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Various Designs of Gluteal Artery Perforator Flap for Buttock Reconstruction (둔부재건을 위한 천공지피판의 다양한 도안)

  • Hong, Seung Eun;Pyon, Jai Kyong
    • Archives of Plastic Surgery
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    • 제34권2호
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    • pp.197-202
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    • 2007
  • Purpose: The gluteal artery perforator flaps earned its popularity in buttock reconstruction due to the lower morbidity of the donor site and the flexibility in the design. Speedy and safe reconstruction is important for the success of buttock reconstruction. If a proper design is selected, satisfactory results can be obtained with more simple method of surgery. Methods: Between April 2005 and April 2006, buttock reconstruction by using gluteal artery perforator flaps were performed on sacral sores(6 cases), ischial sores(2 cases) and malignant melanoma on buttock(1 case). Various designs depending on the location and the size of the defect was made. In those designs, perforator was used as an axis for the minimal dissection of the vessel. Donor site from which sufficient amount of soft tissue can be transferred was selected, and also not causing high tension against the recipient site during the donor site closure. In addition, postoperative aesthetics, and the possibility of another design of a second operation which can be necessary in the future, was considered. Results: Patient follow up was for a mean period of 10.8 months. All flaps survived except for one that had undergone partial necrosis. Wound dehiscence was observed in one patient treated by secondary closure. Most patients presented with cosmetically and functionally satisfying results Conclusion: By designing the flap using the perforator as an axis, depending on the defect size and degree, reconstruction can be performed with only a small tension to the donor and the recipient site. And the minimal perforator dissection allowed easier and faster reconstruction. Selection of a proper design is the key procedure which greatly affects operation time and result success.

The Status and Prospect of Decommissioning Technology Development at KAERI (한국원자력연구원의 해체기술 개발 현황 및 향후 전망)

  • Moon, Jeikwon;Kim, Seonbyung;Choi, Wangkyu;Choi, Byungseon;Chung, Dongyong;Seo, Bumkyoung
    • Journal of Nuclear Fuel Cycle and Waste Technology(JNFCWT)
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    • 제17권2호
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    • pp.139-165
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    • 2019
  • The current status and prospect of decommissioning technology development at KAERI are reviewed here. Specifically, this review focuses on four key technologies: decontamination, remote dismantling, decommissioning waste treatments, and site remediation. The decontamination technologies described are component decontamination and system decontamination. A cutting method and a remote handling method together with a decommissioning simulation are described as remote dismantling technologies. Although there are various types of radioactive waste generated by decommissioning activities, this review focuses on the major types of waste, such as metal waste, concrete waste, and soil waste together with certain special types, such as high-level and high-salt liquid waste, organic mixed waste, and uranium complex waste, which are known to be difficult to treat. Finally, in a site remediation technology review, a measurement and safety evaluation related to site reuse and a site remediation technique are described.

An Analysis of the Moderating Effects of User Ability on the Acceptance of an Internet Shopping Mall (인터넷 쇼핑몰 수용에 있어 사용자 능력의 조절효과 분석)

