• Title/Summary/Keyword: Ki-66

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A Study on the Manufacturing Method of Natural Stretch Yarns using Nylon 66 (Nylon 66를 이용한 Natural Stretch Yarns 제조방법에 관한 연구)

  • Park, Seong-Woo;Seo, Mal-Yong;Hong, Sang-Ki;Choi, Hae-Chung;Choi, Bo-Yun
    • Proceedings of the Korean Society of Dyers and Finishers Conference
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    • 2011.03a
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    • pp.96-96
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    • 2011

  • 본 연구에서는 스포츠 캐주얼 웨어(스노우보드복, 골프복, 등산복 등)로 사용되는 신축성 소재의 개발로 Stretch성을 부여하기 위하여 Nylon 66 POY 소재의 가연가공 기술을 통하여 Mechanical Stretch 성능이 발현되는 소재를 개발하고자 한다. 섬유소재에 일반적으로 신축성을 부여하기 위해서는 Spandex(Polyurethane, PU)를 방적공정에서 복합 제조하는 Core Yarn과 장섬유에 Spandex를 피복하는 Covering Yarn(직물용) 형태가 있는데, Spandex로 인한 신축성은 200~800% 발현되나 PU를 사용함에 따라서 공정추가에 대한 원가상승, 균제도 불량, 몰림현상 및 PU 수축에 의한 중량감이 있으며, 또한 PU에 의한 견뢰도불량, 피복사의 벗겨짐성 등 외관상 트러블 발생빈도가 높다. 이에 따라 Spandex를 사용하지 않고 단일소재로서 사가공기술에 의해 Stretch성이 부여되는 소재를 개발하고 이의 기술을 상용화 하고자 한다. Nylon 66 POY 소재를 Disc 가연기, Pin 가연기 등의 설비를 이용하여 70d급 원사의 가연가공 공정을 진행하였다. 그리고 개발된 원사의 섬도(d), 강도(g/d), 신도(%), 크림프율(%)의 물성 시험을 통하여 Nylon66의 공정상 변화인자에 따른 기본 물성 및 Stretch 발현성을 분석하여 최적의 설비 및 공정조건을 확립하였다.

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Expression of p53 and Ki-67 in Cervical Dysplasia with Human Papilloma Virus Infection or Non-infection (인유두종 바이러스의 감염 또는 감염되지 않은 자궁 경부 이형성증에서 p53 및 Ki-67의 발현)

  • Choi, Sook-Kyung;Kim, Tai Jeon;Hong, Seung Bok;Lee, Hun Taeck
    • Korean Journal of Clinical Laboratory Science
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    • v.36 no.2
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    • pp.178-184
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    • 2004

  • This research focuses on the overall evaluation of tumor protein (p53) and cell growth marker (Ki-67) in their functions as carcinogenic factors in both a HPV-infected group and in a HPV-noninfected group with the precancerous dysplasia of uterine cervix. Histological grades were determined by the H&E staining and the expression level of p53 and Ki-67 were tested by the immunohistochemistry method. The results were as follows. Among the total of 66 cases, p53 (+) was observed in 19 cases (29.0%) from the mild grade group, 22 cases (33.0%) from the moderate grade group, and 19 cases (29.0%) from the severe grade group. The values correlate with the increase of dysplasia intensity in HPV-noninfected group and showed significant correlation (p<0.05), but there were no significant difference from the HPV-infected group. Among a total of 66 cases, the mitotic index of Ki-67 (+) were observed in 19 cases (29.0%) from the mild grade group, 22 cases (33.0%) from the moderate grade group, and 19 cases (29.0%) from the severe grade group. The values were significantly different against dysplasia intensity (p<0.05), but showed no significant difference from HPV infection. After cross comparing the statistical parameters of p53 and ki-67 in their significance, p53 was shown to be statistically significant with Ki-67 while there was no statistically significant difference with Ki-67 (p<0.05). Taken together, tumor protein (p53) and an index of Ki-67 observed in cervical dysplasia and in HPV related dysplasia of cervix uterine did not have any notable significance with HPV infection. The incidence rate of p53, however, had some significant correlation with dysplasia while Ki-67 had no particular statistical significance. As a result, p53 and Ki-67 can be considered as effective diagnostic markers in predicting the disease progression of dysplasia to cervical cancer.

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Association with Recurrence of Giant cell Tumor of Bone Between Immunohistochemical Marker (MCM3, Ki-67 and HH3) Expression Rate (골의 거대세포종양의 재발과 면역조직화학적 표지자(MCM3, Ki-67 그리고 HH3)의 발현율과의 연관성)

  • Ha, Jong-Kyoung;Jeong, Hoon;Kim, Yong-Ju;Lee, Kwan-Hee;Choi, Kyoung-Eob
    • The Journal of the Korean bone and joint tumor society
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    • v.13 no.2
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    • pp.67-74
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    • 2007

  • Purpose: To evaluate association of giant cell tumors recurrence between markers of proliferation cells (MCM3, Ki-67 and HH3) Materials and Methods: Ten case of giant cell tumor of bone were reviewed. The patients were six males and four females (mean age: 33 yrs). All patients were done operation after biopsy. The radiologic grading was determined according to Enneking grading system. The immunohistochemical stains of MCM3, HH3, and Ki-67 were done with Microarray block. Results: The three cases of 10 cases (30%) were recurred at same sites. Two case of recurrence was grade II according to radiologic features. The remaining case was grade I. The expression rate of immunohistochemical markers in radiologic grade 2 and 3 were more increased than grade 1. But there was not association between radiologic grading and proliferation of tumor cells because result data was not coherence. Mean MCM3 labeling index of non-recurred case was 11.2%, recurred case was 7.2%. Ki-67 was 12% vs. 8.9%, respectively and HH3 was 66.9 % vs. 75.4%, respectively. Thus there was no association between local recurrence and immunohistochemical Ki-67, MCM3 expression rate. But HH3 marker expression rate was increased in recurred cases compared to non-recurred cases. Conclusion: Our study suggests that HH3 immunohistochemical marker can be a useful prognostic factor.

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