• Pediatric Infection and Vaccine
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• v.15 no.2
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• pp.115-120
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• 2008

Purpose : This post-marketing surveillance (PMS) study was conducted in Korea to assess the safety and reactogenicity of hepatitis A vaccine (GlaxoSmithKlineBiologicals'$Havrix^{TM}$) administered to the Korean population. Methods : A total of 1,188 healthy subjects with 1,122 subjects <6 years of age were enrolled to receive one dose of the hepatitis A vaccine from April 2005 to January 2006. Diary cards were provided to the subjects or subjects' parents for reporting solicited and unsolicited symptoms during the 4-day and 31-day post-vaccination follow-up period. Results : The number of subjects who returned diary cards was 568, whereas, 620 subjects did not return diary cards. Among the subjects who returned diary cards, 9.9% and 14.3% reported local and general solicited/unsolicited symptoms. Among the subjects who did not return diary cards, 1.6% and 8.4% reported local and general solicited/unsolicited symptoms. At least one unsolicited symptom was reported by 13.2% of the subjects. Conclusion : Results indicate that the vaccine was well-tolerated and had an acceptable safety profile. The use of diary cards in such a survey provided a prompt and reliable option for recording symptoms.

• Pediatric Infection and Vaccine
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• v.27 no.2
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• pp.83-89
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• 2020

Purpose: Group A streptococcus (GAS) is a common pathogen in pediatric patients and often causes acute pharyngotonsillitis and skin and soft tissue infections. In addition, bacteremia with significant morbidity and mortality can also occur. This study was conducted to describe the clinical manifestations and treatment outcomes of pediatric GAS bacteremia patients in Korea. Methods: This was a single-center, retrospective study. From January 2000 to December 2016, pediatric patients aged ≤18 years with GAS bacteremia were studied. Clinical manifestations, underlying diseases, intensive care unit stay, and antibiotic susceptibility were evaluated. Results: During the study period, 19 patients had GAS bacteremia. Ten (53%) were male, and the median age was 7.4 years (range, 0.3-17.4 years). Fourteen (74%) had chronic underlying diseases. Five (26%) were immunocompromised (leukemia and chronic kidney disease). Eight (42%) had lymphatic or vascular malformations, of which seven had lesions with signs of inflammation. Three (16%) developed pneumonia, and two of them received ventilator care. The 30-day mortality rate was 6% (1/19), and the cause of death was bacteremic pneumonia. All GAS isolates were sensitive to penicillin. Fifteen (79%) were sensitive to both erythromycin and clindamycin. Conclusions: This study identified various clinical manifestations of GAS bacteremia. GAS should be considered as a potential pathogen that can cause bacteremia and result in a serious clinical course.

• Applied Chemistry for Engineering
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• v.27 no.3
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• pp.227-238
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• 2016

This review article highlights different types of nano-sized catalysts for the selective alcohol oxidation to form aldehydes (or ketones) with supported or immobilized metal nanoparticles. Metal nanoparticle catalysts are obtained through dispersing metal nanoparticles over a solid support with a large surface area. The nanocatalysts have wide technological applications to industrial and academic fields such as organic synthesis, fuel cells, biodiesel production, oil cracking, energy conversion and storage, medicine, water treatment, solid rocket propellants, chemicals and dyes. One of main reactions for the nanocatalyst is an aerobic oxidation of alcohols to produce important intermediates for various applications. The oxidation of alcohols by supported nanocatalysts including gold, palladium, ruthenium, and vanadium is very economical, green and environmentally benign reaction leading to decrease byproducts and reduce the cost of reagents as opposed to stoichiometric reactions. In addition, the room temperature alcohol oxidation using nanocatalysts is introduced.

• Journal of fish pathology
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• v.30 no.2
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• pp.79-88
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• 2017

At the present, fish farms are suffering a lot of economic losses due to infectious diseases caused by various pathogens including aeromonad. Aeromonad is ubiquitous bacteria that causes infectious diseases. At least 26 species in the genus Aeromonas have been reported to cause fatal infections not only in salmonid fishes, but also in other freshwater and seawater fishes. Molecular techniques based on nucleic acid sequences of 16S rDNA and housekeeping genes can be used to identify the Aeromonas species. In this study, The genus Aeromonas was isolated from salmonid fishes of sixteen fish farms in Gangwon-Do, Korea and phylogenetically identified based on the sequences of 16S rDNA and housekeeping genes for Aeromonad, i.e. RNA polymerase sigma factor ${\sigma}^{70}$ (rpoD) or DNA gyrase subunit B (gyrB). Consequently, 96 strains were collected from Atlantic salmon (Salmo salar), coho salmon (Oncorhynchus kisutch), masou salmon (Oncorhynchus masou) and rainbow trout (Oncorhynchus mykiss), and 36 isolates were identified as the genus Aeromonas by 16S rDNA analysis. Thirty six Aeromonad isolates were further analysed based on rpoD or gyrB gene sequences and found Aeromonas salmonicida (24 isolates), A. sobria (10 isolates), A. media (1 isolates) and A. popoffii (1 isolates), indicating that A. salmonicida is a main infectious bacteria in Salmonid fishes in Gangwon-Do. It was also proved that the phylogenetic identification of Aeromonas species based on the sequences of housekeeping gene is more precise than the 16S rDNA sequence.

