• The Journal of Korean Medical History
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• v.34 no.1
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• pp.75-82
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• 2021

Through articles published in the 『Seungjeongwon Ilgi』, the following conclusions were obtained by analyzing how the Joseon royal family used Asi-acupoint therapy. Various Asi-acupoints were used in the Joseon royal family to treat diseases; King Sukjong was the king who was treated the most with Asi-acupoint therapy, followed by King Yeongjo, King Hyeonjong, King Hyojong and King Injo. The body parts with the most Asi-acupoint therapy are lower extremities, followed by interbody, upper extremities, other parts, and head. Asi-acupoint therapy was treated evenly throughout the body. The most common disease using Asi-acupoint therapy is pain, followed by abscesses, other symptom, internal damage, and external infections. When Asi-accupoint was executed, the ratio of acupunture and moxiubustion was 65:35, indicating that acupuncture was somewhat frequently used.

• Journal of Korean Medical classics
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• v.27 no.4
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• pp.55-72
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• 2014

Objectives : King Hyojong (1619-1659) was the 17th king of the Joseon Dynasty. He was on the throne from 1649 to 1659. The king was a center of state rule in ancient times. This meant that the physical and mental status of a king was very confidential information. In the royal court of Joseon Korea, the treatment process for the king had to be performed under the surveillance of close associates, and this whole process had to be recorded by the official secretary. This is the reason that I referred to the Daily Records of Royal Secretariat of Joseon Dynasty. Methods : Relevant articles were extracted from Daily Records of Royal Secretariat of Joseon Dynasty and analyzed according to the main arguments of this paper. Some other related sources were referred in terms of King Hyojong's ailments and treatments. Results & Conclusions : King Hyojong suffered from various diseases during his time on the throne. Fever was the most frequent ailment; he also often had diarrhea followed by poor appetite. I assume that he must have suffered from diabetes considering his ailments. Additionally, his final treatment records clearly show that his ailments were similar to diabetic complications.

• Journal of the Korean Society of Clothing and Textiles
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• v.39 no.1
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• pp.133-146
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• 2015

King and Crown Prince's Gwanbok (冠服) written in "Goryeosa" Yeobokji was the bestowment of robes and crowns by the Son of Heaven who yielded hegemony over East Asia. It designated the King and Crown Prince of Goryeo as real and authentic as well as confirmed the political status of Goryeo in East Asia. In "Goryeosa" Yeobokji, the King's Gwanbok is of higher stature than the adornments of the King's ritual robes (祭服) and court robes (朝服) which held a domestic political significance. In East Asia, bestowment of voiture (車) and robe (服) usually appeared in the multistate system. In the $10^{th}$ century, the Later Jin (後晋) spread the idea of investiture and bestowment to Khitan (契丹). The Liao (遼) or Khitan and the Jin (金), the Conquest Dynasties, endeavored to establish the legitimacy of the Son of Heaven by imitating Sinocentrism by means of investiture and bestowment. In the reign of XingZong (興宗) and DaoZong (道宗) of Liao, the ritual of investiture and bestowment for Goryeo was in the making, adding titles and bestowments in the occasion of the elevation of Emperor Liao's honorific title. King Munjong (文宗) of Goryeo reached 9-bestowment which symbolized the first of the feudal lords in East Asia. This exceptional respect for Goryeo went on to Jin's investiture and bestowment. From then, 9-bestowment was defined as an international decorum (禮) toward Goryeo. This historical study of Gwanbok (冠服) of "Goryeosa", indicates: First, the King's Ceremonial Robe with Nine-symbol Design were designated from the early to middle of the Goryeo Dynasty by investiture and bestowment from the Conquest Dynasties. Second, the bestowed King's Robe and Crown had simultaneous functions for domestic order and international order. Goryeo did not follow ideological Sinocentrism but followed practical interest by accepting Confucian Li (禮) philosophy passed on through the Conquest Dynasties.

