• Journal of the Korea Institute of Building Construction
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• v.23 no.6
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• pp.673-682
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• 2023

This study investigates the delay in setting characteristics of mortar influenced by variations in super retarding agent(SRA) content, curing temperature, and strength levels. Utilizing a settimeter, the research introduces an objective approach to accurately determine the setting time of concrete with SRA under diverse environmental and material mixing conditions at construction sites. The findings indicate that the settimeter, in conjunction with a nonlinear regression model, can effectively estimate the setting time of super retarding mortar. Optimal management of the initial setting is recommended at approximately 45ST and the final setting around 80ST. This methodology enables more effective quality control in the setting times of super retarding concrete.

• Journal of Korean Dental Hygiene Science
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• v.1 no.1
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• pp.57-63
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• 2018

The coffee demand market in Korea is growing every year, and the adults drink an average of one cup of coffee every day. In order to investigate the effect of coffee on oral malodor, 15 Korean subjects were recruited. There were no significant differences in the values of oral malodor using BB checker(Taiyo, Japan) in the factors of sex, smoking, drinking, feeling oral malodor by themselves, feeling oral malodor by others, periodic scaling, activity of Streptococcus mutans, bleeding on probing, and coffee drinking habits. Patient hygiene performance index, calculus index, index of coat on the tongue, toothbrushing time, toothbrushing frequency had no correlation with oral malodor. The difference between before and after drinking coffee with syrup(17.93±16.54) was significant, but the difference between before and after drinking coffee without syrup(1.13±14.75) was not significant. We suggested the cause of oral malodor after drinking coffee was syrup, but not coffee.

• The Korean Journal of Emergency Medical Services
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• v.28 no.1
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• pp.47-62
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• 2024

Purpose: This study aimed to provide basic data for infection control education plans based on infection control awareness and performance of paramedic students during clinical field training. Methods: Data were collected from paramedic students with experience in clinical field training. The data collection period was from May 4, 2023, to June 4, 2023, and 132 copies of the collected survey were analyzed using the SPSS27.0 program. Results: Infection control awareness and performance were 4.80±0.24 points and 4.49±0.55 points out of 5, respectively. The infection control awareness of the participants according to clinical field training-related characteristics differed significantly in university education before clinical field training (t=2.100, p=.038). In addition, there were significant differences in performance in the number of clinical field training sessions (F=9.149, p=.000), hospital education before clinical field training (t=5.365, p=.000), and hospital education during clinical field training (t=3.094, p=.002). Conclusion: Before clinical field training, schools should provide infection control education that combines theory and practice suitable for hospital practice so that students can complete the infection control education organized by the hospital. Furthermore, if a university develops infection control in the clinical field training guidelines, it will have a positive impact on students' infection control performance through prior education.

• IMMUNE NETWORK
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• v.22 no.2
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• pp.20.1-20.9
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• 2022

Despite the high prevalence of chronic dermatitis and the accompanied intractable itch, therapeutics that specifically target itching have low efficacy. Increasing evidence suggests that TLRs contribute to immune activation and neural sensitization; however, their roles in chronic itch remain elusive. Here, we show that the RBL-2H3 mast cell line expresses TLR4 and that treatment with a TLR4 antagonist opposes the LPS dependent increase in mRNA levels of Th2 and innate cytokines. The pathological role of TLR4 activation in itching was studied in neonate rats that developed chronic itch due to neuronal damage after receiving subcutaneous capsaicin injections. Treatment with a TLR4 antagonist protected these rats with chronic itch against scratching behavior and chronic dermatitis. TLR4 antagonist treatment also restored the density of cutaneous nerve fibers and inhibited the histopathological changes that are associated with mast cell activation after capsaicin injection. Additionally, the expression of IL-1β, IL-4, IL-5, IL-10, and IL-13 mRNA in the lesional skin decreased after TLR4 antagonist treatment. Based on these data, we propose that inhibiting TLR4 alleviated itch in a rat model of chronic relapsing itch, and the reduction in the itch was associated with TLR4 signaling in mast cells and nerve fibers.

