• 제목/요약/키워드: Korea Research Institute of Chemical Technology

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Piperoctadecalindine, a New Piperidine Alkaloid from Piper retrofractum Fruits

  • Ahn Jong Woong;Lee Chong Ock;Kim Eun Joo;Zee Ok Pyo;Kim Hyung Jin
    • Bulletin of the Korean Chemical Society
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    • 제13권4호
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    • pp.388-391
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    • 1992

  • A chemical investigation of the fruits of Piper retrofractum (Piperaceae) has led to the isolation and characterization of a novel piperidine alkaloid, piperoctadecalidine together with three known alkaloids piperine, pipernonaline and guineensine. The structure of the new compound was detemined to be (2E,4E,14Z)-N-(2,4,14-Octadecatrienoyl) piperidine by spectral and synthetic methods.

  • https://doi.org/10.5012/bkcs.1992.13.4.388 인용 PDF

Role of metabolism by flavin-containing monooxygenase in thioacetamide-induced immunosuppression

  • Lee, Jeong W.;Ki D. Shin;Shin W. Cha;Kim, Jong-C.;Kim, Eun J.;Sang S. Han;Tae C. Jeong;Woo S. Koh
    • 한국독성학회:학술대회논문집
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    • 한국독성학회 2001년도 International Symposium on Signal transduction in Toxicology
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    • pp.121-121
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    • 2001

  • Thioacetamide has been known to cause immune suppression. In this report we studied the role of metabolic activation by flavin-containing monooxygenase in the thioacetamide-induced immune response. To determine whether the metabolites of thioacetamide produced by flavin-containing monooxygenase result in the immunosuppression, methimazole, a flavin-containing monooxygenase inhibitor, was used to block the flavin-containing monooxygenase pathway.(omitted)

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