• Title/Summary/Keyword: Key Exposure

Search Result 445, Processing Time 0.028 seconds

Exposure Concentration of Tetrabromobisphenol A in Southwestern Coast and Their Photodecomposition Characteristics (서남해연안해역에서 Tetrabromobisphenol A의 노출농도 및 그들의 광화학적 분해 특성)

  • Han, Sang-Kuk
    • Journal of Environmental Science International
    • /
    • v.25 no.3
    • /
    • pp.373-383
    • /
    • 2016
  • The aim of this study is to determine the exposure concentration of tetrabromobisphenol A(TBBPA) in southwestern coast and their photodecomposition rate. Also, it is to identify the radical species of the photodecomposition of TBBPA and their reactive byproducts using the electron spin resonance(ESR) method. TBBPA was not detected in any of the sea water samples from Mokpo, Gunsan, or Goheung. The sediment samples from Mokpo contained not detection(N.D)~50.0 ng/g dry wt., while those from Gunsan contained N.D~28.5 ng/g dry wt. and those from Goheung contained N.D~7.3 ng/g dry wt. The photodecomposition rates were $2.56{\times}10^{-6}/hr$ by visible light(400 nm), $7.98{\times}10^{-6}/hr$ by ultraviolet light(300 nm <), and $6.78{\times}10^{-6}/hr$ by sunlight. Also, we confirmed that singlet oxygen and hydroxyl radicals are the key reactive oxygen species at wavelengths greater than 400 and 300 nm, respectively. This study shows that the main byproducts formed during irradiation at wavelengths above 300 nm are 2,6-dibromobenzosemiquinone radical(2,6-$DBSQ{\cdot}^-$) and g-value 2.0048 doublet spectrum.

Toxicity and Carcinogenicity of Dichlorodiphenyltrichloroethane (DDT)

  • Harada, Takanori;Takeda, Makio;Kojima, Sayuri;Tomiyama, Naruto
    • Toxicological Research
    • /
    • v.32 no.1
    • /
    • pp.21-33
    • /
    • 2016
  • Dichlorodiphenyltrichloroethane (DDT) is still used in certain areas of tropics and subtropics to control malaria and other insect-transmitted diseases. DDT and its metabolites have been extensively studied for their toxicity and carcinogenicity in animals and humans and shown to have an endocrine disrupting potential affecting reproductive system although the effects may vary among animal species in correlation with exposure levels. Epidemiologic studies revealed either positive or negative associations between exposure to DDT and tumor development, but there has been no clear evidence that DDT causes cancer in humans. In experimental animals, tumor induction by DDT has been shown in the liver, lung, and adrenals. The mechanisms of hepatic tumor development by DDT have been studied in rats and mice. DDT is known as a non-genotoxic hepatocarcinogen and has been shown to induce microsomal enzymes through activation of constitutive androstane receptor (CAR) and to inhibit gap junctional intercellular communication (GJIC) in the rodent liver. The results from our previously conducted 4-week and 2-year feeding studies of p,p'-DDT in F344 rats indicate that DDT may induce hepatocellular eosinophilic foci as a result of oxidative DNA damage and leads them to hepatic neoplasia in combination with its mitogenic activity and inhibitory effect on GJIC. Oxidative stress could be a key factor in hepatocarcinogenesis by DDT.

Potential Health Risks from Persistent Organic Pollutants (POPs) in Marine Ecosystem

  • Lee, Youn Ju;Jang, Jae-Seok;Yang, Jae-Ho
    • Journal of Marine Bioscience and Biotechnology
    • /
    • v.8 no.1
    • /
    • pp.10-17
    • /
    • 2016
  • A wide-spread contamination of persistent organic pollutants (POPs) such as dioxins, PCBs, PBDEs in the aquatic ecosystem has generated a great concern over the potential risk for these substances to impact marine biotas and food web. Since a major exposure route of these substances to the humans is through the consumption of food including fish and marine byproducts, the consumption of contaminated products has been a great public health concern. Exposure to POPs has been associated with a wide spectrum of adverse effects including reproductive, developmental, immunologic, carcinogenic, and neurotoxic effects. This review covers the background information of key POPs substances and the recent development of toxicity studies including the mode of action. Because neurotoxic effects of some POPs have been observed in humans at low concentrations, polychlorinated biphenyl (PCB), a representative chemical of POPs, is focused to discuss the possible mode(s) of action for the neurotoxic effects. This review provides the updates of toxicity studies on POPs and paves ways to discuss a possible implication of contaminated marine biota over the human health among the marine biotechnology researchers.

