• Advances in nano research
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• v.10 no.1
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• pp.15-24
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• 2021

Microtubules (MTs) are the main part of the cytoskeleton in living eukaryotic cells. In this article, a mechanical model of MT buckling, considering the modified strain gradient theory, is analytically examined. The MT is assumed as a cylindrical beam and a new single variable trigonometric beam theory is developed in conjunction with a modified strain gradient model. The main benefit of the present formulation is shown in its new kinematic where we found only one unknown as the Euler-Bernoulli beam model, which is even less than the Timoshenko beam model. The governing equations are deduced by considering virtual work principle. The effectiveness of the present method is checked by comparing the obtained results with those reported by other higher shear deformation beam theory involving a higher number of unknowns. It is shown that microstructure-dependent response is more important when material length scale parameters are closer to the outer diameter of MTs. Also, it can be confirmed that influences of shear deformation become more considerable for smaller shear modulus and aspect ratios.

• Journal of Ocean Engineering and Technology
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• v.36 no.2
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• pp.101-107
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• 2022

Dean (1965) proposed the use of the root mean square error (RMSE) in the dynamic free surface boundary condition (DFSBC) and kinematic free-surface boundary condition (KFSBC) as an error evaluation criterion for wave theories. There are well known wave theories with RMSE more than 1%, such as Airy theory, Stokes theory, Dean's stream function theory, Fenton's theory, and trochodial theory for deep-water waves. However, none of them can be applied for deep-water breaking waves. The purpose of this study is to provide a closed-form solution for deep-water waves with RMSE less than 1% even for breaking waves. This study is based on a previous study (Shin, 2016), and all flow fields were simplified for deep-water waves. For a closed-form solution, all Fourier series coefficients and all related parameters are presented with Newton's polynomials, which were determined by curve fitting data (Shin, 2016). For verification, a wave in Miche's limit was calculated, and, the profiles, velocities, and the accelerations were compared with those of 5^th-order Stokes theory. The results give greater velocities and acceleration than 5^th-order Stokes theory, and the wavelength depends on the wave height. The results satisfy the Laplace equation, bottom boundary condition (BBC), and KFSBC, while Stokes theory satisfies only the Laplace equation and BBC. RMSE in DFSBC less than 7.25×10^-2% was obtained. The series order of the proposed method is three, but the series order of 5^th-order Stokes theory is five. Nevertheless, this study provides less RMSE than 5^th-order Stokes theory. As a result, the method is suitable for offshore structural design.

• Geomechanics and Engineering
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• v.27 no.5
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• pp.465-479
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• 2021

One of the important causes of building and infrastructure failure, such as bridges on pile foundations, is the placement of the piles in liquefiable soil that can become unstable under seismic loads. Therefore, the overarching aim of this study is to investigate the seismic behavior of a soil-pile system in liquefiable soil using three-dimensional numerical FEM analysis, including soil-pile interaction. Effective parameters on concrete pile response, involving the pile diameter, pile length, soil type, and base acceleration, were considered in the framework of finite element non-linear dynamic analysis. The constitutive model of soil was considered as elasto-plastic kinematic-isotropic hardening. First, the finite element model was verified by comparing the variations on the pile response with the measured data from the centrifuge tests, and there was a strong agreement between the numerical and experimental results. Totally 64 non-linear time-history analyses were conducted, and the responses were investigated in terms of the lateral displacement of the pile, the effect of the base acceleration in the pile behavior, the bending moment distribution in the pile body, and the pore pressure. The numerical analysis results demonstrated that the relationship between the pile lateral displacement and the maximum base acceleration is non-linear. Furthermore, increasing the pile diameter results in an increase in the passive pressure of the soil. Also, piles with small and big diameters are subjected to yielding under bending and shear states, respectively. It is concluded that an effective stress-based ground response analysis should be conducted when there is a liquefaction condition in order to determine the maximum bending moment and shear force generated within the pile.

• Structural Engineering and Mechanics
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• v.85 no.3
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• pp.289-304
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• 2023

The main objective of this paper is to study the effect of porosity on the buckling behavior of thick functionally graded sandwich plate resting on various boundary conditions under different in-plane loads. The formulation is made for a newly developed sandwich plate using a functional gradient material based on a modified power law function of symmetric and asymmetric configuration. Four different porosity distribution are considered and varied in accordance with material propriety variation in the thickness direction of the face sheets of sandwich plate, metal foam also is considered in this study on the second model of sandwich which containing metal foam core and FGM face sheets. New quasi-3D high shear deformation theory is used here for this investigate; the present kinematic model introduces only six variables with stretching effect by adopting a new indeterminate integral variable in the displacement field. The stability equations are obtained by Hamilton's principle then solved by generalized solution. The effect of Pasternak and Winkler elastic foundations also including here. the present model validated with those found in the open literature, then the impact of different parameters: porosities index, foam cells distribution, boundary conditions, elastic foundation, power law index, ratio aspect, side-to-thickness ratio and different in-plane axial loads on the variation of the buckling behavior are demonstrated.

