• Title/Summary/Keyword: Knowledges

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Basic Principles of Drug Interaction (약물상호작용의 원리와 의의)

  • Chun, Boe-Gwun
    • Korean Journal of Biological Psychiatry
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    • v.7 no.1
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    • pp.3-13
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    • 2000
  • There is nothing that is harmless ; the dose alone decides that something is no poison(Paracelsus, 1493-1541). So, in a point of view to maximize the therapeutic efficacy of drug therapy in a way that minimize the drug toxicity, the knowledges of the drug-ineractions as well as the pharmacokinetic and pharmacodynamic principles of every therapeutic drug used in the medical clinic cannot be emphasized too much. Many drug interactions can be predicted if the pharmacokinetic properties, pharmacodynamic mechanisms of action of the interacting drugs are known, and most adverse interactions can be avoided. In this paper, the clinical importance, classification, and general principles of clinical drug-interactions are presentated with a few explanatory examples.

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A Study on the Characteristic of the Inductively Coupled $SF_6$ Plasma (유도 결합형 $SF_6$플라즈마 특성에 관한연구)

  • Ha, Jang-Ho;Jun, Yong-Woo;Song, Hyun-Jig;Park, Won-Zoo;Lee, Kwang-Sik;Lee, Dong-In
    • Proceedings of the KIEE Conference
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    • 1999.11d
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    • pp.1111-1113
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    • 1999
  • This paper represents the characteristic analysis for the etching in $SF_6$ plasma and the plasma itself, based on the specific knowledges on the discharge mechanism of $SF_6$ plasma which is widely used for the applications of dry etching, using Radio Frequency Inductively Coupled Plasma (RFICP) by measuring electron density, electron temperature then observing their relationship to find the effect of discharge mechanism of $SF_6$ plasma to the etching in contrast to the existing method of finding optimal discharge condition by heuristic.

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PSA: A Photon Search Algorithm

  • Liu, Yongli;Li, Renjie
    • Journal of Information Processing Systems
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    • v.16 no.2
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    • pp.478-493
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    • 2020
  • We designed a new meta-heuristic algorithm named Photon Search Algorithm (PSA) in this paper, which is motivated by photon properties in the field of physics. The physical knowledge involved in this paper includes three main concepts: Principle of Constancy of Light Velocity, Uncertainty Principle and Pauli Exclusion Principle. Based on these physical knowledges, we developed mathematical formulations and models of the proposed algorithm. Moreover, in order to confirm the convergence capability of the algorithm proposed, we compared it with 7 unimodal benchmark functions and 23 multimodal benchmark functions. Experimental results indicate that PSA has better global convergence and higher searching efficiency. Although the performance of the algorithm in solving the optimal solution of certain functions is slightly inferior to that of the existing heuristic algorithm, it is better than the existing algorithm in solving most functions. On balance, PSA has relatively better convergence performance than the existing metaheuristic algorithms.

The Optimal Design of HFC by means of GAs (유전자 알고리즘을 이용한 HFC의 최적설계)

  • 이대근;오성권;장성환
    • 제어로봇시스템학회:학술대회논문집
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    • 2000.10a
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    • pp.369-369
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    • 2000
  • Control system by means of fuzzy theory has demonstrated its robustness in applying to the high-order and nonlinear dynamic system in that it can utilizes the human expert knowledges in system design. In this paper, first, the design methodology of HFC combined PID controller with fuzzy controller by membership function of weighting coefficient is proposed. Second, Second, an auto-tuning algorithms utilizing the simplified reasoning method and genetic algorithms is presented to improve the performance of hybrid fuzzy controller. Especially, in order to obtain the optimal scaling factors and PID parameters of HFC using GA based on advanced initial individual, three kinds of estimation modes such as basic, contraction, and expansion mode are effectively utilized. The proposed HFC is evaluated and discussed in ITAE, overshoot and rising time to show applicability and superiority with simulation results.

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스테이터 및 로터의 블랭킹에 관한 자동화된 공정설계 및 금형설계 시스템

  • Choi, Jae-Chan;Kim, Byung-Min;Kim, Chul;Lee, Seung-Min
    • Proceedings of the Korean Society of Precision Engineering Conference
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    • 1994.10a
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    • pp.642-647
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    • 1994
  • This paper describes some research works of computer-aided design of blanking & piercing progressive die for stator and rotor parts by the press. An approach to the system is based on knowledge based rules. The developed system is composed of five main modules such as input & graphic interface, blanking feasibility check, strip layout, die layout and output module. Using this system, design parameters (geometric shapes, die generated in dimensions and dimensions of tool elements) are determined and output is generated in graphic form. Knowledges for tool design are extracted from the plasticity theories, handbooks, relevent references and empirical know-hows of experts in blanking companies. The developed system provides powerful capabilities for process planning and die design of stator and rotor parts.