• Korean Journal of Food Science and Technology
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• v.38 no.5
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• pp.720-723
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• 2006

The viability of Shigella sonnei, a significant cause of gastroenteritis in Korea, on TSA plates was determined after sublethal heating treatments and NaCl treatments. In addition, recovery levels of sublethally injured cells on TSA plates containing different concentrations of NaCl (TSAS) were investigated. The viability decreased significantly with increasing degree of sublethal heating treatments, but increases in NaCI treatment concentration from 0 to 6% had little effect on the viability. After being sublethally treated at $55^{\circ}C$ for 30 min, bacterial populations were reduced by 7.58, 7.83 and 7.93 log CFU/mL on 2, 4, and 6% TSAS, respectively. After being sublethally treated at $60^{\circ}C$ for 30 min, bacterial populations were reduced by 6.71, 6.73, and 6.73 log CFU/mL on 2, 4 and 6% TSAS, respectively. Decimal reduction times (D-values) decreased with increasing NaCl treatment concentrations after sublethal heating at 55 or $60^{\circ}C$. These data imply that the S. sonnei cells sublethally injured by insufficient heating processes had a lower recovery rate with increasing NaCl concentrations in the recovery media.

• The Korean Journal of Malacology
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• v.28 no.4
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• pp.321-328
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• 2012

Light and transmission electron microscopy of Batillus cornutus hemocytes revealed differences that the morphological distinctions between blast-like cell, granulocytes and hyalinocytes. Base on the morphological characteristics of the cells, we identified the eight types of hemocytes and present a categorization of the hyalinocytes into six sub-categories. The hemocytes of B. cornutus were observed basophilic cell under the light microscopy. Blast-like cells had a spherical profile with a central nucleus filling almost the whole cell. Granulocytes were characterized by presenting variable numbers of granules. This cell had spherical shape with diameter 7 ${\mu}m$ and smooth endoplasmic reticula, granules, mitochondria, glycogen granules in the cytoplasm. Hyalinocytes were the most abundant cell type. Especially, hyalinocyte VI had iirregular an amoebal shape and observed autophagosome and heterophagosome in the cytoplasm. From these results, it is concluded that there are eight types of cells in the hemolymph of B. cornutus. Further studies are now needed to identify the role of these hemocytes in the enzymological and immunological response.

• The Korean Journal of Malacology
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• v.25 no.2
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• pp.145-151
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• 2009

The ultrastructural changes in germ cells during oogenesis of the melania snail, Semisulcospira libertina libertina have been investigated by light and electron microscopy. The ovary is located on the surface of the hepatopancreas in the spiral posterior region. The ovary exhibited greenish color in the gonadal mature season. The ovary was composed of a number of oogenic follicles. Oogenesis was divided into five stages with histological features: (1) oogonia, (2) previtellogenic, (3) initial vitellogenic, (4) active vitellogenic, and (5) mature stages. Oogonia were oval in shape, $4-6\;{\mu}m$ in diameter, and had a large nucleus. Previtellogenic oocytes were about $20\;{\mu}m$ in diameter and the cytoplasm reacted with hematoxylin in H-E satin. Initial vitellogenic stage, oocytes were $60-80\;{\mu}m$ in diameter, and small yolk granules of low electron density are scattered in the cytoplasm. Oocytes in the initial vitellogenic stage were connected with ovarian follicle by egg stalk. Active vitellogenic oocyte were $100-120\;{\mu}m$ in diameter. Electron density, size and quantity of yolk granules that are distributed in the cytoplasm have increased from the previous stage. Result of TEM observations, the oocyte contains well-developed Golgi complex, endoplasmic reticula and tubular mitochondria in the cytoplasm. Cytoplasm of mature oocyte was filled with proteinaceous yolk globules of high electron density. In this stage, the length of microvilli in the egg envelope was approximately $1.1\;{\mu}m$.

