• Journal of Marine Bioscience and Biotechnology
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• v.3 no.1
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• pp.1-6
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• 2008

Angola has a coastline of about 1,650 km long. Two diverging current namely, the Angola current with its warm water from the north and the cold Benguella Current in the south create a strong up-welling with a high productive ecosystem for marine resources. The area from Lobito to the mouth of the Cunene River, also known as the Southern fishing zone is by far the most productive of Angola's fishing zones. In 1977, the total potential of its marine fisheries sector was estimated at more than 700,000 tonnes per annum. In 2003, the Total Allowable Catch (TAC) established for demersal species was 57,600 tonnes and 160,000 tonnes for pelagic species. The most important resources are various marine demersal and pelagic fish including pilchard and the Cape and Cunene horse Mackerel (Tranchurus capensis and T. trecae). Sardinellas (Sardinella aurita and S. maderensis) are fished in parallel with horse mackerel. The rest of the catches are mainly demersal spp. and some deep water crustaceans. The demersal sppecies consist of Hake (Merluccius polli and M. capensis) and the large eye dentex spp. Tunas are caught at certain times of the year whilst some marine shrimp are also harvested from the Angolan waters. Angola also has several high value freshwater fish species, exploited by about 255 fishers. Tilapia sp. is among the most important and abundant fresh water fish found in Angola. Other species include the catfish (Clarias gariepinus) and fresh water prawns (Macrobrachuin rosenbergii). Some aquaculture ponds have been established in the country side, but due to lack of investment, proper training and the impact of civil war have seriously limited developments in the sub sector.

• Journal of Life Science
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• v.12 no.1
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• pp.32-42
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• 2002

It was researched to react horse serum-BChE with hefanoylthiocholine chosen among choline esters. According as number of carbon of acyl group in choline esters was increased, reactivity was decreased but strength of ES complex was increased (Km=0,140mM). The pH-V/K profile for BChE-catalyzed hydrolysis of hexanoylthiocholine yields a p $K_{a}$ =4.974$\pm$0.028. This value is equal to recent literature that shows systematic shift from dependence of activity on the basic form fo a residue that huts a p $K_{a}$ =6.2~6.4 to catalysis by a residue or residues that has a p $K_{a}$ =4.7~5.0. The resulting kinetic solvent isotope effect of hexanoylthiocholine is $^{D/V}$K=1.18. The magnitude of the isotope effect suggests that proton transfer is not an element of transition-state stabilization.n.

• Korean Journal of Clinical Laboratory Science
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• v.41 no.2
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• pp.83-92
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• 2009

This study was undertaken to examine the effect of oxidants on membrane transport function in renal epithelial cells. Hydrogen peroxide ($H_2O_2$) was used as a model oxidant and the membrane transport function was evaluated by measuring $Na^+$-dependent phosphate ($Na^+$-Pi) uptake in opossum kidney (OK) cells. $H_2O_2$ inhibited $Na^+$-Pi uptake in a dose-dependent manner. The oxidant also caused loss of cell viability in a dose-dependent fashion. However, the extent of inhibition of the uptake was larger than that in cell viability. $H_2O_2$ inhibited $Na^+$-dependent uptake without any effect on $Na^+$-independent uptake. $H_2O_2$-induced inhibition of $Na^+$-Pi uptake was prevented completely by catalase, dimethylthiourea, and deferoxamine, suggesting involvement of hydroxyl radical generated by an iron-dependent mechanism. In contrast, antioxidants Trolox, N,N'-diphenyl-p-phenylenediamine, and butylated hydroxyanisole did not affect the $H_2O_2$ inhibition. Kinetic analysis indicated that $H_2O_2$ decreased Vmax of $Na^+$-Pi uptake with no change in the Km value. Phosphonoformic acid binding assay did not show any difference between control and $H_2O_2$-treated cells. $H_2O_2$ also did not cause degradation of $Na^+$-Pi transporter protein. Reduction in $Na^+$-Pi uptake by $H_2O_2$ was associated with ATP depletion and direct inhibition of $Na^+$-$K^+$-ATPase activity. These results indicate that the effect of $H_2O_2$ on membrane transport function in OK cells is associated with reduction in functional $Na^+$-pump activity. In addition, the inhibitory effect of $H_2O_2$ was not associated with lipid peroxidation.

