• The Journal of Korean Institute of Communications and Information Sciences
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• v.31 no.10C
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• pp.1011-1022
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• 2006

WSN(Wireless Sensor Network) performs to detect and collect environmental information for one purpose. The WSN is composed of a sink node and several sensor nodes and has a constraint in an aspect of energy consumption caused by limited battery resource. So many required mechanisms in WSN should consider the remaining energy condition. To deploy WSN, tile collected information is required to protect from an adversary over the network in many cases. The security mechanism should be provided for collecting the information over the network. we propose asynchronized key management considering energy efficiency over WSN. The proposed key management is focused on independence and difference of the keys used to deliver the information over several routes over the network, so disclosure of any key does not results in exposure of total key information over the overall WSN. Also, we use hash function to update key information for energy efficiency Periodically. We define the insecurity for requested security Properties and Proof that the security properties are guaranteed. Also, we evaluate and analyze the energy efficiency for the proposed mechanism.

• Asian Pacific Journal of Cancer Prevention
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• v.15 no.6
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• pp.2699-2705
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• 2014

This study was to undertaken to investigate the impacts of AhR, CYP1A1, GSTM1 genetic polymorphisms on the R273G mutation in exon 8 of the tumor suppressor p53 gene (TP53) among polycyclic aromatic hydrocarbons (PAHs) exposed to coke-oven workers. One hundred thirteen workers exposed to PAH and 82 control workers were recruited. We genotyped for polymorphisms in the AhR, CYP1A1, GSTM1, and TP53 R273G mutation in blood by PCR methods, and determined the levels of 1-hydroxypyrene as PAH exposure marker in urine using the high pressure liquid chromatography assay. We found that the distribution of alcohol users and the urinary excretion of 1-OHP in the exposed workers were significantly higher than that of the control workers (p=0.004, p<0.001, respectively). Significant differences were observed in the p53 genotype distributions of smoking subjects (p=0.01, 95%CI: 1.23-6.01) and PAH exposure (p=0.008, 95%CI: 1.24-4.48), respectively. Further, significant differences were observed in the p53 exon 8 mutations for the genetic polymorphisms of Lys/Arg for AhR (p=0.02, 95%CI: 0.70-15.86), Val/Val for CYP1A1 (p=0.04, 95%CI: 0.98-19.09) and null for GSTM1 (p=0.02, 95%CI: 1.19-6.26), respectively. Our findings indicated that polymorphisms of PAH metabolic genes, such as AhR, CYP1A1, GSTM1 polymorphisms may interact with p53 genetic variants and may contribute to PAH related cancers.

• Nuclear Engineering and Technology
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• v.53 no.6
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• pp.1942-1946
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• 2021

Gadolinium oxysulfide (GOS) is regarded as a novel scintillator for the realization of ultra-high spatial resolution in neutron imaging. Monte Carlo simulations of GOS scintillator show that the capability of its spatial resolution is towards the micron level. Through the time-of-flight method, the light output of a GOS scintillator was measured to be 217 photons per captured neutron, ~100 times lower than that of a ZnS/LiF:Ag scintillator. A detector prototype has been developed to evaluate the imaging solution with the GOS scintillator by neutron beam tests. The measured spatial resolution is ~36 ㎛ (28 line pairs/mm) at the modulation transfer function (MTF) of 10%, mainly limited by the low experimental collimation ratio of the beamline. The weak light output of the GOS scintillator requires an enormous increase in the neutron flux to reduce the exposure time for practical applications.

• Asian Pacific Journal of Cancer Prevention
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• v.15 no.9
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• pp.3981-3986
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• 2014

Ganoderma lucidum polysaccharides (GLP) extracted from Ganoderma lucidum have been shown to induce cell death in some kinds of cancer cells. This study investigated the cytotoxic and apoptotic effect of GLP on HCT-116 human colon cancer cells and the molecular mechanisms involved. Cell proliferation, cell migration, lactate dehydrogenase (LDH) levels and intracellular free calcium levels ($[Ca^{2+}]i$) were determined by MTT, wound-healing, LDH release and fluorescence assays, respectively. Cell apoptosis was observed by scanning and transmission electron microscopy. For the mechanism studies, caspase-8 activation, and Fas and caspase-3 expression were evaluated. Treatment of HCT-116 cells with various concentrations of GLP (0.625-5 mg/mL) resulted in a significant decrease in cell viability (P< 0.01). This study showed that the antitumor activity of GLP was related to cell migration inhibition, cell morphology changes, intracellular $Ca^{2+}$ elevation and LDH release. Also, increase in the levels of caspase-8 activity was involved in GLP-induced apoptosis. Western blotting indicated that Fas and caspase-3 protein expression was up-regulated after exposure to GLP. This investigation demonstrated for the first time that GLP shows prominent anticancer activities against the HCT-116 human colon cancer cell line through triggering intracellular calcium release and the death receptor pathway.

• Journal of Digital Convergence
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• v.13 no.10
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• pp.343-351
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• 2015

With the diverse services of the current M2M environment being expanded to the organizations, the corporations, and the daily lives, the possibility of the occurrence of the vulnerabilities of the security of the related technologies have become an issue. In order to solve such a problem of the vulnerability of the security, this thesis proposes the technique for applying the cryptography algorithm for the protection of the device key of the M2M environment. The proposed technique was based on the elliptic curve cryptography Through the key exchange and the signature exchange in the beginning, the security session was created. And the white box cipher was applied to the encryption that creates the white box table using the security session key. Application results cipher algorithm, Elliptic Curve Cryptography provides a lightweight mutual authentication, a session key for protecting the communication session and a conventional white-box cipher algorithm and was guaranteed the session key used to encrypt protected in different ways. The proposed protocol has secure advantages against Data modulation and exposure, MITM(Man-in-the-middle attack), Data forgery and Manipulation attack.

