weeks Repeated-Dose Toxicity Studies of the Siho(Bupleuri Radix) in Rats

  • Myung Sil Hwang;Dong Han Shin;Young Na Yum;Jin Hong Ahn;Jun Chul Park;Ji Sun Lee;Yun Jin Park;Ji On Kim;Shin Hee Kim
    • Proceedings of the Korean Society of Toxicology Conference
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    • 2003.05a
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    • pp.55-55
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    • 2003
  • The Bupleuri Radix, called as "Siho" in Korea has been widely used in Korea, China, and Japan as Traditional Herbal Medicine since ancient times and currently. Although saikosaponins isolated from the Bupleuri Radix had metabolic and anti-inflammatory action, it's toxicity was not screened completely. Recently, many herbal medicines are imported from China but safety of these was not evaluated. (omitted) (omitted)

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Discriminatian of Cnidium Rhizame using PCR-mediated RFLP

  • Cho, So-Yean;Ze, Keum-Ryon;Seong, Rack-Seon;Lee, Jong-Pill;Ju, Young-Park;Park, Sang-Yong;Jung, Young-Ja;Cho, Chang-Hee;Ha, Kwang-Won;Suh, Young-Bae
    • Proceedings of the PSK Conference
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    • 2002.10a
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    • pp.367.2-367.2
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    • 2002
  • Cnidium Rhizome is a frequently prescribed herbal medicine in Korea, Japan as well as China, which has been successfully used in these countries for the treatment of diseases related to. gynecology, blood circulations and dental troublers in the name of 천궁. And it is circulated as the same chinese character, which is 천궁, although original plants are different as Cnidium officinale in pharmacopoeia of Korea or Japan and Ligusticum chuanxiong Hort. In that of China. (omitted)

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A Study on Actual Condition of Damaged Korean Fir(Abies koreana) Caused by Rodents and Identifying Suspected Species in Seseokpyeongjeon Area of Jirisan National Park (지리산국립공원 세석평전 일대 설치류에 의한 구상나무 피해실태 및 가해 의심종 구명)

  • Park, Hong-chul;Kim, Hye-ri;Kim, Ji-young;Kim, Hyeon-ho;Heo, Deok-gyeong;Lee, Ho
    • Korean Journal of Environment and Ecology
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    • v.34 no.3
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    • pp.198-206
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    • 2020
  • The purpose of this study was to investigate the damage caused by rodents in the area around Seseokpyeongjeon in Jirisan National Park and identify suspected perpetrating species by analyzing rodent excrement found near the damaged trees. Damaged trees were surveyed regardless of species of trees in the exploration trail in the target site where visual observation was possible. Sequencing analysis of mitochondrial DNA Cyt-b was performed on rodent excrement around the damaged trees to identify the perpetrating species. A total of 52 trees were damaged by rodents, and they were all identified to be Korean Fir (Abies koreana) and were concentrated in places where Korean Fir formed communities with high density. A total of 40 Korean Fir over 1.5 meters high were surveyed, and only the affected branches, not the whole tree, were found to be withered in 39 of them. A total of 12 Korean Fir under 1.5 meters high were surveyed, and 7 of which were found to have been completely withered, indicating that relatively young trees were more vulnerable to withering. The genetic sequencing analysis of excrement confirmed that the species that perpetrated the Korean Fir was Craseomys regulus.

Three Unrecorded Endophytic Fungal Species Isolated from Plants in Taean-gun, Korea

  • Jae-Eui Cha;Hyeok Park;Jae-Wook Choi;Seok-Yong Park;Ahn-Heum Eom
    • The Korean Journal of Mycology
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    • v.51 no.3
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    • pp.229-237
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    • 2023
  • In the present study, we isolated endophytic fungi from different tissues of two plants, Pseudosasa japonica and Quercus serrata from Taean-gun, Korea. Morphological characteristics of the isolated fungal strains were observed. We identified the fungi based on the phylogenetic analysis using DNA sequences from the region of internal transcribed spacer, large subunit rDNA, β-tubulin, and translation elongation factor 1-α DNA. Three endophytic fungi that were not previously recorded in Korea, namely Geomyces asperulatus, Leptoxyphium fumago, and Tubakia oblongispora were identified. Here, we describe the morphological characteristics of these unrecorded fungi and present the results of the phylogenetic analysis.