• Proceedings of the Korea Water Resources Association Conference
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• 2015.05a
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• pp.102-102
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• 2015

최근 중소규모 하천은 하천수 및 하천변 지하수 이용의 증가와 토지이용변화 등 유역 내 수문인자의 특성 변화로 인해 하천의 건천화가 점증하고 있어 하천 환경이 악화되고 있는 실정이다. 본 연구에서는 격자기반의 분포형 장기수문 모델(PGA-CC)을 이용하여 과거 수십년동안 토지이용변화에 따른 하천 건천화 영향을 평가하였다. 실제 건천화가 진행되고 있는 삽교천 상류유역($358.8km^2$)을 선정하였고 토지이용변화분석을 위해 과거 1975년 토지이용도(Past), 현재 2008년 토지이용도(Present)를 구축하였다. 각각의 토지이용 항목 중 변화율이 가장 높은 도시비율은 과거 토지이용도에서는 2.6 %였으며 현재 토지이용도에서는 11.3 %로 8.7 %가 증가하였다. 모델 검보정은 최근 7년(2005-2011)동안 최종유역출구지점에서 유출 검보정을 실시하였다. 그 결과 NSE (Nash-Sutcliffe model efficiency)은 평균 0.71로 유출량의 모의값과 실측값이 유효한 것으로 나타났다. 건천화를 평가하기 위해 시험유역에서의 5 WPs (Watching Points)를 선정하여 과거 및 현재 토지이용조건을 모의하고 유황분석을 통한 갈수 변화량 분석을 실시하였다. 건천화 빈도분석을 위해 GEV (Generalized Extreme Value) 갈수빈도분석을 실시하여 과거 토지이용 모의결과 산정된 평균 갈수량($m^3/s$) 이하로 낮아지는 유출량 일수를 계산하였다. 최종유역출구에서 과거 및 현재 토지이용도에서 모의된 평균갈수량은 각각 $3.27m^3/s$ 및 $3.11m^3/s$로 나타났다. GEV 갈수빈도분석결과 과거 토지이용조건에서의 평균갈수량은 $3.20m^3/s$(재현기간 2.33년)으로 나타났다. 도시증가에 따른 인구증가는 지하수 사용량에 증가를 가져온다. 이는, 건천화에 영향을 미치며 본 연구에서는 지하수이용량 자료(1998-2011)를 이용하여 도시면적과 지하수이용량의 선형회귀분석을 실시하여 과거 22년 지하수 사용량을 예측하였다. 그 결과 지하수사용량 증가는 토지이용변화와 복합적으로 상류유역에 하천의 변화를 가속시키는 것으로 나타냈다.

• Safety and Health at Work
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• v.10 no.2
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• pp.219-223
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• 2019

Background: Ice cooling vests can cause tissue damage and have no flexibility. Therefore, these two undesirable properties of ice cooling vest were optimized, and the present study was aimed to compare the impact of the optimized ice cooling vest and a commercial paraffin cooling vest on physiological and perceptual strain under controlled conditions. Methods: For optimizing, hydrogel was used to increase the flexibility and a layer of the ethylene vinyl acetate foam was placed into the inside layer of packs to prevent tissue damage. Then, 15 men with an optimized ice cooling vest, with a commercial paraffin cooling vest, and without a cooling vest performed tests including exercise on a treadmill (speed of 2.8 km/hr and slope of %0) under hot ($40^{\circ}C$) and dry (40 %) condition for 60 min. The physiological strain index and skin temperature were measured every 5 and 15 minutes, respectively. The heat strain score index and perceptual strain index were also assessed every 15 minutes. Results: The mean values of the physiological and perceptual indices differed significantly between exercise with and without cooling vests (P < 0.05). However, the difference of the mean values of the indices except the value of the skin temperature during the exercises with the commercial paraffin cooling vest and the optimized ice cooling vest was not significant (P > 0.05). Conclusions: The optimized ice cooling vest was as effective as the commercial paraffin cooling vest to control the thermal strain. However, ice has a greater latent heat and less production cost.

