• Journal of Pharmaceutical Investigation
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• v.36 no.5
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• pp.343-348
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• 2006

The purpose of the present study was to evaluate the bioequivalence of two zolpidem tartrate tablets, Stilnox tablet(Sanofi-aventis Korea, reference product) and Zanilo tablet(ChoDang Pharm Co., Ltd., Korea, test product), according to the guidelines of Korea Food and Drug Administration(KFDA). After adding an internal standard(cimetropium), 250 ${\mu}L$ plasma samples were extracted using 1.3 mL of ethyl acetate. Extracted compounds were analyzed by HPLC with triple-quadrupole mass spectrometry. This method for determination of zolpidem is proved accurate and reproducible with the limit of quantitation of 1 ng/mL in human plasma. Twenty-four healthy male Korean volunteers received each medicine at the zolpidem tartrate dose of 10 mg in a $2{\times}2$ crossover study. There was one-week washout period between the doses. Plasma concentrations of zolpidem were monitored for over a period of 8 hr after the administration. $AUC_{0-t}$(the area under the plasma concentration-time curve) was calculated by the linear trapezoidal rule. $C_{max}$(maximum plasma drug concentration) and $T_{max}$(time to reach $C_{max}$) were compiled from the plasma concentration-time data. Analysis of variance was carried out using logarithmically transformed $AUC_{0-t}$ and $C_{max}$. No significant sequence effect was found for all of the bio-availability parameters indicating that the crossover design was properly performed. The 90% confidence intervals for the log transformed data were acceptable range of log 0.8 to log 1.25(e.g., log 0.92-log 1.06 for $AUC_{0-t}$, log 0.96-log 1.13 for $C_{max}$). The major parameters, $AUC_{0-t}$ and $C_{max}$ met the criteria of KFDA for bioequivalence indicating that Zanilo tablet is bioequivalent to Stilnox tablet.

• Journal of the Korea Society for Simulation
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• v.21 no.1
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• pp.81-88
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• 2012

In the M&S filed, The Battle Lab is available for acquisition, design, development tool, validation test, and training in the weapon system of development process. Recently, the Battle Lab in the military of Korea is still in an early stage, in spite of importance of battle lab construction. In the environment of network centric warfare, a practical use of the M&S which is connecting live, virtual and constructive model can be applied to all field of System Engineering process. It is necessary thar the Battle Lab is not restricted by time and space, and is possible for the technical implementation. In this paper, to guarantee the interoperability of live and virtual simulation, virtual simulators connect live simulators by using the tactical data link. To guarantee the interoperability of virtual and constructive simulation, both virtual simulators and constructive simulators use the RTI which is the standard tool of M&S. We propose the System that constructed the Air Defence Battle Lab. In case of the approach of target tracks, The Air Defence Battle Lab is the system for the engagement based on a command of an upper system in the engagement weapon system. Constructive simulators which are target track, missile, radar, and launcher simulator connect virtual simulators which are MCRC, battalion, and fire control center simulators using the RPR-FOM 1.0 that is a kind of RTI FOM. The interoperability of virtual simulators and live simulators can be guaranteed by the connection of the tactical data links which are Link-11B and ATDL-1.

• Journal of Digital Convergence
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• v.16 no.7
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• pp.107-116
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• 2018

One of the key mission is to develop and prompte the use National Competency Standards, which is defined to be the systemization of competencies(knowledge, skills and attitudes) required to perform duties at the workplace by the nation for each industrial sector and level. This provides the basis for the design of training and detailed specifications for workplace assessment. To promote the data-driven service improvement, the commercial product Splunk was introduced, and has grown to become an extremely useful platform because it enables the users to search, collect, and organize data in a far more comprehensive, far less labor-intensive way than traditional databases. Leveraging Splunk's built-in data visualization and analytical features, HRD Korea have built custom tools to gain new insight and operational intelligence that organizations have never had before. This paper analyzes the NCS homepage. Concretely, applying Splunk in creating visualizations, dashboards and performing various functional and statistical analysis and structure without Web development skills. We presented practical use and implications through case studies.