• Geomechanics and Engineering
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• v.32 no.2
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• pp.159-177
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• 2023

In the present work, a simple and refined shear deformation theory is used to analyze the effect of visco-elastic foundation on the buckling response of exponentially-gradient sandwich plates under various boundary conditions. The proposed theory includes indeterminate integral variables kinematic with only four generalized parameters, in which no shear correction factor is used. The visco-Pasternak's foundation is taken into account by adding the influence of damping to the usual foundation model which characterized by the linear Winkler's modulus and Pasternak's foundation modulus. The four governing equations for FGM sandwich plates are derived by employing principle of virtual work. To solve the buckling problem, Galerkin's approach is utilized for FGM sandwich plates for various boundary conditions. The analytical solutions for critical buckling loads of several types of powerly graded sandwich plates resting on visco-Pasternak foundations under various boundary conditions are presented. Some numerical results are presented to indicate the effects of inhomogeneity parameter, elastic foundation type, and damping coefficient of the foundation, on the critical buckling loads.

• Steel and Composite Structures
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• v.46 no.3
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• pp.367-383
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• 2023

In this investigation, an improved integral trigonometric shear deformation theory is employed to examine the vibrational behavior of the functionally graded (FG) sandwich plates resting on visco-Pasternak foundations. The studied structure is modelled with only four unknowns' variables displacements functions. The simplicity of the developed model being in the reduced number of variables which was made with the help of the use of the indeterminate integral in the formulation. The current kinematic takes into consideration the shear deformation effect and does not require any shear correction factors as used in the first shear deformation theory. The equations of motion are determined from Hamilton's principle with including the effect of the reaction of the visco-Pasternak's foundation. A Galerkin technique is proposed to solve the differentials governing equations, which enables one to obtain the semi-analytical solutions of natural frequencies for various clamped and simply supported FG sandwich plates resting on visco-Pasternak foundations. The validity of proposed model is checked with others solutions found in the literature. Parametric studies are performed to illustrate the impact of various parameters as plate dimension, layer thickness ratio, inhomogeneity index, damping coefficient, vibrational mode and elastic foundation on the vibrational behavior of the FG sandwich plates.

• Korean Journal of Applied Biomechanics
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• v.25 no.2
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• pp.175-182
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• 2015

Objective : The purpose of this study was to investigate difference in fascicle behavior of the medial gastrocnemius during the locomotion with varying intensities, such as gait and one-legged and two-legged vertical jumping. Methods : Six subjects (3 males and 3 females; age: $27.2{\pm}1.6yrs.$, body mass: $62.8{\pm}9.8kg$, height: $169.6{\pm}8.5cm$) performed normal gait (G) at preferred speed and maximum vertical jumping with one (OJ) and two (TJ) legs. While subjects were performing the given tasks, the hip, knee and ankle joint motion and ground reaction force was monitored using a 8-infrared camera motion analysis system with two forceplates. Simultaneously, electromyography of the triceps surae muscles, and the fascicle length of the medial gastrocnemius were recorded using a real-time ultrasound imaging machine. Results : Comparing to gait, the kinematic and kinetic parameters of TJ and OJ were found to be significantly different. Along with those parameters, change in the medial gastrocnemius (MG) muscle-tendon complex (MTC) length ($50.57{\pm}6.20mm$ for TJ and $44.14{\pm}5.39mm$ for OJ) and changes in the fascicle length of the MG ($18.97{\pm}3.58mm$ for TJ and $20.31{\pm}4.59mm$ for OJ) were observed. Although the total excursion of the MTC and the MG fascicle length during the two types of jump were not significantly different, however the pattern of length changes were found to be different. For TJ, the fascicle length maintained isometric longer during the propulsive phase than OJ. Conclusion : One-legged and two-legged vertical jumping use different muscle-tendon interaction strategies.