• Journal of Korean Medicine Rehabilitation
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• v.34 no.1
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• pp.97-108
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• 2024

Objectives The purpose of this study was to investigate the effectiveness and safety of herbal medicine treatment for Colles fractures through a systematic review and to provide evidence for applying herbal medicine treatment. Methods We searched for papers published from January 1, 2018 to October 18, 2023, in PubMed and China National Knowledge Infrastructure based on the keyword 'Colles fracture', 'Chinese traditional medicine', 'Chinese medicine', 'herbal medicine', 'drugs, chinese herbal', 'kampo', 'decoction', 'capsule', 'powder'. Results A total of 51 studies were searched at first research. Then the studies were screening according to the criteria, and 13 studies were finally selected. The oriental medical intervention analyzed in this study was an orally administered herbal medicine. Conclusions Studies have shown that herbal medicine has a significant effect on Colles fractures. However, all studies were assessed as having a high risk of bias. In the future, further well-designed studies are needed to demonstrate the effectiveness of herbal medicine for Colles fractures and reduce the risk of bias.

• Archives of Metallurgy and Materials
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• v.65 no.3
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• pp.1111-1116
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• 2020

Graphitic carbon nitride (g-C₃N₄) is an attractive photocatalyst, however, its practical photocatalytic applications are still faced with huge challenges. The aim of this research is to identify the correlation between synthetic conditions and properties of the g-C₃N₄ and derive an optimum synthesis condition for improving photocatalytic activities of the g-C₃N₄. In this study, novel and versatile g-C₃N₄ nanosheets were synthesized by the simple thermal pyrolysis of urea. In the synthesis process, the pyrolysis temperature and the heating rate, which can have the most significant influence on the structures and properties of g-C₃N₄, were set as variables, and the effects were systematically investigated. When synthesized at a relatively high temperature, the amount of material being synthesized is reduced, however it has been found to represent optical properties suitable for highly efficient photo-catalyst by the increase in the thickness and defects formed in the g-C₃N₄ nanosheets. The photocatalytic degradation experiment of MB dyes indicated that the highest degradation of 95.2% after the reaction for 120 min was achieved on the g-C₃N₄ nanosheets synthesized at 650℃.

• Tuberculosis and Respiratory Diseases
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• v.66 no.6
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• pp.444-450
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• 2009

Background: Biomarkers for cancer have several potential clinical uses, including the following: early cancer detection, monitoring for recurrence prognostication, and risk stratification. However, no biomarker has been shown to have adequate sensitivity and specificity. Many investigators have tried to validate biomarkers for the early detection and recurrence of lung cancer. To evaluate plasma G-CSF as such a biomarker, protein levels were measured and were found to correlate with the clinicopathological features of primary lung tumors. Methods: Between December 2006 and May 2008, 100 patients with histologically-validated primary lung cancer were enrolled into this study. To serve as controls, 127 healthy volunteers were enrolled into this study. Plasma G-CSF levels were measured in lung cancer patients using the sandwich ELISA system (R & D inc.) prior to treatment. Results: The mean plasma G-CSF levels were 12.2$\pm$0.3 pg/mL and 46.0$\pm$3.8 pg/mL (mean$\pm$SE) in the normal and in the cancer groups, respectively. In addition, plasma G-CSF levels were higher in patients with early lung cancer than in healthy volunteers (p<.001). Plasma G-CSF levels were higher in patients who were under 65 years old or smokers. Within the cancer group, plasma G-CSF levels were higher in patients with non small cell lung cancer than in patients with small cell lung cancer (p<.05). Overall, plasma G-CSF levels were shown to increase dependent upon the type of lung cancer diagnsosed. In the order from highest to lowest, the levels of plasma G-CSF tended to decrease in the following order: large cell carcinoma, squamous cell carcinoma, adenocarcinoma, and bronchioloalveolar carcinoma. Plasma G-CSF levels tended to be higher in patients with advanced TNM stage than in localized TNM stage (I, II