• Asian Pacific Journal of Cancer Prevention
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• v.16 no.3
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• pp.1247-1250
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• 2015

Background: Psoriasis, a common cutaneous disorder characterized by inflammation and abnormal epidermal proliferation with a prevalence of 2-3% in the general population, may be linked to certain types of cancer. Several studies have reported an association between interleukin 10 (IL-10) variant polymorphisms and inflammatory diseases such as psoriasis vulgaris although the results vary according to the population studied. No studies have been performed in the Saudi population. The present study concerned novel variants and other genetic polymorphisms of the promoter and exonic regions of the IL10 gene in patients with moderate to severe psoriasis and potential differences in genotype compared to a group of healthy volunteers. Materials and Methods: Patients with moderate to severe psoriasis and healthy controls with no personal or family history of psoriasis were selected from the central region of Saudi Arabia. Polymorphisms of the IL 10 gene of both groups were genotyped. Results: We observed two novel variants in 5'UTR region of the promoter precursor with higher prevalence of the genotype with both wild-type alleles in patients compared to the healthy control group. The differences at positions -377 and -150 were significantly associated with disease, both the variants conferred strong protection against psoriasis in Saudi patients. Conclusions: This observation provides further support for the importance of the part that IL10 plays in the pathophysiology of this disease. Confirmation of our findings in larger populations of different ethnicities would provide evidence for the role of IL-10 in psoriasis.

• Journal of the East Asian Society of Dietary Life
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• v.20 no.6
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• pp.932-938
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• 2010

This study was performed to determine the proximate analysis of Pleurouts eryngii and quality characterisitcs of pork cutlet sauce with added king oyster mushroom (Pleurotus eryngii). Pork cutlet sauce was prepared with different levels of king oyster mushroom powder (0, 1, 3, 5, and 7%) and stored for 21days at $25^{\circ}C$. Antioxidant activity was significantly increased by addition of king oyster mushroom powder (p<0.001). L, a and b value ignificantly increased with the increased of king oyster mushroom powder concentration. As king oyster mushroom powder concentration increased, pH value was increased and titratable acidity (%) value was decreased. pH value and titratable acidity (%) value were stable during storage period. Viscosity value and $Brix^{\circ}$ were significantly increased by addition of king oyster mushroom powder (p<0.001). The overall acceptability, sweetness and taste of the pork cutlet sauces with added 5% king oyster mushroom powder attained high scores.

• Journal of architectural history
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• v.20 no.6
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• pp.131-146
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• 2011

The purpose of this study is to understand the architectural space of Chimjeon (寢殿), the King's Bedroom, and Backyard, in the early Joseon Dynasty. The Royal palace can be divided into three parts, political space for King, living space for King and his family and government office. So first, we should to understand the characteristics of each space in the Royal Palace. Up to now we have looked at the architectural space of the King's Bedroom in the central area and Backyard in Gyeongbokgung (景福宮), one of the Royal Palace, the result of this study is as followings. Cheonchujeon (千秋殿) and Manchunjeon (萬春殿) were not both sides of Sajeongjeon (思政殿), were on the north side of Gangnyeongjeon (康寧殿) Gangnyeongjeon was not a bedroom for the King and Queen, only for King. Bedroom for Queen was located another space in the Royal palace. There was Hamwonjeon on the west side of Koytaejeon. Jamidang and Cheongyeonroo were on the right side of Koytaejeon The Backyard on the north side of Gyeongbokgung had a wide area for horseback archery and the practice of battle formation The arrangement of the King's bedroom in the central area was assumed like as the Fig 7. and Fig 8.