• Plant Biotechnology Reports
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• v.4 no.3
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• pp.213-222
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• 2010

Within their natural habitat, crops are often subjected to drought and heat stress, which suppress crop growth and decrease crop production. Causing overaccumulation of glycinebetaine (GB) has been used to enhance the crop yield under stress. Here, we investigated the response of wheat (Triticum aestivum L.) photosynthesis to drought, heat stress and their combination with a transgenic wheat line (T6) overaccumulating GB and its wild-type (WT) Shi4185. Drought stress (DS) was imposed by controlling irrigation until the relative water content (RWC) of the flag leaves decreased to between 78 and 82%. Heat stress (HS) was applied by exposing wheat plants to $40^{\circ}C$ for 4 h. A combination of drought and heat stress was applied by subjecting the drought-stressed plants to a heat stress as above. The results indicated that all stresses decreased photosynthesis, but the combination of drought and heat stress exacerbated the negative effects on photosynthesis more than exposure to drought or heat stress alone. Drought stress decreased the transpiration rate (Tr), stomatal conductance (Gs) and intercellular $CO_2$ concentration (Ci), while heat stress increased all of these; the deprivation of water was greater under drought stress than heat stress, but heat stress decreased the antioxidant enzyme activity to a greater extent. Overaccumulated GB could alleviate the decrease of photosynthesis caused by all stresses tested. These suggest that GB induces an increase of osmotic adjustments for drought tolerance, while its improvement of the antioxidative defense system including antioxidative enzymes and antioxidants may be more important for heat tolerance.

• Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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• 2013.05a
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• pp.856-858
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• 2013

The data which is sensed on USN(Ubiquitous Sensor Network) environment is concerned with personal privacy and the secret information of business, but it has more vulnerable characteristics, in contrast to common networks. In other words, USN has the vulnerabilities which is easily exposed to the attacks such as the eavesdropping of sensor information, the distribution of abnormal packets, the reuse of message, an forgery attack, and denial of service attacks. Therefore, the key is necessarily required for secure communication between sensor nodes. This paper proposes a KDPC(Key Distribution Protocol based on Cluster) using ECDH algorithm by considering the characteristics of sensor network. As a result, the KDPC can provide the safe USN environment by detecting the forgery data and preventing the exposure of sensing data.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.35 no.3B
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• pp.462-473
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• 2010

The RFID system has the security problem of location tracking and user privacy. In order to solve this problem, the cryptographic access method using hash function is difficult to in real applications. Because there is a limit of computing and storage capacity of Tag, but the safety is proved. The lightweight authentication methods like HB and LMAP guarantee the high efficiency, but the safety is not enough to use. In this paper, we use the AES for RFID Authentication, and solve the problem of using fixed key with key change step by step. The symmetric keys of the tag and server are changed by the random number generated by tag, reader and server successively. This could prevent the key exposure. As a result, the output of the tag and reader always changes. These key changes could make it possible to prevent eavesdropping, replay attack, location tracking and spoofing.

• Journal of Microbiology and Biotechnology
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• v.20 no.12
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• pp.1630-1636
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• 2010

During the fermentation process of Saccharomyces cerevisiae, yeast cells must rapidly respond to a wide variety of external stresses in order to survive the constantly changing environment, including ethanol stress. The accumulation of ethanol can severely inhibit cell growth activity and productivity. Thus, the response to changing ethanol concentrations is one of the most important stress reactions in S. cerevisiae and worthy of thorough investigation. Therefore, this study examined the relationship between ethanol tolerance in S. cerevisiae and a unique protein called alcohol sensitive RING/PHD finger 1 protein (Asr1p). A real-time PCR showed that upon exposure to 8% ethanol, the expression of Asr1 was continuously enhanced, reaching a peak 2 h after stimulation. This result was confirmed by monitoring the fluorescence levels using a strain with a green fluorescent protein tagged to the C-terminal of Asr1p. The fluorescent microscopy also revealed a change in the subcellular localization before and after stimulation. Furthermore, the disruption of the Asr1 gene resulted in hypersensitivity on the medium containing ethanol, when compared with the wild-type strain. Thus, when taken together, the present results suggest that Asr1 is involved in the response to ethanol stress in the yeast S. cerevisiae.

• Computers and Concrete
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• v.24 no.3
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• pp.249-258
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• 2019

In order to investigate the strength recovery of fire-damaged concrete after post-fire curing, concrete specimens were heating at $2^{\circ}C/min$ or $5^{\circ}C/min$ to 400, 600 and $800^{\circ}C$, and these exposed specimens were soaked in the water for 24 hours and following by 29-day post-fire curing. The compressive strength and split tensile strength of the high-temperature-exposed specimens before and after post-fire curing were tested. The proportion of split aggregate in the split surfaces was analyzed to evaluate the mortar-aggregate interfacial strength. After the post-fire curing process, the split tensile strength of specimens exposed to all temperatures was recovered significantly, while the recovery of compressive strength was only obvious within the specimens exposed to $600^{\circ}C$. The tensile strength is more sensitive to the mortar-aggregate interfacial cracks, which caused that the split tensile strength decreased more after high-temperature exposure and recovery more after post-fire curing than the compressive strength. The mortar-aggregate interfacial strength also showed remarkable recovery after post-fire curing, and it contributed to the recovery of split tensile strength.