• Journal of Korean Society of Transportation
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• v.35 no.5
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• pp.396-408
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• 2017

In Korea, the number of elderly has been increasing rapidly. So it is also expected that the economic activity and the trip frequency of the elderly will increase. On the other hand, elderly related accidents such as falls during walking are steadily increasing and the satisfaction about pedestrian environment of elderly is very low. In this paper, we found one of the reasons for these dissatisfaction in pedestrian facility, which is not considering the walking ability (about 75% of non-elderly person) of the elderly. So, we analyze the kinematic walking characteristics of the elderly with the motion analysis system, when the elderly use stairs. As a result of analysis of various walking variables, the current standard for stairway height in Korean law (18cm) requires excessive force to elderly so it was difficult for elderly to keep the balance of the body in ascending and descending walk of stairs. In this paper, we propose the stair design criteria through the cluster analysis of walking parameters reflecting the gait characteristics of the elderly. This change is not a big for non-elderly person, but it can promote more socioeconomic activities for the elderly.

• Korean Journal of Applied Biomechanics
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• v.16 no.1
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• pp.101-108
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• 2006

The purpose of this study was to compare GRF characteristics during walking wearing jogging and roller shoes. Twelve male middle school students (age: $15.0{\pm}0.0\;yrs$, height: $173.6{\pm}5.0\;cm$, weight: $587.6{\pm}89.3\;N$) who have no known musculoskeletal disorders were recruited as the subjects. Kinematic data from six S-VHS camcorders(Panasonic AG456, 60 fields/s) and GRF data from two force platform; (AMII OR6-5) were collected while subjects walked wearing roller and jogging shoes in random order at a speed of 1.1 m/s. An event sync unit with a bright LED light was used to synchronize the video and GRF recordings. GRF data were filtered using a 20 Hz low pass Butterworth. digital filter and further normalized to the subject's body weight. For each trial being analyzed, five critical instants and four phases were identified from the recording. Temporal parameters, GRFs, displacement of center of pressure (DCP), and loading and decay rates were determined for each trial. For each dependent variable, paired t-test was performed to test if significant difference existed between shoe conditions (p <.05). Vertical GRFs at heel contact increased and braking forces at the end of initial double limb stance reduced significantly when going from jogging shoe to roller shoe condition. Robbins and Waked (1997) reported that balance and vertical GRF are closely related It seems that the ankle and knee joints are locked in an awkward fashion at the heel contact to compensate for the imbalance. The DCP in the antero-posterior direction for the roller shoe condition was significantly less than the corresponding value for the jogging shoe condition. Because the subjects tried to keep their upper body weight in front of the hip to prevent falling backward, the DCP for the roller shoe condition was restricted The results indicate that walking with roller shoes had little effect on temporal parameters, and loading and decay rates. It seems that there are differences in GRF characteristics between roller shoe and jogging shoe conditions. The differences in GRF pattern may be caused primarily by the altered position of ankle, knee, and center of mass throughout the walking cycle. Future studies should examine muscle activation patterns and joint kinematics during walking with roller shoes.

• Journal of Ginseng Research
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• v.41 no.4
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• pp.578-588
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• 2017

Background: Elevated testicular temperature disrupts spermatogenesis and causes infertility. In the present study, the protective effect of enzymatically biotransformed Panax ginseng Meyer by pectinase (GINST) against chronic intermittent heat stress-induced testicular damage in rats was investigated. Methods: Male Sprague-Dawley rats (4 wk old, 60-70 g) were divided into four groups: normal control (NC), heat-stress control (HC), heat-stress plus GINST-100 mg/kg (HG100), and heat-stress plus GINST-200 mg/kg (HG200) treatment groups. Each dose of GINST (100 mg/kg and 200 mg/kg) was mixed separately with a regular pellet diet and was administered orally for 24 wk. For inducing heat stress, rats in the NC group were maintained at $25^{\circ}C$, whereas rats in the HC, HG100, and HG200 groups were exposed to $32{\pm}1^{\circ}C$ for 2 h daily for 6 mo. At week 25, the testes and serum from each animal were analyzed for various parameters. Results: Significant (p < 0.01) changes in the sperm kinematic values and blood chemistry panels were observed in the HC group. Furthermore, spermatogenesis-related molecules, sex hormone receptors, and selected antioxidant enzyme expression levels were also altered in the HC group compared to those in the NC group. GINST (HS100 and HS200) administration significantly (p < 0.05) restored these changes when compared with the HC group. For most of the parameters tested, the HG200 group exhibited potent effects compared with those exhibited by the HG100 group. Conclusion: GINST may be categorized as an important medicinal herb and a potential therapeutic for the treatment of male subfertility or infertility caused by hyperthermia.