• Women's Health Nursing
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• v.4 no.2
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• pp.187-202
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• 1998

This study was carried out to identify the difference between educational needs and levels of satisfaction of primigravida during the antepartum period. The goal of the study was to obtain data needed to develope educational programs and to improve the nursing quality for antepartal clients. The subjects were 106 primigravida who attend antenatal clinic at 3 general hospitals in the Seoul area. The data was gathered using a questionnaire which, consist of 71 items, was developed by the researcher from May 4 to June 3, 1998. Results found are as follows : 1. The characteristics of subjects : The majority of subjects were aged 25-29 years(73.6%), college graduates(61.3%), jobless(68.9%), had no religion(38.7%), attended antenatal clinic regularly(91.5%), duration of pregnancy was 38-39 weeks(49.06%), pregnancy was planned(67%), and 42.5% have had some sort of prenatal education. 2. Over all level of educational needs was relatively high(Mn. 3.97) but the level of satisfaction was of average level(Mn. 3.01). Therefore, differences between the level of educational needs and satisfaction was significant(P=.0001). 3. The educational needs by category, the highest need was on birth preparation(Mn. 4.18), self care of the mother and infant care(Mn 4.10), health maintenance and promotion(Mn. 3.79), the lowest was care of discomfort(Mn 3.66). The level of satisfaction was higher on postpartum self care(Mn 3.15), but the lowest was infant care(Mn 2.84). Differences between educational needs and satisfaction by categories was significant(P=.0001). 4. Relationship between educational needs and levels of satisfaction among primigravida of different characteristics were as follows : 1) Educational needs of minor discomforts area were significantly high among age of 25-29(P=.0108), and over 35 years of age, was satisfied on preparation of labor & delivery, postpartum self care (P=.036, .02). 2) With regard to different level of education, middle school graduates had higher educational needs on discomfort care and postpartum self care(P=.0014, .014). College graduates have had higher educational needs on health maintenance(P=.008) and were more satisfied on preparation of birth(P=.0025) 3) With regard to whether pregnancy was planned or not, no difference was found on educational needs. But the levels of satisfaction was significantly higher in the group of planned pregnancy(discomfort care P=.0454, birth preparation P=.0256, postpartum self care P=.0092). 4) with regard to antenatal education, those who have had some sort of antenatal education, educational needs on birth preparation(P=.0345) was significantly high. And also the levels of satisfaction were significantly higher on every category(P=.0004-.0001). 5) No difference was found on educational needs or level of satisfaction by Job, religions, regularity of antenatal care and complication of pregnancy.

• Anxiety and mood
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• v.11 no.2
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• pp.91-105
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• 2015

Objectives : After disaster, some people develop posttraumatic stress sequelae such as posttraumatic stress disorder (PTSD), major depression, substance use disorders, and suicide. To date, numerous screening and assessment tools for behavioral health issues including mental health problems, psychosocial maladjustment and status of recovery after disaster have been developed. In this condition, one of important topics is to choose instruments that can quickly and accurately measure the issues. Methods : This article reviewed several self-reported scales in adults for disaster behavioral health, which were searched using academic search engines like PubMed, Scopus, KoreaMed and KISS from the earliest available date of indexing through January 31, 2015. Results : More than 40 eligible instruments evaluating the disaster behavioral health issues containing posttraumatic stress sequelae, psychological and social resources, non-disaster stress, and general functions were presented in terms of availability, effectiveness, and expeditiousness. Also, we introduced basic frame aiming on practical usage, which includes standard version and brief version of the instruments for disaster behavioral health. Conclusion : We suggest the accessibility and the applicability of assessment instruments for disaster behavioral health. The systemic review of this article will provide further directions for them.

• The Journal of the Institute of Internet, Broadcasting and Communication
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• v.16 no.5
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• pp.143-149
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• 2016

Recent accidents caused by toxic chemicals and the social problems caused by frequent. As of 2010, there are more than 100,000 types of deadly toxic chemicals being distributed throughout Korea, and severely intoxicated patients along with an enormous number of patients can be induced at the time of an accident involving deadly toxic chemicals. Internationally, the seriousness of large-scale disasters due to a NBC disaster (nuclear, biologic and chemical disaster) is being highlighted as well. So, we obtain the information of the RFID tag attached to a glass bottle with containing the toxic chemical to transfer the data to the smart device has been studied a system that can monitor the status of the toxic chemical in real time. The proposed system is the information was sent to the main system using a zigbee communication by recognizing the tag vial containing the toxic chemical with the 13.56MHz bandwidths good permeability. User may check the information in real time by utilizing the smart device. However, the error of the system for managing the toxic chemical generates a result that can not be predicted. Failure of the system was detecting the error by using a comparator as this can cause an error. And the detected error proposed a duplex system so that they do not affect the overall system.