• Wind and Structures
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• v.29 no.3
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• pp.163-175
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• 2019

Multispan suspension bridges make a good alternative to single-span ones if the crossed strait or river width exceeds 2-3 km. However, multispan three-tower suspension bridges are found to be very sensitive to the wind load due to the lack of effective longitudinal constraint at their central tower. Moreover, at certain critical wind speed values, the aerostatic instability with sharply deteriorating dynamic characteristics may occur with catastrophic consequences. An attempt of an in-depth study on the aerostatic stability mode and damage mechanism of three-tower suspension bridges is made in this paper based on the assessment of strain energy and dynamic characteristics of three particular three-tower suspension bridges in China under different wind speeds and their further integration into the aerostatic stability analysis. The results obtained on the three bridges under study strongly suggest that their aerostatic instability mode is controlled by the coupled action of the anti-symmetric torsion and vertical bending of the two main-spans' deck, together with the longitudinal bending of the towers, which can be regarded as the first-order torsion vibration mode coupled with the first-order vertical bending vibration mode. The growth rates of the torsional and vertical bending strain energy of the deck after the aerostatic instability are higher than those of the lateral bending. The bending and torsion frequencies decrease rapidly when the wind speed approaches the critical value, while the frequencies of the anti-symmetric vibration modes drop more sharply than those of the symmetric ones. The obtained dependences between the critical wind speed, strain energy, and dynamic characteristics of the bridge components under the aerostatic instability modes are considered instrumental in strength and integrity calculation of three-tower suspension bridges.

• Journal of the Korean Society of Environmental Restoration Technology
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• v.22 no.1
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• pp.33-45
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• 2019

Compound disaster is the type that increases the impact affected by two or more hazard events, and attention to compound disaster and multi-hazards risk is growing due to potential damages which are difficult to predict. The objective of this study is to analyze the possible impacts of post-fire landslide scenario quantitatively by using TRIGRS (Transient Rainfall Infiltration and Grid-Based Regional Slope-Stability Analysis), a physics-based landslide model. In the case of wildfire, soil organic material and density are altered, and saturated hydraulic conductivity decrease because of soil exposed to high temperature. We have included the change of soil saturated hydraulic conductivity into the TRIGRS model through literature review. For a case study, we selected the area of $8km^2$ in Pyeongchang County. The landslide modeling process was calibrated before simulate the post-wildfire impact based on landslide inventory data to reduce uncertainty. As a result, the mean of the total factor of safety values in the case of landslide was 2.641 when rainfall duration is 1 hour with rainfall intensity of 100mm per day, while the mean value for the case of post-wildfire landslide was lower to 2.579, showing potential landslide occurrence areas appear more quickly in the compound disaster scenario. This study can be used to prevent potential losses caused by the compound disaster such as post-wildfire debris flow or landslides.

