• Asian Pacific Journal of Cancer Prevention
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• 제14권6호
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• pp.3461-3463
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• 2013

Background: Non-Hodgkin lymphoma (NHL) is a solid tumour of lymphocytes, important elements in the immune system. According to 2006 data, in Turkey the incidence was 6.5 per 100,000 in males, and 4.4 in females. The relationship between the use of pesticides and development of NHL has been extensively investigated in many studies, and it has been demonstrated that the risk of NHL is increased by exposure to such compounds. Antalya is a region of intensive agricultural activity. In this study, the relationship between the incidence of lymphoma in Antalya and the amount of pesticides employed was investigated. Materials and Methods: The study used data from 1995 to 2010 on the patients from the databank of TR Ministry of Health, Antalya Provincial Health Directorate, Cancer Registration Center and the patients who were histopathologically diagnosed with NHL during these years. Results: The relationship between the amount of pesticide used and the incidence was studied with the Spearman correlation analysis and the p value was found as 0.05. The correlation coefficient was 0.497. An increase in the NHL incidence over the years was identified, with a 2.42-fold increment found from 1995 to 2005 and a 2.77 fold elevation from 1995 to 2010. The use of pesticides increased 1.89 fold over the same period. Conclusions: Our study investigated the relationship of the pesticides used with NHL patients diagnosed during the same year. Since the time elapsing after exposure to pesticides until the development of cancer is not clear, no comparison can be made at present. We believe that the increase in use of pesticides since 1995 may be associated with the increase in the incidence of NHLand therefore that further studies on the issue including measurements of serum pesticide levels, are required.

• 대한물리의학회지
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• 제9권1호
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• pp.45-53
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• 2014

PURPOSE: In this study, we tried to find out what kind of exercise was more effective in sleep disorder by comparing melatonin in blood after applying low intensity with high intensity exercise to sleep disordered rats induced by experiment. METHODS: We used male Sprague-Dawley rats which were 8weeks old and weighted 300g. They were supplied with water and food without any restriction. We kept the room temperature at $25^{\circ}C$ and controld the length of day and night in 12 hours blocks, respectively. We divided the rats 60 into 2 groups. To one group we applied low intensity exercise, and to the other we applied high intensity exercise for 15minutes per day over a period of 4 weeks. We extracted the blood from abdominal aorta before, after exercise, moved into EDTA tube, performed centrifugation. We decanted the serum $200{\mu}l$ from the blood into microcentrifuge tube by samples and moved into polypropylene culture tubes with micro pipette. We split enzyme solution $50{\mu}l$ into the tubes with melatonin direct kits and make them react at $37^{\circ}C$ for 2 hours. We split assay buffer $50{\mu}l$ into each tube and mixed melatonin tracer $50{\mu}l$ and melatonin antiserum $50{\mu}l$, respectively. After we made them react in room temperature, we decanted the superficial layer with a centrifuge and measured the activity for 1 minute by competitive method with ${\gamma}$-counter equipment. We draw a standard curve through logit-log graph with CPM(counts per minute) and counted the melatonin by B/B0. We conducted independent t-test to examine the homogeneous of melatonin value of before low-intensity and high-intensity exercise. We performed paired t-test to compare before and after low-intensity and high-intensity exercise, respectively. We carried out independent t-test to compare melatonin value after low-intensity and high-intensity exercise. Significance level was .05. RESULTS: The results were as follows; firstly melatonin was more increased in the group who was exposed to high intensity exercise when we compared before to after high and low intensity exercise, respectively. Secondly, high intensity exercise was more effective than low intensity exercise when we compared the two. CONCLUSION: In conclusion, secretion of melatonin which is the material of sleep improvement could be promoted by high intensity exercise. Low intensity exercise acted as a stress rather than improving sleep and had a negative effect on the secretion of melatonin because the melatonin was affected by stress.

• Asian-Australasian Journal of Animal Sciences
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• 제24권10호
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• pp.1425-1434
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• 2011