• Journal of architectural history
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• v.29 no.3
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• pp.67-78
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• 2020

This study examines the transitional situation that can be seen from the palace operation in early Joseon Dynasty. The first decades of Joseon after the nation was founded differ from the Joseon Dynasty as a whole, but rather similar with the Goryeo Dynasty. By examining "The History of Goryeo(高麗史)," it showed that palace operation during the Goryeo Dynasy was marked by the fact that a separate palace was built and resided in despite the existence of the Bongweol(本闕, main palace) as the central palace. The separation of the parent's generation and the children's generation was shown through the establishment of one's own palace. Such trait of Goryeo affected palace construction directly after the founding of Joseon. This can be shown from the characteristic of palace operation by generation. The construction of the Changdeokgung Palace(昌德宮) of King Taejong, as his own palace, is an example. Afterwards, the palace system of Joseon was established, and the space of the king and the crown prince was merged through ritual reform during the reign of King Sejong. However, the space for the parents of the king were considered separate, and this influence continued to the reign of King Seongjong. The construction of Changgyeonggung Palace(昌慶宮) during the reign of King Seongjong is an event where the king proclaimed the separation with his mother and grandmother.

• Asian Pacific Journal of Cancer Prevention
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• v.14 no.1
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• pp.81-85
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• 2013

Background: Early diagnosis of carcinoma of bladder remains a challenge. Survivin, a member of the inhibitor of apoptosis (IAP) protein family, is frequently activated in bladder carcinoma. The objective of this study was to investigate urinary survivin as a marker for diagnosis of urinary bladder. Materials and Methods: We examined urinary survivin concentration in 28 healthy individuals, 46 positive controls and 117 cases of histologically proven TCC prior to transurethral resection, using ELISA, and compared values with findings for urinary cytology. Results: Survivin was found to be significantly higher in the cancer group (P<0.05). A cut off value of 17.7 pg/ml was proposed, with an approximate sensitivity of 82.9% and specificity of 81.1% (P<0.0001), whereas urine cytology had a sensitivity of 66.7% and a specificity of 96.0%. Conclusions: Urinary survivin can be used as a non-invasive diagnostic biomarker for TCC bladder, both for primary and recurrent disease.

• Asian-Australasian Journal of Animal Sciences
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• v.15 no.7
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• pp.982-985
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• 2002

A study was carried out to determine glucose kinetics, nutrient balance and milk production of lactating Etawah crossbred goats. The animals (27.2 to 29.1 kg BW) were randomly divided into four levels of dietary treatment groups: the first group R1 received 100% (3 kg) fresh king grass (Penisetum purpuroides), the second group R2 received 75% king grass and 25% king grass silage prepared with chicken manure, the third group R3 received 50% king grass and 50% silage, and the fourth group R4 received 100% silage. In addition to the roughage, each group received 800 g of concentrate (CP 14.77% of DM; 17.26 MJ/kg). Animals fed king grass silage made with chicken manure were found to be superior to the group fed king grass alone. Glucose kinetics and retained energy were significantly affected. Calculations showed that glucose requirements for maintenance and milk production can be met for the groups with high levels of silage (R3 and R4). The values of glucose flux were in the range of 2.52 to 4.50 mg/min.kg $BW^{0.807}$ which are lower, but close to, the values for the temperate lactating dairy cow. The present glucose flux value for the lactating Etawah crossbred goat is higher than the previous value published from this laboratory.

• Asian Pacific Journal of Cancer Prevention
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• v.14 no.11
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• pp.6739-6742
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• 2013

Background: Breast cancer is a major health problem worldwide. Olive oil induces apoptosis in some cancer cells due to phenolic compounds like oleuropein. Although oleuropein has anticancer activity, the underlying mechanisms of action remain unknown. The study aimed to assess the mechanism of oleuropin-induced breast cancer cell apoptosis. Materials and Methods: p53, Bcl-2 and Bax gene expression was evaluated by semi-quantitative reverse transcriptase polymerase chain reaction (RT-PCR) in luminal MCF-7 cells. Results: Oleuropein-induced apoptosis was accompanied by up-regulation of both p53 and Bax gene expression levels and down-regulation in Bcl2. Conclusions: Oleuropein induces apoptosis in breast tumour cells via a p53-dependent pathway mediated by Bax and Bcl2 genes. Therefore, oleuropein may have therapeutic potential in breast cancer patients by inducing apoptosis via activation of the p53 pathway.