  • Suh, Kun-Soo
    • Asia pacific journal of information systems
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    • 제18권4호
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    • pp.27-55
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    • 2008
  • Due to the increasing and intensifying competition in the Internet shopping market, it has been recognized as very important to develop an effective policy and strategy for acquiring loyal customers. For this reason, web site designers need to know if a new Internet shopping mall(ISM) will be accepted. Researchers have been working on identifying factors for explaining and predicting user acceptance of an ISM. Some studies, however, revealed inconsistent findings on the antecedents of user acceptance of a website. Lack of consideration for individual differences in user ability is believed to be one of the key reasons for the mixed findings. The elaboration likelihood model (ELM) and several studies have suggested that individual differences in ability plays an moderating role on the relationship between the antecedents and user acceptance. Despite the critical role of user ability, little research has examined the role of user ability in the Internet shopping mall context. The purpose of this study is to develop a user acceptance model that consider the moderating role of user ability in the context of Internet shopping. This study was initiated to see the ability of the technology acceptance model(TAM) to explain the acceptance of a specific ISM. According to TAM. which is one of the most influential models for explaining user acceptance of IT, an intention to use IT is determined by usefulness and ease of use. Given that interaction between user and website takes place through web interface, the decisions to accept and continue using an ISM depend on these beliefs. However, TAM neglects to consider the fact that many users would not stick to an ISM until they trust it although they may think it useful and easy to use. The importance of trust for user acceptance of ISM has been raised by the relational views. The relational view emphasizes the trust-building process between the user and ISM, and user's trust on the website is a major determinant of user acceptance. The proposed model extends and integrates the TAM and relational views on user acceptance of ISM by incorporating usefulness, ease of use, and trust. User acceptance is defined as a user's intention to reuse a specific ISM. And user ability is introduced into the model as moderating variable. Here, the user ability is defined as a degree of experiences, knowledge and skills regarding Internet shopping sites. The research model proposes that the ease of use, usefulness and trust of ISM are key determinants of user acceptance. In addition, this paper hypothesizes that the effects of the antecedents(i.e., ease of use, usefulness, and trust) on user acceptance may differ among users. In particular, this paper proposes a moderating effect of a user's ability on the relationship between antecedents with user's intention to reuse. The research model with eleven hypotheses was derived and tested through a survey that involved 470 university students. For each research variable, this paper used measurement items recognized for reliability and widely used in previous research. We slightly modified some items proper to the research context. The reliability and validity of the research variables were tested using the Crobnach's alpha and internal consistency reliability (ICR) values, standard factor loadings of the confirmative factor analysis, and average variance extracted (AVE) values. A LISREL method was used to test the suitability of the research model and its relating six hypotheses. Key findings of the results are summarized in the following. First, TAM's two constructs, ease of use and usefulness directly affect user acceptance. In addition, ease of use indirectly influences user acceptance by affecting trust. This implies that users tend to trust a shopping site and visit repeatedly when they perceive a specific ISM easy to use. Accordingly, designing a shopping site that allows users to navigate with heuristic and minimal clicks for finding information and products within the site is important for improving the site's trust and acceptance. Usefulness, however, was not found to influence trust. Second, among the three belief constructs(ease of use, usefulness, and trust), trust was empirically supported as the most important determinants of user acceptance. This implies that users require trustworthiness from an Internet shopping site to be repeat visitors of an ISM. Providing a sense of safety and eliminating the anxiety of online shoppers in relation to privacy, security, delivery, and product returns are critically important conditions for acquiring repeat visitors. Hence, in addition to usefulness and ease of use as in TAM, trust should be a fundamental determinants of user acceptance in the context of internet shopping. Third, the user's ability on using an Internet shopping site played a moderating role. For users with low ability, ease of use was found to be a more important factors in deciding to reuse the shopping mall, whereas usefulness and trust had more effects on users with high ability. Applying the EML theory to these findings, we can suggest that experienced and knowledgeable ISM users tend to elaborate on such usefulness aspects as efficient and effective shopping performance and trust factors as ability, benevolence, integrity, and predictability of a shopping site before they become repeat visitors of the site. In contrast, novice users tend to rely on the low elaborating features, such as the perceived ease of use. The existence of moderating effects suggests the fact that different individuals evaluate an ISM from different perspectives. The expert users are more interested in the outcome of the visit(usefulness) and trustworthiness(trust) than those novice visitors. The latter evaluate the ISM in a more superficial manner focusing on the novelty of the site and on other instrumental beliefs(ease of use). This is consistent with the insights proposed by the Heuristic-Systematic model. According to the Heuristic-Systematic model. a users act on the principle of minimum effort. Thus, the user considers an ISM heuristically, focusing on those aspects that are easy to process and evaluate(ease of use). When the user has sufficient experience and skills, the user will change to systematic processing, where they will evaluate more complex aspects of the site(its usefulness and trustworthiness). This implies that an ISM has to provide a minimum level of ease of use to make it possible for a user to evaluate its usefulness and trustworthiness. Ease of use is a necessary but not sufficient condition for the acceptance and use of an ISM. Overall, the empirical results generally support the proposed model and identify the moderating effect of the effects of user ability. More detailed interpretations and implications of the findings are discussed. The limitations of this study are also discussed to provide directions for future research.