This experiment was designed to evaluate the effects of the processing method of common vetch seed (CVS) (Vicia sativa) on laying performance, egg quality, metabolic parameters and liver histopatology during the peak production period in hens. Lohman layers, 46 wk of age in 6 replicate cages each containing 4 hens, were allocated randomly to one of four dietary treatments. Diets were control (C) diet containing no common vetch and experimental diets containing 25% raw common vetch (RCV), 25% soaked in water for 72 h with exchange of water every 24 h (SCV) and 25% soaked&boiled at $100^{\circ}C$ for 30 minute common vetch (SBCV). Inclusion of RCV into the diet deteriorated all laying performance variables. SCV did not alleviate the adverse effect of raw common vetch on feed intake, egg weight, feed conversion, final weight and weight change. SCV partially alleviated egg production (p<0.001). SBCV diminished the adverse effect on feed intake, egg weight, feed conversion, final weight and weight change compared to raw vicia sativa (p<0.001). No significant difference was detected between SBCV and the control group in terms of egg production, feed conversion, final weight and weight change. Regardless of the processing method, all the common vetch groups had lower shell strength compared to the control group. Haugh units did differ between all groups (p<0.001). Inclusion of RCV and SCV into the basal diet decreased triglyceride, cholesterol, total protein and serum glucose concentrations (p<0.001). Hovewer, inclusion of SBCV into the basal diet increased these parameters. Liver samples were stained with Hematoxylin and eosin (HE) and evaluated by light microscopy. A biopsy of native liver tissue was used as a control. No histopathologic finding was present in the control group. Raw V. sativa compared with the control caused lipid accumulations in hepatocytes, severe congestion of hepatic blood vessels, inflammation, increased numbers of Kupffer cells and sinusoidal dilatations. Whereas, the livers from groups given treated V. sativa showed only different degrees of sinusoidal dilatations. Findings from the present study point out the risk of increased hepatic damage due to use of raw Vicia sativa. Increasing treatment of V. sativa lead to a decrease of liver damages. Inclusion of raw and soaked vetch seeds in rations affected adversely all parameters examined in laying hens. But alleviation was observed when soaked and boiled vetch seeds (SBCV) were fed. The results of these experiments indicated that soaked&boiled Vicia sativa seeds may safely be used at a 25% level in rations of laying hens.

• Asian Pacific Journal of Cancer Prevention
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• 제16권15호
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• pp.6779-6782
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• 2015

Background: Chemoradiotherapy is an important treatment modality for lung cancers. The aim of this study was to investigate alterations in, as well as the interrelationship between, lung function and quality of life of patients receiving chemoradiotherapy due to locally advanced non-small cell lung cancer (NSCLC) and small cell lung cancer (SCLC) limited to the thorax. Materials and Methods: The study included patients receiving definitive chemoradiotherapy for lung carcinoma. The respiratory function of the patients was assessed by measuring forced expiratory volume in 1 s per unit (FEV1) and forced expiratory volume in 1s per unit of vital capacity (FEV1/VC) before, in the middle of and after treatment. During the study, EORTC QLQ C30 and LC13 questionnaires developed by the Committee of the European Organization for Research and Treatment of Cancer (EORTC) were employed to evaluate the quality of life on the same day as respiratory function tests (RFT). Findings: The study included 23 patients in total: 19 (82.6%) diagnosed with NSCLC and 4 (17.4%) with SCLC. The average percentage FEV1 was $55.6{\pm}21.8%$ in the pre-treatment period, $56.2{\pm}19.2%$ in the middle of treatment and $60.4{\pm}22%$ at the end of treatment. The improvement in functional scores, symptom scores and general health scores during treatment was not statistically significant (P= 0.568, P= 0.734, P= 0.680, P=0.757 respectively). Conclusions: Although this study showed an improvement in respiratory function and quality of life of patients during treatment with thoracic chemoradiotherapy, no statistically significant results were obtained. While evaluating the effectiveness of treatments for lung carcinoma, the effects of treatment on respiratory function and quality of life should be considered.

• PNF and Movement
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• 제14권3호
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• pp.237-244
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• 2016

Purpose: This case report examines the influence of proprioceptive neuromuscular facilitation (PNF) combined with a dynamic neuromuscular stabilization approach on balance in patients with cerebellar atrophy. Methods: The target subject of this case report was a 34-year-old woman who was informed of the purpose of this research and voluntarily agreed to participate in it. The case report conformed to research ethics based on the Helsinki Declaration. The target subject was confirmed to have cerebellar atrophy from an unknown cause in 2009 and was diagnosed with slight ataxia. At that time, she could carry out daily activities without physical therapy. On May 19, 2015, she suffered both a subdural hemorrhage (SDH) and subarachnoid hemorrhage (SAH) in a traffic accident. She was urgently moved to the emergency room and managed by nonsurgical treatment, and then, the cerebellar atrophy and ataxia gradually deteriorated. To evaluate the patient's balance capacity before and after intervention, the trunk impairment scale (TIS), trunk impairment scale (OLST) during eye-closing/opening, timed up and go test (TUG), and visual analogue scale (VAS) were conducted. The PNF intervention program was executed for 30 min, four times a week, for three weeks. Results: The TIS and OLST during eye-closing/opening were improved by as much as a point, by 8.15 s and 6.21 s, respectively, after applying the PNF program. TUG and VAS decreased by 1.33 s and 3 points, respectively, after intervention. According to the result, the OLST during eye-closing/opening and VAS improved remarkably in comparison with those before intervention. Conclusion: As the final result of the case report, PNF intervention combined with DNSA more effectively improved the static balance capacity, such as the OLST during eye-closing/opening and VAS, compared to the dynamic balance capacity. In addition, the intervention duration and period of the exercise program are recommended to be more than 1 h a day for four weeks considering the learning ability of a patient with cerebellar atrophy.

