• Title/Summary/Keyword: Km value

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A Study on The Change Characteristic of Basin Topographical Parameters According to the Threshold Area of Stream Creation (하천생성 임계면적의 변화에 따른 유역의 지형관련 매개변수들의 특성분석)

  • Ahn, Seung-Seop;Lee, Jeung-Seok;Kim, Jong-Ho;Lim, Kee-Seok
    • Journal of the Korean Association of Geographic Information Studies
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    • v.8 no.2
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    • pp.10-20
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    • 2005
  • The change of stream creation has a very sensitive effect on runoff analysis model using the divergence characteristic of stream. Therefore, in this study, the threshold area of stream creation was examined the change characteristic of topographical parameters. The subject basin of the research was the upper basin of the Kumho water gage station which is located in the middle of the Kumho river. The 1:25,000 numerical geography which was constructed $10{\times}10m$ mesh was used. The range of investigation of topographical parameters are number of stream order, length, area, slope, basin relief, sinuosity ratio, drainage density and total stream length etc. It was found from the result of analysis that the threshold value of 1st order stream has a very big effect on topographical parameters of basin. It was found that the threshold area of stream creation was under $0.10km^2$, the parameters showed a big change but showed a very small change over $0.10km^2$.

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Effect of Colored Potato Flakes Against Acetaminophen-induced Liver Damage in Rats

  • Ohba, Kiyoshi;Watanabe, Shoko;Han, Kyu-Ho;Hashimoto, Naoto;Noda, Takahiro;Shimada, Ken-Ichiro;Tanaka, Hisashi;Sekikawa, Mitsuo;Fukushima, Michihiro
    • Food Science and Biotechnology
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    • v.16 no.3
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    • pp.463-469
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    • 2007
  • We examined the hepatoprotective effects of colored potato flakes on acetaminophen (AAP)-induced liver damage in rats. F344/DuCrj (8 week-old) rats were fed a cholesterol-free diet with 54.9486 g of ${\alpha}$-corn starch/100g diet and were orally treated with 25% colored flakes of Kitamurasaki (KM: light purple), Northern Ruby (NR: red), and Shadow Queen (SQ: medium purple) potatoes co-administered with AAP (0.5 g/100 g diet) for 4 weeks. The hepatic thiobarbituric acid-reactive substances (TBARS) values in the KM, NR, and SQ groups were significantly lower (p<0.05) than those in the control groups with and without AAP. Furthermore, the hepatic catalase, Mn-superoxide dismutase (SOD), and Cu/Zn-SOD mRNA levels in the KM, NR, and SQ groups were higher than those in the control groups with and without AAP. The present findings suggest that colored potato flakes are useful as a prophylactic agent against oxidative liver damage.

Establishment of Knowledge Management Strategies for Small and Medium-sized General and Special Construction Companies (중소${\cdot}$전문건설업체를 위한 지식경영 전략 수립)

  • Lee Tai-Sik;Lee Dong-Wook;Park Se-Jin
    • Proceedings of the Korean Institute Of Construction Engineering and Management
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    • autumn
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    • pp.602-605
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    • 2003
  • Interests in knowledge asset as a way of improving the values of companies and as a survival strategy have increased worldwide. In Korea, since the mid 1990s, many construction companies have realized the importance of knowledge and large companies have been forerunners in adopting KM. However, unlike large companies that readily adopt knowledge management, small & medium-sized general and special construction companies lack understanding of knowledge management and have hard time keeping updated with the current information and the state-of-art information technologies due to financial and organizational reasons. This research presents knowledge management strategies, which involves knowledge management adoption plans appropriate for small & medium-sized general and special construction companies as a way of increasing the value and competitive power of the companies.