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An Automated Process Planning and Die Design System for Blanking of Stator and Rotor Parts (스테이터 및 로터의 블랭킹에 관한 공정설계 및 금형설계 시스템)

  • Park, J.C.;Kim, M.M.;Lee, S.M.
    • Journal of the Korean Society for Precision Engineering
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    • v.13 no.8
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    • pp.40-51
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    • 1996
  • This paper describes some research works of computer-aided design of blanking and piercing progressive die for stator and rotor parts. An approach to the system is based on knowledge based rules. The deveolped system is composed of six modules such as main program, input and shape treatment, production feasibility check, strip layout, die layout and drawing edit module. Using this system, design parameters ( geometric shapes, die and punch dimensions and dimensions of tool elements) are determined and output is gen- erated in graphic from. Knowledges for tool design are extracted from the plasticity theories, handbooks, relevant references and empirical know-hows of experts in blkanking companies. The developed system provides powerful capabilities for process planning and die design of stator and rotor parts.

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Development of Rule-Based Knowledge Representation Supporting Tool for Design Digital Moister System (설계 디지털 마이스터 시스템 구축을 위한 규칙 기반 지식 표현 지원 도구 개발)

  • Nam S.H.;Kang H.W.;Lee W.;Suh H.W.;Choi H.J.
    • Proceedings of the Korean Society of Precision Engineering Conference
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    • 2006.05a
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    • pp.633-634
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    • 2006
  • Recently we started a development of the digital meister expert system for the product design supporting in manufacturing industry. Knowledge representation is of major importance in digital moister expert system. This rule-based expert system-knowledges are designed for a certain type of knowledge representation such as rules or logic. The way in which a rule-based expert system represents knowledge affects the development, efficiency, speed, and maintenance. Eventually, this digital moister system is used to the engineer in manufacturing industry for the process control, production management and system management. In this paper, we propose the digital moister system knowledge representation method for product design supporting in manufacturing industry and we present introduction and contents of rule-based knowledge representation supporting tool.

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The Bad Effect of Mixed Evaluation and the Role of Mathematical Education (혼용평가 폐해와 수학교육의 역할)

  • Moon, Kwon-Bae
    • The Mathematical Education
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    • v.47 no.3
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    • pp.387-398
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    • 2008
  • In this paper, the mathematical knowledges in higher education which are capable of improving the ability of the problem, scientific techniques and creativity are pinpointed as crucial necessary conditions for the development of the Engineering and Natural Science Sections. It is stressed most of all that the mixed evaluation of mathematics in college entrance examination is the main culprit to the crisis of these sections and thus the strengthening of the mathematics education is vital to the section. Also, another role of mathematical education for these sections is introduced.

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A Study on Possibility of Practical Use of Cryptarithmetic Problems in Teaching and Learning of Mathematics (수학 교수.학습에서의 암호산술 문제의 활용 가능성에 관한 연구)

  • 박교식
    • School Mathematics
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    • v.2 no.2
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    • pp.333-355
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    • 2000
  • In this paper, possibility of practical use of cryptarithmetic problems in teaching and learning of mathematics is discussed. There might be seven cases to use them practically like followings: (1) Cryptarithmetic problems might be used for deepening the mathematical knowledges. (2) Cryptarithmetic problems might be used for fostering mathematical thinking abilities. (3) Cryptarithmetic problems might be used for fostering problem solving abilities. (4) Cryptarithmetic problems might be used as open ended problems. (5) Cryptarithmetic problems might be used as materials for personalized learning. (6) Cryptarithmetic problems might be used as materials for cooperative learning. (7) Cryptarithmetic problems might be used as materials for problems posing.

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Expert system for cucumber disease and physiological disorders

  • Cho, Seong-In;Park, Eun-Woo;Bae, Young-Min
    • Proceedings of the Korean Society for Agricultural Machinery Conference
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    • 1996.06c
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    • pp.632-637
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    • 1996
  • An expert system for cucumber disease and nutritional disorders(ESCD) was developed using HCLIPS in which several interface programs were added to CLIPS developed in NASA. The knowledges for constructing knowledge base was obtained from interviews with farmers, agrochemical vendors and employees of agrochemical company. The ESCD is able to diagnose eleven diseases and twelve nutritional disorders which farmers, agrochemical vendors and employees of agrochemical company. The ESCD is able to diagnose eleven diseases and twelve nutritional disorders which could frequently found in fields and greenhouses. Validation of ESCD by twenty -four experts proved a possibility of its practical use for diagnosing cucumber diseases and nutritional disorders in the future.

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