• 제목/요약/키워드: Ki-66

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Rice genes specifically expressed in a rice mutant gained resistance to rice blast.(oral)

  • C. U. Han;Lee, C. H.;K. S. Jang;Park, Y. H.;H. K. Lim;Kim, J.C.;Park, G. J.;J.S. Cha;Park, J. E.
    • Proceedings of the Korean Society of Plant Pathology Conference
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    • 2003.10a
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    • pp.66.2-66
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    • 2003
  • A gain-of-function mutant, SHM-11 obtained through gamma-ray mutagenesis, is resistant to rice blast caused by Magnaporthe grisea while wild type Sanghaehyanghyella is highly susceptible to the same disease. The resistance in the mutant was not race-specific when we tested with four races (KJ-201, KI-1113a, KI-313, KI-409) of M. grisea. To identify genes involved disease resistance in the gain-of-function mutant, genes specifically expressed in the mutant were selected by suppression subtractive hybridization using cDNAS of blast-inoculated mutant and wild type as a tester and a driver, respectively, Random 200 clones from the subtracted library were selected and analyzed by DNA sequencing. The sequenced genes represented three major groups related with disease resistance; genes encoding PR proteins, genes probably for phytoalexin biosynthesis, and genes involved in disease resistance signal transduction. A gene encoding a putative receptor-like protein kinase was identified as highly expressed only in the gain-of-function mutant after blast infection. The role of the putative receptor-like protein kinase gene during blast resistance will be further studied.

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Ki-67 is a Valuable Prognostic Factor in Gliomas: Evidence from a Systematic Review and Meta-analysis

  • Chen, Wen-Jie;He, De-Shen;Tang, Rui-Xue;Ren, Fang-Hui;Chen, Gang
    • Asian Pacific Journal of Cancer Prevention
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    • v.16 no.2
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    • pp.411-420
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    • 2015
  • Ki-67 has been widely used as an indicator of cell proliferation in gliomas. However, the role of Ki-67 as a prognostic marker is still undefined. Thus, we conducted a meta-analysis of the published literatures in order to clarify the impact of Ki-67 on survival in glioma cases. Eligible studies were identified in PubMed, EMBASE, ISI Web of Science, Cochrane Central Register of Controlled Trials, Science Direct and Wiley Online Library with the last search updated on August 31, 2014. The clinical characteristics, overall survival (OS) and progression-free survival (PFS) together with Ki-67 expression at different time points were extracted. A total of 51 studies, covering 4,307 patients, were included in the current meta-analysis. The results showed that overexpression of Ki-67 can predict poor OS (HR=1.66, 95%CI: 1.53-1.80; Z=11.87; p=0.000) and poor PFS (HR=1.67, 95%CI: 1.47-1.91; Z=7.67; p=0.000) in gliomas. Moreover, subgroup analyses also indicated that high level of Ki-67 expression was related to poor OS and PFS in glioma patients regardless of region, pathology type, cut-off value and statistical method. In conclusion, the current meta-analysis revealed that Ki-67 expression might be a predicative factor for poor prognosis of glioma patients, emphasizing its importance as a predictor.

A Study on the Self-Diagnosis Criteria of Electrical Installations (자가용 전기설비의 자가진단 기준에 대한 연구)

  • Kim, Jong-Min;Lee, Hyeon-Woo;Kim, Hong-Ki;Yoo, Sang-Bong;Jang, Kyung-Bae
    • The Transactions of The Korean Institute of Electrical Engineers
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    • v.66 no.5
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    • pp.863-869
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    • 2017
  • This paper is to enable electrical safety manager to have more objective evaluation on the safety by indicating quantitative values such as life-time and status quotient of daily visual inspection on private electrical equipments. Self-diagnosis table is recommended to apply such a evaluation efficiently according to the characteristics of each electrical equipments, and the managers's determination of the precise inspection, replacement etc. will be also possible through the standard selected by various domestic and foreign data with expert's advise for numerical evaluation. This circumstance will be able to establish the foundation to secure the soundness of electrical equipments.

Wind Tunnel Test on Propellers for Middle Size Electric Propulsion UAV (중형 전기추진 무인기용 프로펠러 풍동시험)

  • Park, Poo-Min;Hwang, Oh-Sik;Kim, Young-Mun;Kim, Chun-Taek;Kwon, Ki-Jung
    • Proceedings of the Korean Society of Propulsion Engineers Conference
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    • 2011.11a
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    • pp.784-788
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    • 2011
  • Wind tunnel test on 20" class propellers are carried out at KARI's low speed wind tunnel (LSWT). The test was done to select most efficient propeller for middle size electric propulsion UAV of KARI. The propellers are commercially available 20" class folding type propellers made of carbon fiber composite material. As the result, 21"${\times}$15.5" propeller was selected whose efficiency is 66% at cruise condition.