• 한국지역지리학회지
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• 제7권4호
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• pp.48-64
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• 2001

영남지방 비보의 기원은 가야와 신라의 불교적 비보사탑에서 비롯하며, 고려 및 조선조를 거치면서 국도(國都)에서 풍수적 비보의 성행은 영남지방 비보경관의 조성에 큰 영향을 끼친다. 비보의 확산양상은, 조선 초기까지는 수위(首位)의 공간적 위계(空間的 位階)를 지니는 국도(國都)(개성 한양)를 비보핵심지(裨補核心地)하여 주변지역(周邊地域)의 부 목 대도호부(府 牧 大都護府) 등 대읍(大邑)의 차위중심지(次位中心地)로 확산되고, 대읍(大邑)이 다시 비보중심지(裨補中心地)가 되어 순차적으로 인근 군현(郡縣) 단위의 중소 읍치(中小 邑治)로 비보가 확산되었다. 이윽고 조선 중기 이후 좌지사비(左地士族)들의 촌락 개척과 맞물려 읍치(邑治) 외곽의 주요 士族(사족)의 주거지로 비보가 파급되어 나갔다.

• 유통과학연구
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• 제12권9호
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• pp.113-123
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• 2014

Purpose - After Korea's Free Economic Zone (FEZ) system was launched in 2003, there have been many debates about upgrading it and its support systems. However, as of 2013, there were insufficient results. Further, upon the designation of the East Coast and Chungbuk as official FEZs from February 4, 2013 by the 56th the Commission, there is a concern that many people are in the area designated as FEZ 8. This study investigates Korea's new FEZ system as part of Korea's primary new economic development policy in the 21st century. Therefore, this study examines views on the weaknesses of the past ten years of FEZs so that Korea can expand its FEZ system. Research design, data, and methodology -Many countries have considered the FEZ as an economic special zone. By reviewing previous research models, this study provides an update using recent data and materials, until 2013, from the Center of Free Economic Zones. In previous studies, the lack of support systems was attributed to proposals to ensure operational autonomy and differentiation of each FEZ; however, the main cause cannot be solved through regulatory issues, as difficulties caused by the operational system are responsible for the problems. We wish to analyze the FEZ, specifically the operational system; this is the main issue of this study. Results - After the first FEZs were established, it became necessary to have basic plans, as investment results in 2013 compared to the same period this year led to lower earnings in the first half of 2014. We propose an improvement of the operational system because in the free economic zones, the operational system is the root cause of the underlying problem. The results of this research are as follows. The weak management of the FEZ system is influenced by weak investment, delayed development, foreigners' living facilities, benefits of foreign investments, the control tower's policy making decision process, quickness of the process of satisfying legal requirements, and support For the independence of FEZs. Conclusion - Local governments do not have legal rights over FEZ deregulation and investment industries. This study suggests that the local government should have more independence from the central government. Moreover, independent management committees are more effective for ensuring public rights, better employee responsibilities, and better-qualified personnel. The FEZ committee struggles to effectively manage the locations of FEZs, foreign investments, and related facilities under the control of the Ministry of Trade, Industry and Energy. Thus, the FEZ committee should be under either the Prime Minister's office or the Presidential committee, to control and effectively coordinate between the local and central governments. If the problem clearly applies to the operational system in 2013, it is necessary to provide materials and methods so that the results of the first half of 2014 can be computed despite the data limits and lack of resources, and the data can be analyzed in a more diachronic thesis.

