• Journal of Life Science
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• v.32 no.9
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• pp.712-720
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• 2022

The purpose of this study was to investigate the efficacy of rat corneal-derived epithelial cells as an in vitro model to evaluate the harmfulness of the cornea caused by particulate matter 2.5 (PM_2.5). To establish an experimental model for the effect of PM_2.5 on corneal epithelial cells, it was confirmed that primary cultured cells isolated from rat eyes were corneal epithelial cells through pan-cytokeratin staining. Our results showed that PM_2.5 treatment reduced cell viability of primary rat corneal epithelial (RCE) cells, which was associated with the induction of apoptosis. PM_2.5 treatment also increased the generation of reactive oxygen species due to mitochondrial dysfunction. In addition, the production of nitric oxide and inflammatory cytokines was increased in PM_2.5-treated RCE cells. Furthermore, through heatmap analysis showing various expression profiling between PM_2.5-exposed and unexposed RCE cells, we proposed five genes, including BLNK, IL-1RA, Itga2b, ABCb1a and Ptgs2, as potential targets for clinical treatment of PM-related ocular diseases. These findings indicate that the primary RCE cell line is a useful in vitro model system for the study of PM_2.5-mediated pathological mechanisms and that PM2.5-induced oxidative and inflammatory responses are key factors in PM2.5-induced ocular surface disorders.

• Journal of Internet Computing and Services
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• v.24 no.1
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• pp.71-86
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• 2023

The purpose of this exploratory study is to compare the differences in public perceptual characteristics of Korean and Chinese societies regarding the metaverse using big data analysis. Due to the environmental impact of the COVID-19 pandemic, technological progress, and the expansion of new consumer bases such as generation Z and Alpha, the world's interest in the metaverse is drawing attention, and related academic studies have been also in full swing from 2021. In particular, Korea and China have emerged as major leading countries in the metaverse industry. It is a timely research question to discover the difference in social awareness using big data accumulated in both countries at a time when the amount of mentions on the metaverse has skyrocketed. The analysis technique identifies the importance of key words by analyzing word frequency, N-gram, and TF-IDF of clean data through text mining analysis, and analyzes the density and centrality of semantic networks to determine the strength of connection between words and their semantic relevance. Python 3.9 Anaconda data science platform 3 and Textom 6 versions were used, and UCINET 6.759 analysis and visualization were performed for semantic network analysis and structural CONCOR analysis. As a result, four blocks, each of which are similar word groups, were driven. These blocks represent different perspectives that reflect the types of social perceptions of the metaverse in both countries. Studies on the metaverse are increasing, but studies on comparative research approaches between countries from a cross-cultural aspect have not yet been conducted. At this point, as a preceding study, this study will be able to provide theoretical grounds and meaningful insights to future studies.

• Biomolecules & Therapeutics
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• v.31 no.1
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• pp.97-107
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• 2023

Aristolochic acid (AA), extracted from Aristolochiaceae plants, plays an essential role in traditional herbal medicines and is used for different diseases. However, AA has been found to be nephrotoxic and is known to cause aristolochic acid nephropathy (AAN). AA-induced acute kidney injury (AKI) is a syndrome in AAN with a high morbidity that manifests mitochondrial damage as a key part of its pathological progression. Melatonin primarily serves as a mitochondria-targeted antioxidant. However, its mitochondrial protective role in AA-induced AKI is barely reported. In this study, mice were administrated 2.5 mg/kg AA to induce AKI. Melatonin reduced the increase in Upro and Scr and attenuated the necrosis and atrophy of renal proximal tubules in mice exposed to AA. Melatonin suppressed ROS generation, MDA levels and iNOS expression and increased SOD activities in vivo and in vitro. Intriguingly, the in vivo study revealed that melatonin decreased mitochondrial fragmentation in renal proximal tubular cells and increased ATP levels in kidney tissues in response to AA. In vitro, melatonin restored the mitochondrial membrane potential (MMP) in NRK-52E and HK-2 cells and led to an elevation in ATP levels. Confocal immunofluorescence data showed that puncta containing Mito-tracker and GFP-LC3A/B were reduced, thereby impeding the mitophagy of tubular epithelial cells. Furthermore, melatonin decreased LC3A/B-II expression and increased p62 expression. The apoptosis of tubular epithelial cells induced by AA was decreased. Therefore, our findings revealed that melatonin could prevent AA-induced AKI by attenuating mitochondrial damage, which may provide a potential therapeutic method for renal AA toxicity.

