• Tuberculosis and Respiratory Diseases
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• v.55 no.1
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• pp.41-58
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• 2003

Background : The resurgence of tuberculosis and the widespread emergence of multidrug-resistant M. tuberculosis have emphasized the importance of rapid and accurate diagnostic procedures. Recently, the oligonucleotide chip has proven to be a useful tool in the rapid diagnosis of infectious diseases. The purpose of this study was to rapidly and accurately detect specific mutations in the rpoB, katG and rpsL genes associated with rifampin, isoniazid and streptomycin resistance in M. tuberculosis, respectively, using a single oligonucleotide chip. Method : For detection of drug-resistance, 7 wild-type and 13 mutant-type probes for rifampin, 2 wild-type and 3 mutant-type probes for isoniazid, and 2 wild-type and 2 mutant-type probes for streptomycin were designed and spotted onto glass slides. Fifty-five cultured samples of M. tuberculosis were amplified by PCR, and then underwent hybridization and scanning. Direct sequencing was done to verify the results from the oligonucleotide chip and to analyze the types of mutations. Result : Thirty-five cases out of 40 rifampin-resistant strains(~88%) had mutations in the rpoB gene. One case had a new mutation(D516F, GAC R TTC) and another known mutation together. Twenty cases out of 42 isoniazid-resistant strains(~50%) had mutations in the katG gene, while 7 cases out of 9 streptomycin-resistant strains(~78%) had mutations in the rpsL gene. From these results, the oligonucleotide chip was confirmed to be able to detect the most frequent mutations from the genes associated with rifampin, isoniazid and streptomycin resistance. The results proved that the drug-resistance detection probes were specific. When the results from the oligonucleotide chip and DNA sequencing were compared, the types of mutations were exactly matched. Conclusion : The diagnostic oligonucleotide chip with mutation specific probes for drug resistance is a very reliable and useful tool for the rapid and accurate diagnosis of drug resistance against rifampin, isoniazid and streptomycin in M. tuberculosis infections.

• Biotechnology and Bioprocess Engineering:BBE
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• v.8 no.2
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• pp.101-105
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• 2003

Recombinant bioluminescent bacteria were used to monitor and classify the to xicity of azo dyes. Two constitutive bioluminescent bacteria, Photobacterium phosphoreum and Es-Cherichia coli, E, coli GC2 (lac::luxCOABE), were used to detect the cellular toxicity of the azo dyes. In addition, four stress-inducible bioluminestent E. coli, DPD2794 (recA::luxCDABE), a DNA damage Sensitive strain; DPD2540 (fabA::luxCDABE), a membrane damage sensitive strain; DPD2511 (katG::luxCDABE), an oxidative damage sensitive strain; and TV1061 (grpE::luxCDABE), a protein damage sensitive strain, were used to provide information about the type of toxicity caused by crystal violet, the most toxic dye of the 16 azo dyes tested. These results suggest that azo dyes result in serious cellular toxicity in bacteria, and that toxicity monitoring and classific ation of some azo dyes, In the field, may be possible using these recombinant bioluminescent bacteria.

• BMB Reports
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• v.36 no.6
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• pp.608-610
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• 2003

Escherichia coli has two catalases, HPI and HPII. HPI is induced during logarithmic growth in response to low concentrations of hydrogen peroxide. This induction is OxyR-dependent. On the other hand, HPII is not peroxide-inducible but is induced in entry to the stationary phase. We demonstrate here that E. coli displayed higher HPI catalase activity when compared to the cultures that were grown in a normal medium, if grown in a medium supplemented with iron-citrate. Iron supplementation had no effect on HPII catalase. This increase of HPI activity was OxyR-independent and not observed in a ${\Delta}fur$ mutant. The physiological significance of the increase of HPI activity is unclear, but it appears that the katG gene that codes for HPI catalase is among the genes that are regulated by Fur.

• Physical Therapy Korea
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• v.7 no.1
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• pp.32-37
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• 2000

The purpose of this study is to determine the effects of exercise training on the strength and balance ability of the elderly. The results of this study are: 1) After 8 weeks exercise training, knee muscle strength showed a significant increment. 2) After exercise training, forward functional reach and balance index of KAT 2000 showed a significant increment. Results indicate that strengthening exercise can result in improved muscle strength and balance in the elderly. Further studies are required to show long-term effects of exercise training on the elderly.