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Studies on Naringinase Produced from Aspergillus nidulans (Part 4) Immobilization of Naringinase on DEAE-Sephadex A-25 (Aspergillus nidulans가 생산하는 Naringinase에 관한 연구 (제4보) DEAE-Sephadex A-25에 의한 Naringinase의 고정화)

  • 송충석;변유량;유주현
    • Microbiology and Biotechnology Letters
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    • v.7 no.3
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    • pp.141-147
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    • 1979
  • Naringinase from Atpergillus nidulans was immobillized on DEAE-Sephadex A-25 and its characteristics were studied. The optimal conditions for the preparation of the immobilized enzyme were as follow; optimal pH, incubation time and the suitable amount of enzyme were 6.0, 30 min. and 110 units per gram of the dried ion exchage resin, respectively. The optimal pH of the immobilized enzyme was higher than that of the native enzyme. The optimal temperature increased from 4$0^{\circ}C$ to 5$0^{\circ}C$. The heat and pH stability of the immobillized enzyme were better than those of the native enzyme. No significant difference in the Michaelis constant was detected. Activation energy of the immobilized enzyme was 7.96 Kcal/mole, and the apparent Michaelis rate equation was used to describe the action of this material. The degree of hydrolysis was dependant on the flow rate at low rate of perfusion through the column. As the flow rate increased, the value of the apparent Km decreased.

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Effects of Lead Acetate on the Uptake of [$^3$H]-serotonin by the Synaptosomes Separated from the Cerebrum and Brain Stem of the Rat (초산납이 흰쥐 synaptosome의 [$^3$H]-serotonin의 흡수에 미치는 영향)

  • 이규석;박순철
    • Korean Journal of Environmental Biology
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    • v.18 no.2
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    • pp.255-262
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    • 2000
  • This study was carried out to investigate the physiological changes induced acutely with the low doses of lead acetate in the synaptosomes from the cerebrum and brain stem of the rat. The general uptake patterns of [$^3$H]-serotonin were observed in synaptosomes, as a model of presynaptic nerve terminal, from the cerebrum and brain stem. And the effects of the low doses of lead acetate on the uptake process were investigated id vitro and in vivo. The Km value of the uptake of the [$^3$H]-serotonin by the synaptosomes was 0.5 $\mu$M in the cerebrum and 0.1 $\mu$M in the brain stem. These low values reveal that the synaptosomes from the cerebrum and the brain stem have a high affinity to [$^3$H]-serotonin, especially in brain stem. The uptake of $\mu$M-serotonin was dependant on the sodium and potassium ions. When being treated with ouabain, the $Na^+$ $-K^+$ ATPase inhibitor, the uptake of [$^3$H]-serotonin was reduced. This supports strongly that the uptake of [$^3$H]-serotonin was sensitive to the changes of the concentrations of the sodium and potassium ions. When the calcium channel blocker, verapamil, was treated, the uptake of [$^3$H]-serotonin was changed only in synaptosomes from the brain stem. The uptake of [$^3$H]-serotonin was reduced by the lead treatment in the synaptosomes from the cerebrum and brain stem in vitro and in vivo. [lead acetate, synaptosomes, $^3$H-serotonin, rat]

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Characteristics of Fog and Mist Observed in the Rural Area of Chongju and Chongwon (청주-청원 지역에서 관측한 안개와 박무의 특성 연구)

