• Korean Chemical Engineering Research
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• v.47 no.6
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• pp.740-746
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• 2009

In the present study, the drowning-out crystallization of L(+)-calcium lactate was investigated in order to develop the crystallization separation process. The crystallization of the calcium lactate was induced by injecting the alcoholic anti-solvent into the aqueous solution of calcium lactate and the control of the calcium lactate crystal size during the crystallization was primarily investigated under the consideration of the anti-solvent species, anti-solvent composition and agitation speed as the key operating factors. Alcohols of methanol, ethanol, n-propanol and i-propanol were used as the anti-solvent for the drowning-out crystallization. Prior to the crystallization experiment, the solubility of calcium lactate in the water-alcohol mixture was measured along with the variation of the alcohol species and composition, which was necessary to estimate the supersaturation level of the crystallization. By the drowning-out crystallization, the calcium lactate crystals of the fabric shape were obtained. Using the ethanol as the antisolvent, the fabric crystals close to the needle shape were produced. However, the hairy crystals were obtained by using the propanol as the anti-solvent. Due to such morphological features, the crystals was highly apt to form the aggregates. The aggregation of the crystals was intensified as increasing the alcohol fraction in the water-alcohol mixture. Meanwhile, the agitation caused the breakage of crystals, resulting in the decrease of the crystal size. Therefore, the crystal size in the crystallization was predominantly determined by the competition between the crystal aggregation and breakage.

• The KIPS Transactions:PartC
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• v.15C no.5
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• pp.329-342
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• 2008

The Sensor Networks have limitations in utilizing energies, developing energy-efficient routing protocol and secure routing protocol are important issues in Sensor Network. In the field of data management, Tributaries and Deltas(TD) which incorporates tree topology and multi-path topology effectively have been suggested to provide efficiency and robustness in data aggregation. And our research rendered hierarchical property to TD and proposed Clustering-based Tributaries-Deltas. Through this new structure, we integrated efficiency and robustness of TD structure and advantages of hierarchical Sensor Network. Clustering-based Tributaries-Deltas was proven to perform better than TD in two situations through our research. The first is when a Base Station (BS) notices received information as wrong and requests the network's sensing data retransmission and aggregation. And the second is when the BS is mobile agent with mobility. In addition, we proposed key establishment mechanism proper for the newly proposed structure which resulted in new Sensor Network structure with improved security and energy efficiency as well. We demonstrated that the new mechanism is more energy-efficient than previous one by analyzing consumed amount of energy, and realized the mechanism on TmoteSKY sensor board using TinyOS 2.0. Through this we proved that the new mechanism could be actually utilized in network design.

• Korean Chemical Engineering Research
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• v.46 no.4
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• pp.756-763
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• 2008

The aim of this work was to obtain uniform and well-dispersed spherical silver nanoparticles using statistical design-of-experiment methods. We performed the experiments using 2 k fractional factorial designs with respect to key factors of a general chemical reduction method. The nanoparticles prepared were characterized by SEM, TEM and UV-visible absorbance for particle size, distribution, aggregation and anisotropy. The data obtained were analyzed and optimized using a statistical software, Minitab. The design-of-experiment methods using quantified data enabled us to determine key factors and appreciate interactions between factors. The measured properties of nanoparticles were dominated not only by individual one or two main factors but also by interactions between factors. The appropriate combination of the factors produced small, narrow-distributed and non-aggregated silver nanoparticles of about 30 nm with approximately 10% standard deviation.

• KSII Transactions on Internet and Information Systems (TIIS)
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• v.9 no.2
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• pp.728-741
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• 2015

Stereo vision has become an important technical issue in the field of 3D imaging, machine vision, robotics, image analysis, and so on. The depth map extraction from stereo video is a key technology of stereoscopic 3D video requiring stereo correspondence algorithms. This is the matching process of the similarity measure for each disparity value, followed by an aggregation and optimization step. Since it requires a lot of computational power, there are significant speed-performance advantages when exploiting parallel processing available on processors. In this situation, multi-core CPU may allow many parallel programming technologies to be realized in users computing devices. This paper proposes parallel implementations for calculating disparity map using a shared memory programming and exploiting the streaming SIMD extension technology. By doing so, we can take advantage both of the hardware and software features of multi-core processor. For the performance evaluation, we implemented a parallel SAD algorithm with OpenMP and SSE2. Their processing speeds are compared with non parallel version on stereoscopic streaming video. The experimental results show that both technologies have a significant effect on the performance and achieve great improvements on processing speed.

• Korean Journal of Pharmacognosy
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• v.37 no.2 s.145
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• pp.97-102
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• 2006

Garlic(Allium sativum Linn) is widely used as a common condiment for a variety of foods and beverages. It has been well known that fresh garlic and garlic supplement of commercial preparations have various therapeutic properties including antimicrobial activity, antiplatelet aggregation, antihypertension, and cholesterol-lowering effects, which contribute to its increasing uses for an alternative medicine. Allicin(diallyl thiosulfinate), the major bioactive components of garlic, is formed by alliinase cleavage of the naturally occurring alliin upon crushing or mincing of garlic, and is the progenitor of a number of other products, such as diallyl disulfide. CYP3A4, heme-containing monooxygenase, is a key enzyme responsible for drug metabolism. Therefor, in the present study, we isolated and examined the compounds with CYP3A4-inhibiting activities from garlic. Among EtOAc extracts of garlic, we found that N-p-coumaroyltyramine and N-feruloyltyramine showed remarkable CYP3A4-inhibiting activities, compared to diallyl disulfide. Structures of the isolated active compounds were established by chemical and spectroscopic means.