An hygienical study on fomentation wear textile and design

  • Shim, Boo-Ja
    • Journal of Fashion Business
    • /
    • v.9 no.6
    • /
    • pp.101-116
    • /
    • 2005
  • The study with the subjects of the female consumers of the fomentation rooms in their 20s, this research made an investigation of the fomentation wear. Also, dye-fastness experiments of the wear's colors against washing and sweating were held. The following are the conclusions; 1. Survey Results of the Present Situations of Fomentation Wear Designs of the fomentation wear, 88% belonged to a T-shirt (upper clothes) and knee pants. The primary colors of the wear were in the order of gray (37.5%), white (31.3%), orange (25%), indigo (18.8%), and yellowish (18.8%). 43% of the wear companies used the same color for two-piece clothes, and 57% employed different colors for upper and lower clothes. 2. Consumers' Attitude about Fomentation Wear The key problem in the attitude to the wear, 25.9% pointed out the worries about physical exposure (like breasts and legs) owing to the improperness in designs and sizes. 32.8% of the subjects were also worried about physical silhouette exposure following sweating. The need for design improvement was felt as the subjects expressed their intention to use better fomentation wear in design and materials if the fare is higher. 3. Experimental Results of the Dye fastness of the Fomentation Wear Dye-fastness experiments by sweating appeared in the order of gray > white > pink. The results by washing were gray & white > pink. As laundry grew in number, the grade of dye fastness fell a little bit. In the fomentation environment with more laundry and more perspiration, dye fastness of the wear's colors against washing and sweating should be fully considered.

The Role of L1 and L2 in an L3-speaking Class

  • Kim, Sun-Young
    • Cross-Cultural Studies
    • /
    • v.24
    • /
    • pp.170-183
    • /
    • 2011
  • This study explored how a Chinese college student who previously had not reached a threshold level of Korean proficiency used L1 (Chinese) and L2 (English) as a tool to socialize into Korean (L3) culture of learning over the course of study. From a perspective of language socialization, this study examined the cross-linguistic influence of L1 and L2 on the L3 acquisition process by tracing an approach to language learning and practices taken by the Chinese student as a case study. Data were collected through three methods; interview protocols, various types of written texts, and observations. The results showed that the student used English as a means to negotiate difficulties and expertise by empowering her L2 exposure during the classroom practices. Her ways of using L2 in oral practices could be characterized as the 'Inverse U-shape' pattern, under which she increased L2 exposure at the early stage of the study and shifted the intermediate language to L3 at the later stage of the study. When it comes to the language use in written practices, the sequence of "L2-L1-L3" use gradually changed to the "L2-L3" sequence over time, signifying the importance of interaction between L2 and L3. However, the use of her native language (L1) in a Korean-speaking classroom was limited to a certain aspect of literacy practices (i.e., vocabulary learning or translation). This study argues for L2 communication channel in cross-cultural classrooms as a key factor to determine sustainable learning growth.

A New Forward-Secure Signature Scheme based on GDH groups (Gap Diffie-Hellman 군에 기반한 전방향 안전성을 갖는 서명 기법)

  • 강보경;박제홍;한상근
    • Journal of the Korea Institute of Information Security & Cryptology
    • /
    • v.13 no.5
    • /
    • pp.147-157
    • /
    • 2003
  • We often use cryptographic systems on small devices such as mobile phones, smart cards and so on. But such devices are delicate against the tlreat of key exposure of secret keys. To reduce the damage caused by exposure of secret keys stored on such devices, the concept of forward security is introduced. In this Paper, we present a new forward secure signature scheme based on Gap Diffie-Hellman groups. Our scheme achieves security against chosen-message attacks under the computational Diffie-Hellman assumption in the random oracle model.

GAN-Based Local Lightness-Aware Enhancement Network for Underexposed Images

  • Chen, Yong;Huang, Meiyong;Liu, Huanlin;Zhang, Jinliang;Shao, Kaixin
    • Journal of Information Processing Systems
    • /
    • v.18 no.4
    • /
    • pp.575-586
    • /
    • 2022
  • Uneven light in real-world causes visual degradation for underexposed regions. For these regions, insufficient consideration during enhancement procedure will result in over-/under-exposure, loss of details and color distortion. Confronting such challenges, an unsupervised low-light image enhancement network is proposed in this paper based on the guidance of the unpaired low-/normal-light images. The key components in our network include super-resolution module (SRM), a GAN-based low-light image enhancement network (LLIEN), and denoising-scaling module (DSM). The SRM improves the resolution of the low-light input images before illumination enhancement. Such design philosophy improves the effectiveness of texture details preservation by operating in high-resolution space. Subsequently, local lightness attention module in LLIEN effectively distinguishes unevenly illuminated areas and puts emphasis on low-light areas, ensuring the spatial consistency of illumination for locally underexposed images. Then, multiple discriminators, i.e., global discriminator, local region discriminator, and color discriminator performs assessment from different perspectives to avoid over-/under-exposure and color distortion, which guides the network to generate images that in line with human aesthetic perception. Finally, the DSM performs noise removal and obtains high-quality enhanced images. Both qualitative and quantitative experiments demonstrate that our approach achieves favorable results, which indicates its superior capacity on illumination and texture details restoration.