  • 윤마병;정용승
    • Journal of Korean Society for Atmospheric Environment
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    • v.12 no.1
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    • pp.15-21
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    • 1996
  • Daily measutements of visibility on 09 LST have been made at a rural site in Chong-won, Chong-book since 1991 to find out a possible influence of emissions of anthropogenic pollutants and water vapout in urban and rural environments. Daily visibility data collected over four-year period were compared with the available visibility and air quality data obtainde from other stations. Detailed examinations of our data showed that the frequency of fog occurrence (visibility .leq. 1 km) at a rural site (KNUE) was at least three times higher (77 days per year) than the frequency of fog both in Chong-ju city (19 days) and at the Air Force Base(AFB) in the rural area. We interpret that the higher frequency of fog at KNUE was due to abundant water vapour in the Mieho River (upstream of the Keum River) area. In Chong-ju city, fog usually continued for a relatively long duration, while it dissipated simewhat faster in the rural environment due to higher solar radiation in the countryside area. The number of misty (.leg. 6 km) days (including foggy days) at KNUE were 235 days as compared with 135 days at the AFB and 67 days in Chong-ju city. In turn the number of days with low visibility (less than 6 km) at KNUE was about 64% per year. Since the moisture alone in a calm morning does not produce a visibility impairment, there must had abundant condensation nuclei including anthropogenic air pollutants. Air pollution was examined, for instance, average values of TSP for November and December 1993 were 115 and 116.mu.g/m$^{3}$, respectively. We conclude that the above mentioned environmental conditions with moisture are favourable for the formation of fog and mist in the rural sampling site at KNUE. Additionally, we found at least 10 days of acid fog at KNUE in September 1994 alone. Measured pH values in the acid for water were in the range of 4.36 .sim. 5.01 with the mean value of 4.51 Our observations suggested that strikingly acid fog do occur occasionally even in the rural environment.

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Studies on the Characterization of Cellulase Produced by Trichoderma viride QM 9414 (Trichoderma viride QM 9414가 생산하는 Cellulase 특성에 관한 연구)

  • 윤은숙;이혜정
    • The Korean Journal of Food And Nutrition
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    • v.3 no.1
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    • pp.57-68
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    • 1990
  • In order to obtain the fundamental informations on cellulase of Trichoderma viride QM 9414 for its production and utilization, some physico-chemical properties of the enzyme were reviewed. When T. viride QM 9414 was cultured on wheat bran medium, filter paper-disintegrating and carboxymethyl cellulose-saccharifying activity were increased with the cell growth, and thereafter CMC-saccharifying activity was kept on almost the same leved while filter-paper disintegrating activity was decreased sharply. And B-glucosidase was formed maximally on the late stationary phase of growth. The crude cellulase of cell-free extracts was purified by (NH4)2SO4 fractionation, Sephadex-G 200 column chromatography and DEAE Sephadex A-50 column chromatography. Filter paper-disintegrating, CMC-saccharifying and B-glucosidase activity were purified 10-fold, 47-fold and 38-fold, respectively. The crude enzyme was proved to be a complex of three different enzyme proteins which were showing filter paper-disintegrating, CMC-saccharifying and B-glucosidase activity. The optimal pH of the three enzyme components was alike pH 4.0, and the optimal temperature for CMC-saccharifying, filter paper-disintegrating and B-glucosidase activity were 4$0^{\circ}C$, 45$^{\circ}C$ and 5$0^{\circ}C$ respectively. The Km and Vmax values of CMC saccharifying activity for CMC were 0.485% and 3.10, and the Km and Vmax vallues of B-glucosidase for PNPG were 0.944$\times$10-3M and 0.097, respectively. The Km and Vmax values of filter paper-disintegrating activity for Avicel were determined to be 0.09% and 0.178, respectively. B-Glucosidase activity was competitively inhibited by glucose, and the Ki value for this enzyme was 3.54$\times$10-3M, CMC saccharifying activity was found to be greatly inhibited by cellobiose.

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Total bilirubin level as a biomarker for dampness-heat differentiation in traditional Korean treatment for jaundice

