• 한국중재학회지:중재연구
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• 제13권2호
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• pp.353-376
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• 2004

In the inner turn key constructions the problems of uniform types are repeatedly occurred, and, especially, many problems happen up to the stage of pre-construction(from a bid to a contract) owing to the specialties of the turn key constructions. So the claim factors of the Korean turn key constructions were abstracted through the literature searches, the site document examinations, the case studies and the interviews with the experts. When the technicians meeting the interior turn key constructions for the first time and working here now are well acquainted with only these factors, many claims will be prevented. By analysing the degree of claims by claims factors through the questionnaires to the experts about the abstracted factors and surveying the amount of the claims through the case studies, what factors exerted how much of influence on the claims was tested and analyzed. Proposing the response devices to the factors affecting the claims much led the technicians in charge of internal turn key constructions to the prevention and the proper solution of the site claims.

• Earthquakes and Structures
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• 제13권6호
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• pp.573-588
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• 2017

The earthquake input is required when the soil-structure interaction (SSI) analysis is performed by the direct finite element method. In this paper, the earthquake is considered as the obliquely incident plane body wave arising from the truncated linearly elastic layered half space. An earthquake input method is developed for the time-domain three-dimensional SSI analysis. It consists of a new site response analysis method for free field and the viscous-spring artificial boundary condition for scattered field. The proposed earthquake input method can be implemented in the process of building finite element model of commercial software. It can result in the highly accurate solution by using a relatively small SSI model. The initial condition is considered for the nonlinear SSI analysis. The Daikai subway station is analyzed as an example. The effectiveness of the proposed earthquake input method is verified. The effect of the obliquely incident earthquake is studied.

• Wind and Structures
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• 제25권2호
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• pp.195-214
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• 2017

Full-scale wind characteristics based on the field measurements is an essential element in structural wind engineering. Statistical analysis of the wind characteristics at Sutong Cable-stayed Bridge (SCB) site is conducted in this study with the recorded long-term wind data from structural health monitoring system (SHMS) between 2008 and 2015. Both the mean and turbulent wind characteristics and power spectra are comprehensively investigated and compared with those in the current codes of practice, such as the measured wind rose diagram, monthly maximum mean wind speed, turbulence intensity, integral length scale. Measurement results based on the monitoring data show that winds surrounding the SCB site are substantially influenced by the southeast monsoon in summer and strong northern wind in winter. The measured turbulence intensity is slightly higher than the recommended values in specifications, while the measured ratio of lateral to longitudinal turbulence intensity is slightly lower. An approximately linear relationship between the measured turbulence intensities and gust factors is obtained. The mean value of the turbulence integral length scale is smaller than that of typical typhoon events. In addition, it is found that the Kaimal spectrum is suitable to be adopted as the power spectrum for longitudinal wind component at the SCB site. This contribution would provide important wind characteristic references for the wind performance evaluation of SCB and other civil infrastructures in adjacent regions.

• 한국지반공학회:학술대회논문집
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• 한국지반공학회 2007년 가을학술발표회
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• pp.639-653
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• 2007

Offshore geotechnical site investigation of the seabed ground has been a key factor of the successful construction of various types of offshore structures like as sea-crossing bridges, submerged tunnels, and other marine facilities. Offshore investigations are not easy tasks because of the wave, wind, tidal ebb and flows, and others. Recent developments of offshore equipment including platforms and testing devices like as maine cone penetrator have inspired us to get more reliable characteristics of the seafloor. General information on the offshore site investigations and technical trends concerned are introduced.

• 한국건설관리학회논문집
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• 제8권6호
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• pp.246-262
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• 2007

The performance of projects has always been an area of interest in the construction industry. Roles of all construction supply chain partners are necessary; however the role of a contractor firm in the construction project is pivotal. So, this research intended to explore a Construction Firm's performance criteria which could measure the level of performance of that firm in an ongoing project. Data was collected from construction professionals working in three principal project participant organizations, namely Owner, Consultant and Contractor. A total of 113 nos. of performance measuring items were sorted from literature review and used to collect data. Statistical tools processed by SPSS program was employed to analyze the data. Out of total 113 items, only 65 nos. of variables were found to be acceptable to every population group of this study. Factor analysis revealed 12 key performance predicting factors (KPPF) with 53 predictive indicators. 12 KPPFS with index weight are: work progress and smoothening (9.3%), change order management and work accuracy (9.1%), business relationship building (8.1%), adequacy of construction work procedure (8.6%), quality performance (8.0%), health and site safety adequacy (8.8%), Innovative contractor (8.0%), adequacy of construction site information (6.8%), compliance with contract plan/specification requirements (8.9%), creditworthiness and financial capability (8.3%), intra-agency relationship and responsiveness (7.0%) and resource management (9.2%). These results could be useful to project management body to evaluate performance of its contractor firm on site as well as the contractor itself to assess own performance and its subcontractors on-site.