• Journal of the Korea Institute of Information Security & Cryptology
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• v.24 no.2
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• pp.397-409
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• 2014

According to the Personal Information Protection Act(PIPA) which is legislated in March 2011, the individual or company that handles personal information, called Personal information processor, should encrypt some kinds of personal information kept in his Database. For convenience sake we call it DB Encryption in this paper. Law enforcement and the implementation agency accordingly are being strengthen the supervision that the status of DB Encryption is being properly applied and implemented as the PIPA. However, the process of DB Encryption is very complicate and difficult as well as there are many factors to consider in reality. For example, there are so many considerations and requirements in the process of DB Encryption like pre-analysis and design, real application and test, etc.. And also there are surely points to be considered in related system components, business process and time and costs. Like this, although there are plenty of factors significantly associated with DB Encryption, yet more concrete and realistic validation entry seems somewhat lacking. In this paper, we propose a realistic DB Encryption Assurance Framework that it is acceptable and resonable in the performance of the PIPA duty (the aspect of the individual or company) and standard direction of inspection and verification of DB Encryption (the aspect of law enforcement).

• Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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• 2009.10a
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• pp.599-601
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• 2009

In currently being adopted as a e-leaning standard, SCORM it is difficult to provide the customized contents to a learner by changing the learner's level at runtime, and to control selective studying. So, we designed and implemented the customized contents organization engine(CCOE) in order to complement SCORM's faults in this paper. The CCOE consists of a level evaluation module, a contents re-organization module and a question item selection module. A level evaluation module evaluates the learner's level based on a question item reaction theory. And a question item selection module selects some random items by each level or by considering the learner's level which is then provided to a studying before evaluation, a section evaluation, and a quiz. And then this module transmits the selected items to the contents reorganization module for providing the quiz. A contents re-organization module selects the customized contents based on the learner's level by searching the tagged difficulty to the content, and creates the sequence with the selected items and the transmitted items from the question item selection module. If proposed in this paper CCOE is applied, the higher effectiveness of learning is expected by providing the customized learning contents based on the re-evaluated learner's level by each section.

• Journal of Korea Trade
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• v.23 no.3
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• pp.68-83
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• 2019

Purpose - The UNCITRAL Model Law on Electronic Transferable Records (Model Law) is based on the principles of non-discrimination against the use of electronic means, functional equivalence, and technology neutrality underpinning all UNCITRAL texts on electronic commerce. Investigating the disagreements between the Model Law and the Koran Commercial Act (KC Act), including the B/L Regulation, and suggesting the revision of the KC Act including the B/L Regulation, could be a valuable study. The purpose of this paper is to contribute to the harmonization of Korean legislation regarding electronic bill of lading in compliance with the Model Law. Design/methodology - The Model Law is flexible to accommodate the use of all technologies and models, such as registries, tokens, and distributed ledgers: that is, blockchain. In 2007, the KC Act was revised to regulate electronic bills of lading to promote the widespread legal use of electronic bills of lading. In addition, The Regulation on Implementation of the Provisions of the Commercial Act Regarding Electronic Bills of Lading (the B/L Regulation) was enacted to regulate the detailed procedures in using electronic bills of lading in 2008. This paper employs a legal analysis by which this paper does find differences between two rules in light of technology neutrality and global standard of electronic bills of lading model. Findings - The main findings are as follows: i) the Korean registry agency has characteristics of a closed system. ii) The KC Act has no provision regarding control. iii) The KC Act discriminates other electronic bills of lading on the ground that it was issued or used abroad. Moreover, this study does comprehensive analysis of Korean Acts in comparison with the Model Law and, in particular, this study analyzes the differences between the KC Act and the Model Law by comparing article by article in view of the harmonization of the two rules. Originality/value - The subject of previous several studies was draft provisions on Electronic Transferable Records before completion of the Model Law; thus, these studies did not take into consideration the character of the Model Law as the Model Law was chosen at the final stage of legislation. This study is aimed at the final version of the Model Law. So, this study is meaningful by finding the suggestion and directions for the Korean government to revise the KC Act and the B/L Regulation in line with the Model Law.