• Korean Journal of Communication Studies
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• v.17 no.1
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• pp.129-151
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• 2009

Human communication researchers have suggested that good communication between husbands and wives is a key to a healthy marriage. Although interpersonal communication itself cannot "fix" all problems in one's marriage, the importance of good communication in a marital-relationship cannot be overstated. Regardless of its importance, the communication behavior between husbands and wives as a research topic has been paid little attention by human communication scholars in Korea. Because of the "intimacy" Korean couples who have been influenced with the long tradition of Confucius culture tend to overlook the communicative problems in a marital-relationship. Yet, it is "the belief" of the intimacy that creates much of the communicative problems in a marriage. This study is designed to explore the characteristics and transitional process of the communication behavior between Korean husbands and wives among generations. Married couples in their 20's, 30's, 40's, and 50's were surveyed with five levels of interpersonal communication process-open attitudes, problem-solving, expression, listening, and feedback. The study result reveals each generation's characteristics and transitional process of marital communication behavior from younger couples to older couples as their intimacy and "shared" lived-experience get accumulated.

• Korean Chemical Engineering Research
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• v.61 no.2
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• pp.175-188
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• 2023

Global interest in hydrogen energy is increasing as an eco-friendly future energy that can replace fossil fuels. Accordingly, a next-generation hydrogen production technology using microorganisms, nuclear power, etc. is being developed, while a lot of time and effort are still required to overcome the cost of hydrogen production based on fossil fuels. As a way to minimize greenhouse gas emissions in the hydrocarbon-based hydrogen production process, methane direct decomposition technology has recently attracted attention. In order to improve the economic feasibility of the process, the simultaneous production of value-added carbon materials with hydrogen can be one of the most essential aspects. For that purpose, various studies on catalysis related to the quality and yield of high-value carbon materials such as carbon nanotubes (CNTs). In terms of process technology, a number of the research and development of fluidized-bed reactors capable of continuous production and improved gas-solid contact efficiency has been attempted. Recently, methane direct decomposition technology using a fluidized bed has been developed to the extent that it can produce 270 kg/day of hydrogen and 1000 kg/day of carbon. Plus, with the development of catalyst regeneration, separation and recirculation technologies, the process efficiency can be further improved. This review paper investigates the recent development of catalysts and fluidized bed reactor for methane direct pyrolysis to identify the key challenges and opportunities.

• KSCE Journal of Civil and Environmental Engineering Research
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• v.28 no.1D
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• pp.129-136
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• 2008

Along with the development in cutting-edge digital technology, the street space is also being changed. Mobile telecommunication units and internet give a big change in a human being's lifestyle. And the ubiquitous computing is proceeding with expanding its application range from the indoor space to the street space. As the street furniture is the convenient facility that allows a human being's life in street space to be abundant, it is getting advanced. First of all, in terms of such phenomenon, this study analyzed the cases of a research on application of street space and the actual condition of a change in the number of individuals for the street furniture, through a literature research of ubiquitous. Also, it researched into the realities of using the street furniture of the walking-desired streets at Daehac-ro and Hongdae district, where are two representative places related to digital generation. The next was carried out FGI (Focus Group Interview) with users of the street space in front of Hongik University and managers of the street furniture, and was researched into the use & management behavior, and recognition level on the street furniture. Thus, the key elements were extracted such as interchange of information for cultural activities, automation for interaction variability in function. Finally the core elements for future vision of street furniture in this digital era were extracted in 3I, namely, Information, Intellectualization, and Integration. This is considered to be applied to the establishment of direction in the process of high-tech digitalization in street furniture related to information hereafter.

• Journal of the Daesoon Academy of Sciences
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• v.18
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• pp.53-79
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• 2004

This paper explores the relationship between Korean immigrants to the United States and their religious identity from the cultural point of view. Most scholarly studies on Korean immigrants in the United States have been dominated by sociological approach and ethnic studies in examining the social dimension of the Korean immigrant communities while neglecting issues concerning their religious identity and cultural heritage. Most Korean immigrants to America attend Korean churches regardless their religious affiliation before they came to America. One of the reasons for this phenomenon is the fact that Korean church has provided a necessary social service for the newly arrived immigrants. Korean churches have been able to play a key role in the life of Korean immigrants. Korean immigrants, however, have shown a unique aspect regarding their religious identity compared to other immigrants communities in the United States. America is a nation of immigrants, coming from different parts of the world. Each immigrant community has brought their unique cultural heritage and religious persuasion. Asian immigrants, for example, brought their own traditional religions such as Hinduism, Buddhism. People from the Middle Eastern countries brought Islamic faith while European Jews brought the Jewish tradition. In these immigrant communities, religious identity and cultural heritage were homo genously harmonized. Jewish people built synagogue and taught Hebrew, Jewish history, culture, and faith. In this case, synagogue was not only the house of worship for Jews but also the center for learning Jewish history, culture, faith, and language. In short, Jewish cultural history was intimately related to Jewish religious history; for Jewish immigrants, learning their social and political history was indeed identical with leaning of their religious history. The same can be said about the relationship between Indian community and Hinduism. Hindu temples serve as the center of Indian immigrantsin providing the social, cultural, and spiritual functions. Buddhist temples, for that matter, serve the same function to the people from the Asian countries. Chinese, Japanese, Vietnamese, Tibetans, and Thais have brought their respective Buddhist traditions to America and practice and maintain both their religious faith and cultural heritage. Middle Eastern people, for example, have brought Islamic faith to the United States, and Mosques have become the center for learning their language, practicing their faith, and maintaining their cultural heritage. Korean immigrants, unlike any other immigrant group, have brought Christianity, which is not a Korean traditional religion but a Western religion they received in 18th and 19th centuries from the West and America, back to the United States, and church has become the center of their lives in America. In this context, Koreans and Korean-Americans have a unique situation in which they practice Christianity as their religion but try to maintain their non-Christian cultural heritage. For the Korean immigrants, their religious identity and cultural identity are not the same. Although Korean church so far has provides the social and religious functions to fill the need of Korean immigrants, but it may not be able to become the most effective institution to provide and maintain Korean cultural heritage. In this respect, Korean churches must be able to open to traditional Korean religions or the religions of Korean origin to cultivate and nurture Korean cultural heritage.