• Archives of Pharmacal Research
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• 제23권1호
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• pp.31-34
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• 2000

An efficient procedure for the preparation of 7,8-dichloro-6-nitro-1H-1,5-benzodiazepine-2,4-(3H, 5H)-dione(7) as a potential lead compound for the NMDA receptor glycine binding site antagonist, starting from readily available 4,5-dichloro-2-nitroaniline(8), is described. The key step in the synthesis involves the cyclization of malonic ester amide 10 to compound 11.

• BMB Reports
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• 제41권4호
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• pp.305-309
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• 2008

Cobalt is an essential microelements in many biological processes involving enzymatic activity. We found that $Zn^{2+}$ and $Mg^{2+}$, which are in the active site of native calf intestine alkaline phosphatase (CIP), can be replaced by $Co^{2+}$ directly in solution. The effect of $Co^{2+}$ concentration on the substitution reaction was examined at ratios of [$Co^{2+}$]/[CIP] from 0:1 to 8:1. The quantity of $Zn^{2+}$ in CIP decreased progressively as the ratio was increased, but the amount of $Mg^{2+}$ changed in irrregular fashion. A series of active site models of the reaction mechanism of CIP are proposed. Low pH was found to promote the replacement of $Mg^{2+}$ by $Co^{2+}$. To understand how the substitution affects the enzyme, we also solved the secondary structure of CIP after reaction with $Co^{2+}$ in different conditions.

• Bulletin of the Korean Chemical Society
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• 제34권1호
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• pp.63-67
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• 2013

A bottom-modified (4-position) naphthalimide derivative 1 with 1,8-naphthyridine as binding site has been designed and synthesized. Compound 1 is the first 1,8-naphthyridine-modified naphthalimide-based sensor that can detect $Hg^{2+}$ selectively with respect to ratiometric fluorescent change and blue shift in organic aqueous solution. The Job's plot and FAB mass indicate that 1 formed a 1:1 complex with $Hg^{2+}$. A top-modified naphthalimide derivative 2 with 1,8-naphthyridin as binding site has also been synthesized for comparison.

• BMB Reports
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• 제51권1호
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• pp.33-38
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• 2018

Sterol regulatory element-binding protein-1c (SREBP1c) plays an important role in triglyceride (TG) homeostasis. Although our previous study showed that hepatitis C virus core-binding protein 6 (HCBP6) regulates SREBP1c expression to maintain intracellular TG homeostasis, the mechanism underlying this regulation is unclear. In the present study, we found that HCBP6 increased intracellular TG levels by upregulating SREBP1c expression. HCBP6 increased SREBP1c transcription by directly binding to the SREBP1c promoter (at the -139- to +359-bp region). Moreover, we observed that HCBP6 interacted with $C/EBP{\beta}-binding$ site in the SREBP1c promoter both in vitro and in vivo. These results indicate that HCBP6 upregulates human SREBP1c expression by binding to the $C/EBP{\beta}-binding$ site in the SREBP1c promoter.

• 의료ㆍ복지 건축 : 한국의료복지건축학회 논문집
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• 제24권2호
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• pp.27-36
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• 2018

Purpose: In the case of mass disaster, the establishment of temporary medical facilities for the first aid and treatment is required for the stable accommodation of patients caused by the disaster. However, the criteria for decision making related to the deployment of field emergency medical facilities are not specified. So, The purpose of this study is to draw considerable factors needed for the deployment of field emergency medical facilities and to make proposal for site selection process of field emergency medical facilities on the basis of the factor. Methods: This study performs text mining of disaster-related laws, guidelines and documents to derive key factors affecting site selection, also proposes a decision making process and conducts virtual deployment to validate the process. Results: The key factors for the site selection derived as the size of the damage, the size of the DMAT inputs, the location of available place, and distance to the disaster base hospital. As a result of virtual deployment following proposed decision making process, It is confirmed that the site of field emergency medical facilities is changed depending on the type of disaster, even if the scope of the disaster damage was the same. Implications: The deployment of field emergency medical facilities requires a separate criteria for each type of disaster, not uniform, as a future research a quantitative approach of the criteria needs to be performed.