PRACTICAL APPROACHES TO RISK MANAGEMENT FOR GLOBAL CONTRACTORS

  • Seung Heon Han;Du Yon Kim;Han Him Kim
    • International conference on construction engineering and project management
    • /
    • 2005.10a
    • /
    • pp.1231-1236
    • /
    • 2005
  • Global construction projects manifest more risks than do other industries. Often, firms doing business in construction markets find these risks intimidating. To secure corresponding profits, many global contractors attempt to forecast the effects of risks and establish risk management strategies. However, one key problem with present-day risk management methods is that they are basically analytical or mathematical-oriented approaches which are not easy to adopt in real business. Based on preliminary investigations and evaluations of current tools, this research elicits more practical algorithms for risk checklist by constructing risk scenarios over the whole period of project execution. For the application of the algorithms, a "SE/RF" (Source-Event/Regular-Floating) checklist is suggested, which sorts out risk sources and their subsequent events, as well as dividing various risk factors into either regular or floating categories. In addition, the "PIS" (Probability-Impact-Significance) method is introduced, in place of traditional "PI" (Probability-Impact) methods, by adding the additional criterion of "risk significance" to determine the degree of risk exposure in a more realistic way. As a result, we draw the significant finding that the "PIS" method presents a closer evaluation regarding degree of risk exposure as compared to the level of expert judgments than those from traditional methods. Finally, we provide an integrated procedure for international project risk management with all of the research achievements being incorporated.

  • PDF

Modeling the Chemical Kinetics of Atmospheric Plasma

  • Kim, Ho-Yeong;Lee, Hyeon-U;Kim, Gyu-Cheon;Lee, Jae-Gu
    • Proceedings of the Korean Vacuum Society Conference
    • /
    • 2012.08a
    • /
    • pp.270-270
    • /
    • 2012
  • Low temperature atmospheric pressure plasmas (APPs) have been known to be effective for living cell inactivation in the water [1]. Many earlier research found that pH level of the solution was changed from neutral to acidic after plasma treatment. The importance of the effect of acidity of the solution for cell treatments has already been reported by many experiments. In addition, several studies have demonstrated that the addition of a small amount of oxygen to pure helium results in higher sterilization efficiency of APPs [2]. However, it is not clear yet which species are key factors for the cell treatment. To find key factors, we used GMoo simulation. We elucidate the processes through which pH level in the solution is changed from neutral to acidic after plasma exposure and key components with pH and air variation with using GMoo simulation. First, pH level in a liquid solution is changed by He+ and He(21S) radicals. Second, O3 density decreases as pH level in the solution decreases and air concentration decreases. It can be a method of removing O3 that cause chest pain and damage lung tissue when the density is very high. H2O2, HO2 and NO radicals are found to be key factors for cell inactivation in the solution with pH and air variation.

  • PDF

Protective Effect of Polysaccharide Fractions from Radix A. Sinensis against tert-Butylhydroperoxide Induced Oxidative Injury in Murine Peritoneal Macrophages

  • Yang, Xingbin;Zhao, Yan;Lv, You;Yang, Ying;Ruan, Yun
    • BMB Reports
    • /
    • v.40 no.6
    • /
    • pp.928-935
    • /
    • 2007
  • Three Angelica sinensis polysaccharide fractions (APFs), named APF1, APF2 and APF3, were isolated and purified from Radix A. sinensis and their antioxidant activities were evaluated in isolated mouse peritoneal macrophages by pretreatment with APFs before exposure to 0.2 mM tertbutylhydroperoxide (t-BHP). The results showed that pretreatment of the macrophages with APFs as low as $10{\mu}g$/ml could significantly enhance t-BHP-decreased cell survival, intracellular glutathione (GSH) content and superoxide dismutase (SOD) activity, and also inhibited t-BHP-increased lactate dehydrogenase (LDH) leakage and malondialdehyde (MDA) formation (p < 0.05), and APF3 was the most active fraction, followed by APF2 and APF1 in decreasing order. Furthermore, we found for the first time that the bound-protein in APF3 was associated closely with the protective effects and the polysaccharide inhibited the excess NO release from t-BHP-activated macrophages to protect host cells.