• 생명과학회지
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• 제20권6호
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• pp.894-901
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• 2010

본 연구는 부산지역 결혼이주여성의 생식건강상태와 체성분 조성을 파악하여 결혼이주여성의 건강증진을 위한 기초자료를 제공하기 위해 수행된 서술적 조사연구이다. 연구대상은 부산시에 거주하고 있는 결혼이주여성 154명이었으며. 자료수집 기간은 2008년 7월 21일부터 2009년 7월 25일까지였다. 결혼이주여성의 일반적인 특성, 생식건강상태를 측정하기 위해 구조화된 설문지를 사용하였고 신체계측과 체성분 검사를 하였다. 대상자의 연령에 따라 체외수정 경험, 임신경험과 유산경험이 유의한 차이를 나타내었으며 대상자의 국적에 따라 월경, 월경 전 증후군, 지난 1년간 월경의 규칙성, 질 분비물에서의 냄새, 체외수정 시술경험, 분만경험, 모유수유경험이 유의한 차이를 보였다. 대상자의 한국 내 체류기간에 따라 체외수정 시술경험, 임신경험, 분만경험과 모유수유경험이 유의한 차이를 보였고 대상자의 종교유무에 따라 월경 전 증후군, 생식기감염 치료경험과 모유수유경험이 유의한 차이를 보였다. 대상자의 자녀유무에 따라 월경통, 임신경험, 분만경험, 출산합병증과 모유수유경험이 유의한 차이를 보였다. 대상자의 체지방률은 국적과 종교유무에 통계적으로 유의한 차이를 보였으며 체질량지수는 연령, 국적 및 체류기간에 따라 통계적으로 유의한 차이를 보였다. 허리와 엉덩이 둘레 비는 연령, 국적 및 종교유무에 따라 통계적으로 유의한 차이를 보였다. 결혼이주여성의 연령과 출신국가 별 특성을 고려한 체계적인 건강관리 및 영양관리 프로그램 개발이 요구된다.

• 기본간호학회지
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• 제21권3호
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• pp.311-318
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• 2014

Purpose: The purpose of this research was to assess the methodological quality of non-randomized studies published in the Journal of Korean Fundamentals of Nursing. Methods: A search of non-randomized studies assessing intervention effects was conducted among all articles published in the Journal of Korean Fundamentals of Nursing between 2011 and 2013. Articles were assessed for quality using the Methodological Index for Non Randomized Studies (MINORS). For each index item, the frequency and percentage of articles meeting the criteria were calculated, along with mean scores by research method, publication year, and research topic. Results: A total of 22 studies were included. The mean score for studies without control groups was 11.75 (range 0-16), and for those with control groups, 19.27 (range 0-24). Results show that improvement is needed on several items: "endpoints appropriate to the aim of the study," "unbiased assessment of the study endpoint," "follow-up period appropriate to the aim of the study," "loss to follow up less than 5%," and "contemporary groups." Conclusion: Although the quality of articles published in the Journal of Korean Fundamentals of Nursing has consistently increased, more emphasis should be placed on using rigorous research methods.

• 한국항해항만학회지
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• 제41권4호
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• pp.235-242
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• 2017

이익조정은 사적인 목적을 가지고 재무보고과정에 의도적으로 개입하거나, 이해관계자들에게 기업성과를 호도하는 일련의 과정 또는 선택을 의미한다. 해운기업의 경우 선박확보와 결부된 자본구조로 인해 부채계약을 위반할 가능성이 높고, 이에 따른 이익조정 동기 또한 타 산업에 비해 높은 특징을 가지게 된다. 이에 본 논문은 2007년 이후 87개 해운기업을 대상으로 해운기업의 이익관리여부를 확인함과 동시에 수정 Jones모형을 통해 도출된 재량적발생액과 자본구조변수와의 관계 및 해운기업의 이익조정행태를 알아보고자 하였다. 해운기업의 이익관리 가능성을 확인하기 위해 분포도와 차이분석 및 FGLS분석을 실시하였으며, 분석결과 0에 근접하여 손실을 본 기업들의 이익조정 즉, 이익관리 가능성을 관찰할 수 있었다. 또한 자본구조관련 변수와 재량적발생액에는 부(-)의 관련성이 관찰되어 국내 많은 연구들과 유사한 결과를 보여주었다. 현금흐름변수 또한 유의한 것으로 나타나, 국내기업의 현금흐름중시 경향이 자본구조와 재량적발생액사이에 부(-)의 관련성을 발생시킬 수 있다는 기존 연구를 뒷받침해 주었다. 해운기업의 이익관리행태에 대한 추가분석에서는 전기부채만기구조가 이익조정과 부(-)의 관련성을 보였으며, 부채비율이 급격히 증가한 집단에서 이익조정의 가능성이 더 큼을 확인할 수 있었다.