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Surgical Experience of Neglected Lower Cervical Spine Fracture in Patient with Ankylosing Spondylitis

  • Jo, Dae-Jean;Kim, Sung-Min;Kim, Ki-Tack;Sea, Eun-Min
    • Journal of Korean Neurosurgical Society
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    • v.48 no.1
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    • pp.66-69
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    • 2010
  • The management of lower cervical fractures in patients with ankylosing spondylitis (AS) differs from normal cervical fractures. Patients with AS are highly susceptible to extensive neurologic injuries and spinal deformities after cervical fractures from even minor traumatic forces. These injuries are uniquely complex, require careful imaging assessment, and aggressive surgical management to optimize spinal stability and functional outcomes.

Ordinary Smooth Topological Spaces

  • Lim, Pyung-Ki;Ryoo, Byeong-Guk;Hur, Kul
    • International Journal of Fuzzy Logic and Intelligent Systems
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    • v.12 no.1
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    • pp.66-76
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    • 2012
  • In this paper, we introduce the concept of ordinary smooth topology on a set X by considering the gradation of openness of ordinary subsets of X. And we obtain the result [Corollary 2.13] : An ordinary smooth topology is fully determined its decomposition in classical topologies. Also we introduce the notion of ordinary smooth [resp. strong and weak] continuity and study some its properties. Also we introduce the concepts of a base and a subbase in an ordinary smooth topological space and study their properties. Finally, we investigate some properties of an ordinary smooth subspace.

A Study on the Instantaneous Characteristics Analysis Method of PMSM using Slot Equivalent Circuit (슬롯등가회로를 이용한 영구자석모터의 순시치 해석법연구)

  • Won, Sung Hong;Han, Ki-Soo
    • The Transactions of the Korean Institute of Electrical Engineers P
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    • v.66 no.1
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    • pp.1-6
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    • 2017
  • Recently, many motor analysis methods have been developed and studied. Among these methods, the finite element method(FEM) and the analytic method are most popular in field engineers because of the accuracy of FEM and the convenience and rapid analysis time of the analytic method. Contrary, the finite element method has a weakness in calculation time and it is not easy to obtain the instantaneous characteristics value of motor with the analytic method. In this paper, the authors proposes a novel method for calculating the instantaneous characteristics of motors with the magnetic slot equivalent circuit.

The Effect of Ti and Sn Contents on the Shear Bonding Strength of Brazing Joint of YSZ to STS430 using Ag Based Filler Metals (Ag계 Filler Metal을 사용한 YSZ와 STS430의 브레이징 접합시 Ti, Sn의 함량 변화가 접합강도에 미치는 영향)

  • Lee, Ki Young;Park, Hyun Gyoon
    • Journal of Welding and Joining
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    • v.32 no.1
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    • pp.66-70
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    • 2014
  • In Ti active brazing of YSZ to STS 430 using Ag-Cu Filler Metal, the effect of Ti contents on the shear bonding strength were investigated together with the effect of brazing temperature and holding time. The addition of Ti in Ag-Cu Filler Metal increased the bonding strength up to 4.68% Ti, followed by the decrease with further addition. This seems to be caused by formation of TixOy at the reaction layer. Brazing temperature was optimized at $960^{\circ}C$ among a given temperature ranges. The addion of Sn to Ag-Cu filler metal brought the decrease of its melting temperature its melting temperature without a significant decrease of bonging strength.

Survey on Electricity Safety of Thermal Power Plants by Korean Industrial Safety and Health Act (산업안전보건법에 의한 화력발전소의 전기안전 실태 조사 분석)

  • Kim, Ki-Young;Ji, Pyeong-Shik
    • The Transactions of the Korean Institute of Electrical Engineers P
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    • v.66 no.2
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    • pp.88-93
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    • 2017
  • Thermal power plants play an important role in the country's power supply, but often violate the Industrial Safety and Health Act due to lack of safety awareness about the incompatibility of electrical safety and safety facilities. In this study, safety diagnosis was performed for each of the five major thermal power plants in Korea. For the 18 sites including coal, LNG, and power plants, we investigate the main violations of Article 327 and conduct intensive analysis on repetitive electrical safety violations to propose preventive measures that meet the characteristics of the power plant.

Noise Improvement Countermeasure by Noise Pattern Analysis for Electrical and Electronic Equipment (전기전자 기기의 노이즈 패턴 분석에 의한 노이즈 개선 대책)

  • Cho, Dae-Hoon;Lee, Ki-Sik
    • The Transactions of The Korean Institute of Electrical Engineers
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    • v.66 no.1
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    • pp.194-202
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    • 2017
  • In this study, we measured and analyzed electrical noise signals present in devices and systems operated in industrial facilities. Based on the analytic findings, we studied the most effective improvement measures for eliminating such noise signals. Leakage current and ground current generate data interferences in communication systems, and therefore we measured leakage current and ground current. We also measured and analyzed electrical noises in power systems to predict noise pathways and interference routes. Furthermore, we proposed the most effective and reliable improvement measures for blocking off various noise signals and safely eliminating them by improving the internal wiring of the facilities and grounding systems. As a final step, we conducted the proposed improvement measures and confirmed that they helped to improve the operations of the device sand systems in service by re-measuring electrical noise signals and comparing them with those measured before the proposed improvement measures were implemented.