• Journal of the Korean Society of Clothing and Textiles
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• v.2 no.2
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• pp.277-286
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• 1978

The history of the women's veil which was used to hide their face in Yi-Dynasty was discussed. The similar fashion of wearing veil was popular in T'ang China as Myok-li and Yoo-Mo, then it might have influenced the fashion of the women's dress of the Silla Dynasty. It was also found out that the custom was most popular in Koryo and then continued to Yi-Dynasty. The confucianism of Yi-Dynasty requested very strict moral obligation toward women that veil had to be worn by them whenever going out. It might not be their popular fashion but obligation. There were several types of veil so called; Neoul(라원) Jangott(장의) Suege-China(쓰개치마) Chun-eue(천의) Sak-kat(삿갓) Chun-mo(천모)etc., which were used as a part of formal dress for women. From the late 1930, when the new society started to accept women's activities, the customs of wearing veil had been vanishing from the women's dress.

• Proceedings of the Korea Information Processing Society Conference
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• 2010.11a
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• pp.966-968
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• 2010

최근 정보통신기술의 발전과 세계화의 진전으로 IT제조업의 생산 효율화를 통한 비용절감의 방안으로 각 생산공정의 국제분업이 이루어지게 되었다. 국제분업을 통해 국가는 비교우위의 생산요소에 집적을 통해 효율화를 이루게 된다. 하지만 이러한 국제분업을 통해 기술의 양극화 현상이 나타나게 되고 국제분업구조에서 기술중진국의 비교우위부문의 확보가 새로운 과제로 부상되었다. 따라서 기술중 진국이 장기적으로 국제분업구조에서 기술부문의 비교우위확보를 위해 민간부문과 공공부문에서 동시에 이루어져야한다.

• Proceedings of the Korea Information Processing Society Conference
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• 2010.04a
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• pp.680-682
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• 2010

IT서비스의 아웃소싱을 통해 기업은 핵심역량에 집중하므로써 비용절감을 통한 경쟁력확보를 위해 노력해왔다. 서비스데스크는 단순히 고객의 불만사항이나 장애처리를 담당하는 영역을 넘어 IT아웃소싱에서 고객사와 IT서비스 제공사의 단일접점 뿐만 아니라 IT서비스제공사간의 원활한 의사소통을 통해 협업을 이루어가고 있다. 신세계 이마트의 무인점포시스템과 에릭슨코리아의 토털IT아웃소싱의 사례 중심으로 서비스데스크의 역할과 기능을 살펴본다.

• The Bulletin of The Korean Astronomical Society
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• v.36 no.2
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• pp.116.2-116.2
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• 2011

We investigate Faraday rotation measure (RM) toward high Galactic latitudes due to the Galactic magnetic field (GMF). The Galactic contribution to RM comes from the global component and the turbulent component of the GMF, and we newly model the latter by incorporating data of MHD turbulence simulations. We find that for the turbulent velocity of ~50 km/s, the standard deviation of the RM due to the GMF toward high Galactic latitudes is close to the observed value, several rad m^{-2}. Yet, the predicted second-order structure function (SF) has values substantially smaller than the observed ones at separation angles of <~ several degree. This suggests that the intergalactic magnetic field (IGMF) significantly contributes to RM toward high Galactic latitudes, particularly at small angular scales. Our work proposes a strategy for surveys to explore the IGMF with LOFAR, ASKAP, MeerKAT, and SKA.

• The Journal of Korean Academy of Orthopedic Manual Physical Therapy
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• v.16 no.1
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• pp.37-42
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• 2010

Purpose : The purpose of this study was to evaluate the influence of sensory integration training on equilibrium ability in the college students of the twenties. Methods : The sensory integration training group(male: n=10, female: n=9) was measured an equilibrium ability by Kinesthetic Ability Trainer(KAT) at pre-intervention and post-intervention in 4weeks. Results : Mean value of eye close both leg standing and eye close one leg standing tests of the sensory integration training group were significantly reduced among the intervention period(p<.05). Conclusion : We were found that sensory integration training could reduce mean value of eye close both leg standing and eye close one leg standing tests and improve a balance for the college students of the twenties.

• The Bulletin of The Korean Astronomical Society
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• v.36 no.1
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• pp.85.1-85.1
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• 2011

Recently, Faraday rotation measure (RM) at high Galactic latitude has been investigated, partly to explore the Galactic magnetic fields and partly to study the extragalactic magnetic fields. The Galactic contribution to RM comes from the global component as well as the turbulent component. So far the turbulent field was used to be analytically modeled with a Kolmogorov-type power spectrum. Here, we present the initial results of the work where the turbulent field is modeled using data of MHD turbulence simulations. Our work is intended to be applied to simulations of RM surveys with LOFAR, ASKAP, MeerKAT, and SKA.