  • Sohn, Ki Cheul;Jung, Hyun-Jung;Lee, A-Jin;Kim, Sang-Gyung;Shin, ImHee;Kwak, Sang Gyu
    • The Journal of Korean Medicine
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    • v.34 no.4
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    • pp.46-55
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    • 2013
  • Objectives: Classifying the pattern of jaundice during diagnosis will significantly improve the outcome of common KM interventions. This study aimed at determining an objective index for accurately diagnosing heat and dampness KM patterns in patients with jaundice. Methods: We systematically reviewed laboratory findings from case reports published in the scientific literature of Korean medicine. Cases were classified as following either the heat or dampness pattern. Biochemical indices were compared using a Bayesian factor (BF) analysis and standard t-tests. Results: The laboratory findings of 32 patients were evaluated. The heat pattern was observed in 17 patients and the dampness pattern in 15. No significant differences were observed between the 2 groups in terms of white blood cell count (BF=1.659); hemoglobin concentration (BF=2.627); platelet count (BF=1.019); or levels of direct bilirubin (BF=1.453), aspartate aminotransferase (BF=1.226), alanine aminotransferase (BF=1.340), alkaline phosphatase (BF=2.344), or gamma-glutamyl transpeptidase (BF=2.782). However, total bilirubin levels were significantly higher in the dampness pattern group (BF=0.854, P-value=0.070). Conclusions: Patients with high total bilirubin levels may predominantly follow the dampness pattern, while those with low levels may predominantly follow the heat pattern. These results are expected to be useful for the development of timely and efficient KM treatments as well as new integrative therapeutic approaches for jaundice. However, further studies are essential to fully validate the utility of total bilirubin as a biomarker for differentiating between heat and dampness patterns.

A Study on the Reduced Spatial Extent of DMZ (DMZ의 축소된 공간 범위에 대한 연구)

  • Jung, Kyu-Surk;Shin, Hyun-Tak;Kim, Sang-Jun;An, Jong-Bin;Yoon, Jung-Won;Kwon, Yeong-Han;Heo, Tae-Im
    • Journal of the Korean association of regional geographers
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    • v.21 no.2
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    • pp.355-363
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    • 2015
  • DMZ(Demilitarized Zone) created as part of the Armistice Agreement is important zone in the way that historic and eco-cultural value as well as military and political image of this are remarkable. Furthermore, the concern of DMZ has been rising at home and abroad. Even though various studies on this subject have been constantly spurring according to the significance, the practical researches on spatial range of DMZ are very weak. The Purpose of this research is to show the factual spatial extent of DMZ from the mouth of the Imjingang River in the west to the town of Goseong in the east. This study proved the area of corresponding DMZ is approximately $570km^2$ contrary to the previous studies and claims it is difficult to measure the actual length of MDL(Military Demarcation Line) regarded as 155mile in this situation of Korea peninsula.

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Propagation characteristics of CMEs associated magnetic clouds and ejecta

  • Kim, Roksoon;Gopalswamy, Nat;Cho, Kyungsuk;Moon, Yongjae;Yashiro, Seiji;Park, Youngdeuk
    • The Bulletin of The Korean Astronomical Society
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    • v.37 no.2
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    • pp.132.2-132.2
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    • 2012
  • We have investigated the characteristics of magnetic cloud (MC) and ejecta (EJ) associated coronal mass ejections (CMEs) based on the assumption that all CMEs have a flux rope structure. For this, we used 54 CMEs and their interplanetary counter parts (interplanetary CMEs: ICMEs) that constitute the list of events used by the NASA/LWS Coordinated Data Analysis Workshop (CDAW) on CME flux ropes. We considered the location, angular width, and speed as well as the direction parameter, D. The direction parameter quantifies the degree of asymmetry of the CME shape, and shows how closely the CME propagation is directed to Earth. For the 54 CDAW events, we found several properties of the CMEs as follows: (1) the average value of D for the 23 MCs (0.62) is larger than that for the 31 EJs (0.49), which indicates that the MC-associated CMEs propagate more directly to the Earth than the EJ-associated CMEs; (2) comparison between the direction parameter and the source location shows that the majority of the MC-associated CMEs are ejected along the radial direction, while many of the EJ-associated CMEs are ejected non-radially; (3) the mean speed of MC-associated CMEs (946 km/s) is faster than that of EJ-associated CMEs (771 km/s). For seven very fast CMEs (>1500 km/s), all CMEs with large D (>0.4) are associated with MCs and the CMEs with small D are associated with EJs. From the statistical analysis of CME parameters, we found the superiority of the direction parameter. Based on these results, we suggest that the CME trajectory essentially decides the observed ICME structure.

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