• Journal of the Korean Society of Marine Environment & Safety
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• v.29 no.7
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• pp.724-739
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• 2023

Located in the sea area between South Korea, North Korea, and China, the Yellow Sea plays an important role from a geopolitical perspective, and recently, as the use of marine space in the Yellow Sea is expanding, its social and economic values have been increasing further. In addition, owing to rapid climate changes, the need for joint response and cooperation between Korea and China is increasing in various fields, including changes in the marine environment and marine ecosystem and generation and movement of air pollutants. Accordingly, in this study, core topics were derived from research papers with the Yellow Sea as a keyword, and research trends to date were explored through author network analysis. As a specific research method, research papers related to the Yellow Sea published between 1984 and 2021 were extracted from the Web of Science database and were classified into four periods to derive core topics using topic modeling, a type of text mining. Furthermore, the influences of major research communities, researchers, and research institutes in the appropriate fields were identified through analyzing the author network, and their implications were presented. The analysis results indicated that the core topics of research papers on the Yellow Sea had changed over time, and differences existed in the influence (centrality) of key researchers. Finally, based on the results of this study, this study aims to identify research trends related to the Yellow Sea, major researchers, and research institutes and contribute to research cooperation between Korea and China regarding the Yellow Sea in the future.

• Korean Chemical Engineering Research
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• v.61 no.4
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• pp.496-504
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• 2023

Countries worldwide are striving to find new sources of sustainable energy without carbon emission due to the increasing impact of global warming. With the advancement of the fourth industrial revolution on a global scale, there has been a substantial rise in energy demand. Simultaneously, there is a growing emphasis on utilizing energy sources with minimal or zero carbon content to ensure a stable power supply while reducing greenhouse gas emissions. In this comprehensive overview, a comparative analysis of carbon reduction policies of government was conducted. Based on international carbon neutrality scenarios and the presence of remaining thermal power generation, it can be categorized into two types: "Rapid" and "Safety". For the domestic scenario, the projected power demand and current greenhouse gas emissions in alignment with "The 10th Basic Plan for Electricity Supply and Demand" was examined. Considering all these factors, an overview of the current status of carbon neutrality technologies by focusing on the energy sector, encompassing transitions, hydrogen, transportation and carbon capture, utilization, and storage (CCUS) was offered followed by summarization of key technological trends and government-driven policies. Furthermore, the central aspects of the domestic carbon reduction strategy were proposed by taking account of current mega trends in the energy sector which are highlighted in international scenario analyses.

• Journal of the Korean institute of surface engineering
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• v.56 no.6
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• pp.412-419
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• 2023

Anion exchange membrane electrolysis is considered a promising next-generation hydrogen production technology that can produce low-cost, clean hydrogen. However, anion exchange membrane electrolysis technology is in its early stages of development and requires intensive research on electrodes, which are a key component of the catalyst-system interface. In this study, we optimized the pressure conditions of the hot-pressing process to manufacture cobalt oxide electrodes for the development of a high uniformity and high adhesion electrode production process for the oxygen evolution reaction. As the pressure increased, the reduction of pores within the electrode and increased densification of catalytic particles led to the formation of a uniform electrode surface. The cobalt oxide electrode optimized for pressure conditions exhibited improved catalytic activity and durability. The optimized electrode was used as the anode in an AEMWE single cell, exhibiting a current density of 1.53 A cm^-2 at a cell voltage of 1.85 V. In a durability test conducted for 100 h at a constant current density of 500 mA cm^-2, it demonstrated excellent durability with a low degradation rate of 15.9 mV kh^-1, maintaining 99% of its initial performance.