Synthesis and Biological Evaluation of N-(Aminopyridine) Benzamide Analogues as Histone Deacetylase Inhibitors

  • Zhang, Qing-Wei;Li, Jian-Qi
    • Bulletin of the Korean Chemical Society
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    • 제33권2호
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    • pp.535-540
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    • 2012
  • A series of benzamide-based histone deacetylases (HDACs) inhibitors possessing N-(aminopyridine) residue as the zinc binding site of HDAC were synthesized and evaluated. Among these derivatives, compounds with N-(2-amino-4-pyridine) benzamide moiety have been found as the most potent ones. Moreover, introduction of appropriate substituents on the terminal aryl group acting as the surface-recognition domain could significantly improve the antiproliferative activity. In particular, the compound 4k possessed favorable pharmacokinetic characteristics and exhibited potent antitumor activity on xenograft model in mice at well tolerated doses, thus suggesting a good therapeutic index.

A Dynamic Analysis on Value Chain Model of E-Commerce - The Case of Online Book Market - (전자상거래의 가치사슬모형에 관한 동태적 분석 - 온라인 서점시장을 중심으로 -)

  • Lee Young-Chan;Seo Chang-Gab
    • Proceedings of the Korea Association of Information Systems Conference
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    • 한국정보시스템학회 2004년도 춘계학술대회
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    • pp.316-335
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    • 2004
  • This paper builds a system dynamics model analyzing first mover effect and growth strategy of online retailer, a major segment of B2C e-commerce. The dynamic model in this paper is calibrated to the online book market and Yes24.com as major test cases. The model consists of eight key value chain sectors. Five of these(Users, Site Operations, Human Resources, Financial Accounting, and Fundraising) are internal to the company, and three others(Market, Financial Market, and Relative Performance) are external to the company. With the model, this paper suggests research propositions representing positive feedback loops and negative feedback loops that lead to corporate growth and limits to growth according to dynamic causal relationships among eight key value chain sectors, and simulate these propositions.

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Elastic Property Extraction System of Polycrystalline Thin-Films for Micro-Electro-Mechanical System Device and Its Applications (MEMS 부품을 위한 다결정 박막의 탄성 물성치 추출 시스템과 적용)

  • Jung Hyang Nam;Choi Jae Hwan;Chung Hee Taeg;Lee June Key
    • Journal of the Korean Society for Precision Engineering
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    • 제22권12호
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    • pp.170-174
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    • 2005
  • A numerical system to extract effective elastic properties of polycrystalline thin-films for MEMS devices is developed. In this system, the statistical model based on lattice system is used for modeling the microstructure evolution simulation and the key kinetics parameters of given micrograph, grain distributions and deposition process can be extracted by inverse method proposed in the system. In this work, effects of kinetics parameters on the extraction of effective elastic properties of polycrystalline thin-films are studied by using statistical method. Effects of the fraction of the potential site($f_p$) among the parameters for deposition process of microstructure on the extraction of effective elastic properties of polycrystalline thin-films are investigated. For this research, polysilicon is applied to this system as the polycrystalline thin-films.

Stability Analysis of Discontinuous Rock by the Block Theory (블록이론에 의한 불연속성 암반내 터널의 안정성 해석)

  • 양형식
    • Tunnel and Underground Space
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    • 제1권
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    • pp.66-74
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    • 1991
  • The block theory with stereographic projection was applied and analyzed on the tunnel section of Samcheok Coal Mine. The results were as follows ; 1) Prevail orientations of discontinuity of sandstone around the main driftway of Samcheok Coal Mine were $(327^{\circ},\;44^{\circ}),\;(13^{\circ},\;24^{\circ}),\;(204^{\circ},\;65^{\circ})$ and $(225^{\circ},\;77^{\circ})$ in dip and dip direction, respectively. 2) Movable blocks of the site were 0110, 0111, 1110(roof), 0100, 0110, 1110(right wall) and 0001, 1001, 1011(left wall). Because of the direction of tunnel, blocks of the left wall was safe. thus key blocks were those of the roof and the right wall. Maximum height of key block was larger than the width of the tunnel but 2m of the yielded zone is expected in general for 5m width tunnel. 3) It is shown that block theory is applicable to large cavern in hard rock analysis.

