• Tuberculosis and Respiratory Diseases
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• v.56 no.1
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• pp.91-96
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• 2004

Primary lung cancer frequently metastasizes to distant organs. But breast is a very rare site of metastasis. So, accurate diagnosis is essential to rule out primary breast cancer. A 62-year old woman who had complained of cough was diagnosed as small cell lung carcinoma of the right lower lobe. She had a 2.5cm sized lobular mass in left upper mid portion of breast. Sonoguided breast biopsy revealed small cell carcinoma consistent with metastatis from primary lung cancer. She also had bone metastses to the scapula and the vertebrae. We report the case of metastatic breast cancer from small cell lung carcinoma.

• The Korea Journal of Herbology
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• v.27 no.6
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• pp.115-122
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• 2012

Objectives : This study evaluated activities and ingredient contents concerning extracts according to extraction solvents of Insampaedok-san (IS, Renshen bai du-san). Methods : The herbal constituents of IS were extracted with water and 70% ethanol at $100^{\circ}C$ for 2 hr. Using the HPLC system, the six ingredient contents of different solvent extracts of IS were analyzed. The nitric oxide (NO), prostaglandin $E_2$ ($PGE_2$) production and proinflammatory cytokines were measured in RAW264.7 cells stimulated with lipopolysaccharide (LPS). The macrophage-derived chemokine (MDC/CCL22) and regulated on activation normal T-cell expression and secreted (RANTES/CCL5) production were measured in HaCaT and BEAS-2B cells stimulated tumor necrosis factor-${\alpha}$ (TNF-${\alpha}$) and interferon-${\gamma}$ (IFN-${\gamma}$). The activities of glycerol-3-phosphate dehydrogenase (GPDH) and leptin level were measured in 3T3-L1 cells. Results : The calibration curves showed good linearity ($r^2$=1.0000) for different concentration ranges. The contents of liquiritin, naringin, hesperidin, neohesperirin and glycyrrizin in 70% ethanol extracts of IS were relatively higher than that of water extract, however the content of ferulic acid in 70% ethanol and water extract of IS were similar. The extraction solvents of water and 70% ethanol were evaluated inhibitory effect on the production of NO, $PGE_2$, TNF-${\alpha}$ and IL-6 in RAW 264.7 cells. Their extractions were inhibitory effect on production of MDC/CCL22 and RANTES/CCL5 in HaCaT cell and BEAS-2B cell, respectively. In addition, evaluated reduced on GPDH activity and leptin level in 3T3-L1 preadipocyte cell. Conclusions : Our results suggest that IS extracts were inhibitory effects of disease such as inflammation, allergies and obesity.

• Korean Journal of Oriental Medicine
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• v.16 no.2
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• pp.43-55
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• 2010

Objective : There is a growing interest on Complementary and Alternative Medicine(CAM). But the term 'CAM' often causes confusion, for the perception of CAM is determined by how the relationship between CAM and Conventional Medicine is established. Methods : In this paper, we researched the concept of CAM through the change in the terminology and definition of CAM throughout history. Furthermore, we also analyzed related papers in Korea. Results : International studies show that the relationship between Conventional Medicine and CAM has become more cooperative. Meanwhile, in Korea, Korean Medicine is categorized as a type of Conventional Medicine, not CAM. Conclusion : Though Korean Medicine is included in Conventional Medicine in Korea, the research methodology is still restricted in ways of bio-medical science. Further study on the original research method of Korean Medicine is needed.

• Journal of Physiology & Pathology in Korean Medicine
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• v.21 no.1
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• pp.263-269
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• 2007

In Korea, Korean Medicine is the first choice in treating stroke. Because stroke prognosis, risk of recurrence, and choices for management are influenced by stroke subtype, correct analysis of stroke subtype is important. Until now, the studies on differentiation of the symptoms and signs for the stroke were a few and the Korean standard differentiation of the symptoms and signs for the stroke don't exist. To develop the Korean standard differentiation of the symptoms and signs for the stroke, we go through subtype of stroke in traditional chinese medicine, Korean Medicine, western medicine.

• The Korean Journal of Nuclear Medicine
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• v.35 no.3
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• pp.125-130
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• 2001

• 대한예방의학회:학술대회논문집
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• 2002.10a
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• pp.180-180
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• 2002

• 대한예방의학회:학술대회논문집
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• 2002.10a
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• pp.497-497
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• 2002

• 대한예방의학회:학술대회논문집
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• 2000.10a
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• pp.308-309
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• 2000

• 대한예방의학회:학술대회논문집
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• 2001.10a
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• pp.450-451
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• 2001

• 대한예방의학회:학술대회논문집
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• 2001.10a
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• pp.335-336
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• 2001