• Korean Chemical Engineering Research
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• v.57 no.1
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• pp.42-50
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• 2019

As the industry develops in Korea, the use of hazardous chemicals is increasing rapidly and chemical accidents are increasing accordingly. Most of the chemical accidents are caused by leaks of hazardous chemicals, but there are also accidents in which all the substances are released instantaneously due to sudden high temperature/pressure or defection of the storage tanks. This is called catastrophic failure and its frequency is very low, but consequence is very huge when it occurs. In Korea, there were 15 casualties including three deaths due to catastrophic rupture of water tank in 2013, and 64 instances of failures from 1919 to 2004 worldwide. In case of catastrophic failure, it would be able to overflow outside the bund that reduces the evaporation rate and following consequence. This incident is called overtopping. Overseas, some researchers have been studying the amount of external overflow depending on bund conditions in the event of such an accident. Based on the previous research, this study identified overtopping fraction by condition of bund in accordance with Korea Chemicals Controls Act Using CFD simulation. As a result, as the height increases and the distance to the facility decreases while meeting the minimum standard of the bund capacity, the overtopping effect has decreased. In addition, by identifying the effects of overtopping according to atmospheric conditions, types of materials and shapes of bunds, this study proposes the design of the bund considering the effect of overtopping caused by catastrophic failure with different bund conditions.

• Journal of the Korea Institute of Information and Communication Engineering
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• v.23 no.3
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• pp.341-348
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• 2019

In this paper, a monopole type antenna applicable to WLAN and WiMAX standard frequency bands is designed and fabricated. The proposed antenna is designed to have rectangular ring and rectangular patch based on microstrip feeding for triple band characteristics and inserted two stub in the top of the rectangular ring patch to enhance impedance bandwidth characteristics. The proposed antenna has $18.0mm(2W_1+W_2){\times}33.0mm(L_7+L_8+L_9)$ on a dielectric substrate of $27.0mm(W_1){\times}44mm(L_1){\times}1.0mm$ size. From the fabrication and measurement results, impedance bandwidths of 660MHz (2,08 to 2.74GHz) for 2.4/2.5MHz band, 488MHz (3.40 to 3.88GHz) for 3.5MHz band, and 2,180MHz (4.61 to 6.79GHz) for 5,000MHz band were obtained based on the impedance bandwidth. The proposed antenna also obtained the measured gain and radiation pattern in the anechoic chamber.

• Journal of Korean Tunnelling and Underground Space Association
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• v.21 no.1
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• pp.127-136
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• 2019

Tunnel construction by TBMs should be supported by the performance of a screw conveyor in order to obtain the optimum penetration rate, so studies related to the screw conveyor performance have been being conducted. Compared to the study on the performance of the screw conveyor for the soil, however, the research on the performance of the screw conveyor for the rock is insufficient. Considering the domestic tunnel sites with more rock layers than soil layers, simulation of discharge of 6 types of rock chips by the screw conveyor was conducted using DEM. Regardless of the shape and volume of the rock chips, the discharge rates of the rock chips by the parallel placed screw conveyor at a speed of 10 RPM in the same rock mass were about 20% (standard deviation: 1.3%) of the maximum volume of discharge rate by the screw conveyor. It is expected that this study can be used as a reference material for screw conveyor design and operation in TBM excavations in rock masses.

• The Journal of the Korea Contents Association
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• v.21 no.4
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• pp.77-87
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• 2021

Smart Factory refers to a factory that can be controlled by itself with an intelligent factory that improves productivity, quality and customer satisfaction by combining the entire process of manufacturing and production with digital automation solutions. The manufacturing industry around the world is rapidly changing, with Germany, Europe, and the United States at the center. In order to cope with such changes, the Korean government is also implementing a policy to spread the supply of smart factories for small and medium-sized companies, and related ministries and agencies such as the Ministry of Commerce, Industry and Energy, the Ministry of SMEs and Venture Business, the Korea Institute of Technology and Information Promotion, and local technoparks, as well as large companies such as Samsung, SK and LG are actively investing in smart manufacturing projects to support smart factories[1]. Factory Automation (FA) construction has many issues regarding the connection of heterogeneous equipment. The most difficult aspect of configuring various communications from various equipment is the reason. Although it may not be known if there are standards or products made up of the same company, it is not easy to build equipment that is old, up-to-date, and different use environments through a series of communications. To solve this problem, we would like to propose a method of communication using Modbus, one of FieldBus, which is one of the many industrial devices of PLC, a representative facility control system, and is used as a communication standard.