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Key Methodologies to Effective Site-specific Accessment in Contaminated Soils : A Review (오염토양의 효과적 현장조사에 대한 주요 방법론의 검토)

  • Chung, Doug-Young
    • Korean Journal of Soil Science and Fertilizer
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    • 제32권4호
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    • pp.383-397
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    • 1999
  • For sites to be investigated, the results of such an investigation can be used in determining foals for cleanup, quantifying risks, determining acceptable and unacceptable risk, and developing cleanup plans t hat do not cause unnecessary delays in the redevelopment and reuse of the property. To do this, it is essential that an appropriately detailed study of the site be performed to identify the cause, nature, and extent of contamination and the possible threats to the environment or to any people living or working nearby through the analysis of samples of soil and soil gas, groundwater, surface water, and sediment. The migration pathways of contaminants also are examined during this phase. Key aspects of cost-effective site assessment to help standardize and accelerate the evaluation of contaminated soils at sites are to provide a simple step-by-step methodology for environmental science/engineering professionals to calculate risk-based, site-specific soil levels for contaminants in soil. Its use may significantly reduce the time it takes to complete soil investigations and cleanup actions at some sites, as well as improve the consistency of these actions across the nation. To achieve the effective site assessment, it requires the criteria for choosing the type of standard and setting the magnitude of the standard come from different sources, depending on many factors including the nature of the contamination. A general scheme for site-specific assessment consists of sequential Phase I, II, and III, which is defined by workplan and soil screening levels. Phase I are conducted to identify and confirm a site's recognized environmental conditions resulting from past actions. If a Phase 1 identifies potential hazardous substances, a Phase II is usually conducted to confirm the absence, or presence and extent, of contamination. Phase II involve the collection and analysis of samples. And Phase III is to remediate the contaminated soils determined by Phase I and Phase II. However, important factors in determining whether a assessment standard is site-specific and suitable are (1) the spatial extent of the sampling and the size of the sample area; (2) the number of samples taken: (3) the strategy of taking samples: and (4) the way the data are analyzed. Although selected methods are recommended, application of quantitative methods is directed by users having prior training or experience for the dynamic site investigation process.

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Development of seismic collapse capacity spectra for structures with deteriorating properties

  • Shu, Zhan;Li, Shuang;Gao, Mengmeng;Yuan, Zhenwei
    • Earthquakes and Structures
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    • 제12권3호
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    • pp.297-307
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    • 2017
  • Evaluation on the sidesway seismic collapse capacity of the widely used low- and medium-height structures is meaningful. These structures with such type of collapse are recognized that behave as inelastic deteriorating single-degree-of-freedom (SDOF) systems. To incorporate the deteriorating effects, the hysteretic loop of the nonlinear SDOF structural model is represented by a tri-linear force-displacement relationship. The concept of collapse capacity spectra are adopted, where the incremental dynamic analysis is performed to check the collapse point and a normalized ground motion intensity measure corresponding to the collapse point is used to define the collapse capacity. With a large amount of earthquake ground motions, a systematic parameter study, i.e., the influences of various ground motion parameters (site condition, magnitude, distance to rupture, and near-fault effect) as well as various structural parameters (damping, ductility, degrading stiffness, pinching behavior, accumulated damage, unloading stiffness, and P-delta effect) on the structural collapse capacity has been performed. The analytical formulas for the collapse capacity spectra considering above influences have been presented so as to quickly predict the structural collapse capacities.

KEY R&D ACTIVITIES SUPPORTING DISPOSAL OF RADIOACTIVE WASTE: RESPONDING TO THE CHALLENGES OF THE 21ST CENTURY

  • Miyamoto, Yoichi;Umeki, Hiroyuki;Ohsawa, Hideaki;Naito, Morimasa;Nakano, Katsushi;Makino, Hitoshi;Shimizu, Kazuhiko;Seo, Toshihiro
    • Nuclear Engineering and Technology
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    • 제38권6호
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    • pp.505-534
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    • 2006
  • Ensuring sufficient supplies of clean, economic and acceptable energy is a critical global challenge for the 21st century. There seems little alternative to a greatly expanded role for nuclear power, but implementation of this option will depend on ensuring that all resulting wastes can be disposed of safely. Although there is a consensus on the fundamental feasibility of such disposal by experts in the field, concepts have to be developed to make them more practical to implement and, in particular, more acceptable to key stakeholders. By considering global trends and using illustrative examples from Japan, key areas for future R&D are identified and potential areas where the synergies of international collaboration would be beneficial are highlighted.