• Korean journal of applied entomology
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• v.58 no.3
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• pp.219-224
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• 2019

The super mealworm, Zophobas morio, is mainly used as food for pets, fish, reptiles, amphibians, birds, and as snacks. An experiment was conducted to investigate the effects of temperature, supplementary feeding, and spawning interval on super mealworm rearing. To efficiently rear this species, the insects were bred at a temperature of $27^{\circ}C$ or higher and reached a weight of over 0.6 g at 80 days after hatching. Supplementary feed (with high protein content: 10% of soybean meal and 10% of fish meal) enabled larvae to reach a weight of over 0.7 g at 80 days after hatching. Mass rearing of super mealworm requires increase in egg production (i.e., high yield) and uniformity of larvae. Adults were transferred to spawning bases every 5, 10, or 15 days (three treatments), which resulted in a total of 7,256, 5,439, 2,060 hatched larvae, respectively. It is possible to obtain more than 7,000 larvae by transferring the egg-laying frame to the spawning base at intervals of 5 days and with nine spawning operations; this procedure generates larvae weighing over 0.68 g each.

• The Journal of KAIRB
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• v.6 no.1
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• pp.17-31
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• 2024

Purpose: This study aims to develop preliminary items for measuring the perceived service quality of clinical trials among participants and to verify content validity. Methods: This study was designed as a methodological study. A conceptual framework was established based on Brady and Cronin's hierarchical model, and preliminary items were prepared through translation-back-translation, a review of existing instruments, and in-depth interviews with clinical trial participants and clinical research coordinators. The final items were completed through content validity testing by experts and a review of items by clinical trial participants for the prepared preliminary items. Results: Through this study, a set of 58 items across four domains (quality of interaction with researchers, the physical environment, performance procedures, and performance results) and 9 components (information·education·communication, trust, respect for participant preferences, securing facilities and space, accessibility, comfortability, informed consent, coordination of care, subjective understanding of clinical trials) on the service quality of clinical trials were completed. The scale content validity index of all preliminary items was 0.96, meeting the recommended standards. The individual-item content validity index also meets the recommended criteria for most items, excluding four items. Conclusion: This study holds significance in developing items to measure the quality of clinical trial execution from the perspective of participants. By verifying the reliability and validity of these items through subsequent research, it is expected that they can be utilized as a valuable instrument to devise strategies for improving the quality of clinical trials.

• Clinical and Experimental Reproductive Medicine
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• v.44 no.3
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• pp.152-158
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• 2017

Objective: To identify the associations between polymorphisms of the 3'-untranslated region (UTR) of methylenetetrahydrofolate reductase (MTHFR) gene, which codes for an important regulatory enzyme primarily involved in folate metabolism, and idiopathic recurrent pregnancy loss (RPL) in Korean women. Methods: The study population comprised 369 RPL patients and 228 controls. MTHFR 2572C > A, 4869C > G, 5488C > T, and 6685T > C 3'-UTR polymorphisms were genotyped by polymerase chain reaction-restriction fragment length polymorphism analysis or by TaqMan allelic discrimination assays. Natural killer cell proportions were determined by flow cytometry. Results: The MTHFR 2572-5488-6685 (A-C-T) haplotype had an adjusted odds ratio of 0.420 (95% confidence interval, 0.178-0.994; p= 0.048) for RPL. Analysis of variance revealed that MTHFR 4869C > G was associated with altered $CD56^+$ natural killer cell percentages (CC, $17.91%{\pm}8.04%$; CG, $12.67%{\pm}4.64%$; p= 0.024) and folate levels (CC, $12.01{\pm}7.18mg/mL$; CG, $22.15{\pm}26.25mg/mL$; p= 0.006). Conclusion: Variants in the 3'-UTR of MTHFR are potential biomarkers for RPL. However, these results should be validated in additional studies of ethnically diverse groups of patients.