• Fisheries and Aquatic Sciences
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• v.21 no.5
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• pp.13.1-13.8
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• 2018

Amyloid plaque, also called senile plaque, the product of aggregation of ${\beta}$-amyloid peptides ($A{\beta}$), is observed in brains of the patients with Alzheimer's disease (AD) and is one of the key factors in etiology of the disease. In this study, hydrolysates obtained from the sea hare (Aplysia kurodai) were investigated for ${\beta}$-secretase inhibitory peptide. The sea hare's muscle protein was hydrolyzed using six enzymes in a batch reactor. Trypsin hydrolysate had highest ${\beta}$-secretase inhibitory activity compared to the other hydrolysates. ${\beta}$-secretase inhibitory peptide was separated using Sephadex G-25 column chromatography and high-performance liquid chromatography on a C18 column. ${\beta}$-secretase inhibitory peptide was identified as eight amino acid residues of Val-Ala-Ala-Leu-Met-Leu-Phe-Asn by N-terminal amino acid sequence analysis. $IC_{50}$ value of purified ${\beta}$-secretase inhibitory peptide was $74.25{\mu}M$, and Lineweaver-Burk plots suggested that the peptide purified from sea hare muscle protein acts as a competitive inhibitor against ${\beta}$-secretase. Results of this study suggest that peptides derived from sea hare muscle may be beneficial as anti-dementia compounds in functional foods or as pharmaceuticals.

• Polymer(Korea)
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• v.38 no.4
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• pp.484-490
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• 2014

Reduced graphene oxide (RGO) was fabricated using gelatin as a reductant, and it could be stably dispersed in gelatin solution without aggregation. A series of RGO/gelatin composite films with various RGO contents were prepared by a solution-casting method. The structure and thermal properties of the RGO/gelatin composite films were characterized by UV-vis spectroscopy, Fourier transform infrared (FTIR) spectroscopy, X-ray diffraction (XRD), atomic force microscopy (AFM), scanning electron microscopy (SEM), differential scanning calorimeter (DSC) and thermal gravimetric analysis (TGA). The addition of RGO enhances the degree of crosslinking of gelatin films and decreases the swelling ability of the gelatin films in water, indicating that RGO/gelatin composite films have a better wet stability than gelatin films. The glass transition temperature ($T_g$) of gelatin films is also increased with the incorporation of RGO. The presence of RGO slightly increases the degradation temperature of gelatin films due to the very low content of RGO in the composite films. Since gelatin is a natural and nontoxic biomacromolecule, the RGO/gelatin composite films are expected to have potential applications in the biomedical field.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.41 no.3
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• pp.285-297
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• 2016

In this paper, a centralized mmWave-based multi-spot beam cellular system architecture having such a base station equipped with a plurality of beam-forming antennas, multi-layered dynamic cell configuration method as one of key concepts of this system operation and a mobility management method based on it are introduced. To estimate the performance of new system, system simulation was performed under the ideal environment without blockage. These results show the possibility that system capacity can be dramatically increased and mobility performance similar to the existing cellular system may be achieved.

• Bulletin of the Korean Chemical Society
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• v.35 no.10
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• pp.3015-3020
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• 2014

The behavior of benzo[a]pyrene-7,8-dione (BPQ) in aqueous solution and its interaction with native DNA was investigated using conventional absorption and linear dichroism (LD) spectroscopy. The appearance of a broad absorption maximum at long wavelengths and its proportional relationship to solvent polarizability suggested that BPQ adopts a aggregated state for all solutions examined. Disappearance of this absorption band at higher temperatures in aqueous solution also supported BPQ aggregation. When associated with DNA absorption spectral properties were essentially the same as that in aqueous solution. However, two isosbestic wavelengths were found in the concentration-dependent absorption spectrum of the BPQ-DNA complex, suggesting the presence of at least two or more DNA-bound BPQ species. Both species produced $LD^r$ spectra whose magnitude in BPQ absorption region is larger or comparable to that in the DNA absorption region, suggesting that the molecular BPQ plane is near perpendicular relative to the local DNA helical axis. Therefore, BPQ molecules are aligned along the DNA stem in both DNA-aggregated BPQ species.

• Proceedings of the IEEK Conference
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• summer
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• pp.193-198
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• 2004

In variety of environments for applications, wireless sensor networks have received increasing attention in the recent few years. But, sensor nodes have many limitations including battery power and communication range. These networks require robust wireless communicant protocols that are energy efficient and provide low latency. In this paper, we propose new protocol as is defined SCP. The key idea of SCP is that only one node which is defined as a Super-Cluster Header sends the combined data to the BS. We evaluated the effectiveness of SCP through experiments which have several parameter violations. Simulation results shows that performance of SCP is through better than other legacy protocol within the framework of energy cost, life time of the sensor network and fair distribution of the energy consumption.