• Journal of Physiology & Pathology in Korean Medicine
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• v.36 no.3
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• pp.94-99
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• 2022

The discovery of biomarkers related to pattern identification (PI), the core diagnostic theory of Korean medicine (KM), is one of the methods that can provide objective and reliable evidence by applying PI to clinical practice. In this study, 40 diabetic patients and 41 healthy control subjects recruited from the Korean medicine clinic were examined to determine the human electrical response related to the deficiency pattern, a representative pattern of diabetes. Qi-Blood-Yin-Yang deficiency pattern scores, which are representative deficiency patterns for diabetes mellitus, were obtained through a questionnaire with verified reliability and validity, and the human electrical response was measured non-invasively using a bioimpedance meter. In ANCOVA analysis using gender as a covariate, the 5 kHz frequency resistance and 5-250 kHz frequency reactance were significantly lower in the diabetic group than in non-diabetic control group. In addition, the multiple regression analysis showed a positive correlation (R2=0.11~0.19) between the Yang deficiency pattern score and resistance value for the diabetic group; the correlation was higher at higher frequencies of 50kHz (R2=0.18) and 250kHz (R2=0.19) compared to 5kHz(R2=0.11). In contrast, there was no such significant association in the control group. It implies that bioimpedance resistance measured at finite frequencies may be useful in predicting Yang deficiency, which is closely related to diabetic complications by reflecting the decrease in body water content and metabolism. In the future, large-scale planned clinical studies will be needed to identify biomarkers associated with different types of PI in diabetes.

• Journal of Radiation Protection and Research
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• v.46 no.2
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• pp.58-65
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• 2021

Background: The evaluation of skyshine distribution, release of airborne radioactive nuclides, and soil activation and groundwater migration were required for radiological assessment of the impact on the environment surrounding In-Flight (IF)-system facility of the RAON (Rare isotope Accelerator complex for ON-line experiment) accelerator complex. Materials and Methods: Monte Carlo simulation by MCNPX code was used for evaluation of skyshine and activation analysis for air and soil. The concentration model was applied in the estimation of the groundwater migration of radionuclides in soil. Results and Discussion: The skyshine dose rates at 1 km from the facility were evaluated as 1.62 × 10^-3 μSv·hr^-1. The annual releases of ³H and ¹⁴C were calculated as 9.62 × 10^-5 mg and 1.19 × 10^-1 mg, respectively. The concentrations of ³H and ²²Na in drinking water were estimated as 1.22 × 10^-1 Bq·cm^-3 and 8.25 × 10^-3 Bq·cm^-3, respectively. Conclusion: Radiological assessment of environmental impact on the IF-facility of RAON was performed through evaluation of skyshine dose distribution, evaluation of annual emission of long-lived radionuclides in the air and estimation of soil activation and groundwater migration of radionuclides. As a result, much lower exposure than the limit value for the public, 1 mSv·yr^-1, is expected during operation of the IF-facility.

• Advances in Computational Design
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• v.8 no.1
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• pp.13-36
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• 2023

The Puebla-Morelos Earthquake (Mw 7.1) occurred in Mexico in 2017 causing 44 buildings to collapse in Mexico City. This work evaluates the non-linear response of a 6-story reinforced concrete (RC) frame prototype model with masonry infill walls on upper floors. The prototype model was designed using provisions prescribed before 1985 and was subjected to seismic excitations recorded during the earthquakes of 1985 and 2017 in different places in Mexico City. The building response was assessed through a damage index (DI) that considers low-cycle fatigue of the steel reinforcement in columns of the first floor, where the steel was modeled including buckling as was observed in cases after the 2017 earthquake. Isocurves were generated with 72 seismic records in Mexico City representing the level of iso-demand on the structure. These isocurves were compared with the location of 16 collapsed (first-floor column failure) building cases consistent with the prototype model. The isocurves for a value greater than 1 demarcate the location where fatigue failure was expected, which is consistent with the location of 2 of the 16 cases studied. However, a slight increase in axial load (5%) or decrease in column cross-section (5%) had a significant detrimental effect on the cumulated damage, increasing the intensity of the isocurves and achieving congruence with 9 of the 16 cases, and having the other 7 cases less than 2 km away. Including column special detailing (tight stirrup spacing and confined concrete) was the variable with the greatest impact to control the cumulated damage, which was consistent with the absence of severe damage in buildings built in the 70s and 80s.